JP2019522017A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019522017A5 JP2019522017A5 JP2019503673A JP2019503673A JP2019522017A5 JP 2019522017 A5 JP2019522017 A5 JP 2019522017A5 JP 2019503673 A JP2019503673 A JP 2019503673A JP 2019503673 A JP2019503673 A JP 2019503673A JP 2019522017 A5 JP2019522017 A5 JP 2019522017A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- tissue
- ulcer
- thermolysin
- bacterial biofilm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001580 bacterial effect Effects 0.000 claims 14
- 210000001519 tissue Anatomy 0.000 claims 11
- 108090001109 Thermolysin Proteins 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 8
- 206010052428 Wound Diseases 0.000 claims 7
- 208000027418 Wounds and injury Diseases 0.000 claims 7
- 206010011985 Decubitus ulcer Diseases 0.000 claims 4
- 208000004210 Pressure Ulcer Diseases 0.000 claims 4
- 208000025865 Ulcer Diseases 0.000 claims 4
- 230000001684 chronic effect Effects 0.000 claims 4
- 231100000397 ulcer Toxicity 0.000 claims 4
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 230000009854 mucosal lesion Effects 0.000 claims 3
- 206010040882 skin lesion Diseases 0.000 claims 3
- 231100000444 skin lesion Toxicity 0.000 claims 3
- 208000008960 Diabetic foot Diseases 0.000 claims 2
- 208000000558 Varicose Ulcer Diseases 0.000 claims 2
- 230000008030 elimination Effects 0.000 claims 2
- 238000003379 elimination reaction Methods 0.000 claims 2
- 239000002121 nanofiber Substances 0.000 claims 2
- 229920005594 polymer fiber Polymers 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000032770 biofilm formation Effects 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 230000009841 epithelial lesion Effects 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000005003 heart tissue Anatomy 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 210000005092 tracheal tissue Anatomy 0.000 claims 1
- 210000001635 urinary tract Anatomy 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 210000001835 viscera Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022089557A JP2022111186A (ja) | 2016-07-27 | 2022-06-01 | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662367338P | 2016-07-27 | 2016-07-27 | |
| US62/367,338 | 2016-07-27 | ||
| PCT/IB2017/054535 WO2018020435A1 (en) | 2016-07-27 | 2017-07-26 | Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022089557A Division JP2022111186A (ja) | 2016-07-27 | 2022-06-01 | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019522017A JP2019522017A (ja) | 2019-08-08 |
| JP2019522017A5 true JP2019522017A5 (enExample) | 2020-08-06 |
| JP7127013B2 JP7127013B2 (ja) | 2022-08-29 |
Family
ID=59738382
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503673A Active JP7127013B2 (ja) | 2016-07-27 | 2017-07-26 | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 |
| JP2022089557A Pending JP2022111186A (ja) | 2016-07-27 | 2022-06-01 | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022089557A Pending JP2022111186A (ja) | 2016-07-27 | 2022-06-01 | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11628207B2 (enExample) |
| EP (1) | EP3490588A1 (enExample) |
| JP (2) | JP7127013B2 (enExample) |
| CN (1) | CN109475609A (enExample) |
| AU (1) | AU2017304271B2 (enExample) |
| CA (1) | CA3031866A1 (enExample) |
| WO (1) | WO2018020435A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017304271B2 (en) * | 2016-07-27 | 2024-07-18 | Smith & Nephew, Inc. | Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces |
| WO2018140707A1 (en) | 2017-01-30 | 2018-08-02 | Smith & Nephew, Inc. | Synergistic combination of thermolysin and an antibacterial agent to reduce eliminate bacterial biofilms from surfaces |
| US20220306968A1 (en) * | 2019-06-06 | 2022-09-29 | Danisco Us Inc | Methods and compositions for cleaning |
| PH12023550203A1 (en) * | 2020-07-27 | 2024-06-24 | Unilever Ip Holdings B V | Use of an enzyme and surfactant for inhibiting microorganisms |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4197291A (en) | 1974-01-08 | 1980-04-08 | Gerold K. V. Klein | Hydrolytic enzyme material |
| JPS5692217A (en) | 1979-12-26 | 1981-07-25 | Kowa Co | Easily absorbable enzyme preparation |
| IT1264322B (it) | 1992-07-30 | 1996-09-23 | Lanfranco Callegaro | Esteri di gellano autoreticolato, procedimento di preparazione e loro applicazioni farmaceutiche e biomedico-sanitarie |
| CA2106609A1 (en) * | 1992-09-28 | 1994-03-29 | Irene Yeatman Aldridge | Proteases to inhibit and remove biofilm |
| US5902600A (en) | 1992-12-21 | 1999-05-11 | Healthpoint, Ltd. | Hydrogel polymer wound dressing |
| DE19857237A1 (de) | 1997-12-23 | 1999-06-24 | Henkel Kgaa | Strahlenhärtbare Kaschierklebestoffe |
| US6395529B1 (en) | 1998-11-10 | 2002-05-28 | Novozymes Biotech, Inc. | Polypeptides having lactonohydrolase activity and nucleic acids encoding same |
| US6548556B2 (en) | 2000-12-27 | 2003-04-15 | Healthpoint, Ltd. | Stable enzymatic wound debrider |
| US6399092B1 (en) | 2000-12-27 | 2002-06-04 | Healthpoint, Ltd. | Anhydrous, hydrophilic absorbent wound dressing (tube) with antimicrobials or other pharmaceutically active agents |
| US20030026794A1 (en) | 2001-07-31 | 2003-02-06 | Howard Fein | Selective enzyme treatment of skin conditions |
| US6479060B1 (en) | 2001-09-04 | 2002-11-12 | Healthpoint, Ltd. | Elegant hydrogenated castor oil ointments |
| US20030198631A1 (en) | 2002-04-18 | 2003-10-23 | Healthpoint, Ltd. | Thermolysin enzymatic wound debrider |
| EP1578935A2 (en) | 2002-10-10 | 2005-09-28 | Diversa Corporation | Proteases, nucleic acids encoding them and methods for making and using them |
| FR2846665B1 (fr) * | 2002-10-31 | 2006-09-08 | Karine Marion | Procede d'elimination du biofilm |
| US20050079594A1 (en) * | 2002-10-31 | 2005-04-14 | Karine Marion | Method of removing a biofilm |
| US8821862B2 (en) | 2002-12-20 | 2014-09-02 | Kane Biotech Inc. | Soluble β-N-acetylglucosaminidase based antibiofilm compositions and uses thereof |
| US7294497B2 (en) | 2002-12-20 | 2007-11-13 | University Of Medicine And Dentistry Of New Jersey | Compositions and methods for enzymatic detachment of bacterial and fungal biofilms |
| US20100221237A1 (en) | 2003-03-26 | 2010-09-02 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
| US7785584B2 (en) | 2003-08-13 | 2010-08-31 | Healthpoint, Ltd. | Ointment wound spray |
| AU2004285558A1 (en) | 2003-10-29 | 2005-05-12 | Altus Pharmaceuticals Inc. | Non-pancreatic proteases for controlling plasma cholecystokinin (CCK) concentration and for treating pain |
| GB0326194D0 (en) | 2003-11-10 | 2003-12-17 | Univ Kent Canterbury | Proteins involved in signal transduction |
| US20080177217A1 (en) | 2004-05-14 | 2008-07-24 | Hans-Dietrich Polaschegg | Taurolidine Formulations and Delivery: Therapeutic Treatments and Antimicrobial Protection Against Bacterial Biofilm Formation |
| EP1666075A1 (en) | 2004-10-04 | 2006-06-07 | Switch Biotech Aktiengesellschaft | Wound dressing compositions, especially for delivery of protease inhibitors |
| IL165334A0 (en) | 2004-11-22 | 2006-01-15 | Mediwound Ltd | Debriding composition from bromelain and methods of producing same |
| US8066991B2 (en) | 2005-10-11 | 2011-11-29 | Amano Enzyme Usa Co., Ltd. | Enzyme inhibitors of PAI-1 |
| US8287858B2 (en) | 2006-08-10 | 2012-10-16 | Jon Barron | Proteolytic enzyme formulations |
| AT504159A1 (de) | 2006-08-16 | 2008-03-15 | Marlyn Nutraceuticals Inc | Verwendung von proteasen |
| CA2681621A1 (en) | 2007-03-23 | 2008-10-02 | Danisco Us Inc. | Enhanced amylase production by n-terminal addition to mature amylase protein |
| JP2008290966A (ja) | 2007-05-24 | 2008-12-04 | Michiharu Sasaki | 養毛剤 |
| PT2268142T (pt) * | 2007-11-27 | 2017-06-02 | Algipharma As | Utilização de oligómeros alginados no combate aos biofilmes |
| AT506095A1 (de) | 2007-12-03 | 2009-06-15 | Volopharm Gmbh | Verwendung von proteasen |
| US8309081B2 (en) | 2008-11-18 | 2012-11-13 | Scarguard Labs, Llc. | Composition and method for treatment of bruising |
| JP2010126710A (ja) * | 2008-12-01 | 2010-06-10 | Kao Corp | バイオフィルム除去剤組成物 |
| WO2010079209A2 (en) | 2009-01-08 | 2010-07-15 | Golub Alexandr A | Compositions for treating wounds and skin conditions |
| GB0905451D0 (en) | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
| CA2780756A1 (en) | 2009-11-23 | 2011-05-26 | Prothera, Inc. | Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions |
| JP5997612B2 (ja) | 2009-12-08 | 2016-09-28 | スミス アンド ネフュー オーソペディックス アーゲーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｏｒｔｈｏｐａｅｄｉｃｓ ＡＧ | 増幅された酵素活性の酵素創傷壊死組織除去組成物 |
| US8796009B2 (en) | 2010-06-21 | 2014-08-05 | Toyota Motor Engineering & Manufacturing North America, Inc. | Clearcoat containing thermolysin-like protease from Bacillus stearothermophilus for cleaning of insect body stains |
| US9121016B2 (en) * | 2011-09-09 | 2015-09-01 | Toyota Motor Engineering & Manufacturing North America, Inc. | Coatings containing polymer modified enzyme for stable self-cleaning of organic stains |
| CN103687610A (zh) | 2011-05-12 | 2014-03-26 | 史密夫和内修整形外科股份公司 | 含有蜂蜜曲霉蛋白酶的伤口清创组合物和使用其治疗伤口的方法 |
| US10058596B2 (en) | 2011-12-20 | 2018-08-28 | Kci Licensing, Inc. | Composition for enzymatic debridement |
| AU2013259360B2 (en) | 2012-05-11 | 2017-07-13 | Smith & Nephew, Inc. | Use of Seaprose to remove bacterial biofilm |
| CN109260465A (zh) | 2012-11-14 | 2019-01-25 | 史密夫和内修公司 | 稳定的嗜热菌蛋白酶水凝胶 |
| MX2015013244A (es) * | 2013-03-15 | 2016-04-15 | Smith & Nephew Inc | Pelicula soluble formadora de gel para suministrar agentes activos. |
| US10159688B2 (en) | 2013-03-15 | 2018-12-25 | M. Alphabet 3, L.L.C. | Methods and compositions for enhancing oxygen levels in tissues |
| WO2015155351A1 (en) | 2014-04-11 | 2015-10-15 | Novozymes A/S | Detergent composition |
| US20180289003A1 (en) | 2015-08-24 | 2018-10-11 | Smith & Nephew, Inc. | Synergistic antibacterial activity of medium polarity oils in combination with antibacterial agents on bacterial biofilms |
| AU2017304271B2 (en) * | 2016-07-27 | 2024-07-18 | Smith & Nephew, Inc. | Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces |
| WO2018140707A1 (en) * | 2017-01-30 | 2018-08-02 | Smith & Nephew, Inc. | Synergistic combination of thermolysin and an antibacterial agent to reduce eliminate bacterial biofilms from surfaces |
-
2017
- 2017-07-26 AU AU2017304271A patent/AU2017304271B2/en active Active
- 2017-07-26 WO PCT/IB2017/054535 patent/WO2018020435A1/en not_active Ceased
- 2017-07-26 JP JP2019503673A patent/JP7127013B2/ja active Active
- 2017-07-26 US US16/319,927 patent/US11628207B2/en active Active
- 2017-07-26 CA CA3031866A patent/CA3031866A1/en active Pending
- 2017-07-26 CN CN201780046178.1A patent/CN109475609A/zh active Pending
- 2017-07-26 EP EP17758624.5A patent/EP3490588A1/en active Pending
-
2022
- 2022-06-01 JP JP2022089557A patent/JP2022111186A/ja active Pending
-
2023
- 2023-03-13 US US18/120,726 patent/US20230346898A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Konop et al. | Certain aspects of silver and silver nanoparticles in wound care: a minireview | |
| JP2019522017A5 (enExample) | ||
| JP5128757B2 (ja) | 抗菌性プラスチック製品の製造方法 | |
| JP2005515029A5 (enExample) | ||
| WO2007062306A2 (en) | Methods for coating surfaces with antimicrobial agents | |
| MX2014007208A (es) | Modificacion en la superficie para cateteres de dialisis. | |
| JP2009517335A (ja) | 次亜ハロゲン酸組成物を用いた尿路感染（ｕｔｉ）を含む細菌・菌類感染の防止及び処理のためのシステム及び方法 | |
| CN112717191B (zh) | 一种可定制、功能性敷料的制备方法 | |
| US20220347138A1 (en) | Wound care product | |
| CN102504318A (zh) | 一种高效抗菌性气管插管导管的制备方法 | |
| Lee et al. | Nature-inspired surface modification strategies for implantable devices | |
| CN102389616A (zh) | 纳米银聚合物蜂巢结构覆膜抗菌医用导管 | |
| CN201431691Y (zh) | 一种抗菌亲水涂层导尿管 | |
| JP2022111186A (ja) | 表面から細菌バイオフィルムを低減または除去するためのサーモリシンの使用 | |
| CN209475350U (zh) | 一种抗菌及防黏连的腹腔引流管 | |
| CN204655582U (zh) | 一种水凝胶抗菌纱布敷料 | |
| CN105326535A (zh) | 一种医用吻合钉及其制备方法 | |
| WO2021019336A1 (en) | Antimicrobial compositions and articles comprising the same | |
| CN104874028A (zh) | 一种超滑抗菌导尿管及其制备方法 | |
| CN201949389U (zh) | 纳米银聚合物蜂巢结构覆膜抗菌医用导管 | |
| CN206261915U (zh) | 一种超滑镇痛导尿管 | |
| CN206044823U (zh) | 一种医用纱布 | |
| CN203815714U (zh) | 一种用杀菌抑菌透气性材料制作的创可贴 | |
| CN202376604U (zh) | 一种中心静脉导管 | |
| CN205698126U (zh) | 人工角膜 |