JP2019081762A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019081762A5 JP2019081762A5 JP2018238486A JP2018238486A JP2019081762A5 JP 2019081762 A5 JP2019081762 A5 JP 2019081762A5 JP 2018238486 A JP2018238486 A JP 2018238486A JP 2018238486 A JP2018238486 A JP 2018238486A JP 2019081762 A5 JP2019081762 A5 JP 2019081762A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- fluoroalkyl
- cycloalkyl
- alkoxy
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261713113P | 2012-10-12 | 2012-10-12 | |
| US61/713,113 | 2012-10-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536142A Division JP6515409B2 (ja) | 2012-10-12 | 2013-10-11 | ベンズアミド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019081762A JP2019081762A (ja) | 2019-05-30 |
| JP2019081762A5 true JP2019081762A5 (enExample) | 2019-07-04 |
| JP6632701B2 JP6632701B2 (ja) | 2020-01-22 |
Family
ID=49551580
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536142A Expired - Fee Related JP6515409B2 (ja) | 2012-10-12 | 2013-10-11 | ベンズアミド |
| JP2018238486A Expired - Fee Related JP6632701B2 (ja) | 2012-10-12 | 2018-12-20 | ベンズアミド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536142A Expired - Fee Related JP6515409B2 (ja) | 2012-10-12 | 2013-10-11 | ベンズアミド |
Country Status (42)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201427947A (zh) * | 2012-10-12 | 2014-07-16 | Lundbeck & Co As H | 環狀胺 |
| TWI598325B (zh) | 2012-10-12 | 2017-09-11 | Ｈ 朗德貝克公司 | 苯甲醯胺類 |
| US9718774B2 (en) | 2012-12-12 | 2017-08-01 | Idorsia Pharmaceuticals Ltd | Indole carboxamide derivatives as P2X7 receptor antagonist |
| AR094053A1 (es) | 2012-12-18 | 2015-07-08 | Actelion Pharmaceuticals Ltd | Derivados de indol carboxamida como antagonistas del receptor p2x₇ |
| EP2956135B1 (en) | 2013-01-22 | 2016-11-16 | Actelion Pharmaceuticals Ltd. | Heterocyclic amide derivatives as p2x7 receptor antagonists |
| KR102220847B1 (ko) | 2013-01-22 | 2021-02-26 | 이도르시아 파마슈티컬스 리미티드 | Ｐ2ｘ7 수용체 길항제로서의 헤테로시클릭 아미드 유도체 |
| CN105503787A (zh) * | 2015-12-31 | 2016-04-20 | 阜阳欣奕华材料科技有限公司 | 一种索非布韦中间体的纯化方法 |
| CN106366056B (zh) * | 2016-08-26 | 2018-12-11 | 常州市阳光药业有限公司 | 3-氨甲基四氢呋喃的制备方法 |
| PT3609868T (pt) * | 2017-03-13 | 2023-12-18 | Raqualia Pharma Inc | Derivados de tetra-hidroquinolina como antagonistas do recetor p2x7 |
| TWI903299B (zh) | 2018-03-08 | 2025-11-01 | 美商英塞特公司 | 作為PI3K-γ抑制劑之胺基吡嗪二醇化合物 |
| WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
| EP3962493A2 (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor |
| EP4238974A4 (en) * | 2020-10-28 | 2024-10-23 | Adlai Nortye Biopharma Co., Ltd. | HIGH ACTIVITY WNT PATHWAY INHIBITOR COMPOUND |
| JP2024528175A (ja) * | 2021-08-02 | 2024-07-26 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺微生物ピラゾール誘導体 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1445707A1 (de) | 1962-05-05 | 1969-03-13 | Hoechst Ag | Piperidinverbindungen und Verfahren zu ihrer Herstellung |
| US3435038A (en) * | 1965-06-01 | 1969-03-25 | Sandoz Ag | 5,6,7,9,10,14b-hexahydroisoquinolo (2,1-d) benzo (1,4) diazepines |
| US6194458B1 (en) | 1998-10-30 | 2001-02-27 | Merck & Co., Inc. | Benzamide potassium channel inhibitors |
| US6632836B1 (en) * | 1998-10-30 | 2003-10-14 | Merck & Co., Inc. | Carbocyclic potassium channel inhibitors |
| US6303637B1 (en) * | 1998-10-30 | 2001-10-16 | Merck & Co., Inc. | Heterocyclic potassium channel inhibitors |
| SE0003476D0 (sv) * | 2000-09-28 | 2000-09-28 | Astrazeneca Ab | Compounds |
| TW200300083A (en) | 2001-11-12 | 2003-05-16 | Pfizer Prod Inc | Benzamide, heteroarylamide and reverse amides |
| PA8557501A1 (es) * | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| TW200403058A (en) * | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| PA8591801A1 (es) * | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | Inhibidores benzamidicos del receptor p2x7. |
| MXPA05012086A (es) * | 2003-05-12 | 2006-02-22 | Pfizer Prod Inc | Inhibidores de benzamida del receptor p2x7. |
| KR20060073930A (ko) | 2003-08-08 | 2006-06-29 | 버텍스 파마슈티칼스 인코포레이티드 | 통증 치료시 나트륨 또는 칼슘 채널 차단제로서 유용한헤테로아릴아미노설포닐페닐 유도체 |
| TWI368482B (en) * | 2003-12-19 | 2012-07-21 | Bayer Sas | New 2-pyridinylethylbenzamide derivatives |
| CA2560256C (en) * | 2004-03-24 | 2013-02-19 | Merck & Co., Inc. | Heteroaryl piperidine glycine transporter inhibitors |
| JP2008504363A (ja) * | 2004-06-29 | 2008-02-14 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | Ｐ２ｘ７受容体のベンズアミド阻害剤を利用する併用療法 |
| JP5055493B2 (ja) * | 2004-12-21 | 2012-10-24 | メルク シャープ エンド ドーム リミテッド | Ｇｌｙｔ１阻害薬としてのピペリジンおよびアゼチジン誘導体 |
| EP1844003A4 (en) * | 2005-01-27 | 2010-09-22 | Astrazeneca Ab | NEW BIAROMATIC COMPOUNDS AS INHIBITORS OF THE P2X7 RECEPTOR |
| AU2006258842B2 (en) * | 2005-06-13 | 2011-09-15 | Merck Sharp & Dohme Limited | Therapeutic agents |
| ES2320042T3 (es) | 2005-10-19 | 2009-05-18 | F. Hoffmann-La Roche Ag | Inhibidores de transcriptasa reversa con nucleosidos de n-fenil fenilacetamida. |
| JP2009057282A (ja) | 2005-12-19 | 2009-03-19 | Astellas Pharma Inc | カルボン酸誘導体又はその塩 |
| TWI435863B (zh) | 2006-03-20 | 2014-05-01 | Nihon Nohyaku Co Ltd | Ｎ-２-（雜）芳基乙基甲醯胺衍生物及含該衍生物之蟲害防治劑 |
| AR067381A1 (es) * | 2007-07-02 | 2009-10-07 | Syngenta Participations Ag | Derivados amido y/o amino tiofenos con actividad microbicida,composiciones que los contienen y usos de las mismas para prevenir y/o controlar la infeccion de plantas por microorganismos patogenos,preferentemente hongos. |
| US8642660B2 (en) * | 2007-12-21 | 2014-02-04 | The University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| CA2722035C (en) * | 2008-04-22 | 2016-10-11 | Janssen Pharmaceutica Nv | Quinoline or isoquinoline substituted p2x7 antagonists |
| ES2345527B1 (es) * | 2008-10-08 | 2011-09-08 | Hospital Clinic I Provincial De Barcelona | Sustancias bloqueadoras de los canales kv 1.3 para el tratamiento de enfermedades asociadas a hiperplasia de la intima. |
| WO2012007868A2 (en) | 2010-07-12 | 2012-01-19 | Pfizer Limited | Chemical compounds |
| KR101856577B1 (ko) * | 2011-03-02 | 2018-05-10 | 고쿠리츠다이가쿠호우진 도쿄다이가쿠 | 내부 기생충 방제제 |
| PE20141996A1 (es) * | 2011-11-02 | 2014-11-28 | Bayer Ip Gmbh | Compuestos con actividad nematicida |
| JP6126115B2 (ja) * | 2011-11-25 | 2017-05-10 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 殺内部寄生生物剤としてのアリールカルボキサミド類及びヘタリールカルボキサミド類の使用 |
| TW201427947A (zh) * | 2012-10-12 | 2014-07-16 | Lundbeck & Co As H | 環狀胺 |
| TWI598325B (zh) | 2012-10-12 | 2017-09-11 | Ｈ 朗德貝克公司 | 苯甲醯胺類 |
-
2013
- 2013-10-09 TW TW102136498A patent/TWI598325B/zh active
- 2013-10-10 US US14/050,431 patent/US9102591B2/en active Active
- 2013-10-10 AR ARP130103681A patent/AR092973A1/es unknown
- 2013-10-11 HU HUE13786633A patent/HUE038223T2/hu unknown
- 2013-10-11 SM SM20180136T patent/SMT201800136T1/it unknown
- 2013-10-11 PT PT137866331T patent/PT2906546T/pt unknown
- 2013-10-11 HR HRP20180272TT patent/HRP20180272T1/hr unknown
- 2013-10-11 PL PL13786633T patent/PL2906546T3/pl unknown
- 2013-10-11 RS RS20180243A patent/RS56925B1/sr unknown
- 2013-10-11 GE GEAP201313785A patent/GEP201706621B/en unknown
- 2013-10-11 DK DK13786633.1T patent/DK2906546T3/en active
- 2013-10-11 JP JP2015536142A patent/JP6515409B2/ja not_active Expired - Fee Related
- 2013-10-11 TR TR2018/02992T patent/TR201802992T4/tr unknown
- 2013-10-11 AU AU2013328584A patent/AU2013328584B2/en not_active Ceased
- 2013-10-11 RU RU2015113320A patent/RU2015113320A/ru not_active Application Discontinuation
- 2013-10-11 KR KR1020157009187A patent/KR20150067188A/ko not_active Withdrawn
- 2013-10-11 BR BR112015008117A patent/BR112015008117A2/pt not_active IP Right Cessation
- 2013-10-11 MX MX2015004412A patent/MX369717B/es active IP Right Grant
- 2013-10-11 SI SI201330967T patent/SI2906546T1/en unknown
- 2013-10-11 ES ES13786633.1T patent/ES2662523T3/es active Active
- 2013-10-11 CN CN201380052671.6A patent/CN104884445B/zh not_active Expired - Fee Related
- 2013-10-11 AP AP2015008406A patent/AP2015008406A0/xx unknown
- 2013-10-11 EA EA201590562A patent/EA026396B1/ru not_active IP Right Cessation
- 2013-10-11 SG SG11201502680QA patent/SG11201502680QA/en unknown
- 2013-10-11 NZ NZ630830A patent/NZ630830A/en not_active IP Right Cessation
- 2013-10-11 LT LTEP13786633.1T patent/LT2906546T/lt unknown
- 2013-10-11 CA CA2887096A patent/CA2887096C/en active Active
- 2013-10-11 EP EP13786633.1A patent/EP2906546B1/en active Active
- 2013-10-11 ME MEP-2018-51A patent/ME02982B/me unknown
- 2013-10-11 WO PCT/EP2013/071247 patent/WO2014057078A1/en not_active Ceased
- 2013-10-11 PE PE2015000466A patent/PE20150709A1/es not_active Application Discontinuation
-
2014
- 2014-09-18 NO NO14185271A patent/NO2851818T3/no unknown
-
2015
- 2015-03-23 IL IL237914A patent/IL237914A0/en unknown
- 2015-03-23 TN TNP2015000107A patent/TN2015000107A1/fr unknown
- 2015-03-26 CR CR20150171A patent/CR20150171A/es unknown
- 2015-03-26 DO DO2015000076A patent/DOP2015000076A/es unknown
- 2015-04-06 PH PH12015500746A patent/PH12015500746A1/en unknown
- 2015-04-08 NI NI201500050A patent/NI201500050A/es unknown
- 2015-04-09 EC ECIEPI201513883A patent/ECSP15013883A/es unknown
- 2015-04-09 CL CL2015000902A patent/CL2015000902A1/es unknown
- 2015-04-10 MA MA37990A patent/MA37990B1/fr unknown
- 2015-06-19 US US14/744,103 patent/US9649308B2/en not_active Expired - Fee Related
-
2017
- 2017-04-05 US US15/479,972 patent/US10238654B2/en active Active
-
2018
- 2018-03-09 CY CY20181100291T patent/CY1120008T1/el unknown
- 2018-12-20 JP JP2018238486A patent/JP6632701B2/ja not_active Expired - Fee Related
-
2019
- 2019-02-25 US US16/283,929 patent/US20200054630A1/en not_active Abandoned