|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
EP0563475B1
(en)
|
1992-03-25 |
2000-05-31 |
Immunogen Inc |
Cell binding agent conjugates of derivatives of CC-1065
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
CA2722378C
(en)
|
1996-12-03 |
2015-02-03 |
Amgen Fremont Inc. |
Human antibodies that bind tnf.alpha.
|
|
BRPI9809391B8
(pt)
|
1997-04-14 |
2021-05-25 |
Amgen Res Munich Gmbh |
processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US7067109B1
(en)
|
1998-07-13 |
2006-06-27 |
Board Of Regents, The University Of Texas System |
Cancer treatment kits comprising therapeutic conjugates that bind to aminophospholipids
|
|
CA2388063C
(en)
|
1999-11-24 |
2010-06-08 |
Immunogen, Inc. |
Cytotoxic agents comprising taxanes and their therapeutic use
|
|
WO2001058479A1
(en)
|
2000-02-08 |
2001-08-16 |
The Penn State Research Foundation |
Immunotherapy using interleukin 13 receptor subunit alpha 2
|
|
NZ527283A
(en)
|
2001-01-29 |
2006-03-31 |
Biogen Idec Inc |
Modified antibodies and methods of use
|
|
KR100863624B1
(ko)
|
2001-05-11 |
2008-10-15 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
Cd26을 발현하는 세포와 연관된 질환의 치료제로사용되는 항-cd26 단클론항체
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
US20040161776A1
(en)
*
|
2001-10-23 |
2004-08-19 |
Maddon Paul J. |
PSMA formulations and uses thereof
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US6756397B2
(en)
|
2002-04-05 |
2004-06-29 |
Immunogen, Inc. |
Prodrugs of CC-1065 analogs
|
|
BR0313197A
(pt)
|
2002-08-02 |
2005-08-09 |
Immunogen Inc |
Agentes citotóxicos contendo potentes taxanos e seu uso terapêutico
|
|
DE60336149D1
(de)
|
2002-08-16 |
2011-04-07 |
Immunogen Inc |
Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln
|
|
US20040033228A1
(en)
*
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
ZA200503075B
(en)
|
2002-11-07 |
2006-09-27 |
Immunogen Inc |
Anti-CD33 antibodies and method for treatment of acute myeloid leukemia using the same
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
US7834155B2
(en)
|
2003-07-21 |
2010-11-16 |
Immunogen Inc. |
CA6 antigen-specific cytotoxic conjugate and methods of using the same
|
|
ATE496944T1
(de)
|
2003-07-21 |
2011-02-15 |
Immunogen Inc |
Ca6-antigenspezifisches zytotoxisches konjugat und verfahren zu dessen anwendung
|
|
AR048098A1
(es)
*
|
2004-03-15 |
2006-03-29 |
Wyeth Corp |
Conjugados de caliqueamicina
|
|
DOP2006000029A
(es)
*
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
|
WO2007019232A2
(en)
*
|
2005-08-03 |
2007-02-15 |
Immunogen, Inc. |
Immunoconjugate formulations
|
|
CA2615761A1
(en)
|
2005-08-22 |
2007-03-01 |
Immunogen, Inc. |
Humanized anti-ca6 antibodies and methods of using the same
|
|
CA2790018C
(en)
*
|
2006-12-21 |
2015-02-03 |
Amgen Inc. |
Formulations
|
|
EP2170268A2
(en)
*
|
2007-06-25 |
2010-04-07 |
Amgen, Inc. |
Compositions of specific binding agents to hepatocyte growth factor
|
|
SG189817A1
(en)
|
2008-04-30 |
2013-05-31 |
Immunogen Inc |
Potent conjugates and hydrophilic linkers
|
|
NZ610239A
(en)
|
2008-04-30 |
2014-11-28 |
Immunogen Inc |
Cross-linkers and their uses
|
|
RU2683325C2
(ru)
|
2009-02-05 |
2019-03-28 |
Иммьюноджен, Инк. |
Новые производные бензодиазепина
|
|
CA2771336C
(en)
*
|
2009-09-15 |
2019-11-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Synergistic anti-cd47 therapy for hematologic cancers
|
|
TWI622402B
(zh)
|
2010-02-24 |
2018-05-01 |
免疫遺傳股份有限公司 |
葉酸受體1抗體類和免疫共軛物類及彼等之用途
|
|
SG10201501803YA
(en)
|
2010-03-12 |
2015-05-28 |
Immunogen Inc |
Cd37-binding molecules and immunoconjugates thereof
|
|
SI2528625T1
(sl)
*
|
2010-04-15 |
2013-11-29 |
Spirogen Sarl |
Pirolobenzodiazepini in njihovi konjugati
|
|
BR112012033457A2
(pt)
*
|
2010-07-02 |
2017-04-04 |
Medimmune Llc |
formulações de anticorpo.
|
|
JP5826863B2
(ja)
|
2011-02-15 |
2015-12-02 |
イミュノジェン・インコーポレーテッド |
細胞傷害性ベンゾジアゼピン誘導体
|
|
ME03353B
(me)
|
2011-03-29 |
2019-10-20 |
Immunogen Inc |
Priprema konjugata antitela i majtanzinoida jednostepenim postupkom
|
|
BR112013025415B1
(pt)
|
2011-04-01 |
2021-03-16 |
Immunogen, Inc |
uso de um imunoconjugado antirreceptor de folato 1 (folr1)
|
|
EP2524929A1
(en)
|
2011-05-17 |
2012-11-21 |
Sanofi |
Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
|
|
GB2516808A
(en)
*
|
2013-05-31 |
2015-02-11 |
Innova Biosciences Ltd |
Antibody composition and buffer system therefor
|
|
FR3008463B1
(fr)
|
2013-07-10 |
2015-08-07 |
Hispano Suiza Sa |
Structure compacte de boitier d'entrainement pour turbomachine d'aeronef
|
|
SI3071237T1
(sl)
*
|
2013-11-21 |
2024-11-29 |
Genmab A/S |
Liofilizirana formulacija konjugata protitelo-zdravilo
|
|
CA2935433C
(en)
*
|
2014-01-10 |
2019-04-02 |
Synthon Biopharmaceuticals B.V. |
Duocarmycin anti-her2 antibody drug conjucates with activity against her2 expressing malignancies
|
|
WO2016036804A1
(en)
|
2014-09-03 |
2016-03-10 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
AU2015311987B2
(en)
|
2014-09-03 |
2020-06-04 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
SMT202000614T1
(it)
*
|
2015-06-29 |
2021-01-05 |
Immunogen Inc |
Coniugati di anticorpi ingegnerizzati con cisteina
|
|
AU2016285552B2
(en)
*
|
2015-06-29 |
2022-10-13 |
Immunogen, Inc. |
Anti-CD123 antibodies and conjugates and derivatives thereof
|