JP2019509344A5 - - Google Patents

Info

Publication number

JP2019509344A5

JP2019509344A5 JP2019500035A JP2019500035A JP2019509344A5 JP 2019509344 A5 JP2019509344 A5 JP 2019509344A5 JP 2019500035 A JP2019500035 A JP 2019500035A JP 2019500035 A JP2019500035 A JP 2019500035A JP 2019509344 A5 JP2019509344 A5 JP 2019509344A5

Authority

JP

Japan

Prior art keywords

fatty acids

omega

lipid

triglyceride

fatty acid

Prior art date

2017-03-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 235000020660 omega-3 fatty acid Nutrition 0.000 claims 33
• 150000002632 lipids Chemical class 0.000 claims 22
• 235000014113 dietary fatty acids Nutrition 0.000 claims 19
• 239000000194 fatty acid Substances 0.000 claims 19
• 229930195729 fatty acid Natural products 0.000 claims 19
• 239000000203 mixture Substances 0.000 claims 18
• 229940012843 omega-3 fatty acid Drugs 0.000 claims 14
• 150000004665 fatty acids Chemical class 0.000 claims 11
• UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 11
• -1 DHA fatty acids Chemical class 0.000 claims 8
• CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 8
• 239000003921 oil Substances 0.000 claims 8
• 235000019198 oils Nutrition 0.000 claims 8
• 238000009472 formulation Methods 0.000 claims 7
• 150000003626 triacylglycerols Chemical class 0.000 claims 7
• 239000006014 omega-3 oil Substances 0.000 claims 6
• 229920000858 Cyclodextrin Polymers 0.000 claims 5
• 239000001116 FEMA 4028 Substances 0.000 claims 5
• WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 5
• 235000011175 beta-cyclodextrine Nutrition 0.000 claims 5
• 229960004853 betadex Drugs 0.000 claims 5
• 239000000843 powder Substances 0.000 claims 5
• 150000001875 compounds Chemical class 0.000 claims 4
• 239000004094 surface-active agent Substances 0.000 claims 4
• 239000000470 constituent Substances 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 3
• 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 2
• 241000238366 Cephalopoda Species 0.000 claims 2
• 241000195493 Cryptophyta Species 0.000 claims 2
• 239000007864 aqueous solution Substances 0.000 claims 2
• 229920002301 cellulose acetate Polymers 0.000 claims 2
• 229940081734 cellulose acetate phthalate Drugs 0.000 claims 2
• 235000019961 diglycerides of fatty acid Nutrition 0.000 claims 2
• 235000021323 fish oil Nutrition 0.000 claims 2
• 229940117841 methacrylic acid copolymer Drugs 0.000 claims 2
• 229920003145 methacrylic acid copolymer Polymers 0.000 claims 2
• 239000001788 mono and diglycerides of fatty acids Substances 0.000 claims 2
• 229940100467 polyvinyl acetate phthalate Drugs 0.000 claims 2
• IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 1
• IYKJEILNJZQJPU-UHFFFAOYSA-N acetic acid;butanedioic acid Chemical compound CC(O)=O.OC(=O)CCC(O)=O IYKJEILNJZQJPU-UHFFFAOYSA-N 0.000 claims 1
• ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 238000005469 granulation Methods 0.000 claims 1
• 230000003179 granulation Effects 0.000 claims 1
• 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 1
• 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 1
• 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 1
• IWVKTOUOPHGZRX-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.COC(=O)C(C)=C IWVKTOUOPHGZRX-UHFFFAOYSA-N 0.000 claims 1
• IQSHMXAZFHORGY-UHFFFAOYSA-N methyl prop-2-enoate;2-methylprop-2-enoic acid Chemical compound COC(=O)C=C.CC(=C)C(O)=O IQSHMXAZFHORGY-UHFFFAOYSA-N 0.000 claims 1
• 229920002689 polyvinyl acetate Polymers 0.000 claims 1
• 239000011118 polyvinyl acetate Substances 0.000 claims 1
• 229920002744 polyvinyl acetate phthalate Polymers 0.000 claims 1
• 239000000661 sodium alginate Substances 0.000 claims 1
• 235000010413 sodium alginate Nutrition 0.000 claims 1
• 229940005550 sodium alginate Drugs 0.000 claims 1
• 239000000243 solution Substances 0.000 claims 1
• 239000007921 spray Substances 0.000 claims 1
• 125000005591 trimellitate group Chemical group 0.000 claims 1
• 235000021122 unsaturated fatty acids Nutrition 0.000 claims 1
• 150000004670 unsaturated fatty acids Chemical group 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1