JP2019502719A5 - - Google Patents
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- Publication number
- JP2019502719A5 JP2019502719A5 JP2018536488A JP2018536488A JP2019502719A5 JP 2019502719 A5 JP2019502719 A5 JP 2019502719A5 JP 2018536488 A JP2018536488 A JP 2018536488A JP 2018536488 A JP2018536488 A JP 2018536488A JP 2019502719 A5 JP2019502719 A5 JP 2019502719A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nociception
- corneal nociception
- patient
- corneal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 11
- 230000020341 sensory perception of pain Effects 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 claims 2
- 108010003541 Platelet Activating Factor Proteins 0.000 claims 2
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 206010015958 Eye pain Diseases 0.000 claims 1
- 206010052143 Ocular discomfort Diseases 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 238000011109 contamination Methods 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 231100000397 ulcer Toxicity 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/006,085 US9827225B2 (en) | 2016-01-25 | 2016-01-25 | Use of prostacyclin antagonists for treating ocular surface nociception |
| US15/006,085 | 2016-01-25 | ||
| PCT/US2017/014677 WO2017132115A1 (en) | 2016-01-25 | 2017-01-24 | Use of prostacyclin antagonists for treating ocular surface nociception |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019502719A JP2019502719A (ja) | 2019-01-31 |
| JP2019502719A5 true JP2019502719A5 (https=) | 2020-02-27 |
| JP6752439B2 JP6752439B2 (ja) | 2020-09-09 |
Family
ID=59360031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536488A Active JP6752439B2 (ja) | 2016-01-25 | 2017-01-24 | 眼表面の侵害受容を処置するためのプロスタサイクリンアンタゴニストの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9827225B2 (https=) |
| EP (1) | EP3407975B1 (https=) |
| JP (1) | JP6752439B2 (https=) |
| KR (1) | KR20180104108A (https=) |
| CN (1) | CN108883307B (https=) |
| AU (1) | AU2017212343B2 (https=) |
| CA (1) | CA3012197A1 (https=) |
| ES (1) | ES2894916T3 (https=) |
| MX (1) | MX379497B (https=) |
| WO (1) | WO2017132115A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9827225B2 (en) * | 2016-01-25 | 2017-11-28 | Jenivision Inc. | Use of prostacyclin antagonists for treating ocular surface nociception |
| KR20210129677A (ko) * | 2019-02-15 | 2021-10-28 | 노파르티스 아게 | 안구 표면 통증의 치료 방법 |
| EP4288043A1 (en) * | 2021-02-05 | 2023-12-13 | Jenivision Inc. | Compositions and methods for periorbital administration of ep2 receptor agonists |
| WO2022197960A1 (en) * | 2021-03-18 | 2022-09-22 | Jenivision Inc. | Methods and compositions for treating eye diseases |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE153855T1 (de) * | 1992-10-13 | 1997-06-15 | Alcon Lab Inc | Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten |
| US6184242B1 (en) | 1997-09-04 | 2001-02-06 | Syntex Usa (Llc) | 2-(substituted-phenyl)amino-imidazoline derivatives |
| NZ331480A (en) * | 1997-09-04 | 2000-02-28 | F | 2-(Arylphenyl)amino-imidazoline derivatives and pharmaceutical compositions |
| PE20020146A1 (es) * | 2000-07-13 | 2002-03-31 | Upjohn Co | Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2) |
| SK7222003A3 (en) * | 2000-11-14 | 2004-05-04 | Hoffmann La Roche | Substituted 2-phenylaminoimidazoline phenyl ketone derivatives as IP antagonists |
| WO2004096213A1 (en) * | 2003-05-01 | 2004-11-11 | F. Hoffmann-La Roche Ag | Imidazolin-2-ylaminophenyl amides as ip antagonists |
| US9610990B2 (en) * | 2009-05-08 | 2017-04-04 | Titan Trailers Inc. | Apparatus and method for warming the floor of a trailer |
| CA2860392C (en) * | 2011-12-21 | 2016-08-30 | Allergan, Inc. | Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response |
| US9321745B2 (en) | 2013-03-12 | 2016-04-26 | Allergan, Inc. | Inhibition of neovascularization by inhibition of prostanoid IP receptors |
| US9820954B2 (en) | 2015-08-19 | 2017-11-21 | Jenivision Inc. | Quantitative peri-orbital application of ophthalmology drugs |
| US9827225B2 (en) | 2016-01-25 | 2017-11-28 | Jenivision Inc. | Use of prostacyclin antagonists for treating ocular surface nociception |
-
2016
- 2016-01-25 US US15/006,085 patent/US9827225B2/en active Active
-
2017
- 2017-01-24 KR KR1020187024480A patent/KR20180104108A/ko not_active Ceased
- 2017-01-24 JP JP2018536488A patent/JP6752439B2/ja active Active
- 2017-01-24 AU AU2017212343A patent/AU2017212343B2/en not_active Ceased
- 2017-01-24 CA CA3012197A patent/CA3012197A1/en active Pending
- 2017-01-24 ES ES17744748T patent/ES2894916T3/es active Active
- 2017-01-24 EP EP17744748.9A patent/EP3407975B1/en active Active
- 2017-01-24 WO PCT/US2017/014677 patent/WO2017132115A1/en not_active Ceased
- 2017-01-24 CN CN201780014505.5A patent/CN108883307B/zh active Active
- 2017-01-24 MX MX2018009125A patent/MX379497B/es unknown
- 2017-09-20 US US15/710,438 patent/US20180008578A1/en not_active Abandoned
-
2019
- 2019-09-05 US US16/562,063 patent/US20200345697A1/en not_active Abandoned
-
2021
- 2021-03-23 US US17/210,213 patent/US11857537B2/en active Active
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