JP2019501936A5 - - Google Patents

Download PDF

Info

Publication number
JP2019501936A5
JP2019501936A5 JP2018536433A JP2018536433A JP2019501936A5 JP 2019501936 A5 JP2019501936 A5 JP 2019501936A5 JP 2018536433 A JP2018536433 A JP 2018536433A JP 2018536433 A JP2018536433 A JP 2018536433A JP 2019501936 A5 JP2019501936 A5 JP 2019501936A5
Authority
JP
Japan
Prior art keywords
unsubstituted
oxo
diazaspiro
methyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018536433A
Other languages
English (en)
Japanese (ja)
Other versions
JP6862457B2 (ja
JP2019501936A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2017/025004 external-priority patent/WO2017121646A1/en
Publication of JP2019501936A publication Critical patent/JP2019501936A/ja
Publication of JP2019501936A5 publication Critical patent/JP2019501936A5/ja
Priority to JP2021056938A priority Critical patent/JP7148665B2/ja
Application granted granted Critical
Publication of JP6862457B2 publication Critical patent/JP6862457B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018536433A 2016-01-13 2017-01-13 ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 Expired - Fee Related JP6862457B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021056938A JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16151011 2016-01-13
EP16151011.0 2016-01-13
PCT/EP2017/025004 WO2017121646A1 (en) 2016-01-13 2017-01-13 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021056938A Division JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Publications (3)

Publication Number Publication Date
JP2019501936A JP2019501936A (ja) 2019-01-24
JP2019501936A5 true JP2019501936A5 (enExample) 2020-02-27
JP6862457B2 JP6862457B2 (ja) 2021-04-21

Family

ID=55129632

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018536433A Expired - Fee Related JP6862457B2 (ja) 2016-01-13 2017-01-13 ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体
JP2021056938A Expired - Fee Related JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021056938A Expired - Fee Related JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Country Status (28)

Country Link
US (7) US20170197919A1 (enExample)
EP (2) EP3722283A1 (enExample)
JP (2) JP6862457B2 (enExample)
KR (1) KR20180100592A (enExample)
CN (1) CN108699005B (enExample)
AR (1) AR107361A1 (enExample)
AU (1) AU2017207467B2 (enExample)
BR (1) BR112018014302B1 (enExample)
CA (1) CA3011175C (enExample)
CL (1) CL2018001913A1 (enExample)
CO (1) CO2018008445A2 (enExample)
CY (1) CY1122882T1 (enExample)
DK (1) DK3402783T3 (enExample)
EA (1) EA037649B1 (enExample)
EC (1) ECSP18060820A (enExample)
ES (1) ES2803354T3 (enExample)
HR (1) HRP20200656T1 (enExample)
HU (1) HUE049374T2 (enExample)
IL (1) IL260495B (enExample)
LT (1) LT3402783T (enExample)
MX (1) MX379201B (enExample)
PE (1) PE20181647A1 (enExample)
PL (1) PL3402783T3 (enExample)
PT (1) PT3402783T (enExample)
RS (1) RS60223B1 (enExample)
SI (1) SI3402783T1 (enExample)
TW (1) TWI635081B (enExample)
WO (1) WO2017121646A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6893517B2 (ja) 2016-01-13 2021-06-23 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ３−（（ヘテロ−）アリール）−アルキル−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体
TWI635082B (zh) 2016-01-13 2018-09-11 歌林達有限公司 ３－（（雜－）芳基）－８－胺基－２－側氧－１,３－二氮雜－螺－［４.５］－癸烷衍生物
DK3402783T3 (da) * 2016-01-13 2020-05-04 Gruenenthal Gmbh 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decan-derivater
MX378995B (es) 2016-01-13 2025-03-11 Gruenenthal Gmbh Derivados de 3-(carboximetil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano.
RS60855B1 (sr) 2016-01-13 2020-10-30 Gruenenthal Gmbh Derivati 8-amino-2-okso-1,3-diaza-spiro-[4.5]-dekana
KR102866751B1 (ko) * 2020-06-09 2025-10-01 삼성디스플레이 주식회사 축합환 화합물을 포함한 발광 소자 및 상기 발광 소자를 포함한 전자 장치
AU2022322838B2 (en) * 2021-08-02 2024-12-12 Jiangsu Nhwa Pharmaceutical Co., Ltd Oxaspiro derivative, and preparation method therefor and use thereof
US20240400537A1 (en) 2023-04-25 2024-12-05 Gruenenthal Gmbh Cis-8-(3,5-difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2734265B1 (fr) 1995-05-17 1997-06-13 Adir Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant
RU2268883C2 (ru) 2001-04-18 2006-01-27 Эро-Селтик, С.А. Аналоги ноницептина и фармацевтическая композиция на их основе
DE10130020A1 (de) 2001-06-25 2003-12-04 Gruenenthal Gmbh Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate
DE10210195B4 (de) 2002-03-07 2005-12-15 Schwarz Pharma Ag Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
ZA200510329B (en) 2003-05-23 2007-04-25 Zealand Pharma As Triaza-spiro compounds as nociceptin analogues and uses thereof
JO2676B1 (en) 2004-04-06 2012-06-17 جانسين فارماسوتيكا ان. في Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
AU2007312391B2 (en) 2006-10-19 2012-06-21 F. Hoffmann-La Roche Ag Imidazolone and imidazolidinone derivatives as 11b-HSD1 inhibitors for diabetes
EP2150552B1 (en) 2007-04-09 2013-01-02 Janssen Pharmaceutica NV 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression
KR20120075500A (ko) * 2008-03-27 2012-07-06 그뤼넨탈 게엠베하 치환된 4-아미노사이클로헥산 유도체
TWI582092B (zh) 2010-07-28 2017-05-11 歌林達股份有限公司 順式－四氫－螺旋（環己烷－１,１’－吡啶［３,４－b］吲哚）－４－胺－衍生物
WO2014106238A1 (en) * 2012-12-31 2014-07-03 Fang, Qun, Kevin Heterocyclic compounds and methods of use thereof
EP3154971A4 (en) 2014-06-13 2017-11-01 Purdue Pharma L.P. Heterocyclic morphinan derivatives and use thereof
MX378995B (es) 2016-01-13 2025-03-11 Gruenenthal Gmbh Derivados de 3-(carboximetil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano.
JP6893517B2 (ja) 2016-01-13 2021-06-23 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ３−（（ヘテロ−）アリール）−アルキル−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体
DK3402783T3 (da) 2016-01-13 2020-05-04 Gruenenthal Gmbh 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decan-derivater
RS60855B1 (sr) 2016-01-13 2020-10-30 Gruenenthal Gmbh Derivati 8-amino-2-okso-1,3-diaza-spiro-[4.5]-dekana

Similar Documents

Publication Publication Date Title
JP2019510799A5 (enExample)
JP7465174B2 (ja) ナトリウムチャネルの調節剤として有用なピリドンアミドのプロドラッグ
JP2023531709A5 (enExample)
JP2022517189A5 (enExample)
KR102842589B1 (ko) 헤모글로빈을 조정할 수 있는 2-포르밀-3-히드록시페닐옥시메틸 화합물
CN114057815B (zh) 作为prmt5抑制剂的、新颖6-6二环芳环取代的核苷
AU2022286438A1 (en) N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamide analogs as modulators of sodium channels
RS67577B1 (sr) N-(hidroksialkil(hetero)aril) tetrahidrofuran karboksamidi kao modulatori natrijumovih kanala
FI3788040T3 (fi) Pyridatsinoneja parp7-inhibiittoreina
JP2021529812A5 (enExample)
TWI636048B (zh) ３－（（雜－）芳基）－烷基－８－胺基－２－側氧－１,３－二氮雜－螺－［４.５］－癸烷衍生物
JP2017518959A5 (enExample)
JP2020530487A5 (enExample)
JP2023531495A5 (enExample)
JP2021528427A5 (enExample)
JP2019501940A5 (enExample)
RU2015107803A (ru) Производные дигидроксипиримидинкарбоновой кислоты и их применение в лечении, облегчении или предотвращении вирусного заболевания
JP2019524861A (ja) グアニジノ基で置換された縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
JP2013520473A5 (enExample)
CN111494386A (zh) 通过jak和pi3k抑制剂组合治疗b细胞恶性肿瘤
JP2007501793A5 (enExample)
JP2022550353A5 (enExample)
HRP20171696T1 (hr) 3,4-dihidroizokinolin-2(1h)-ilni spojevi
EP4543881A1 (en) Compounds and method for pkmyt1 inhibition
TWI635081B (zh) ３－（羧乙基）－８－氨基－２－側氧－１,３－二氮雜－螺－［４.５］－癸烷衍生物