|
DE2433883C2
(de)
*
|
1973-07-20 |
1986-03-27 |
Research Corp., New York, N.Y. |
Verwendung von physiologisch aktiven Polypeptiden
|
|
US4179337A
(en)
*
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
EP0083439B1
(de)
*
|
1981-12-31 |
1989-07-26 |
ASTA Pharma AG |
4-Sulfido-oxazaphosphorine und deren Verwendung bei der Krebsbekämpfung und zur Immunsuppression
|
|
JPS58183626A
(ja)
|
1982-04-21 |
1983-10-26 |
Nippon Oil Co Ltd |
白血病治療用ｌ−アスパラギナ−ゼ固定化剤
|
|
US4729957A
(en)
|
1984-12-13 |
1988-03-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Process for manufacture of L-asparaginase from erwinia chrysanthemi
|
|
US5122614A
(en)
|
1989-04-19 |
1992-06-16 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
AU5526690A
(en)
*
|
1989-04-19 |
1990-11-29 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
GB9017002D0
(en)
|
1990-08-02 |
1990-09-19 |
Health Lab Service Board |
Improved method for the purification of erwina l-asparaginase
|
|
US5618710A
(en)
*
|
1990-08-03 |
1997-04-08 |
Vertex Pharmaceuticals, Inc. |
Crosslinked enzyme crystals
|
|
TW197439B
(enExample)
|
1991-04-04 |
1993-01-01 |
Ueno Pharmaceutics Applic Res Co Ltd |
|
|
US5283253A
(en)
|
1991-09-23 |
1994-02-01 |
Florida State University |
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
|
|
AU3140093A
(en)
|
1991-11-22 |
1993-06-15 |
University Of Mississippi, The |
Synthesis and optical resolution of the taxol side chain and related compounds
|
|
US5200534A
(en)
|
1992-03-13 |
1993-04-06 |
University Of Florida |
Process for the preparation of taxol and 10-deacetyltaxol
|
|
EP0642586A4
(en)
|
1992-05-21 |
1995-11-29 |
Penn State Res Found |
CULTURAL -i (TAXUS) FABRIC AS A SOURCE OF TAXOL, RELATED TAXANS AND OTHER NEW ANTI-TUMOR / ANTI-VIRAL SUBSTANCES (01/20/94).
|
|
US5274137A
(en)
|
1992-06-23 |
1993-12-28 |
Nicolaou K C |
Intermediates for preparation of taxols
|
|
US5294637A
(en)
|
1992-07-01 |
1994-03-15 |
Bristol-Myers Squibb Company |
Fluoro taxols
|
|
US5202448A
(en)
|
1992-08-14 |
1993-04-13 |
Napro Biotherapeutics, Inc. |
Processes of converting taxanes into baccatin III
|
|
CA2100808A1
(en)
|
1992-10-01 |
1994-04-02 |
Vittorio Farina |
Deoxy paclitaxels
|
|
FR2696463B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696462B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696461B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
|
|
FR2696458B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Procédé de préparation de dérivés du taxane.
|
|
FR2696464B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
|
|
US5279949A
(en)
|
1992-12-07 |
1994-01-18 |
Board Of Trustees Operating Michigan State University |
Process for the isolation and purification of taxol and taxanes from Taxus spp
|
|
US6277828B1
(en)
|
1993-08-20 |
2001-08-21 |
Syntex (U.S.A.) Inc. |
Pharmaceutical formulations of nerve growth factor
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
US5415869A
(en)
|
1993-11-12 |
1995-05-16 |
The Research Foundation Of State University Of New York |
Taxol formulation
|
|
US5599902A
(en)
|
1994-11-10 |
1997-02-04 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Cancer inhibitory peptides
|
|
US6087151A
(en)
|
1995-02-08 |
2000-07-11 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
DNA coding for mammalian L-asparaginase
|
|
AU704973B2
(en)
|
1995-04-21 |
1999-05-13 |
Teikoku Hormone Mfg. Co., Ltd. |
Novel peptide derivatives
|
|
MX9800684A
(es)
*
|
1995-07-27 |
1998-04-30 |
Genentech Inc |
Formulacion de proteinas liofilizadas isotonicas estables.
|
|
US6537547B1
(en)
|
1996-06-07 |
2003-03-25 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
Polypeptides having L-asparaginase activity
|
|
US5821263A
(en)
|
1996-08-26 |
1998-10-13 |
Bristol-Myers Squibb Company |
Sulfenamide taxane derivatives
|
|
AU739028B2
(en)
|
1996-09-27 |
2001-10-04 |
Bristol-Myers Squibb Company |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
AU4966597A
(en)
|
1996-11-19 |
1998-06-10 |
Daiichi Pharmaceutical Co., Ltd. |
Taxol derivatives
|
|
US5977386A
(en)
|
1996-12-24 |
1999-11-02 |
Bristol-Myers Squibb Company |
6-thio-substituted paclitaxels
|
|
PL195642B1
(pl)
|
1997-04-28 |
2007-10-31 |
Lilly Co Eli |
Sposób przetwarzania wodnego roztworu aktywowanego białka C
|
|
ATE265226T1
(de)
|
1997-06-09 |
2004-05-15 |
Los Angeles Childrens Hospital |
Verwendung von wolinella succinogenes asparaginase zur behandlung von asparagin- abhängiger krankheiten
|
|
US6991788B1
(en)
|
1997-06-09 |
2006-01-31 |
Childrens Hospital Los Angeles |
Utilization of wolinella succinogenes asparaginase to treat diseases associated with asparagine dependence
|
|
AU3574097A
(en)
|
1997-06-20 |
1999-01-04 |
Baker Norton Pharmaceuticals, Inc. |
Soluble prodrugs of paclitaxel
|
|
US7288665B1
(en)
|
1997-08-18 |
2007-10-30 |
Florida State University |
Process for selective derivatization of taxanes
|
|
US5854051A
(en)
|
1997-09-15 |
1998-12-29 |
Heska Corporation |
Parasitic helminth asparaginase proteins, nucleic acid molecules, and uses thereof
|
|
JPH1192468A
(ja)
|
1997-09-17 |
1999-04-06 |
Yakult Honsha Co Ltd |
新規なタキサン誘導体
|
|
DE69729128T2
(de)
|
1997-10-08 |
2005-04-28 |
Bio Research Corporation Of Yokohama, Yokohama |
Taxoid-derivate und verfahren zu ihrer herstellung
|
|
US6180095B1
(en)
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
WO1999048535A1
(en)
|
1998-03-26 |
1999-09-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
|
ES2435141T3
(es)
|
1999-02-22 |
2013-12-18 |
University Of Connecticut |
Nuevas formulaciones de factor VIII libres de albúmina
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
CA2475738A1
(en)
|
2002-03-08 |
2003-09-18 |
Eli Lilly And Company |
Activated protein c formulations
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
ATE485331T1
(de)
|
2003-01-06 |
2010-11-15 |
Nektar Therapeutics |
Thiolselektive wasserlösliche polymerderivate
|
|
NZ572519A
(en)
|
2006-06-30 |
2011-06-30 |
Defiante Farmaceutica Sa |
Recombinant host for producing l-asparaginase ii
|
|
US20080260820A1
(en)
*
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
|
JP2010524447A
(ja)
|
2007-04-20 |
2010-07-22 |
ディーエスエム アイピー アセッツ ビー．ブイ． |
アスパラギナーゼ酵素変異体およびその使用
|
|
FI20070455A0
(fi)
|
2007-06-08 |
2007-06-08 |
Reagena Ltd Oy |
Menetelmä syöpäsairauksien tai tulehdussairauksien hoitoon
|
|
WO2011003633A1
(en)
|
2009-07-06 |
2011-01-13 |
Alize Pharma Ii |
Pegylated l-asparaginase
|
|
NZ605873A
(en)
|
2010-06-25 |
2015-02-27 |
Shire Human Genetic Therapies |
Methods and compositions for cns delivery of arylsulfatase a
|
|
WO2012028945A2
(en)
|
2010-09-01 |
2012-03-08 |
Indian Institute Of Technology, Dehli |
Mutants of l-asparagine
|
|
RU2441914C1
(ru)
|
2010-10-06 |
2012-02-10 |
Учреждение Российской академии медицинских наук Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича РАМН (ИБМХ РАМН) |
Способ получения субстанции рекомбинантной l-аспарагиназы erwinia carotovora
|
|
CN102138909B
(zh)
|
2010-12-30 |
2013-03-13 |
常州千红生化制药股份有限公司 |
门冬酰胺酶冻干粉针剂及其制备方法以及门冬酰胺酶溶解液
|
|
WO2013055699A1
(en)
|
2011-10-10 |
2013-04-18 |
Children's Hospital Los Angeles |
Novel asparaginase and methods for treating diseases associated with asparagine dependence
|
|
CN102657852A
(zh)
*
|
2012-05-22 |
2012-09-12 |
范铭琦 |
重组沃氏菌天门冬酰胺酶药物组合物及其制备法和应用
|