JP2019520377A - 二成分組成物 - Google Patents

二成分組成物 Download PDF

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Publication number
JP2019520377A
JP2019520377A JP2018569065A JP2018569065A JP2019520377A JP 2019520377 A JP2019520377 A JP 2019520377A JP 2018569065 A JP2018569065 A JP 2018569065A JP 2018569065 A JP2018569065 A JP 2018569065A JP 2019520377 A JP2019520377 A JP 2019520377A
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JP
Japan
Prior art keywords
component
acid
aqueous solution
component composition
asa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018569065A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019520377A5 (enExample
Inventor
ビョルン フレドリクソン、ヨン
ビョルン フレドリクソン、ヨン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asamedic AS
Original Assignee
Asamedic AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asamedic AS filed Critical Asamedic AS
Publication of JP2019520377A publication Critical patent/JP2019520377A/ja
Publication of JP2019520377A5 publication Critical patent/JP2019520377A5/ja
Priority to JP2022182537A priority Critical patent/JP7520941B2/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
JP2018569065A 2016-06-28 2017-06-28 二成分組成物 Pending JP2019520377A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022182537A JP7520941B2 (ja) 2016-06-28 2022-11-15 二成分組成物およびカプセル

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20161073 2016-06-28
NO20161073 2016-06-28
PCT/EP2017/065970 WO2018002124A1 (en) 2016-06-28 2017-06-28 Two-component composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022182537A Division JP7520941B2 (ja) 2016-06-28 2022-11-15 二成分組成物およびカプセル

Publications (2)

Publication Number Publication Date
JP2019520377A true JP2019520377A (ja) 2019-07-18
JP2019520377A5 JP2019520377A5 (enExample) 2020-07-27

Family

ID=59285173

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018569065A Pending JP2019520377A (ja) 2016-06-28 2017-06-28 二成分組成物
JP2022182537A Active JP7520941B2 (ja) 2016-06-28 2022-11-15 二成分組成物およびカプセル

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022182537A Active JP7520941B2 (ja) 2016-06-28 2022-11-15 二成分組成物およびカプセル

Country Status (25)

Country Link
US (3) US11918554B2 (enExample)
EP (2) EP3871677A1 (enExample)
JP (2) JP2019520377A (enExample)
KR (1) KR102397334B1 (enExample)
CN (2) CN109789152A (enExample)
AU (1) AU2017288465B2 (enExample)
BR (1) BR112018076553A2 (enExample)
CA (1) CA3027462A1 (enExample)
CY (1) CY1124724T1 (enExample)
DK (1) DK3474858T3 (enExample)
EA (1) EA201990093A1 (enExample)
ES (1) ES2897981T3 (enExample)
HR (1) HRP20211761T1 (enExample)
HU (1) HUE056659T2 (enExample)
IL (1) IL263982B (enExample)
LT (1) LT3474858T (enExample)
MX (1) MX388400B (enExample)
MY (1) MY195384A (enExample)
NZ (1) NZ749230A (enExample)
PL (1) PL3474858T3 (enExample)
PT (1) PT3474858T (enExample)
RS (1) RS62574B1 (enExample)
SI (1) SI3474858T1 (enExample)
SM (1) SMT202100645T1 (enExample)
WO (1) WO2018002124A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3474858T (lt) 2016-06-28 2021-12-27 Asamedic As Dviejų komponentų kompozicija, apimanti acetilsalicilo rūgštį
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt
EP3501523A1 (en) 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912894A (en) * 1959-11-02 1962-12-12 Guy Leopold Van Moorleghem Method for the preparing a solution of aspirin for injection and product obtained thereby
JPH03141224A (ja) * 1989-08-02 1991-06-17 David Arnold John 血小板凝集を抑制するための治療法および製剤
JPH07157432A (ja) * 1993-12-07 1995-06-20 Daikyo Yakuhin Kogyo Kk 貼付剤
JPH11222457A (ja) * 1998-02-02 1999-08-17 Sanei Kogyo Kk 芳香族カルボン酸類の水溶性化組成物及び溶解度向上化水溶液
WO2006104086A1 (ja) * 2005-03-28 2006-10-05 Kowa Co., Ltd. 血栓症治療剤
JP2008507574A (ja) * 2004-07-26 2008-03-13 フルニエ ラボラトリーズ アイルランド リミテッド 血小板凝集阻害剤及びフィブラート系薬剤を含む複合薬
JP2012526105A (ja) * 2009-05-08 2012-10-25 ゼアプリン ファーマシューティカルズ， インコーポレーテッド アセチルサリチル酸およびテアニンの水溶性共結晶を用いた静脈内用配合物

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AT222276B (de) * 1959-11-02 1962-07-10 Guy Leopold Van Moorleghem Verfahren zur Herstellung einer injizierbaren Lösung von Acetylsalicylsäure
FR304M (fr) * 1960-08-19 1961-03-20 Guy Soluté injectable d'aspirine et son procédé de fabrication.
FR2320759A1 (fr) 1975-08-11 1977-03-11 Union Pharma Scient Appl Solution d'acide acetylsalicylique extemporanee injectable
US5157030A (en) 1989-08-25 1992-10-20 Alexander Galat Rapidly soluble aspirin compositions and method
FR2712809B1 (fr) 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
GB9701160D0 (en) * 1997-01-21 1997-03-12 Parkinson Sidney Medicament dispenser
IT1292677B1 (it) 1997-02-28 1999-02-11 Bormioli Metalplast Spa Confezione per mantenere separati dei prodotti prima dell'uso.
US5776431A (en) 1997-03-26 1998-07-07 Galat; Alexander Water-soluble aspirin composition
NO309761B1 (no) * 1999-05-03 2001-03-26 Anders Aelveborn Beholder eller kapsel for adskilt oppbevaring av to- komponents blandbare materialer
GB0018322D0 (en) * 2000-07-27 2000-09-13 Boots Co Plc Pharmaceutical compositions
US7029701B2 (en) 2000-09-11 2006-04-18 Andrx Pharmaceuticals, Llc Composition for the treatment and prevention of ischemic events
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
EP1525765A1 (en) 2002-06-25 2005-04-27 Nokia Corporation Routing method and network element
ITMI20022619A1 (it) 2002-12-11 2004-06-12 Ind Italiana Integratori Trei S P A Preparazioni farmaceutiche ad uso veterinario contenenti acido acetilsalicilico in forma di polvere solubile tamponata.
CN1418635A (zh) * 2002-12-19 2003-05-21 王登之 治疗感冒发热的阿司匹林口腔崩解片及其制备方法
US20060292225A1 (en) 2005-06-24 2006-12-28 Felix Arthur M Water soluble analgesic formulations and methods for production
US20070092561A1 (en) 2005-06-24 2007-04-26 Don Milne Water-Soluble Aspirin Composition
US7614496B2 (en) 2005-08-29 2009-11-10 Steven Dvorak Aqueous solution of an analgesic and a dispenser therefor
WO2009007768A1 (en) 2007-07-06 2009-01-15 Gumlink A/S Compressed tablet comprising polyol
CN101632647A (zh) * 2008-07-21 2010-01-27 北京迈劲医药科技有限公司 阿司匹林与碱性药物组成的复方制剂的制备方法
US20100125242A1 (en) * 2008-11-15 2010-05-20 Pharmstar Pharmaceuticals, Inc. Emergency dose medication administration device
WO2010065936A1 (en) * 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
US8580853B2 (en) 2011-06-13 2013-11-12 Howard PHYKITT Analgesic composition and method of making the same
HUE039878T2 (hu) * 2012-09-25 2019-02-28 Bayer Pharma AG Regorafenib és acetilszalicilsav kombinációja kolorektális rák kezelésére
PT3060203T (pt) 2013-10-23 2017-10-27 Bayer Healthcare Llc Comprimido efervescente que contém um teor elevado de aspirina
EP2777802B1 (en) 2013-12-03 2016-03-16 Capsugel Belgium NV Multi-compartment dosage form articles
WO2017001468A1 (en) * 2015-07-02 2017-01-05 Asamedic As Two-component composition
LT3474858T (lt) 2016-06-28 2021-12-27 Asamedic As Dviejų komponentų kompozicija, apimanti acetilsalicilo rūgštį
EP3501523A1 (en) 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912894A (en) * 1959-11-02 1962-12-12 Guy Leopold Van Moorleghem Method for the preparing a solution of aspirin for injection and product obtained thereby
JPH03141224A (ja) * 1989-08-02 1991-06-17 David Arnold John 血小板凝集を抑制するための治療法および製剤
JPH07157432A (ja) * 1993-12-07 1995-06-20 Daikyo Yakuhin Kogyo Kk 貼付剤
JPH11222457A (ja) * 1998-02-02 1999-08-17 Sanei Kogyo Kk 芳香族カルボン酸類の水溶性化組成物及び溶解度向上化水溶液
JP2008507574A (ja) * 2004-07-26 2008-03-13 フルニエ ラボラトリーズ アイルランド リミテッド 血小板凝集阻害剤及びフィブラート系薬剤を含む複合薬
WO2006104086A1 (ja) * 2005-03-28 2006-10-05 Kowa Co., Ltd. 血栓症治療剤
JP2012526105A (ja) * 2009-05-08 2012-10-25 ゼアプリン ファーマシューティカルズ， インコーポレーテッド アセチルサリチル酸およびテアニンの水溶性共結晶を用いた静脈内用配合物

Also Published As

Publication number Publication date
MY195384A (en) 2023-01-18
DK3474858T3 (da) 2021-11-22
HUE056659T2 (hu) 2022-03-28
ES2897981T3 (es) 2022-03-03
BR112018076553A2 (pt) 2019-04-02
US11369581B2 (en) 2022-06-28
IL263982A (en) 2019-01-31
PL3474858T3 (pl) 2022-01-17
WO2018002124A1 (en) 2018-01-04
CA3027462A1 (en) 2018-01-04
MX388400B (es) 2025-03-20
CY1124724T1 (el) 2022-07-22
IL263982B (en) 2022-03-01
PT3474858T (pt) 2021-11-22
EA201990093A1 (ru) 2019-07-31
KR102397334B1 (ko) 2022-05-11
CN117982446A (zh) 2024-05-07
JP2023027071A (ja) 2023-03-01
KR20190040184A (ko) 2019-04-17
MX2018015965A (es) 2019-05-22
HRP20211761T1 (hr) 2022-02-18
AU2017288465A1 (en) 2019-01-17
US11918554B2 (en) 2024-03-05
NZ749230A (en) 2023-05-26
US20220218724A1 (en) 2022-07-14
SI3474858T1 (sl) 2022-01-31
US20210212976A1 (en) 2021-07-15
EP3871677A1 (en) 2021-09-01
JP7520941B2 (ja) 2024-07-23
SMT202100645T1 (it) 2022-01-10
US20240216318A1 (en) 2024-07-04
AU2017288465B2 (en) 2019-10-10
EP3474858B1 (en) 2021-08-18
EP3474858A1 (en) 2019-05-01
CN109789152A (zh) 2019-05-21
LT3474858T (lt) 2021-12-27
RS62574B1 (sr) 2021-12-31

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