JP2019503348A5 - - Google Patents
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- Publication number
- JP2019503348A5 JP2019503348A5 JP2018530797A JP2018530797A JP2019503348A5 JP 2019503348 A5 JP2019503348 A5 JP 2019503348A5 JP 2018530797 A JP2018530797 A JP 2018530797A JP 2018530797 A JP2018530797 A JP 2018530797A JP 2019503348 A5 JP2019503348 A5 JP 2019503348A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- amino acid
- molecule
- kda
- acid residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562270447P | 2015-12-21 | 2015-12-21 | |
| US62/270,447 | 2015-12-21 | ||
| PCT/US2016/067042 WO2017112528A2 (en) | 2015-12-21 | 2016-12-15 | Interleukin-15 compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019503348A JP2019503348A (ja) | 2019-02-07 |
| JP2019503348A5 true JP2019503348A5 (https=) | 2020-01-30 |
Family
ID=59091160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530797A Withdrawn JP2019503348A (ja) | 2015-12-21 | 2016-12-15 | インターロイキン−１５組成物及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180360977A1 (https=) |
| EP (1) | EP3393486A4 (https=) |
| JP (1) | JP2019503348A (https=) |
| KR (1) | KR20180089516A (https=) |
| CN (1) | CN108472324A (https=) |
| AU (1) | AU2016378387A1 (https=) |
| BR (1) | BR112018012262A2 (https=) |
| CA (1) | CA3007819A1 (https=) |
| IL (1) | IL259919A (https=) |
| MX (1) | MX2018007304A (https=) |
| WO (1) | WO2017112528A2 (https=) |
| ZA (1) | ZA201803875B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019019998A1 (zh) * | 2017-07-25 | 2019-01-31 | 江苏恒瑞医药股份有限公司 | 一种il-15蛋白复合物药物组合物及其用途 |
| CN112004547A (zh) | 2018-02-26 | 2020-11-27 | 新索思股份有限公司 | Il-15缀合物及其用途 |
| WO2019245817A1 (en) | 2018-06-19 | 2019-12-26 | Armo Biosciences, Inc. | Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy |
| WO2020097556A1 (en) * | 2018-11-09 | 2020-05-14 | Nektar Therapeutics | Long-acting interleukin-15 receptor agonist in combination with another pharmacologically active agent |
| CN114126638A (zh) * | 2019-04-26 | 2022-03-01 | 普罗林科斯有限责任公司 | 缓慢释放的细胞因子偶联物 |
| IL288210B2 (en) | 2019-05-20 | 2026-03-01 | Cytune Pharma | Dosing regimens of IL-2/IL-15 beta-gamma receptor agonists for the treatment of cancer or infectious diseases |
| JP2022544405A (ja) * | 2019-08-15 | 2022-10-18 | アイジーエム バイオサイエンシズ インコーポレイテッド | 免疫刺激性多量体型結合分子 |
| EP4017540A1 (en) * | 2019-08-23 | 2022-06-29 | Synthorx, Inc. | Il-15 conjugates and uses thereof |
| EP4232068A1 (en) | 2020-10-26 | 2023-08-30 | Cytune Pharma | IL-2/IL-15RBetaGamma AGONIST FOR TREATING NON-MELANOMA SKIN CANCER |
| WO2022090203A1 (en) | 2020-10-26 | 2022-05-05 | Cytune Pharma | IL-2/IL-15Rβү AGONIST FOR TREATING SQUAMOUS CELL CARCINOMA |
| CN117597355A (zh) | 2021-06-23 | 2024-02-23 | 赛腾制药 | 白细胞介素15变体 |
| KR20240043797A (ko) | 2021-08-13 | 2024-04-03 | 싸이튠 파마 | 암 치료용 IL-2/IL-15Rβγ 작용제와 항체-약물 접합체 조합 |
| CN118251495A (zh) * | 2021-11-26 | 2024-06-25 | 杰科（天津）生物医药有限公司 | 一种蛋白的生产方法及其应用 |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| CN117510828A (zh) * | 2022-07-28 | 2024-02-06 | 厦门赛诺邦格生物科技股份有限公司 | 一种含氨基酸残基的三臂聚乙二醇衍生物 |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2367027T3 (es) * | 2004-02-27 | 2011-10-27 | Inserm (Institut National De La Santé Et De La Recherche Medicale) | Sitio de unión de la il-15 para il-15ralfa y mutantes específicos de il-15 que tienen actividad agonista/antagonista. |
| TW200613552A (en) * | 2004-08-11 | 2006-05-01 | Hoffmann La Roche | Mutant interleukin-15 polypeptides |
| JP2008515896A (ja) * | 2004-10-05 | 2008-05-15 | オクスナー クリニック ファウンデーション | Ｉｌ−１５によるｂ細胞増殖の増強 |
| MA39711A (fr) * | 2014-04-03 | 2015-10-08 | Nektar Therapeutics | Conjugués d'une fraction d'il-15 et d'un polymère |
| WO2016060996A2 (en) * | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
-
2016
- 2016-12-15 MX MX2018007304A patent/MX2018007304A/es unknown
- 2016-12-15 WO PCT/US2016/067042 patent/WO2017112528A2/en not_active Ceased
- 2016-12-15 EP EP16879902.1A patent/EP3393486A4/en not_active Withdrawn
- 2016-12-15 BR BR112018012262A patent/BR112018012262A2/pt not_active Application Discontinuation
- 2016-12-15 AU AU2016378387A patent/AU2016378387A1/en not_active Abandoned
- 2016-12-15 CA CA3007819A patent/CA3007819A1/en not_active Abandoned
- 2016-12-15 JP JP2018530797A patent/JP2019503348A/ja not_active Withdrawn
- 2016-12-15 KR KR1020187020534A patent/KR20180089516A/ko not_active Withdrawn
- 2016-12-15 CN CN201680079249.3A patent/CN108472324A/zh active Pending
- 2016-12-15 US US16/060,389 patent/US20180360977A1/en not_active Abandoned
-
2018
- 2018-06-10 IL IL259919A patent/IL259919A/en unknown
- 2018-06-11 ZA ZA2018/03875A patent/ZA201803875B/en unknown
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