JP2019518028A5 - - Google Patents

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JP2019518028A5
JP2019518028A5 JP2018564286A JP2018564286A JP2019518028A5 JP 2019518028 A5 JP2019518028 A5 JP 2019518028A5 JP 2018564286 A JP2018564286 A JP 2018564286A JP 2018564286 A JP2018564286 A JP 2018564286A JP 2019518028 A5 JP2019518028 A5 JP 2019518028A5
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JP
Japan
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eculizumab
dsrna
administering
sense strand
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JP2018564286A
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JP2019518028A (ja
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Priority claimed from PCT/US2017/036775 external-priority patent/WO2017214518A1/en
Publication of JP2019518028A publication Critical patent/JP2019518028A/ja
Publication of JP2019518028A5 publication Critical patent/JP2019518028A5/ja
Priority to JP2021214344A priority Critical patent/JP2022050510A/ja
Priority to JP2023123022A priority patent/JP2023156369A/ja
Priority to JP2025005272A priority patent/JP2025081296A/ja
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JP2018564286A 2016-06-10 2017-06-09 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法 Pending JP2019518028A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021214344A JP2022050510A (ja) 2016-06-10 2021-12-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2023123022A JP2023156369A (ja) 2016-06-10 2023-07-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2025005272A JP2025081296A (ja) 2016-06-10 2025-01-15 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662348564P 2016-06-10 2016-06-10
US62/348,564 2016-06-10
US201662429448P 2016-12-02 2016-12-02
US62/429,448 2016-12-02
PCT/US2017/036775 WO2017214518A1 (en) 2016-06-10 2017-06-09 COMPLETMENT COMPONENT C5 iRNA COMPOSTIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)

Related Child Applications (1)

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JP2021214344A Division JP2022050510A (ja) 2016-06-10 2021-12-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法

Publications (2)

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JP2019518028A JP2019518028A (ja) 2019-06-27
JP2019518028A5 true JP2019518028A5 (https=) 2020-07-09

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Application Number Title Priority Date Filing Date
JP2018564286A Pending JP2019518028A (ja) 2016-06-10 2017-06-09 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2021214344A Pending JP2022050510A (ja) 2016-06-10 2021-12-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2023123022A Pending JP2023156369A (ja) 2016-06-10 2023-07-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2025005272A Pending JP2025081296A (ja) 2016-06-10 2025-01-15 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法

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JP2021214344A Pending JP2022050510A (ja) 2016-06-10 2021-12-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2023123022A Pending JP2023156369A (ja) 2016-06-10 2023-07-28 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法
JP2025005272A Pending JP2025081296A (ja) 2016-06-10 2025-01-15 補体成分C5iRNA組成物及び発作性夜間血色素尿症(PNH)を処置するためのその使用方法

Country Status (4)

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US (3) US20190256845A1 (https=)
EP (1) EP3469083A1 (https=)
JP (4) JP2019518028A (https=)
WO (1) WO2017214518A1 (https=)

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TW201620526A (zh) 2014-06-17 2016-06-16 愛羅海德研究公司 用於抑制α-1抗胰蛋白酶基因表現之組合物及方法
ES2984352T3 (es) 2016-06-14 2024-10-29 Regeneron Pharma Anticuerpos anti-C5 y usos de los mismos
BR112019014282A2 (pt) 2017-01-10 2020-03-03 Arrowhead Pharmaceuticals, Inc. Agentes de rnai de antitripsina (aat) alfa-1, composições incluindo agentes de rnai de aat, e métodos de uso
MA51147A (fr) 2017-12-13 2021-03-24 Regeneron Pharma Associations d'anticorps anti-c5 et utilisations associées
CA3086485A1 (en) * 2017-12-21 2019-06-27 Alnylam Pharmaceuticals, Inc. Chirally-enriched double-stranded rna agents
US10526603B1 (en) * 2018-10-26 2020-01-07 Eisai R&D Management Co., Ltd. Double-stranded ribonucleic acid capable of suppressing expression of complement C5
MX2021015003A (es) * 2019-06-06 2022-01-24 Arrowhead Pharmaceuticals Inc Metodos para el tratamiento de la deficiencia de alfa-1 antitripsina (aatd).
JP6961860B1 (ja) 2019-12-26 2021-11-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 補体c5の発現を抑制する二本鎖リボ核酸を含む医薬組成物
JP6918197B2 (ja) * 2019-12-26 2021-08-11 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂質複合体を含む医薬組成物及び脂質ナノ粒子を含む医薬組成物
JPWO2025143001A1 (https=) * 2023-12-27 2025-07-03
WO2025148349A1 (zh) * 2024-01-08 2025-07-17 润佳(上海)医药技术有限公司 一种抑制C5基因表达的dsRNA及其用途

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