AU2017295715B2 - Methods and polymer compositions for treating retinal detachment and other ocular disorders - Google Patents

Methods and polymer compositions for treating retinal detachment and other ocular disorders Download PDF

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Publication number
AU2017295715B2
AU2017295715B2 AU2017295715A AU2017295715A AU2017295715B2 AU 2017295715 B2 AU2017295715 B2 AU 2017295715B2 AU 2017295715 A AU2017295715 A AU 2017295715A AU 2017295715 A AU2017295715 A AU 2017295715A AU 2017295715 B2 AU2017295715 B2 AU 2017295715B2
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AU
Australia
Prior art keywords
functional polymer
hydrogel
polymer
eye
nucleo
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AU2017295715A
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AU2017295715A1 (en
Inventor
James Anthony Stefater III
Tomasz Pawel Stryjewski
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Massachusetts Eye and Ear
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Massachusetts Eye and Ear Infirmary
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Publication of AU2017295715A1 publication Critical patent/AU2017295715A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AU2017295715A 2016-07-13 2017-07-13 Methods and polymer compositions for treating retinal detachment and other ocular disorders Active AU2017295715B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662361746P 2016-07-13 2016-07-13
US62/361,746 2016-07-13
PCT/US2017/041947 WO2018013819A1 (en) 2016-07-13 2017-07-13 Methods and polymer compositions for treating retinal detachment and other ocular disorders

Publications (2)

Publication Number Publication Date
AU2017295715A1 AU2017295715A1 (en) 2019-01-24
AU2017295715B2 true AU2017295715B2 (en) 2022-03-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017295715A Active AU2017295715B2 (en) 2016-07-13 2017-07-13 Methods and polymer compositions for treating retinal detachment and other ocular disorders

Country Status (8)

Country Link
US (9) US20190224375A1 (enExample)
EP (2) EP3484534A4 (enExample)
JP (2) JP7038697B2 (enExample)
CN (1) CN109641077A (enExample)
AU (1) AU2017295715B2 (enExample)
BR (2) BR122021015728B1 (enExample)
CA (1) CA3030767C (enExample)
WO (1) WO2018013819A1 (enExample)

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JP7038697B2 (ja) 2016-07-13 2022-03-18 マサチューセッツ アイ アンド イヤー インファーマリー 網膜剥離および他の眼性障害を治療するための方法およびポリマー組成物
WO2019140212A1 (en) * 2018-01-12 2019-07-18 Pykus Therapeutics, Inc. Methods and polymer-containing formulations for treating retinal detachment and other ocular disorders
CN109692072B (zh) * 2019-01-09 2021-07-09 中南大学湘雅二医院 一种用于孔源性视网膜脱离的脉络膜上腔加压水凝胶球囊装置
KR20210139250A (ko) * 2019-02-08 2021-11-22 오하이오 스테이트 이노베이션 파운데이션 항산화제-방출 유리체 대체물 및 이의 용도
WO2022150497A1 (en) * 2021-01-07 2022-07-14 Pykus Therapeutics, Inc. Extended-release hydrogel-drug formulations
WO2023097213A1 (en) * 2021-11-24 2023-06-01 Pykus Therapeutics, Inc. Hydrogel formulations and methods and devices for focal administration of the same
WO2024054997A1 (en) * 2022-09-09 2024-03-14 University Of Virginia Patent Foundation Inflammasome inhibition for neuroprotection
US12233157B1 (en) 2024-07-24 2025-02-25 Pykus Therapeutics, Inc. Hydrogel formulations and methods and devices for administration of the same

Citations (2)

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WO2013170195A1 (en) * 2012-05-11 2013-11-14 Medicus Biosciences, Llc Biocompatible hydrogel treatments for retinal detachment
US20160009872A1 (en) * 2014-07-10 2016-01-14 Cambridge Polymer Group, Inc. Thiolated peg-pva hydrogels

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US7589107B2 (en) * 2003-05-19 2009-09-15 Othera Holding, Inc. Amelioration of vitrectomy-induced cataracts
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WO2005072768A1 (ja) * 2004-01-30 2005-08-11 Mitsubishi Pharma Corporation 網膜障害の予防及び／又は治療剤
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US7659260B2 (en) 2005-01-14 2010-02-09 Eddie Francis Kadrmas Tamponade compositions and methods for retinal repair
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WO2008066787A2 (en) 2006-11-27 2008-06-05 E. I. Du Pont De Nemours And Company Multi-functional polyalkylene oxides, hydrogels and tissue adhesives
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WO2019140212A1 (en) 2018-01-12 2019-07-18 Pykus Therapeutics, Inc. Methods and polymer-containing formulations for treating retinal detachment and other ocular disorders
WO2022150497A1 (en) 2021-01-07 2022-07-14 Pykus Therapeutics, Inc. Extended-release hydrogel-drug formulations

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2013170195A1 (en) * 2012-05-11 2013-11-14 Medicus Biosciences, Llc Biocompatible hydrogel treatments for retinal detachment
US20160009872A1 (en) * 2014-07-10 2016-01-14 Cambridge Polymer Group, Inc. Thiolated peg-pva hydrogels

Also Published As

Publication number Publication date
EP4371536A3 (en) 2024-08-21
EP3484534A1 (en) 2019-05-22
CA3030767C (en) 2023-08-22
CN109641077A (zh) 2019-04-16
BR122021015728B1 (pt) 2022-02-22
BR112019000504A2 (pt) 2019-04-24
US20190175791A1 (en) 2019-06-13
US10973954B2 (en) 2021-04-13
AU2017295715A1 (en) 2019-01-24
US20190224375A1 (en) 2019-07-25
US11077232B2 (en) 2021-08-03
US10874767B2 (en) 2020-12-29
EP3484534A4 (en) 2020-03-18
US10973955B2 (en) 2021-04-13
US20240245833A1 (en) 2024-07-25
US20220133956A1 (en) 2022-05-05
BR112019000504B1 (pt) 2022-03-03
US20210077664A1 (en) 2021-03-18
WO2018013819A1 (en) 2018-01-18
EP4371536A2 (en) 2024-05-22
JP7038697B2 (ja) 2022-03-18
US11547779B2 (en) 2023-01-10
US20210187168A1 (en) 2021-06-24
US20210077662A1 (en) 2021-03-18
CA3030767A1 (en) 2018-01-18
JP2019522006A (ja) 2019-08-08
US20210077663A1 (en) 2021-03-18
JP2022040410A (ja) 2022-03-10
US20230414838A1 (en) 2023-12-28

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