JP2019505164A5 - - Google Patents

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Publication number
JP2019505164A5
JP2019505164A5 JP2018522671A JP2018522671A JP2019505164A5 JP 2019505164 A5 JP2019505164 A5 JP 2019505164A5 JP 2018522671 A JP2018522671 A JP 2018522671A JP 2018522671 A JP2018522671 A JP 2018522671A JP 2019505164 A5 JP2019505164 A5 JP 2019505164A5
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JP
Japan
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protein
host cell
fucose
culture
fucose source
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JP2018522671A
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English (en)
Japanese (ja)
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JP2019505164A (ja
JP6983772B2 (ja
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Priority claimed from PCT/US2016/059922 external-priority patent/WO2017079165A1/en
Publication of JP2019505164A publication Critical patent/JP2019505164A/ja
Publication of JP2019505164A5 publication Critical patent/JP2019505164A5/ja
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JP2018522671A 2015-11-02 2016-11-01 タンパク質のフコシル化及び脱フコシル化形態の作製方法 Active JP6983772B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562249828P 2015-11-02 2015-11-02
US62/249,828 2015-11-02
US201662338280P 2016-05-18 2016-05-18
US62/338,280 2016-05-18
PCT/US2016/059922 WO2017079165A1 (en) 2015-11-02 2016-11-01 Methods of making fucosylated and afucosylated forms of a protein

Publications (3)

Publication Number Publication Date
JP2019505164A JP2019505164A (ja) 2019-02-28
JP2019505164A5 true JP2019505164A5 (https=) 2019-12-12
JP6983772B2 JP6983772B2 (ja) 2021-12-17

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ID=57326491

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018522671A Active JP6983772B2 (ja) 2015-11-02 2016-11-01 タンパク質のフコシル化及び脱フコシル化形態の作製方法

Country Status (14)

Country Link
US (4) US10975168B2 (https=)
EP (2) EP3371206B1 (https=)
JP (1) JP6983772B2 (https=)
KR (2) KR102793554B1 (https=)
CN (2) CN116731147A (https=)
AU (2) AU2016350732A1 (https=)
BR (1) BR112018007356A2 (https=)
CA (1) CA2999047A1 (https=)
ES (1) ES2875274T3 (https=)
IL (1) IL258161B2 (https=)
MX (1) MX2018004831A (https=)
PL (1) PL3371206T3 (https=)
SG (2) SG11201802773RA (https=)
WO (1) WO2017079165A1 (https=)

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ES2875274T3 (es) 2015-11-02 2021-11-10 Hoffmann La Roche Procedimientos de preparación de formas fucosiladas y afucosiladas de una proteína
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US12325737B2 (en) 2018-03-26 2025-06-10 Amgen Inc. Total afucosylated glycoforms of antibodies produced in cell culture
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CA3110530A1 (en) 2018-09-11 2020-03-19 Amgen Inc. Methods of modulating antibody-dependent cell-mediated cytotoxicity
HU231514B1 (hu) 2018-11-07 2024-07-28 Richter Gedeon Nyrt. Sejttenyészetben előállított rekombináns glikoprotein glikozilációs mintázatának megváltoztatására szolgáló módszer
DK3941946T3 (da) 2019-03-20 2025-03-24 Univ California Claudin-6-antistoffer og lægemiddelkonjugater
US20220177583A1 (en) 2019-03-20 2022-06-09 The Regents Of The University Of California Claudin-6 bispecific antibodies
MX2021013628A (es) 2019-05-06 2022-03-07 Amgen Inc Modulación de las funciones efectoras de anticuerpos.
BR112022005583A2 (pt) * 2019-09-26 2022-09-20 Amgen Inc Métodos para a produção de composições de anticorpos
WO2021072244A1 (en) * 2019-10-11 2021-04-15 Beth Israel Deaconess Medical Center, Inc. Anti-tn antibodies and uses thereof
KR20230033719A (ko) * 2020-07-02 2023-03-08 기가젠, 인코포레이티드 항-ctla-4 결합 단백질 및 이의 사용 방법
EP4352094A1 (en) 2021-06-07 2024-04-17 Amgen Inc. Using fucosidase to control afucosylation level of glycosylated proteins
KR20240045239A (ko) * 2021-08-06 2024-04-05 안야디, 엘엘씨 개인 맞춤형 암 면역치료제 제조방법
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