JP2019502696A5 - - Google Patents

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Publication number
JP2019502696A5
JP2019502696A5 JP2018531529A JP2018531529A JP2019502696A5 JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5 JP 2018531529 A JP2018531529 A JP 2018531529A JP 2018531529 A JP2018531529 A JP 2018531529A JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5
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JP
Japan
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alkyl
halo
compound according
disorder
group
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JP2018531529A
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English (en)
Japanese (ja)
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JP7036725B2 (ja
JP2019502696A (ja
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Priority claimed from GBGB1522179.9A external-priority patent/GB201522179D0/en
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Publication of JP2019502696A5 publication Critical patent/JP2019502696A5/ja
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Publication of JP7036725B2 publication Critical patent/JP7036725B2/ja
Expired - Fee Related legal-status Critical Current
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JP2018531529A 2015-12-16 2016-12-16 Ｋｖ３チャネルのヒダントインモジュレーター Expired - Fee Related JP7036725B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1522179.9A GB201522179D0 (en) 2015-12-16 2015-12-16 Novel compounds
GB1522179.9 2015-12-16
PCT/GB2016/053958 WO2017103604A1 (en) 2015-12-16 2016-12-16 Hydantoin modulators of kv3 channels

Publications (3)

Publication Number Publication Date
JP2019502696A JP2019502696A (ja) 2019-01-31
JP2019502696A5 true JP2019502696A5 (https=) 2020-02-06
JP7036725B2 JP7036725B2 (ja) 2022-03-15

Family

ID=55274838

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018531529A Expired - Fee Related JP7036725B2 (ja) 2015-12-16 2016-12-16 Ｋｖ３チャネルのヒダントインモジュレーター

Country Status (7)

Country Link
US (1) US20200377485A1 (https=)
EP (1) EP3390394B1 (https=)
JP (1) JP7036725B2 (https=)
CN (1) CN108430995A (https=)
BR (1) BR112018012177A2 (https=)
GB (1) GB201522179D0 (https=)
WO (1) WO2017103604A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201521751D0 (en) 2015-12-10 2016-01-27 Autifony Therapeutics Ltd Novel uses
GB201613163D0 (en) 2016-07-29 2016-09-14 Autifony Therapeutics Ltd Novel compounds
EP3555073A1 (en) 2016-12-16 2019-10-23 Autifony Therapeutics Limited Hydantoin modulators of kv3 channels
KR102854594B1 (ko) 2018-10-16 2025-09-02 오티포니 세라피틱스 리미티드 신규한 화합물
US12358901B2 (en) 2018-10-16 2025-07-15 Autifony Therapeutics Limited KV3 modulators
AR116898A1 (es) 2018-10-30 2021-06-23 H Lundbeck As DERIVADOS DE ARILSULFONILPIRROLCARBOXAMIDA COMO ACTIVADORES DE CANALES DE POTASIO Kv3
JP2022529663A (ja) 2019-04-26 2022-06-23 ハー・ルンドベック・アクチエゼルスカベット Ｋｖ３カリウムチャネル活性化薬としてのアリールスルホニルチオフェンカルボキサミド及びアリールスルホニルフランカルボキサミド
WO2020216920A1 (en) 2019-04-26 2020-10-29 H. Lundbeck A/S N-((heteroaryl)methyl)-1-tosyl-1h-pyrazole-3-carboxamide derivatives as kv3 potassium channel activators for treating neurological and psychiatric disorders
BR112022013339A2 (pt) * 2020-02-06 2022-09-13 Autifony Therapeutics Ltd Moduladores de kv3
EP3901152A1 (en) * 2020-04-23 2021-10-27 F. Hoffmann-La Roche AG Kv3 enhancers for the treatment of cognitive disorders
KR20240046748A (ko) * 2021-08-10 2024-04-09 오티포니 세라피틱스 리미티드 칼륨 채널 조절제
WO2024121552A1 (en) 2022-12-06 2024-06-13 Autifony Therapeutics Limited Compounds for the treatment of centra nervous system disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6299383A (ja) * 1985-10-28 1987-05-08 Tokuyama Soda Co Ltd エ−テル化合物の製造方法
EP1534276B1 (en) 2002-09-05 2008-11-05 Medivir AB Non-nucleoside reverse transcriptase inhibitors
US20050080100A1 (en) 2003-10-09 2005-04-14 Pfizer Inc Pyridylamino compounds and methods of use thereof
EP1845087A1 (en) 2006-04-14 2007-10-17 Mutabilis SA Hydroxyphenyl derivatives and biological applications thereof
DK2563776T3 (en) 2010-04-27 2016-09-19 Calcimedica Inc Relations that modulate intracellular calcium
EA023768B1 (ru) * 2010-12-06 2016-07-29 Отифони Терапеутикс Лимитед ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ
US20120316182A1 (en) * 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
AR087309A1 (es) * 2011-07-27 2014-03-12 Glaxo Group Ltd Compuesto heterociclico de anillos condensados sustituido, composicion farmaceutica que lo comprende y su uso para la fabricacion de un medicamento para el tratamiento de enfermedades neurogenerativas y aterosclerosis
US9669030B2 (en) 2012-05-22 2017-06-06 Autifony Therapeutics Limited Hydantoin derivatives as Kv3 inhibitors
WO2013182851A1 (en) 2012-06-06 2013-12-12 Autifony Therapeutics Limited Prophylaxis or treatment of diseases where a modulator of kv3.3 channels is required
CN104471041A (zh) * 2012-06-06 2015-03-25 范德比尔特化学品有限责任公司 节油润滑油
WO2015031036A1 (en) * 2013-08-26 2015-03-05 Purdue Pharma L.P. Azaspiro[4.5] decane derivatives and use thereof

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