JP2019502696A5 - - Google Patents
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- JP2019502696A5 JP2019502696A5 JP2018531529A JP2018531529A JP2019502696A5 JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5 JP 2018531529 A JP2018531529 A JP 2018531529A JP 2018531529 A JP2018531529 A JP 2018531529A JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5
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- JP
- Japan
- Prior art keywords
- alkyl
- halo
- compound according
- disorder
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1522179.9 | 2015-12-16 | ||
| GBGB1522179.9A GB201522179D0 (en) | 2015-12-16 | 2015-12-16 | Novel compounds |
| PCT/GB2016/053958 WO2017103604A1 (en) | 2015-12-16 | 2016-12-16 | Hydantoin modulators of kv3 channels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019502696A JP2019502696A (ja) | 2019-01-31 |
| JP2019502696A5 true JP2019502696A5 (https=) | 2020-02-06 |
| JP7036725B2 JP7036725B2 (ja) | 2022-03-15 |
Family
ID=55274838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531529A Expired - Fee Related JP7036725B2 (ja) | 2015-12-16 | 2016-12-16 | Ｋｖ３チャネルのヒダントインモジュレーター |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20200377485A1 (https=) |
| EP (1) | EP3390394B1 (https=) |
| JP (1) | JP7036725B2 (https=) |
| CN (1) | CN108430995A (https=) |
| BR (1) | BR112018012177A2 (https=) |
| GB (1) | GB201522179D0 (https=) |
| WO (1) | WO2017103604A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201521751D0 (en) | 2015-12-10 | 2016-01-27 | Autifony Therapeutics Ltd | Novel uses |
| GB201613163D0 (en) | 2016-07-29 | 2016-09-14 | Autifony Therapeutics Ltd | Novel compounds |
| WO2018109484A1 (en) | 2016-12-16 | 2018-06-21 | Autifony Therapeutics Limited | Hydantoin modulators of kv3 channels |
| TWI827706B (zh) | 2018-10-16 | 2024-01-01 | 英商奧堤凡尼治療股份有限公司 | 新穎化合物 |
| US12358901B2 (en) | 2018-10-16 | 2025-07-15 | Autifony Therapeutics Limited | KV3 modulators |
| AR116898A1 (es) | 2018-10-30 | 2021-06-23 | H Lundbeck As | DERIVADOS DE ARILSULFONILPIRROLCARBOXAMIDA COMO ACTIVADORES DE CANALES DE POTASIO Kv3 |
| CN113692405A (zh) | 2019-04-26 | 2021-11-23 | H.隆德贝克有限公司 | 作为kv3钾通道激活剂的n-((杂芳基)甲基)-1-甲苯磺酰基-1h-吡唑-3-甲酰胺的衍生物用于治疗神经或精神障碍 |
| WO2020216919A1 (en) | 2019-04-26 | 2020-10-29 | H. Lundbeck A/S | ARYLSULFONYLTHIOPHENECARBOXAMIDES AND ARYLSULFONYLFURANCARBOXAMIDES AS Kν3 POTASSIUM CHANNEL ACTIVATORS |
| JP7522203B2 (ja) * | 2020-02-06 | 2024-07-24 | アウトイフオンイ トヘラペウトイクス リミテッド | Ｋｖ３モジュレーター |
| EP3901152A1 (en) * | 2020-04-23 | 2021-10-27 | F. Hoffmann-La Roche AG | Kv3 enhancers for the treatment of cognitive disorders |
| US20240327406A1 (en) | 2021-08-10 | 2024-10-03 | Autifony Therapeutics Limited | Potassium channel modulators |
| EP4630117A1 (en) | 2022-12-06 | 2025-10-15 | Autifony Therapeutics Limited | Compounds for the treatment of centra nervous system disorders |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6299383A (ja) * | 1985-10-28 | 1987-05-08 | Tokuyama Soda Co Ltd | エ−テル化合物の製造方法 |
| EP1534276B1 (en) | 2002-09-05 | 2008-11-05 | Medivir AB | Non-nucleoside reverse transcriptase inhibitors |
| US20050080100A1 (en) | 2003-10-09 | 2005-04-14 | Pfizer Inc | Pyridylamino compounds and methods of use thereof |
| EP1845087A1 (en) | 2006-04-14 | 2007-10-17 | Mutabilis SA | Hydroxyphenyl derivatives and biological applications thereof |
| JP6112486B2 (ja) | 2010-04-27 | 2017-04-12 | カルシメディカ，インク． | 細胞内カルシウムを調節する化合物 |
| EP2649066B1 (en) * | 2010-12-06 | 2015-10-21 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
| US20120316182A1 (en) * | 2011-06-10 | 2012-12-13 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| EP2736908A1 (en) | 2011-07-27 | 2014-06-04 | Glaxo Group Limited | Bicyclic pyrimidone compounds |
| EP2852588B8 (en) | 2012-05-22 | 2018-01-10 | Autifony Therapeutics Limited | Hydantoin derivatives as kv3 inhibitors |
| WO2013182851A1 (en) * | 2012-06-06 | 2013-12-12 | Autifony Therapeutics Limited | Prophylaxis or treatment of diseases where a modulator of kv3.3 channels is required |
| WO2013182581A1 (en) * | 2012-06-06 | 2013-12-12 | Evonik Oil Additives Gmbh | Fuel efficient lubricating oils |
| CN105612152A (zh) * | 2013-08-26 | 2016-05-25 | 普渡制药公司 | 氮杂螺[4.5]癸烷衍生物及其用途 |
-
2015
- 2015-12-16 GB GBGB1522179.9A patent/GB201522179D0/en not_active Ceased
-
2016
- 2016-12-16 EP EP16816359.0A patent/EP3390394B1/en not_active Not-in-force
- 2016-12-16 US US16/061,557 patent/US20200377485A1/en not_active Abandoned
- 2016-12-16 BR BR112018012177A patent/BR112018012177A2/pt not_active IP Right Cessation
- 2016-12-16 JP JP2018531529A patent/JP7036725B2/ja not_active Expired - Fee Related
- 2016-12-16 WO PCT/GB2016/053958 patent/WO2017103604A1/en not_active Ceased
- 2016-12-16 CN CN201680074553.9A patent/CN108430995A/zh active Pending
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