JP2019503493A5 - - Google Patents

Download PDF

Info

Publication number
JP2019503493A5
JP2019503493A5 JP2018547858A JP2018547858A JP2019503493A5 JP 2019503493 A5 JP2019503493 A5 JP 2019503493A5 JP 2018547858 A JP2018547858 A JP 2018547858A JP 2018547858 A JP2018547858 A JP 2018547858A JP 2019503493 A5 JP2019503493 A5 JP 2019503493A5
Authority
JP
Japan
Prior art keywords
fluid channel
imaging
microfluidic device
separated
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018547858A
Other languages
English (en)
Japanese (ja)
Other versions
JP6906542B2 (ja
JP2019503493A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/064013 external-priority patent/WO2017095813A1/en
Publication of JP2019503493A publication Critical patent/JP2019503493A/ja
Publication of JP2019503493A5 publication Critical patent/JP2019503493A5/ja
Priority to JP2021107723A priority Critical patent/JP7323576B2/ja
Application granted granted Critical
Publication of JP6906542B2 publication Critical patent/JP6906542B2/ja
Priority to JP2023122384A priority patent/JP7781114B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018547858A 2015-11-30 2016-11-29 試料の特性評価のためのデバイス及び方法 Active JP6906542B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021107723A JP7323576B2 (ja) 2015-11-30 2021-06-29 試料の特性評価のためのデバイス及び方法
JP2023122384A JP7781114B2 (ja) 2015-11-30 2023-07-27 試料の特性評価のためのデバイス及び方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562260944P 2015-11-30 2015-11-30
US62/260,944 2015-11-30
US201662338074P 2016-05-18 2016-05-18
US62/338,074 2016-05-18
PCT/US2016/064013 WO2017095813A1 (en) 2015-11-30 2016-11-29 Devices and methods for sample characterization

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021107723A Division JP7323576B2 (ja) 2015-11-30 2021-06-29 試料の特性評価のためのデバイス及び方法

Publications (3)

Publication Number Publication Date
JP2019503493A JP2019503493A (ja) 2019-02-07
JP2019503493A5 true JP2019503493A5 (https=) 2020-01-16
JP6906542B2 JP6906542B2 (ja) 2021-07-21

Family

ID=58798061

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018547858A Active JP6906542B2 (ja) 2015-11-30 2016-11-29 試料の特性評価のためのデバイス及び方法
JP2021107723A Active JP7323576B2 (ja) 2015-11-30 2021-06-29 試料の特性評価のためのデバイス及び方法
JP2023122384A Active JP7781114B2 (ja) 2015-11-30 2023-07-27 試料の特性評価のためのデバイス及び方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021107723A Active JP7323576B2 (ja) 2015-11-30 2021-06-29 試料の特性評価のためのデバイス及び方法
JP2023122384A Active JP7781114B2 (ja) 2015-11-30 2023-07-27 試料の特性評価のためのデバイス及び方法

Country Status (9)

Country Link
US (6) US20170176386A1 (https=)
EP (3) EP3957986B1 (https=)
JP (3) JP6906542B2 (https=)
KR (1) KR102868202B1 (https=)
CN (2) CN108603828A (https=)
AU (2) AU2016365121B2 (https=)
DE (1) DE202016008838U1 (https=)
DK (1) DK3384274T3 (https=)
WO (1) WO2017095813A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017095813A1 (en) 2015-11-30 2017-06-08 Intabio, Inc. Devices and methods for sample characterization
EP3398201A4 (en) * 2015-12-31 2019-11-06 University of Notre Dame du Lac ESI-MS VIA AN ELECTRO-KINETICALLY PUMPED INTERFACE
AU2017213725B2 (en) 2016-02-01 2021-12-23 Li-Cor, Inc. Capillary electrophoresis inkjet dispensing
CN109564187A (zh) * 2016-08-08 2019-04-02 利康公司 用于微流体直接印迹的多鞘流和芯片上的终端电极
US11241689B2 (en) * 2016-08-08 2022-02-08 Li-Cor, Inc. Microchip electrophoresis inkjet dispensing
KR102691269B1 (ko) * 2018-01-29 2024-08-05 인타바이오 엘엘씨 샘플 특성화를 위한 장치, 방법 및 키트
KR102790154B1 (ko) * 2018-05-31 2025-04-04 인타바이오 엘엘씨 질량분광법과 인터페이스로 연결된 미소유체 시스템을 위한 소프트웨어
US12038408B2 (en) 2018-10-03 2024-07-16 The Regents Of The University Of Michigan Integrated micro-photoionization detector with an ultrathin ultraviolet transmission window
MY204150A (en) * 2019-01-25 2024-08-09 Regeneron Pharma Online chromatography and electrospray ionization mass spectrometer
US12594557B2 (en) 2019-08-12 2026-04-07 Intabio, Llc Isoelectric focusing devices and fixtures
US11285484B2 (en) 2019-08-12 2022-03-29 Intabio, Llc Multichannel isoelectric focusing devices and high voltage power supplies
KR20220073837A (ko) * 2019-10-09 2022-06-03 프로틴심플 순차적 pH 조절을 갖는 단일 채널 자유 유동 전기영동 방법
CA3162469A1 (en) * 2019-11-25 2021-06-03 Intabio, Llc Software for microfluidic systems interfacing with mass spectrometry
JP7759895B2 (ja) * 2020-04-28 2025-10-24 インタバイオ, エルエルシー サンプル霧化のためのガスチャネルを伴うマイクロ流体デバイス
GB202103194D0 (en) * 2020-06-23 2021-04-21 Micromass Ltd Nebuliser outlet
IL303698A (en) * 2020-12-15 2023-08-01 Proteas Bioanalytics Inc Mass spectrometry sample processing methods, chromatography devices, and data analysis techniques for biomarker analysis
CN113838738A (zh) * 2021-09-14 2021-12-24 清华大学深圳国际研究生院 一种质谱联用多通道电喷雾微流控芯片离子源
US20230175951A1 (en) * 2021-12-08 2023-06-08 Georgia Tech Research Corporation Systems and Methods for Live Cell Imaging
KR20250116014A (ko) 2022-10-28 2025-07-31 리엑스유니버시테이트 그로닝겐 나노기공-기반 단백질 분석
WO2024242919A1 (en) * 2023-05-24 2024-11-28 Intabio, Llc Isoelectric focusing devices and methods

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395502A (en) 1988-11-14 1995-03-07 Anthony R. Torres Apparatus for performing and universally detecting capillary isoelectric focusing without mobilization using concentration gradient imaging systems
DE69117875T2 (de) 1990-11-08 1996-07-25 Alcatel Fibres Optiques Herstellungsverfahren von Multisteckerstiften mit einer Reihe von Kanälen mit parallelen Achsen und so hergestellter Multisteckerstift
US5110434A (en) 1990-12-20 1992-05-05 Bio-Rad Laboratories, Inc. Use of zwitterions to mobilize isoelectrically focused ampholyte zones
US5259939A (en) 1991-08-30 1993-11-09 Beckman Instruments, Inc. Capillary electrophoresis buffer
US5784154A (en) 1992-01-13 1998-07-21 Anthony R. Torres Electrophoresis separation in a capillary passage
US5423964A (en) 1993-08-02 1995-06-13 Battelle Memorial Institute Combined electrophoresis-electrospray interface and method
US6001229A (en) 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
GB9509905D0 (en) 1995-05-11 1995-07-12 Watson Arthur H Fast sample device for capillary isoelectric focusing
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
CN1329729C (zh) 1996-06-28 2007-08-01 卡钳生命科学股份有限公司 微流体系统
US5779868A (en) 1996-06-28 1998-07-14 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
US5800690A (en) 1996-07-03 1998-09-01 Caliper Technologies Corporation Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces
US6110343A (en) 1996-10-04 2000-08-29 Lockheed Martin Energy Research Corporation Material transport method and apparatus
US5876675A (en) 1997-08-05 1999-03-02 Caliper Technologies Corp. Microfluidic devices and systems
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
EP1044370B1 (en) 1997-12-30 2017-08-23 Caliper Life Sciences, Inc. Software for the display of chromatographic separation data
US6167910B1 (en) 1998-01-20 2001-01-02 Caliper Technologies Corp. Multi-layer microfluidic devices
JP3887963B2 (ja) 1998-08-07 2007-02-28 株式会社島津製作所 等電点電気泳動装置
CN100525876C (zh) 1998-09-17 2009-08-12 阿德文生物系统公司 产生液体电喷射的方法
US6149787A (en) 1998-10-14 2000-11-21 Caliper Technologies Corp. External material accession systems and methods
JP2000162184A (ja) 1998-11-30 2000-06-16 Hitachi Ltd 小型電気泳動装置及びこれを用いた質量分析装置
AU2854400A (en) 1999-01-22 2000-08-07 Lord Corporation Autodepositable adhesive
ATE556149T1 (de) 1999-02-23 2012-05-15 Caliper Life Sciences Inc Manipulation von mikropartikeln in mikrofluidischen systemen
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
US7329388B2 (en) 1999-11-08 2008-02-12 Princeton Biochemicals, Inc. Electrophoresis apparatus having staggered passage configuration
US6974527B2 (en) 2000-06-06 2005-12-13 Spectrumedix Llc Multidimensional separations employing an array of electrophoresis channels
US20020079220A1 (en) 2000-11-09 2002-06-27 Pawliszyn Janusz B. Micromachining using printing technology
US20050189225A1 (en) 2001-02-09 2005-09-01 Shaorong Liu Apparatus and method for small-volume fluid manipulation and transportation
AU2002256998A1 (en) 2001-02-09 2002-09-19 Microchem Solutions Apparatus and method for small-volume fluid manipulation and transportation
US20020139751A1 (en) * 2001-02-20 2002-10-03 Sheng Zhang Microchip electrospray device and column with affinity adsorbents and use of the same
US6974526B2 (en) * 2001-05-01 2005-12-13 Calibrant Biosystems, Inc. Plastic microfluidics enabling two-dimensional protein separations in proteome analysis
US7601251B2 (en) 2001-05-10 2009-10-13 Life Technologies Corporation Methods and apparatus for low resistance electrophoresis of prior-cast, hydratable separation media
EP1395939A4 (en) 2001-05-24 2006-06-07 New Objective Inc METHOD AND APPARATUS FOR ELECTRO-WAVING REGULATED BY FEEDBACK
EP1493487A1 (de) 2001-06-28 2005-01-05 Agilent Technologies, Inc. Mikrofluid-System mit ESI-Reststromregelung
CN1549924A (zh) 2001-07-16 2004-11-24 �����ʸ���˹�ع�˾ 通过等电点分析生物分子的缓冲液的阵列
US6803568B2 (en) * 2001-09-19 2004-10-12 Predicant Biosciences, Inc. Multi-channel microfluidic chip for electrospray ionization
JP2005509872A (ja) * 2001-10-19 2005-04-14 ウエスト バージニア ユニバーシティ リサーチ コーポレーション プロテオーム解析のための微小流体システム
US6831274B2 (en) 2002-03-05 2004-12-14 Battelle Memorial Institute Method and apparatus for multispray emitter for mass spectrometry
JP2004069430A (ja) * 2002-08-05 2004-03-04 Mitsubishi Kagaku Iatron Inc 電気泳動用チップ、その製造方法、及び物質の分離方法
US7381317B2 (en) 2002-08-12 2008-06-03 Beckman Coulter, Inc. Methods and compositions for capillary electrophoresis (CE)
US20040112751A1 (en) * 2002-08-26 2004-06-17 Jongyoon Han Multidimensional electrophoresis and methods of making and using thereof
EP1548429A4 (en) * 2002-09-05 2009-06-17 Katayanagi Inst PROCESS FOR SEPARATING SUBSTANCES
GB0226160D0 (en) * 2002-11-08 2002-12-18 Diagnoswiss Sa Apparatus for dispensing a sample in electrospray mass spectrometers
US8080145B2 (en) 2003-01-15 2011-12-20 Protasis Corporation Method and apparatus determining the isoelectric point of charged analyte
WO2004077017A2 (en) * 2003-02-21 2004-09-10 West Virginia University Research Corporation Apparatus and method for on-chip concentration using a microfluidic device with an integrated ultrafiltration membrane structure
US7655477B1 (en) 2003-02-26 2010-02-02 Science Applications International Corporation System and method for the separation of analytes
JP3969654B2 (ja) 2003-03-07 2007-09-05 インターナショナル・ビジネス・マシーンズ・コーポレーション Soapメッセージ作成方法並びに処理方法、情報処理方法、情報処理装置及びプログラム
US7425700B2 (en) 2003-05-22 2008-09-16 Stults John T Systems and methods for discovery and analysis of markers
US20050072915A1 (en) 2003-10-07 2005-04-07 Biospect Inc. Methods and apparatus for self-optimization of electrospray ionization devices
US8267914B1 (en) 2003-10-16 2012-09-18 University Of Notre Dame Du Lac Method and apparatus for AC electrospray
CN1616958A (zh) * 2003-11-11 2005-05-18 中国科学院大连化学物理研究所 一种基于微流控芯片的细胞定性分析方法
US7022214B2 (en) 2004-01-21 2006-04-04 Bio-Rad Laboratories, Inc. Carrier ampholytes of high pH range
US20060060769A1 (en) 2004-09-21 2006-03-23 Predicant Biosciences, Inc. Electrospray apparatus with an integrated electrode
JP2006220551A (ja) * 2005-02-10 2006-08-24 Toray Ind Inc マイクロチップ
EP1872139A2 (en) 2005-04-09 2008-01-02 Cell Biosciences, Inc. Automated micro-volume assay system
DE602005026500D1 (de) 2005-07-15 2011-04-07 Agilent Technologies Inc Vorrichtung zur Handhaben von mikrofluidischen Vorrichtungen mit einer Klemmeinrichtung
US7329865B2 (en) 2005-11-14 2008-02-12 Agilent Technologies, Inc. Mass spectrometry system and method with window assembly
JP4900245B2 (ja) 2005-11-14 2012-03-21 日本電気株式会社 マイクロチップおよびその使用方法、ならびに質量分析システム
US7339166B2 (en) 2006-02-24 2008-03-04 Battelle Memorial Institute Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure
US7495210B2 (en) 2006-05-04 2009-02-24 Agilent Technologies, Inc. Micro fluidic gas assisted ionization device and method
US20080035484A1 (en) * 2006-07-10 2008-02-14 Jiaqi Wu Method and apparatus for precise selection and extraction of a focused component in isoelectric focusing performed in micro-channels
US8841116B2 (en) 2006-10-25 2014-09-23 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated DNA analysis system using same
US20080318334A1 (en) * 2007-06-20 2008-12-25 Robotti Karla M Microfluidic devices comprising fluid flow paths having a monolithic chromatographic material
US8329016B1 (en) 2007-07-30 2012-12-11 Sandia Corporation Microfluidic device having an immobilized pH gradient and PAGE gels for protein separation and analysis
US10107782B2 (en) * 2008-01-25 2018-10-23 ProteinSimple Method to perform limited two dimensional separation of proteins and other biologicals
US8173080B2 (en) 2008-02-14 2012-05-08 Illumina, Inc. Flow cells and manifolds having an electroosmotic pump
WO2009109037A1 (en) 2008-03-07 2009-09-11 The University Of British Colu Self-contained capillary electrophoresis system for interfacing with mass spectrometry
FR2934179B1 (fr) * 2008-07-24 2010-09-17 Commissariat Energie Atomique Laboratoire sur puce comprenant un reseau micro-fluidique et un nez d'electronebulisation coplanaires.
CN101344518B (zh) * 2008-08-15 2012-04-11 东南大学 微纳生物粒子的多模式集成化介电表征装置及方法
CN201247242Y (zh) * 2008-08-15 2009-05-27 东南大学 微纳生物粒子介电表征装置
JP5164163B2 (ja) * 2008-10-20 2013-03-13 独立行政法人産業技術総合研究所 等電点マーカー蛋白質
US7939798B2 (en) * 2009-01-30 2011-05-10 Agilent Technologies, Inc. Tandem ionizer ion source for mass spectrometer and method of use
GB0905575D0 (en) * 2009-03-31 2009-05-13 Stfc Science & Technology Electrospinning nozzle
CN101692048B (zh) * 2009-10-27 2012-04-25 浙江大学 毛细管电泳分离和化学发光检测的微芯片分析系统
US20110243813A1 (en) * 2010-03-30 2011-10-06 Jackinsky Steve W Diagnostic card with micro-fluidic channels and method of construction thereof
US20160084805A1 (en) 2010-09-23 2016-03-24 Battelle Memorial Institute System and method of preconcentrating analytes in a microfluidic device
WO2012125318A2 (en) 2011-03-11 2012-09-20 The University Of North Carolina At Chapel Hill Microchips with integrated multiple electrospray ionization emitters and related methods, systems and devices
US9234880B2 (en) 2011-06-03 2016-01-12 University Of Washington Through Its Center For Commercialization Sheath-flow electrospray interface
GB201112726D0 (en) * 2011-07-22 2011-09-07 Molecular Vision Ltd An optical device
CN103998394B (zh) * 2011-08-01 2016-08-17 德诺弗科学公司 细胞捕获系统和使用方法
JP6339024B2 (ja) 2012-02-10 2018-06-06 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill 流体ナノファンネルを有する装置、関連する方法、製造及び解析システム
WO2013155634A1 (en) 2012-04-19 2013-10-24 Jiaqi Wu Dual wavelength isoelectric focusing for determining drug load in antibody drug conjugates
US9159537B2 (en) * 2012-05-03 2015-10-13 University Of Notre Dame Du Lac Method for analyzing sample components
US9500621B2 (en) 2012-06-04 2016-11-22 Beckman Coulter, Inc. Leakage current sense circuit for error detection in an improved capillary electrophoresis-electrospray ionization-mass spectrometry system
EP2864764B1 (en) 2012-06-20 2018-03-07 The University of North Carolina At Chapel Hill Integrated sample processing for electrospray ionization devices
EP2971136B1 (en) 2013-03-15 2019-11-27 Lariat Biosciences, Inc. Microfluidic methods for manipulating dna
HK1226142A1 (zh) * 2013-08-29 2017-09-22 University Of Notre Dame Du Lac 高灵敏度电喷射接口
US9766206B2 (en) 2013-09-27 2017-09-19 ProteinSimple Apparatus, systems, and methods for capillary electrophoresis
US20150093757A1 (en) 2013-09-27 2015-04-02 Protein Simple Methods. apparatus and systems for detection of total protein using capillary electrophoresis
US10031104B2 (en) 2014-06-13 2018-07-24 Yes Way Intellectual Holdings, Llc Mobile micro-lab for chemical analysis of fluids
EP3226993B1 (en) 2014-12-05 2024-01-24 Advanced Electrophoresis Solutions Ltd Apparatus and method for separating molecules
US9606082B2 (en) 2015-05-11 2017-03-28 The University Of North Carolina At Chapel Hill Pressure driven microfluidic injection for chemical separations
US9255905B1 (en) 2015-05-11 2016-02-09 The University Of North Carolina At Chapel Hill Pressure driven microfluidic injection for chemical separations
EP3885368A1 (en) 2015-05-12 2021-09-29 Regeneron Pharmaceuticals, Inc. Multimeric protein purity determination
JP6864634B2 (ja) 2015-05-20 2021-04-28 プロテインシンプル 検体の電気泳動分離および分析のためのシステムおよび方法
CN106374981B (zh) 2015-07-20 2021-01-08 索尼公司 无线通信系统中的电子设备和无线通信方法
US9728387B2 (en) 2015-10-20 2017-08-08 The University Of North Carolina At Chapel Hill Solid phase extraction with capillary electrophoresis
WO2017095813A1 (en) 2015-11-30 2017-06-08 Intabio, Inc. Devices and methods for sample characterization
WO2017123970A1 (en) 2016-01-13 2017-07-20 ProteinSimple Systems and methods for capillary electrophoresis, isoelectric point, and molecular weight analysis
CN109564187A (zh) 2016-08-08 2019-04-02 利康公司 用于微流体直接印迹的多鞘流和芯片上的终端电极
US11241689B2 (en) 2016-08-08 2022-02-08 Li-Cor, Inc. Microchip electrophoresis inkjet dispensing
JP2019536985A (ja) 2016-09-26 2019-12-19 ユニヴァーシティー オブ ノートル ダム デュ ラック キャピラリーゾーン電気泳動/エレクトロスプレーデバイスにおける電流逆転の緩和のための方法及び装置
EP3602026B1 (en) 2017-03-30 2025-10-08 908 Devices Inc. Microfluidic analysis of biological samples
KR102691269B1 (ko) 2018-01-29 2024-08-05 인타바이오 엘엘씨 샘플 특성화를 위한 장치, 방법 및 키트
KR102790154B1 (ko) 2018-05-31 2025-04-04 인타바이오 엘엘씨 질량분광법과 인터페이스로 연결된 미소유체 시스템을 위한 소프트웨어
US11285484B2 (en) 2019-08-12 2022-03-29 Intabio, Llc Multichannel isoelectric focusing devices and high voltage power supplies

Similar Documents

Publication Publication Date Title
JP2019503493A5 (https=)
JP7781114B2 (ja) 試料の特性評価のためのデバイス及び方法
Strausbauch et al. Mechanism of peptide separations by solid phase extraction capillary electrophoresis at low pH
KR102790154B1 (ko) 질량분광법과 인터페이스로 연결된 미소유체 시스템을 위한 소프트웨어
US9728387B2 (en) Solid phase extraction with capillary electrophoresis
Janini et al. A sheathless nanoflow electrospray interface for on-line capillary electrophoresis mass spectrometry
Chen et al. Capillary zone electrophoresis–mass spectrometry with microliter-scale loading capacity, 140 min separation window and high peak capacity for bottom-up proteomics
JP6422131B2 (ja) 分離分析用キャピラリーデバイス、分離分析用マイクロ流体チップ、タンパク質又はペプチド分析方法、電気泳動装置、及び分離分析用マイクロ流体チップ電気泳動装置
Janini et al. On-column sample enrichment for capillary electrophoresis sheathless electrospray ionization mass spectrometry: evaluation for peptide analysis and protein identification
Medina-Casanellas et al. Low-picomolar analysis of peptides by on-line coupling of fritless solid-phase extraction to sheathless capillary electrophoresis-mass spectrometry
Gorbatsova et al. Electrowetting-on-dielectric actuation of droplets with capillary electrophoretic zones for off-line mass spectrometric analysis
Nordman et al. Interfacing microchip isoelectric focusing with on-chip electrospray ionization mass spectrometry
Rollman et al. Ultrafast capillary electrophoresis/mass spectrometry of controlled substances with optical isomer separation in about a minute
Moini et al. Portable, battery operated capillary electrophoresis with optical isomer resolution integrated with ionization source for mass spectrometry
US10888860B2 (en) Sample transfer device and method for sample transfer
Hezinová et al. Simultaneous analysis of cocaine and its metabolites in urine by capillary electrophoresis–electrospray mass spectrometry using a pressurized liquid junction nanoflow interface
Smejkal Microfluidics in bioanalytical instrumentation
Neusüß et al. Coupling of capillary electromigration techniques to mass spectrometry
CN106855541A (zh) 一种基于微流控芯片与纳升电喷雾离子迁移谱的检测装置
Deng et al. Open channel-based microchip electrophoresis interfaced with mass spectrometry via electrostatic spray ionization
Feng et al. Protein identification from two-dimensional gel electrophoresis by connecting ZipTip with a home-assembled nanoflow system
Zhang et al. Interfacing DART to Extend Analytical Capabilities
Koval et al. Coupling of large bore capillary isotachophoresis with MS-new analytical possibilities in analysis of complex matrix
Peterson Analysis of Clinically Important Compounds Using Electrophoretic Separation Techniques Coupled to Time-of-Flight Mass Spectrometry
RU2017145695A (ru) Хроматографический способ идентификации и измерения массовой концентрации компонентов смеси неизвестного состава по временам удерживания