JP2019194191A5 - - Google Patents
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- Publication number
- JP2019194191A5 JP2019194191A5 JP2019103598A JP2019103598A JP2019194191A5 JP 2019194191 A5 JP2019194191 A5 JP 2019194191A5 JP 2019103598 A JP2019103598 A JP 2019103598A JP 2019103598 A JP2019103598 A JP 2019103598A JP 2019194191 A5 JP2019194191 A5 JP 2019194191A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- viloxazine
- pharmaceutically acceptable
- acceptable salt
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32315110P | 2010-04-12 | 2010-04-12 | |
| US61/323,151 | 2010-04-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016199937A Division JP2017039754A (ja) | 2010-04-12 | 2016-10-11 | ビロキサジン塩を製造する方法及びその新規な多形 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019194191A JP2019194191A (ja) | 2019-11-07 |
| JP2019194191A5 true JP2019194191A5 (https=) | 2020-01-09 |
Family
ID=44065289
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013505028A Active JP6196551B2 (ja) | 2010-04-12 | 2011-04-12 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2015141683A Pending JP2016006062A (ja) | 2010-04-12 | 2015-07-15 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2016199937A Pending JP2017039754A (ja) | 2010-04-12 | 2016-10-11 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2017227668A Active JP6663413B2 (ja) | 2010-04-12 | 2017-11-28 | ビロキサジン又はその薬学的に許容される塩を製造する方法 |
| JP2019103598A Pending JP2019194191A (ja) | 2010-04-12 | 2019-06-03 | ビロキサジン塩を製造する方法及びその新規な多形 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013505028A Active JP6196551B2 (ja) | 2010-04-12 | 2011-04-12 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2015141683A Pending JP2016006062A (ja) | 2010-04-12 | 2015-07-15 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2016199937A Pending JP2017039754A (ja) | 2010-04-12 | 2016-10-11 | ビロキサジン塩を製造する方法及びその新規な多形 |
| JP2017227668A Active JP6663413B2 (ja) | 2010-04-12 | 2017-11-28 | ビロキサジン又はその薬学的に許容される塩を製造する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US9403783B2 (https=) |
| EP (1) | EP2558437B1 (https=) |
| JP (5) | JP6196551B2 (https=) |
| AU (1) | AU2011240773C1 (https=) |
| CA (4) | CA3215310A1 (https=) |
| ES (1) | ES2552166T3 (https=) |
| MX (5) | MX347218B (https=) |
| WO (1) | WO2011130194A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX347218B (es) * | 2010-04-12 | 2017-04-20 | Supernus Pharmaceuticals Inc | Metodos para producir sales de viloxazina y polimorfos novedosos de las mismas. |
| CN110799191B (zh) | 2017-06-16 | 2023-05-26 | 贝塔制药有限公司 | N-(2-(2-(二甲氨基)乙氧基)-4-甲氧基-5-((4-(1-甲基-1h-吲哚-3-基)嘧啶-2-基)氨基)苯基)丙烯酰胺及其盐的药物制剂 |
| CN108760719A (zh) * | 2018-08-17 | 2018-11-06 | 北京理工大学 | 一种利用拉曼光谱分析cl-20的晶型纯度的方法 |
| KR20260023103A (ko) | 2021-03-18 | 2026-02-20 | 슈퍼너스 파마슈티컬스, 인크. | 치환된 몰폴린의 유도체 및 이의 용도 |
| KR20250134715A (ko) * | 2022-03-18 | 2025-09-11 | 슈퍼너스 파마슈티컬스, 인크. | 치환된 몰폴린의 유도체의 제조 방법 |
| WO2023248154A1 (en) * | 2022-06-22 | 2023-12-28 | Glenmark Life Sciences Limited | Process for the preparation of viloxazine hydrochloride |
| EP4317141A1 (en) | 2022-08-04 | 2024-02-07 | Curia Spain S.A.U. | Process and intermediates for the preparation of viloxazine and other 2-substituted morpholine derivatives |
| CN119707868A (zh) * | 2023-09-27 | 2025-03-28 | 西安远大科创医药科技有限公司 | 一种盐酸维洛沙嗪产品杂质及其合成方法与应用 |
| CN119707851A (zh) * | 2023-09-27 | 2025-03-28 | 西安远大科创医药科技有限公司 | 一种盐酸维洛沙嗪产品杂质及其合成方法与应用 |
| KR20250094621A (ko) * | 2023-12-18 | 2025-06-25 | 주식회사 아스트로젠 | (s)-빌록사진 또는 이의 염의 개선된 제조 방법 |
| WO2025219523A1 (en) | 2024-04-19 | 2025-10-23 | Cambrex Profarmaco Milano S.R.L. | "intermediates and processes for the preparation of viloxazine" |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1138405A (en) | 1966-12-28 | 1969-01-01 | Ici Ltd | Morpholine derivatives |
| US3712890A (en) * | 1969-06-20 | 1973-01-23 | Ici Ltd | Process for making 2-aryloxymethyl morpholines |
| US3857839A (en) * | 1969-06-20 | 1974-12-31 | Ici Ltd | For cyclising 1-aryloxy-3 beta-substituted ethylamino-2-propanols |
| ES411826A1 (es) * | 1973-02-20 | 1976-01-01 | Liade Sa Lab | Procedimiento de obtencion de 1-ariloxi - 2 - propanolami- nas farmacologicamente activos. |
| JPS5188972A (en) | 1975-01-29 | 1976-08-04 | 22*77 indeniruokishimechiru **4 chikanmoruhorinjudotainoseiho | |
| JPS5283677A (en) | 1976-01-01 | 1977-07-12 | Yamanouchi Pharmaceut Co Ltd | Derivative of 2-(7-indenyloxymethyl)-4-substituted morpholine |
| US4711887A (en) * | 1982-04-23 | 1987-12-08 | Imperial Chemical Industries Plc | Hydrazinopyridazine compounds |
| JPH06306025A (ja) * | 1992-11-30 | 1994-11-01 | Sankyo Co Ltd | ジアリールアルカン誘導体 |
| US5760069A (en) * | 1995-02-08 | 1998-06-02 | Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 | Method of treatment for decreasing mortality resulting from congestive heart failure |
| CA2214034A1 (en) * | 1995-03-10 | 1996-09-19 | University Of Iowa Research Foundation | Preparation of n-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and n-arylmethyl-ethanol-amine sulphonate esters as intermediates |
| AUPO565997A0 (en) * | 1997-03-17 | 1997-04-10 | Fujisawa Pharmaceutical Co., Ltd. | Propanolamine derivatives |
| US6953855B2 (en) * | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| DE19919153A1 (de) * | 1999-04-27 | 2000-11-02 | Consortium Elektrochem Ind | Herstellung von acrylierten flüssigkristallinen Verbindungen |
| FR2796069B3 (fr) * | 1999-07-09 | 2001-08-24 | Sanofi Synthelabo | Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes |
| PT1257277E (pt) * | 2000-02-24 | 2005-09-30 | Pharmacia & Upjohn Co Llc | Novas combinacoes de farmacos |
| US20030040436A1 (en) * | 2000-10-23 | 2003-02-27 | Emerson Ralph W. | Use of benzyl ester compositions for controlling non-arthropod pest populations |
| TWI329105B (en) * | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| US7326790B2 (en) * | 2003-05-02 | 2008-02-05 | Rigel Pharmaceuticals, Inc. | Diphenylisoxazole compounds and hydro isomers thereof |
| JP4210573B2 (ja) * | 2003-10-10 | 2009-01-21 | 花王株式会社 | 置換フェノキシプロパノールアミン類 |
| CA2567935C (en) * | 2004-05-27 | 2009-10-27 | Pfizer Limited | Aminopyridine derivatives as selective dopamine d3 agonists |
| US20060118002A1 (en) * | 2004-12-03 | 2006-06-08 | Sud-Chemie Inc. | Organoclay composition containing quat mixtures |
| KR20080045266A (ko) * | 2005-09-06 | 2008-05-22 | 스미스클라인 비참 코포레이션 | 벤즈이미다졸 티오펜을 제조하기 위한 위치선택적인 방법 |
| PE20070855A1 (es) * | 2005-12-02 | 2007-10-14 | Bayer Pharmaceuticals Corp | Derivados de 4-amino-pirrolotriazina sustituida como inhibidores de quinasas |
| CN100415709C (zh) * | 2006-05-15 | 2008-09-03 | 西北大学 | β-(3,4-二羟基苯基)-α-羟基丙酸冰片酯、其合成方法和用途 |
| WO2008047388A2 (en) | 2006-10-20 | 2008-04-24 | Ind-Swift Laboratories Limited | Improved process for the preparation of ranolazine |
| ES2539947T3 (es) * | 2008-06-02 | 2015-07-07 | Cipla Limited | Procedimiento para la síntesis de arformoterol |
| EP2341912B1 (en) * | 2008-09-05 | 2014-01-22 | Supernus Pharmaceuticals, Inc. | Method of treatment of attention deficit/hyperactivity disorder (adhd) |
| US9296940B2 (en) * | 2009-12-21 | 2016-03-29 | Baker Hughes Incorporated | Dithiazine derivatives |
| MX347218B (es) * | 2010-04-12 | 2017-04-20 | Supernus Pharmaceuticals Inc | Metodos para producir sales de viloxazina y polimorfos novedosos de las mismas. |
| TWI596088B (zh) * | 2011-01-25 | 2017-08-21 | 陶氏農業科學公司 | 4-胺基-6-(經取代的苯基)吡啶甲酸酯及6-胺基-2-(經取代的苯基)-4-嘧啶羧酸酯之芳烷酯以及其等作為除草劑之用途 |
| EP2922849B1 (en) * | 2012-11-21 | 2017-07-12 | RaQualia Pharma Inc. | Polymorphs of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2h-pyran-4-carboxylic acid as 5-hydroxytryptamine-4 (5-ht4) receptor agonists for the treatment of gastrointestinal diseases |
-
2011
- 2011-04-12 MX MX2014010356A patent/MX347218B/es unknown
- 2011-04-12 MX MX2014010369A patent/MX357614B/es unknown
- 2011-04-12 AU AU2011240773A patent/AU2011240773C1/en active Active
- 2011-04-12 WO PCT/US2011/032013 patent/WO2011130194A2/en not_active Ceased
- 2011-04-12 CA CA3215310A patent/CA3215310A1/en active Pending
- 2011-04-12 MX MX2014010358A patent/MX357613B/es unknown
- 2011-04-12 JP JP2013505028A patent/JP6196551B2/ja active Active
- 2011-04-12 CA CA3126096A patent/CA3126096C/en active Active
- 2011-04-12 EP EP11718804.5A patent/EP2558437B1/en active Active
- 2011-04-12 CA CA2795408A patent/CA2795408C/en active Active
- 2011-04-12 US US13/084,612 patent/US9403783B2/en active Active
- 2011-04-12 MX MX2012011821A patent/MX2012011821A/es active IP Right Grant
- 2011-04-12 MX MX2014010368A patent/MX355697B/es unknown
- 2011-04-12 CA CA2992219A patent/CA2992219A1/en not_active Abandoned
- 2011-04-12 ES ES11718804.5T patent/ES2552166T3/es active Active
-
2014
- 2014-12-19 US US14/577,380 patent/US9434703B2/en active Active
-
2015
- 2015-07-15 JP JP2015141683A patent/JP2016006062A/ja active Pending
-
2016
- 2016-06-24 US US15/192,098 patent/US10005743B2/en active Active
- 2016-10-11 JP JP2016199937A patent/JP2017039754A/ja active Pending
-
2017
- 2017-11-28 JP JP2017227668A patent/JP6663413B2/ja active Active
-
2018
- 2018-05-24 US US15/988,190 patent/US10160733B2/en active Active
- 2018-11-13 US US16/189,299 patent/US20190300492A1/en not_active Abandoned
-
2019
- 2019-06-03 JP JP2019103598A patent/JP2019194191A/ja active Pending
-
2021
- 2021-08-04 US US17/393,834 patent/US20220024885A1/en active Pending
-
2025
- 2025-09-15 US US19/328,907 patent/US20260008759A1/en active Pending
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