JP2019519770A5 - - Google Patents

Download PDF

Info

Publication number
JP2019519770A5
JP2019519770A5 JP2018562324A JP2018562324A JP2019519770A5 JP 2019519770 A5 JP2019519770 A5 JP 2019519770A5 JP 2018562324 A JP2018562324 A JP 2018562324A JP 2018562324 A JP2018562324 A JP 2018562324A JP 2019519770 A5 JP2019519770 A5 JP 2019519770A5
Authority
JP
Japan
Prior art keywords
cells
biomarker
sequence
peripheral
lymphoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018562324A
Other languages
English (en)
Japanese (ja)
Other versions
JP7066639B2 (ja
JP2019519770A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2017/063045 external-priority patent/WO2017207574A1/en
Publication of JP2019519770A publication Critical patent/JP2019519770A/ja
Publication of JP2019519770A5 publication Critical patent/JP2019519770A5/ja
Priority to JP2022072884A priority Critical patent/JP7511806B2/ja
Application granted granted Critical
Publication of JP7066639B2 publication Critical patent/JP7066639B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018562324A 2016-05-30 2017-05-30 患者における抗cd19治療の治療的有用性を予測するための方法 Active JP7066639B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022072884A JP7511806B2 (ja) 2016-05-30 2022-04-27 患者における抗cd19治療の治療的有用性を予測するための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16171885 2016-05-30
EP16171885.3 2016-05-30
PCT/EP2017/063045 WO2017207574A1 (en) 2016-05-30 2017-05-30 Methods for predicting therapeutic benefit of anti-cd19 therapy in patients

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022072884A Division JP7511806B2 (ja) 2016-05-30 2022-04-27 患者における抗cd19治療の治療的有用性を予測するための方法

Publications (3)

Publication Number Publication Date
JP2019519770A JP2019519770A (ja) 2019-07-11
JP2019519770A5 true JP2019519770A5 (enExample) 2020-07-16
JP7066639B2 JP7066639B2 (ja) 2022-05-13

Family

ID=56116221

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018562324A Active JP7066639B2 (ja) 2016-05-30 2017-05-30 患者における抗cd19治療の治療的有用性を予測するための方法
JP2022072884A Active JP7511806B2 (ja) 2016-05-30 2022-04-27 患者における抗cd19治療の治療的有用性を予測するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022072884A Active JP7511806B2 (ja) 2016-05-30 2022-04-27 患者における抗cd19治療の治療的有用性を予測するための方法

Country Status (26)

Country Link
US (2) US20190195879A1 (enExample)
EP (2) EP3465214B1 (enExample)
JP (2) JP7066639B2 (enExample)
KR (1) KR102416144B1 (enExample)
CN (2) CN115932265B (enExample)
AU (1) AU2017272608B2 (enExample)
CY (1) CY1124768T1 (enExample)
DK (2) DK3465214T3 (enExample)
EA (1) EA201892542A1 (enExample)
ES (2) ES2981046T3 (enExample)
FI (1) FI3916392T3 (enExample)
HR (2) HRP20210938T1 (enExample)
HU (2) HUE054860T2 (enExample)
IL (1) IL263103B2 (enExample)
LT (2) LT3465214T (enExample)
MA (2) MA45124B1 (enExample)
MD (2) MD3465214T2 (enExample)
MX (2) MX388502B (enExample)
PL (2) PL3465214T3 (enExample)
PT (2) PT3465214T (enExample)
RS (2) RS62155B1 (enExample)
SG (2) SG10201911958SA (enExample)
SI (2) SI3916392T1 (enExample)
SM (2) SMT202100291T1 (enExample)
WO (1) WO2017207574A1 (enExample)
ZA (2) ZA201808647B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016311136B2 (en) 2015-08-21 2022-02-17 Incyte Corporation Combinations and uses thereof
SMT202100317T1 (it) 2016-06-27 2021-07-12 Morphosys Ag Formulazioni di anticorpi anti-cd19
WO2018078123A1 (en) 2016-10-28 2018-05-03 Morphosys Ag Combination of anti cd19 antibody with a bcl-2 inhibitor and uses thereof
KR20200030337A (ko) 2018-09-12 2020-03-20 주식회사 녹십자랩셀 종양 치료를 위한 항-cd 19 항체 및 자연살해세포를 포함하는 약학적 조합물
CN114072424A (zh) 2019-05-03 2022-02-18 莫佛塞斯公司 具有有限数量的nk细胞的患者中的抗cd19疗法
WO2021084062A1 (en) * 2019-10-31 2021-05-06 Morphosys Ag Anti-cd19 therapy in combination with lenalidomide for the treatment of leukemia or lymphoma
TW202131950A (zh) * 2019-10-31 2021-09-01 德商莫菲西斯公司 依序抗cd19療法
EP4168449A1 (en) * 2020-06-22 2023-04-26 MorphoSys AG Anti-tumor combination therapy comprising anti-cd19 antibody and polypeptides blocking the sirpa-cd47 innate immune checkpoint
AU2021391623A1 (en) * 2020-12-04 2023-06-29 Incyte Corporation Anti-cd19 combination therapy
WO2026024668A1 (en) * 2024-07-22 2026-01-29 Abbott Laboratories Method of determining a volume of a liquid in a sample

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
JP3614866B2 (ja) 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ,インコーポレイティド 人工抗体ポリペプチド
PT1974747E (pt) * 1998-08-11 2012-09-05 Biogen Idec Inc Terapias de combinação para linfomas de células b compreendendo a administração de anticorpo anti-cd20
JP4361273B2 (ja) 2001-02-27 2009-11-11 アメリカ合衆国 潜在的な血管形成阻害剤としてのサリドマイド類似体
WO2005016326A2 (en) 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
JP4733635B2 (ja) 2003-07-31 2011-07-27 イミューノメディクス、インコーポレイテッド 抗cd19抗体
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
PT1853718E (pt) * 2005-02-15 2015-11-12 Univ Duke Anticorpos anti-cd19 e usos em oncologia
WO2007002223A2 (en) 2005-06-20 2007-01-04 Medarex, Inc. Cd19 antibodies and their uses
AU2006332155B2 (en) 2005-12-30 2013-01-10 Cancer Research Technology Limited Anti-CD19 antibodies with reduced immunogenicity
RS53263B (sr) 2006-08-14 2014-08-29 Xencor Inc. Optimizovana antitela usmerena na cd19
US8323653B2 (en) 2006-09-08 2012-12-04 Medimmune, Llc Humanized anti-CD19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
US20100167315A1 (en) 2006-09-13 2010-07-01 Glycode Method for investigating the response to a treatment with a monoclonal antibody
CA2693053C (en) 2007-05-30 2021-01-05 Xencor, Inc. Methods and compositions for inhibiting cd32b expressing cells
CN101903403B (zh) 2007-10-19 2016-03-16 西雅图基因公司 Cd19结合剂及其应用
CA2753158A1 (en) 2009-02-23 2010-08-26 Glenmark Pharmaceuticals S.A. Humanized antibodies that bind to cd19 and their uses
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
WO2011147834A1 (en) 2010-05-26 2011-12-01 Roche Glycart Ag Antibodies against cd19 and uses thereof
EP2409993A1 (en) 2010-07-19 2012-01-25 International-Drug-Development-Biotech Anti-CD19 antibody having ADCC function with improved glycosylation profile
EP2409712A1 (en) 2010-07-19 2012-01-25 International-Drug-Development-Biotech Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile
SG190254A1 (en) 2010-11-15 2013-06-28 Medimmune Llc Combination therapy for b cell lymphomas
EP2524929A1 (en) 2011-05-17 2012-11-21 Sanofi Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
CA2841738C (en) * 2011-08-16 2022-12-06 Morphosys Ag Combination therapy with an anti-cd19 antibody and a purine analog
SG10201606785UA (en) 2011-08-16 2016-10-28 Morphosys Ag Combination therapy with an anti - cd19 antibody and a nitrogen mustard
EP2791165A4 (en) * 2011-12-12 2015-08-05 Pikamab Inc PREDICTING SENSITIVITY TO ANTIBODY MAINTENANCE THERAPY
US20130273032A1 (en) 2012-03-02 2013-10-17 Roche Glycart Ag Predictive biomarker for cancer treatment with adcc-enhanced antibodies
CA2935748A1 (en) * 2014-02-25 2015-09-03 Immunomedics, Inc. Humanized rfb4 anti-cd22 antibody
EP3157553A4 (en) * 2014-06-16 2018-02-28 Xencor, Inc. Treatment for chronic lymphocytic leukemia (cll)
US10969391B2 (en) 2014-07-11 2021-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing hematological cancers
JP6916741B2 (ja) 2015-05-26 2021-08-11 モルフォシス・アーゲー 抗cd19抗体およびブルトン型チロシンキナーゼ阻害剤の組み合わせ、およびその使用
AU2016311136B2 (en) 2015-08-21 2022-02-17 Incyte Corporation Combinations and uses thereof
SMT202100317T1 (it) 2016-06-27 2021-07-12 Morphosys Ag Formulazioni di anticorpi anti-cd19
WO2018078123A1 (en) 2016-10-28 2018-05-03 Morphosys Ag Combination of anti cd19 antibody with a bcl-2 inhibitor and uses thereof
HUE063119T2 (hu) 2017-05-31 2024-01-28 Morphosys Ag Kezelési paradigma anti-CD19 antitest és venetoclax kombinációs kezeléshez
KR20200030337A (ko) 2018-09-12 2020-03-20 주식회사 녹십자랩셀 종양 치료를 위한 항-cd 19 항체 및 자연살해세포를 포함하는 약학적 조합물
CN114072424A (zh) 2019-05-03 2022-02-18 莫佛塞斯公司 具有有限数量的nk细胞的患者中的抗cd19疗法
LT4051710T (lt) 2019-10-31 2026-03-10 Incyte Corporation Priešnavikinė kompleksinė terapija, apimanti anti-cd19 antikūną ir gama delta ląsteles
TW202131950A (zh) 2019-10-31 2021-09-01 德商莫菲西斯公司 依序抗cd19療法
WO2021084062A1 (en) 2019-10-31 2021-05-06 Morphosys Ag Anti-cd19 therapy in combination with lenalidomide for the treatment of leukemia or lymphoma
EP4168449A1 (en) 2020-06-22 2023-04-26 MorphoSys AG Anti-tumor combination therapy comprising anti-cd19 antibody and polypeptides blocking the sirpa-cd47 innate immune checkpoint
AU2021391623A1 (en) 2020-12-04 2023-06-29 Incyte Corporation Anti-cd19 combination therapy
US20230357392A1 (en) 2021-12-22 2023-11-09 Morphosys Ag Treatment Paradigm for an Anti-CD19 Antibody Therapy

Similar Documents

Publication Publication Date Title
JP2023093495A5 (enExample)
Barnes et al. Evaluation of the addition of rituximab to CODOX-M/IVAC for Burkitt's lymphoma: a retrospective analysis
FI3916392T3 (fi) Menetelmiä cd19-vasta-ainehoidon terapeuttisen hyödyn ennakoimiseksi potilailla
Withers et al. Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells
Roufosse et al. Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome
JP2022002520A5 (enExample)
Gianni et al. Long-term remission in mantle cell lymphoma following high-dose sequential chemotherapy and in vivo rituximab-purged stem cell autografting (R-HDS regimen)
JP2022119854A5 (enExample)
RU2019113370A (ru) Комбинация антитела CD19 с ингибитором BCL-2 и пути ее применения
JP2013542194A5 (enExample)
JP2021523213A5 (enExample)
Intongkam et al. Efficacy and safety of hepatitis B vaccination in rheumatoid arthritis patients receiving disease-modifying antirheumatic drugs and/or biologics therapy
RU2014103490A (ru) Комбинированная терапия с помощью антитела к cd19 и аналога пурина
FI3110440T3 (fi) Anti-cd38-vasta-aineita akuutin lymfaattisen leukemian hoitamiseksi
RU2018107929A (ru) Комбинации и их использование
JP2018021031A5 (enExample)
FI3699198T3 (fi) Menetelmiä kasvaimen hoitoon bispesifistä CD3XCD20-vasta-ainetta käyttämällä
HRP20210945T1 (hr) Formulacije protutijela anti-cd19
RU2014103492A (ru) Комбинированная терапия антителом к cd19 и азотистым ипритом
JP2022532519A5 (enExample)
JP2012519707A5 (enExample)
JP2019517485A5 (enExample)
Verschoor et al. MicroRNA-155 is required for clearance of Streptococcus pneumoniae from the nasopharynx
JP2022554324A5 (enExample)
WO2016130572A3 (en) Methods of determining levels of exposure to radiation and uses thereof