JP2019514908A5 - - Google Patents
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- Publication number
- JP2019514908A5 JP2019514908A5 JP2018556275A JP2018556275A JP2019514908A5 JP 2019514908 A5 JP2019514908 A5 JP 2019514908A5 JP 2018556275 A JP2018556275 A JP 2018556275A JP 2018556275 A JP2018556275 A JP 2018556275A JP 2019514908 A5 JP2019514908 A5 JP 2019514908A5
- Authority
- JP
- Japan
- Prior art keywords
- hbd
- medicament according
- motomeko
- defensins
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201670276 | 2016-04-29 | ||
| DKPA201670276 | 2016-04-29 | ||
| DKPA201670484 | 2016-07-01 | ||
| DKPA201670484 | 2016-07-01 | ||
| PCT/DK2017/050132 WO2017186250A1 (en) | 2016-04-29 | 2017-04-28 | Treatment of liver, biliary tract and pancreatic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019514908A JP2019514908A (ja) | 2019-06-06 |
| JP2019514908A5 true JP2019514908A5 (https=) | 2020-06-11 |
Family
ID=58992579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556275A Ceased JP2019514908A (ja) | 2016-04-29 | 2017-04-28 | 肝臓、胆管および膵臓の障害の治療 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12076368B2 (https=) |
| EP (1) | EP3448409B1 (https=) |
| JP (1) | JP2019514908A (https=) |
| KR (1) | KR102465341B1 (https=) |
| CN (1) | CN109414474B (https=) |
| AU (1) | AU2017258242B2 (https=) |
| BR (1) | BR112018071972A2 (https=) |
| CA (1) | CA3022497A1 (https=) |
| ES (1) | ES3057685T3 (https=) |
| PL (1) | PL3448409T3 (https=) |
| RU (1) | RU2740913C2 (https=) |
| SG (1) | SG11201809086YA (https=) |
| WO (1) | WO2017186250A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102244161B1 (ko) * | 2018-08-31 | 2021-04-26 | 주식회사 나이벡 | 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도 |
| JP7479381B2 (ja) * | 2019-01-07 | 2024-05-08 | アエスクルス バイオ エーピーエス | 治療または予防に使用するためのディフェンシン断片 |
| CN110279851A (zh) * | 2019-07-05 | 2019-09-27 | 浙江大学 | Defa4细胞因子在制备治疗肝功能衰竭药剂中的应用 |
| CN114058694A (zh) * | 2021-11-29 | 2022-02-18 | 上海市普陀区中心医院 | Trpv1在筛选或制备预防、缓解和/或治疗肝脏疾病的药物中的应用 |
| KR102735773B1 (ko) * | 2022-11-10 | 2024-11-27 | 을지대학교 산학협력단 | 혈액 내 단백질 바이오마커를 포함하는 암 진단용 키트 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| CA2487895A1 (en) | 2002-05-31 | 2003-12-11 | Ciphergen Biosystems, Inc. | Defensins: use as antiviral agents |
| US7528107B2 (en) | 2005-11-30 | 2009-05-05 | Auburn University | Methods of treating inflammation in mammalian tissues comprising administering human alpha-defensins |
| WO2007081486A2 (en) | 2005-12-15 | 2007-07-19 | Ventria Bioscience | Oral administration of defensins to treat intestinal diseases |
| US20100104529A1 (en) | 2006-05-01 | 2010-04-29 | England Robert L | TNF-alpha VACCINE FOR TREATING DISEASE CONDITIONS MEDIATED BY PATHOLOGICAL TNF-alpha |
| JP2009541287A (ja) * | 2006-06-20 | 2009-11-26 | リポペプチド・アクチエボラーグ | 抗癌剤としてのカテリシジン抗菌タンパク質(hCAP18)の使用 |
| WO2008115390A2 (en) * | 2007-03-16 | 2008-09-25 | The Hamner Institutes For Health Sciences | Methods of using defensins to treat diabetes |
| AU2009209565B2 (en) | 2008-02-01 | 2013-09-19 | Ascendis Pharma As | Prodrug comprising a self-cleavable linker |
| SG172709A1 (en) * | 2008-07-18 | 2011-07-28 | Novozymes Adenium Biotech As | Treatment of inflammatory bowel diseases with mammal beta defensins |
| AP2011005537A0 (en) | 2008-07-18 | 2011-02-28 | Novozymes Adenium Biotech As | Treatment of inflammatory diseases with mammal beta defensins. |
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| US8410049B2 (en) | 2009-10-28 | 2013-04-02 | Cebix | Methods and kits for preventing hypoglycemia |
| US20110311601A1 (en) | 2010-06-22 | 2011-12-22 | Michael Kleine | Antimicrobial medical devices |
| DE102010040153A1 (de) | 2010-09-02 | 2012-03-08 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Stoffkombination zur Behandlung von entzündlichen oder infektiösen Erkrankungen |
| WO2012177929A2 (en) | 2011-06-24 | 2012-12-27 | Amylin Pharmaceuticals, Inc. | Methods for treating diabetes with extended release formulations of glp-1 receptor agonists |
| WO2013006692A2 (en) * | 2011-07-06 | 2013-01-10 | The General Hospital Corporation | Methods of treatment using a pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1) |
| JP6219277B2 (ja) | 2011-07-08 | 2017-10-25 | ディフェンシン セラピューティクス アンパルトセルスカブDefensin Therapeutics Aps | 炎症性腸疾患の経口治療 |
| US20130052213A1 (en) | 2011-08-19 | 2013-02-28 | Novozymes A/S | Novel immunomodulatory peptide |
| JP2015533483A (ja) * | 2012-09-07 | 2015-11-26 | サノフイ | メタボリックシンドロームを治療するための融合タンパク質 |
| CN104971343B (zh) * | 2015-07-13 | 2018-02-02 | 韩源平 | 防御素在制备治疗代谢综合征药物方面的应用 |
| CN105504063B (zh) * | 2015-10-19 | 2019-10-01 | 中国医学科学院医药生物技术研究所 | 一类防御素-白蛋白的抗肿瘤融合蛋白及其制备和应用 |
| BR112018015170A2 (pt) | 2016-01-26 | 2018-12-18 | Defensin Therapeutics Aps | métodos para tratamento de doenças, para promoção de crescimento magro, para tratamento ou normalização de uma microbiota disbiótica no intestino, para aumentar riqueza gênica da microbiota intestinal, para aumentar número de filos da microbiota intestinal, para aumentar produção de ácidos graxos de cadeia curta da microbiota intestinal/metaboloma, para aumentar número de bactérias, para diminuir número de bactérias, defensina a, defensina ss, ou um fragmento bioativo das mesmas, e, defensina a e/ou defensina ss e/ou um glp-1/análogo de glp-1. |
| WO2017185549A1 (zh) * | 2016-07-30 | 2017-11-02 | 邦泰生物工程(深圳)有限公司 | 一种制备烟酰胺单核苷酸的方法2 |
| CN114075585A (zh) * | 2020-08-18 | 2022-02-22 | 弈柯莱生物科技(上海)股份有限公司 | 一种β-烟酰胺单核苷酸的制备方法 |
| CN112795606B (zh) * | 2021-04-14 | 2021-07-27 | 深圳瑞德林生物技术有限公司 | 一种β-烟酰胺单核苷酸的酶催化合成方法 |
| CN114107160B (zh) * | 2021-12-27 | 2025-04-25 | 浙江英沃迪生物科技有限公司 | 一种烟酰胺核糖激酶基因工程菌及其应用 |
-
2017
- 2017-04-28 CN CN201780039341.1A patent/CN109414474B/zh active Active
- 2017-04-28 US US16/097,072 patent/US12076368B2/en active Active
- 2017-04-28 ES ES17727094T patent/ES3057685T3/es active Active
- 2017-04-28 SG SG11201809086YA patent/SG11201809086YA/en unknown
- 2017-04-28 PL PL17727094.9T patent/PL3448409T3/pl unknown
- 2017-04-28 AU AU2017258242A patent/AU2017258242B2/en not_active Expired - Fee Related
- 2017-04-28 BR BR112018071972-2A patent/BR112018071972A2/pt not_active IP Right Cessation
- 2017-04-28 JP JP2018556275A patent/JP2019514908A/ja not_active Ceased
- 2017-04-28 WO PCT/DK2017/050132 patent/WO2017186250A1/en not_active Ceased
- 2017-04-28 RU RU2018141326A patent/RU2740913C2/ru active
- 2017-04-28 EP EP17727094.9A patent/EP3448409B1/en active Active
- 2017-04-28 CA CA3022497A patent/CA3022497A1/en active Pending
- 2017-04-28 KR KR1020187033643A patent/KR102465341B1/ko active Active
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