JP2016040288A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016040288A5 JP2016040288A5 JP2015196085A JP2015196085A JP2016040288A5 JP 2016040288 A5 JP2016040288 A5 JP 2016040288A5 JP 2015196085 A JP2015196085 A JP 2015196085A JP 2015196085 A JP2015196085 A JP 2015196085A JP 2016040288 A5 JP2016040288 A5 JP 2016040288A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- halogen
- alkyl
- hec1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31479810P | 2010-03-17 | 2010-03-17 | |
| US61/314,798 | 2010-03-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013500159A Division JP5825535B2 (ja) | 2010-03-17 | 2011-03-15 | Ｈｅｃ１活性の調節因子およびそのための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016040288A JP2016040288A (ja) | 2016-03-24 |
| JP2016040288A5 true JP2016040288A5 (https=) | 2016-05-12 |
| JP6294277B2 JP6294277B2 (ja) | 2018-03-14 |
Family
ID=44647719
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013500159A Active JP5825535B2 (ja) | 2010-03-17 | 2011-03-15 | Ｈｅｃ１活性の調節因子およびそのための方法 |
| JP2015196085A Active JP6294277B2 (ja) | 2010-03-17 | 2015-10-01 | Ｈｅｃ１活性の調節因子およびそのための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013500159A Active JP5825535B2 (ja) | 2010-03-17 | 2011-03-15 | Ｈｅｃ１活性の調節因子およびそのための方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8946268B2 (https=) |
| EP (1) | EP2547676B1 (https=) |
| JP (2) | JP5825535B2 (https=) |
| KR (1) | KR101609856B1 (https=) |
| CN (2) | CN105906617B (https=) |
| AU (2) | AU2011227398C1 (https=) |
| BR (1) | BR112012023355A2 (https=) |
| CA (1) | CA2793311C (https=) |
| ES (1) | ES2557465T3 (https=) |
| MX (2) | MX2012010664A (https=) |
| MY (1) | MY192693A (https=) |
| NZ (1) | NZ602121A (https=) |
| RU (1) | RU2576036C2 (https=) |
| SG (1) | SG183853A1 (https=) |
| WO (1) | WO2011115998A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101609856B1 (ko) * | 2010-03-17 | 2016-04-07 | 타이벡스 세라피틱스 코포레이션 | Ｈｅｃ１ 활성의 조절인자 및 이의 방법 |
| CN102336720B (zh) * | 2011-03-02 | 2016-01-13 | 华中科技大学 | 2-氨基噻唑衍生物及制备方法和应用 |
| DE102011083271A1 (de) * | 2011-09-23 | 2013-03-28 | Beiersdorf Ag | Aromatische Amidothiazole, deren kosmetische oder dermatologische Verwendung sowie kosmetische oder dermatologische Zubereitungen mit einem Gehalt an solchen Aromatischen Amidothiazolen |
| CN103058949A (zh) * | 2011-10-18 | 2013-04-24 | 华东理工大学 | 做为dhodh抑制剂的噻唑衍生物及其应用 |
| ES2736999T3 (es) | 2011-11-21 | 2020-01-09 | Taivex Therapeutics Corp | Biomarcadores para cánceres que responden a moduladores de la actividad de Hec1 |
| US11071736B2 (en) * | 2011-11-21 | 2021-07-27 | Taivex Therapeutics Corporation | Modulators of HEC1 activity and methods therefor |
| TWI640519B (zh) | 2011-11-29 | 2018-11-11 | 泰緯生命科技股份有限公司 | Ｈｅｃ１活性調控因子及其調節方法 |
| ES2681027T3 (es) * | 2012-02-01 | 2018-09-11 | City Of Hope | Inhibidores de la ribonucleótida reductasa y métodos de uso |
| US9422275B2 (en) * | 2013-07-20 | 2016-08-23 | The Regents Of The University Of California | Small molecule modifiers of the HEC1-NEK2 interaction in G2/M |
| WO2017019772A1 (en) * | 2015-07-27 | 2017-02-02 | Sanford Burnham Prebys Medical Discovery Institute | Modulators of myocyte lipid accumulation and insulin resistance and methods of use thereof |
| WO2017087885A1 (en) | 2015-11-19 | 2017-05-26 | Dana-Farber Cancer Institute, Inc. | Methods of identifying compounds that interfere with erg-driven misguidance of baf complexes in tmprss2-erg driven prostate cancers |
| US11497752B2 (en) | 2018-01-30 | 2022-11-15 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| WO2019169135A1 (en) * | 2018-02-28 | 2019-09-06 | University Of Southern California | Compositions and methods for modulating inflammatory and degenerative disorder |
| WO2020081588A1 (en) | 2018-10-17 | 2020-04-23 | Dana-Farber Cancer Institute, Inc. | Swi/snf family chromatin remodeling complexes and uses thereof |
| US12509453B2 (en) | 2019-01-29 | 2025-12-30 | Foghorn Therapeutics Inc. | BRM/BRG1 inhibitors and uses thereof |
| US12384776B2 (en) | 2019-01-29 | 2025-08-12 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| AU2021213811A1 (en) | 2020-01-29 | 2022-07-28 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| US12383555B2 (en) | 2020-05-20 | 2025-08-12 | Foghorn Therapeutics Inc. | Methods of treating cancers |
| ES2989812T3 (es) * | 2020-06-15 | 2024-11-27 | Dsm Ip Assets Bv | Proceso para la fabricación de alquilamidotiazoles |
| CN111925377B (zh) * | 2020-08-31 | 2022-05-31 | 上海应用技术大学 | 对位取代的二氢呋喃香豆素类神经氨酸酶抑制剂及其制备方法和应用 |
| US12606553B2 (en) | 2021-03-09 | 2026-04-21 | Foghorn Therapeutics Inc. | Crystalline forms, compositions containing same, and methods of their use |
| CN116554122B (zh) | 2023-06-29 | 2023-09-19 | 南京桦冠生物技术有限公司 | α-酮酸酰胺或取代草酸酰胺酯类化合物及其组合物 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6014A (en) * | 1849-01-09 | Stop-motion for drawing-frames | ||
| US5011A (en) * | 1847-03-13 | V boring-machine | ||
| FR2677356B1 (fr) * | 1991-06-05 | 1995-03-17 | Sanofi Sa | Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant. |
| FR2701708B1 (fr) * | 1993-02-19 | 1995-05-19 | Sanofi Elf | Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament. |
| CN100357283C (zh) * | 2002-04-02 | 2007-12-26 | 中国科学院上海药物研究所 | 一类甲硫氨酰氨肽酶抑制剂 |
| AU2003250831A1 (en) | 2002-06-12 | 2003-12-31 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Use of hec1 antagonists in the treatment of proliferative disorders and cancer |
| WO2004033666A2 (en) | 2002-10-11 | 2004-04-22 | Board Of Regents, The University Of Texas System | Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases |
| FR2854158B1 (fr) * | 2003-04-25 | 2006-11-17 | Sanofi Synthelabo | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique |
| ZA200602755B (en) * | 2003-09-06 | 2007-06-27 | Vertex Pharma | Modulators of ATP-binding cassette transporters |
| FR2872813B1 (fr) | 2004-07-09 | 2007-01-19 | Sanofi Synthelabo | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
| CN101048158A (zh) * | 2004-08-13 | 2007-10-03 | 健泰科生物技术公司 | 利用atp的酶的噻唑－类抑制剂 |
| UA92746C2 (en) * | 2005-05-09 | 2010-12-10 | Акилайон Фармасьютикалз, Инк. | Thiazole compounds and methods of use |
| JP4612487B2 (ja) * | 2005-06-30 | 2011-01-12 | キョーラク株式会社 | 容器のキャップ |
| WO2007004038A1 (en) | 2005-07-05 | 2007-01-11 | Pfizer Products Inc. | Aminothiazole derivatives as agonists of the thrombopoietin receptor |
| WO2007008541A2 (en) * | 2005-07-08 | 2007-01-18 | Kalypsys, Inc. | Cellular cholesterol absorption modifiers |
| US20070032531A1 (en) | 2005-08-04 | 2007-02-08 | Apogee Biotechnology Corporation | Sphingosine kinase inhibitors and methods of their use |
| WO2007131071A2 (en) | 2006-05-02 | 2007-11-15 | Washington State University | Mig-7 as a specific anticancer target |
| WO2008124000A2 (en) * | 2007-04-02 | 2008-10-16 | Ligand Pharmaceuticals Incorporated | Thiazole derivatives as androgen receptor modulator compounds |
| JP4986749B2 (ja) * | 2007-07-09 | 2012-07-25 | 富士フイルム株式会社 | 圧力測定用材料 |
| WO2009014674A1 (en) * | 2007-07-23 | 2009-01-29 | Sirtris Pharmaceuticals, Inc. | Heterocyclylamides as gut microsomal triglyceride transport protein inhibitors |
| EP2300004A4 (en) * | 2008-05-15 | 2012-05-30 | Univ Duke | COMPOSITIONS AND METHODS RELATED TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING CONNECTIONS AND OBJECTS THEREFOR |
| US8324385B2 (en) * | 2008-10-30 | 2012-12-04 | Madrigal Pharmaceuticals, Inc. | Diacylglycerol acyltransferase inhibitors |
| EP2309273B1 (en) | 2009-09-16 | 2016-05-18 | ZEILLINGER, Robert | Novel tumor marker determination |
| KR101609856B1 (ko) | 2010-03-17 | 2016-04-07 | 타이벡스 세라피틱스 코포레이션 | Ｈｅｃ１ 활성의 조절인자 및 이의 방법 |
| ES2736999T3 (es) | 2011-11-21 | 2020-01-09 | Taivex Therapeutics Corp | Biomarcadores para cánceres que responden a moduladores de la actividad de Hec1 |
-
2011
- 2011-03-15 KR KR1020127027026A patent/KR101609856B1/ko active Active
- 2011-03-15 NZ NZ602121A patent/NZ602121A/en unknown
- 2011-03-15 CN CN201610159130.9A patent/CN105906617B/zh active Active
- 2011-03-15 ES ES11756862.6T patent/ES2557465T3/es active Active
- 2011-03-15 CN CN201180024772.3A patent/CN103038231B/zh active Active
- 2011-03-15 MY MYPI2012003984A patent/MY192693A/en unknown
- 2011-03-15 WO PCT/US2011/028532 patent/WO2011115998A2/en not_active Ceased
- 2011-03-15 CA CA2793311A patent/CA2793311C/en active Active
- 2011-03-15 US US13/048,709 patent/US8946268B2/en active Active
- 2011-03-15 EP EP11756862.6A patent/EP2547676B1/en active Active
- 2011-03-15 BR BR112012023355A patent/BR112012023355A2/pt not_active Application Discontinuation
- 2011-03-15 AU AU2011227398A patent/AU2011227398C1/en active Active
- 2011-03-15 MX MX2012010664A patent/MX2012010664A/es active IP Right Grant
- 2011-03-15 RU RU2012144022/04A patent/RU2576036C2/ru active
- 2011-03-15 JP JP2013500159A patent/JP5825535B2/ja active Active
- 2011-03-15 SG SG2012064762A patent/SG183853A1/en unknown
- 2011-03-15 MX MX2015015934A patent/MX346395B/es unknown
-
2014
- 2014-08-11 AU AU2014210678A patent/AU2014210678B2/en active Active
- 2014-10-29 US US14/527,087 patent/US9409902B2/en active Active
-
2015
- 2015-10-01 JP JP2015196085A patent/JP6294277B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016040288A5 (https=) | ||
| JP2015505296A5 (https=) | ||
| JP2013510120A5 (https=) | ||
| JP2013531031A5 (https=) | ||
| JP2017525730A5 (https=) | ||
| JP2016515561A5 (https=) | ||
| JP2014505107A5 (https=) | ||
| JP2019524883A5 (https=) | ||
| JP2016506960A5 (https=) | ||
| JP2016503793A5 (https=) | ||
| JP2018524390A5 (https=) | ||
| JP2020097577A5 (https=) | ||
| RU2016105581A (ru) | Способ лечения острого, хронического и подострого кашля и непреодолимого желания откашляться | |
| JP2016528301A5 (https=) | ||
| JP2016518328A5 (https=) | ||
| JP2013537203A5 (https=) | ||
| JP2015501833A5 (https=) | ||
| JP2015508103A5 (https=) | ||
| JP2014528464A5 (https=) | ||
| JP2014510147A5 (https=) | ||
| JP2017517538A5 (https=) | ||
| JP2011513410A5 (https=) | ||
| JP2019512535A5 (https=) | ||
| JP2013545823A5 (https=) | ||
| JP2016531126A5 (https=) |