JP2019522006A5 - - Google Patents
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- Publication number
- JP2019522006A5 JP2019522006A5 JP2019500823A JP2019500823A JP2019522006A5 JP 2019522006 A5 JP2019522006 A5 JP 2019522006A5 JP 2019500823 A JP2019500823 A JP 2019500823A JP 2019500823 A JP2019500823 A JP 2019500823A JP 2019522006 A5 JP2019522006 A5 JP 2019522006A5
- Authority
- JP
- Japan
- Prior art keywords
- functional polymer
- medicament according
- hydrogel
- eye
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 45
- 229920001002 functional polymer Polymers 0.000 claims 42
- 230000002207 retinal effect Effects 0.000 claims 29
- 239000000017 hydrogel Substances 0.000 claims 21
- 206010038848 Retinal detachment Diseases 0.000 claims 9
- 229940079593 drug Drugs 0.000 claims 9
- 239000007788 liquid Substances 0.000 claims 9
- 229920001223 polyethylene glycol Polymers 0.000 claims 6
- 229920000249 biocompatible polymer Polymers 0.000 claims 5
- 150000002148 esters Chemical class 0.000 claims 5
- 125000005647 linker group Chemical group 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 5
- 238000002360 preparation method Methods 0.000 claims 5
- 230000004264 retinal detachment Effects 0.000 claims 5
- 208000002367 Retinal Perforations Diseases 0.000 claims 4
- 238000006065 biodegradation reaction Methods 0.000 claims 4
- 208000029233 macular holes Diseases 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 238000001356 surgical procedure Methods 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 208000001351 Epiretinal Membrane Diseases 0.000 claims 2
- 208000031471 Macular fibrosis Diseases 0.000 claims 2
- 206010025421 Macule Diseases 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 238000001879 gelation Methods 0.000 claims 2
- 230000004410 intraocular pressure Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 238000002271 resection Methods 0.000 claims 2
- 208000019793 rhegmatogenous retinal detachment Diseases 0.000 claims 2
- 238000001429 visible spectrum Methods 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022008684A JP2022040410A (ja) | 2016-07-13 | 2022-01-24 | 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662361746P | 2016-07-13 | 2016-07-13 | |
| US62/361,746 | 2016-07-13 | ||
| PCT/US2017/041947 WO2018013819A1 (en) | 2016-07-13 | 2017-07-13 | Methods and polymer compositions for treating retinal detachment and other ocular disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022008684A Division JP2022040410A (ja) | 2016-07-13 | 2022-01-24 | 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019522006A JP2019522006A (ja) | 2019-08-08 |
| JP2019522006A5 true JP2019522006A5 (enExample) | 2021-05-20 |
| JP7038697B2 JP7038697B2 (ja) | 2022-03-18 |
Family
ID=60952730
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019500823A Active JP7038697B2 (ja) | 2016-07-13 | 2017-07-13 | 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物 |
| JP2022008684A Pending JP2022040410A (ja) | 2016-07-13 | 2022-01-24 | 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022008684A Pending JP2022040410A (ja) | 2016-07-13 | 2022-01-24 | 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (9) | US20190224375A1 (enExample) |
| EP (2) | EP4371536A3 (enExample) |
| JP (2) | JP7038697B2 (enExample) |
| CN (1) | CN109641077A (enExample) |
| AU (1) | AU2017295715B2 (enExample) |
| BR (2) | BR112019000504B1 (enExample) |
| CA (1) | CA3030767C (enExample) |
| WO (1) | WO2018013819A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4371536A3 (en) | 2016-07-13 | 2024-08-21 | Massachusetts Eye and Ear Infirmary | Methods and polymer compositions for treating retinal detachment and other ocular disorders |
| CN111741776A (zh) * | 2018-01-12 | 2020-10-02 | 皮库斯治疗公司 | 用于治疗视网膜脱离和其他眼部病症的方法、含聚合物的制剂和聚合物组合物 |
| CN109692072B (zh) * | 2019-01-09 | 2021-07-09 | 中南大学湘雅二医院 | 一种用于孔源性视网膜脱离的脉络膜上腔加压水凝胶球囊装置 |
| EP3920986A4 (en) * | 2019-02-08 | 2022-10-26 | Ohio State Innovation Foundation | ANTIOXIDANT-RELEASING VITREOUS SUBSTITUTES AND THEIR USES |
| WO2022150497A1 (en) * | 2021-01-07 | 2022-07-14 | Pykus Therapeutics, Inc. | Extended-release hydrogel-drug formulations |
| WO2023097213A1 (en) * | 2021-11-24 | 2023-06-01 | Pykus Therapeutics, Inc. | Hydrogel formulations and methods and devices for focal administration of the same |
| WO2024054997A1 (en) * | 2022-09-09 | 2024-03-14 | University Of Virginia Patent Foundation | Inflammasome inhibition for neuroprotection |
| US12233157B1 (en) | 2024-07-24 | 2025-02-25 | Pykus Therapeutics, Inc. | Hydrogel formulations and methods and devices for administration of the same |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5258412A (en) * | 1992-03-09 | 1993-11-02 | Peyman Gholam A | Vitreous replacement |
| US5654349A (en) | 1994-07-22 | 1997-08-05 | Staar Surgical Company, Inc. | Biocompatible optically transparent polymeric material based upon collagen and method of making |
| US7115417B1 (en) * | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
| US7589107B2 (en) * | 2003-05-19 | 2009-09-15 | Othera Holding, Inc. | Amelioration of vitrectomy-induced cataracts |
| US20060141049A1 (en) | 2003-11-12 | 2006-06-29 | Allergan, Inc. | Triamcinolone compositions for intravitreal administration to treat ocular conditions |
| EP1719521A1 (en) * | 2004-01-30 | 2006-11-08 | Mitsubishi Pharma Corporation | Preventive and/or remedy for retinopathy |
| US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
| US7659260B2 (en) | 2005-01-14 | 2010-02-09 | Eddie Francis Kadrmas | Tamponade compositions and methods for retinal repair |
| WO2008008859A2 (en) | 2006-07-11 | 2008-01-17 | University Of Utah Research Foundation | Macromolecules modified with electrophilic groups and methods of making and using thereof |
| EP2099845B1 (en) | 2006-11-27 | 2020-12-23 | Actamax Surgical Materials LLC | Multi-functional polyalkylene oxides, hydrogels and tissue adhesives |
| CN101338036B (zh) | 2007-07-06 | 2010-11-03 | 常州百瑞吉生物医药有限公司 | 生物相容快速凝胶化水凝胶及其喷雾剂的制备方法 |
| US9125807B2 (en) * | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
| CN102049067A (zh) * | 2009-11-10 | 2011-05-11 | 清华大学 | 一种可原位交联的高分子水凝胶玻璃体替代材料 |
| US7833206B1 (en) * | 2010-02-02 | 2010-11-16 | Peregrine Surgical, Ltd. | Method and apparatus for disposable aspirator cassette |
| WO2011135400A1 (en) * | 2010-04-30 | 2011-11-03 | Indian Institute Of Technology Bombay | Nanoparticulate in-situ gels as vitreous humor substitutes for ocular diseases |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| CN101934089B (zh) * | 2010-09-01 | 2013-05-01 | 北京大学人民医院 | 一种可眼内注射的原位交联水凝胶在制备人工玻璃体中的应用 |
| CN109200013A (zh) | 2011-12-05 | 2019-01-15 | 因赛普特有限责任公司 | 医用有机凝胶方法和组合物 |
| EP2846847B1 (en) | 2012-05-11 | 2020-03-25 | C.P. Medical Corporation | Biocompatible hydrogel treatments for retinal detachment |
| CN102911493A (zh) * | 2012-09-28 | 2013-02-06 | 山东赛克赛斯药业科技有限公司 | 可生物降解的医用水凝胶及其制备方法与应用 |
| DE102013203289A1 (de) | 2013-02-27 | 2014-08-28 | Franz Baur | Verbindungsmittel |
| US9873769B2 (en) * | 2014-07-10 | 2018-01-23 | Cambridge Polymer Group, Inc. | Thiolated PEG-PVA hydrogels |
| WO2016049791A1 (zh) * | 2014-09-29 | 2016-04-07 | 清华大学 | 一种用于玻璃体替代材料的原位凝胶及其制备方法与应用 |
| WO2016100355A1 (en) * | 2014-12-15 | 2016-06-23 | The Regents Of The University Of Colorado, A Body Corporate | Biocompatible hydrogels, systems including the hydrogels, and methods of using and forming same |
| WO2016197005A1 (en) * | 2015-06-05 | 2016-12-08 | Kato Pharmaceuticals, Inc. | Extended release urea compositions |
| EP4371536A3 (en) | 2016-07-13 | 2024-08-21 | Massachusetts Eye and Ear Infirmary | Methods and polymer compositions for treating retinal detachment and other ocular disorders |
| CN111741776A (zh) | 2018-01-12 | 2020-10-02 | 皮库斯治疗公司 | 用于治疗视网膜脱离和其他眼部病症的方法、含聚合物的制剂和聚合物组合物 |
| WO2022150497A1 (en) | 2021-01-07 | 2022-07-14 | Pykus Therapeutics, Inc. | Extended-release hydrogel-drug formulations |
-
2017
- 2017-07-13 EP EP24167099.1A patent/EP4371536A3/en not_active Withdrawn
- 2017-07-13 EP EP17828468.3A patent/EP3484534A4/en active Pending
- 2017-07-13 JP JP2019500823A patent/JP7038697B2/ja active Active
- 2017-07-13 AU AU2017295715A patent/AU2017295715B2/en active Active
- 2017-07-13 CN CN201780043404.0A patent/CN109641077A/zh active Pending
- 2017-07-13 BR BR112019000504-8A patent/BR112019000504B1/pt active IP Right Grant
- 2017-07-13 US US16/317,101 patent/US20190224375A1/en not_active Abandoned
- 2017-07-13 WO PCT/US2017/041947 patent/WO2018013819A1/en not_active Ceased
- 2017-07-13 BR BR122021015728-6A patent/BR122021015728B1/pt active IP Right Grant
- 2017-07-13 CA CA3030767A patent/CA3030767C/en active Active
-
2019
- 2019-01-11 US US16/245,397 patent/US10874767B2/en active Active
-
2020
- 2020-11-19 US US16/952,209 patent/US20210077662A1/en not_active Abandoned
- 2020-11-19 US US16/952,211 patent/US10973954B2/en active Active
- 2020-11-19 US US16/952,214 patent/US10973955B2/en active Active
-
2021
- 2021-03-04 US US17/191,942 patent/US11077232B2/en active Active
-
2022
- 2022-01-13 US US17/575,396 patent/US11547779B2/en active Active
- 2022-01-24 JP JP2022008684A patent/JP2022040410A/ja active Pending
-
2023
- 2023-01-09 US US18/152,100 patent/US20230414838A1/en active Pending
-
2024
- 2024-02-21 US US18/583,696 patent/US20240245833A1/en not_active Abandoned
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