BR112018076553A2 - composição de dois componentes. - Google Patents

composição de dois componentes.

Info

Publication number
BR112018076553A2
BR112018076553A2 BR112018076553-8A BR112018076553A BR112018076553A2 BR 112018076553 A2 BR112018076553 A2 BR 112018076553A2 BR 112018076553 A BR112018076553 A BR 112018076553A BR 112018076553 A2 BR112018076553 A2 BR 112018076553A2
Authority
BR
Brazil
Prior art keywords
component composition
aas
immediate
novel
providing
Prior art date
Application number
BR112018076553-8A
Other languages
English (en)
Inventor
Bjørn Fredrikson John
Original Assignee
Asamedic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asamedic As filed Critical Asamedic As
Publication of BR112018076553A2 publication Critical patent/BR112018076553A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093Containers having several compartments for products to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072Sealing capsules, e.g. rendering them tamper-proof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

a presente invenção refere-se a uma nova composição de dois componentes compreendendo ácido acetilsalicílico (aas) e que é particularmente útil no fornecimento de uma solução aquosa de aas para administração peroral imediata.
BR112018076553-8A 2016-06-28 2017-06-28 composição de dois componentes. BR112018076553A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20161073 2016-06-28
NO20161073 2016-06-28
PCT/EP2017/065970 WO2018002124A1 (en) 2016-06-28 2017-06-28 Two-component composition

Publications (1)

Publication Number Publication Date
BR112018076553A2 true BR112018076553A2 (pt) 2019-04-02

Family

ID=59285173

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018076553-8A BR112018076553A2 (pt) 2016-06-28 2017-06-28 composição de dois componentes.

Country Status (24)

Country Link
US (2) US11918554B2 (pt)
EP (2) EP3871677A1 (pt)
JP (2) JP2019520377A (pt)
KR (1) KR102397334B1 (pt)
CN (2) CN117982446A (pt)
AU (1) AU2017288465B2 (pt)
BR (1) BR112018076553A2 (pt)
CA (1) CA3027462A1 (pt)
CY (1) CY1124724T1 (pt)
DK (1) DK3474858T3 (pt)
EA (1) EA201990093A1 (pt)
ES (1) ES2897981T3 (pt)
HR (1) HRP20211761T1 (pt)
HU (1) HUE056659T2 (pt)
IL (1) IL263982B (pt)
LT (1) LT3474858T (pt)
MX (1) MX2018015965A (pt)
MY (1) MY195384A (pt)
NZ (1) NZ749230A (pt)
PL (1) PL3474858T3 (pt)
PT (1) PT3474858T (pt)
RS (1) RS62574B1 (pt)
SI (1) SI3474858T1 (pt)
WO (1) WO2018002124A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018002124A1 (en) 2016-06-28 2018-01-04 Asamedic As Two-component composition
EP3501523A1 (en) * 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation

Family Cites Families (34)

* Cited by examiner, † Cited by third party
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GB912894A (en) * 1959-11-02 1962-12-12 Guy Leopold Van Moorleghem Method for the preparing a solution of aspirin for injection and product obtained thereby
FR2320759A1 (fr) 1975-08-11 1977-03-11 Union Pharma Scient Appl Solution d'acide acetylsalicylique extemporanee injectable
AU632602B2 (en) * 1989-08-02 1993-01-07 John David Arnold Method and preparation for reducing risk of myocardial infarction
US5157030A (en) * 1989-08-25 1992-10-20 Alexander Galat Rapidly soluble aspirin compositions and method
FR2712809B1 (fr) * 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
JPH07157432A (ja) * 1993-12-07 1995-06-20 Daikyo Yakuhin Kogyo Kk 貼付剤
GB9701160D0 (en) 1997-01-21 1997-03-12 Parkinson Sidney Medicament dispenser
IT1292677B1 (it) 1997-02-28 1999-02-11 Bormioli Metalplast Spa Confezione per mantenere separati dei prodotti prima dell'uso.
US5776431A (en) 1997-03-26 1998-07-07 Galat; Alexander Water-soluble aspirin composition
JP4126405B2 (ja) * 1998-02-02 2008-07-30 甲陽ケミカル株式会社 芳香族カルボン酸類の溶解度向上化水溶液
NO309761B1 (no) 1999-05-03 2001-03-26 Anders Aelveborn Beholder eller kapsel for adskilt oppbevaring av to- komponents blandbare materialer
GB0018322D0 (en) 2000-07-27 2000-09-13 Boots Co Plc Pharmaceutical compositions
US7029701B2 (en) 2000-09-11 2006-04-18 Andrx Pharmaceuticals, Llc Composition for the treatment and prevention of ischemic events
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
AU2002311554A1 (en) 2002-06-25 2004-01-06 Nokia Corporation Routing method and network element
ITMI20022619A1 (it) 2002-12-11 2004-06-12 Ind Italiana Integratori Trei S P A Preparazioni farmaceutiche ad uso veterinario contenenti acido acetilsalicilico in forma di polvere solubile tamponata.
CN1418635A (zh) * 2002-12-19 2003-05-21 王登之 治疗感冒发热的阿司匹林口腔崩解片及其制备方法
EP1621200A1 (en) * 2004-07-26 2006-02-01 Fournier Laboratories Ireland Limited Pharmaceutical combinations containing an inhibitor of platelet aggregation and a fibrate
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WO2018002124A1 (en) 2016-06-28 2018-01-04 Asamedic As Two-component composition
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt
EP3501523A1 (en) 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt

Also Published As

Publication number Publication date
HUE056659T2 (hu) 2022-03-28
US11369581B2 (en) 2022-06-28
CN117982446A (zh) 2024-05-07
IL263982B (en) 2022-03-01
US20220218724A1 (en) 2022-07-14
LT3474858T (lt) 2021-12-27
MX2018015965A (es) 2019-05-22
US20210212976A1 (en) 2021-07-15
EP3474858A1 (en) 2019-05-01
MY195384A (en) 2023-01-18
WO2018002124A1 (en) 2018-01-04
AU2017288465A1 (en) 2019-01-17
KR102397334B1 (ko) 2022-05-11
SI3474858T1 (sl) 2022-01-31
KR20190040184A (ko) 2019-04-17
NZ749230A (en) 2023-05-26
CN109789152A (zh) 2019-05-21
DK3474858T3 (da) 2021-11-22
EP3871677A1 (en) 2021-09-01
EA201990093A1 (ru) 2019-07-31
CY1124724T1 (el) 2022-07-22
IL263982A (en) 2019-01-31
RS62574B1 (sr) 2021-12-31
US11918554B2 (en) 2024-03-05
PL3474858T3 (pl) 2022-01-17
CA3027462A1 (en) 2018-01-04
PT3474858T (pt) 2021-11-22
EP3474858B1 (en) 2021-08-18
HRP20211761T1 (hr) 2022-02-18
AU2017288465B2 (en) 2019-10-10
ES2897981T3 (es) 2022-03-03
JP2019520377A (ja) 2019-07-18
JP2023027071A (ja) 2023-03-01

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Legal Events

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]