JP2018537093A5 - - Google Patents
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- JP2018537093A5 JP2018537093A5 JP2018526182A JP2018526182A JP2018537093A5 JP 2018537093 A5 JP2018537093 A5 JP 2018537093A5 JP 2018526182 A JP2018526182 A JP 2018526182A JP 2018526182 A JP2018526182 A JP 2018526182A JP 2018537093 A5 JP2018537093 A5 JP 2018537093A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acids
- domain
- group
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021208914A JP2022046619A (ja) | 2015-11-20 | 2021-12-23 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
| JP2024014533A JP2024032952A (ja) | 2015-11-20 | 2024-02-02 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562257883P | 2015-11-20 | 2015-11-20 | |
| US62/257,883 | 2015-11-20 | ||
| PCT/US2016/063034 WO2017087936A1 (en) | 2015-11-20 | 2016-11-21 | Compositions for treating ectopic calcification disorders, and methods using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021208914A Division JP2022046619A (ja) | 2015-11-20 | 2021-12-23 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018537093A JP2018537093A (ja) | 2018-12-20 |
| JP2018537093A5 true JP2018537093A5 (enExample) | 2020-01-09 |
Family
ID=58719303
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018526182A Pending JP2018537093A (ja) | 2015-11-20 | 2016-11-21 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
| JP2021208914A Pending JP2022046619A (ja) | 2015-11-20 | 2021-12-23 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
| JP2024014533A Pending JP2024032952A (ja) | 2015-11-20 | 2024-02-02 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021208914A Pending JP2022046619A (ja) | 2015-11-20 | 2021-12-23 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
| JP2024014533A Pending JP2024032952A (ja) | 2015-11-20 | 2024-02-02 | 異所性石灰化障害を治療するための組成物およびそれを使用する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20180371434A1 (enExample) |
| EP (2) | EP4079322A1 (enExample) |
| JP (3) | JP2018537093A (enExample) |
| AU (2) | AU2016355715A1 (enExample) |
| CA (1) | CA3005142A1 (enExample) |
| WO (1) | WO2017087936A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107109381A (zh) * | 2014-12-19 | 2017-08-29 | 阿雷克森制药公司 | 治疗组织钙化的方法 |
| US20180371434A1 (en) | 2015-11-20 | 2018-12-27 | Yale University | Compositions for Treating Ectopic Calcification Disorders, and Methods Using Same |
| EP3471747A1 (en) | 2016-06-16 | 2019-04-24 | Alexion Pharmaceuticals, Inc. | Methods of treating myointimal proliferation |
| BR112019002355A2 (pt) | 2016-08-05 | 2019-07-16 | Yale University | composições e métodos para prevenção de acidente vascular cerebral em pacientes pediátricos com anemia falciforme |
| JP7511469B2 (ja) * | 2017-09-27 | 2024-07-05 | イノザイム ファーマ， インコーポレイテッド | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
| CA3110498A1 (en) | 2018-08-31 | 2020-03-05 | Yale University | Enpp1 polypeptides and methods of using same |
| KR20230048020A (ko) * | 2020-07-02 | 2023-04-10 | 이노자임 파마, 인코포레이티드 | 동종이식 혈관병증, 모야모야병, 모야모야 증후군 및 내막 증식을 치료하기 위한 조성물 및 방법 |
| AU2021356692A1 (en) * | 2020-10-08 | 2023-05-04 | Biomarin Pharmaceutical Inc. | Liver specific production of enpp1 or enpp3 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US5007790A (en) | 1989-04-11 | 1991-04-16 | Depomed Systems, Inc. | Sustained-release oral drug dosage form |
| US5169645A (en) | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
| ATE173159T1 (de) | 1992-03-25 | 1998-11-15 | Depomed Systems Inc | Auf hydroxyethylzellulose basierende oralen arzneidosisformen mit verzoegerter wirkstoffabgabe |
| US5582837A (en) | 1992-03-25 | 1996-12-10 | Depomed, Inc. | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| CA2179383A1 (en) | 1994-01-14 | 1995-07-20 | Ira D. Goldfine | Antagonists to insulin receptor tyrosine kinase inhibitor |
| WO1997047285A1 (en) | 1996-06-10 | 1997-12-18 | Depomed, Inc. | Gastric-retentive oral controlled drug delivery system with enhanced retention properties |
| US5972389A (en) | 1996-09-19 | 1999-10-26 | Depomed, Inc. | Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter |
| US6635280B2 (en) | 1997-06-06 | 2003-10-21 | Depomed, Inc. | Extending the duration of drug release within the stomach during the fed mode |
| ES2248908T7 (es) | 1997-06-06 | 2014-11-24 | Depomed, Inc. | Formas de dosificación de fármacos por vía oral y retención gástrica para liberación continuada de fármacos altamente solubles |
| US6043056A (en) | 1998-11-06 | 2000-03-28 | Incyte Pharmaceuticals, Inc. | Cell surface glycoproteins |
| NZ518739A (en) | 1999-11-02 | 2004-12-24 | Depomed Inc | Pharmacological inducement of the fed mode for enhanced drug administration to the stomach |
| PT1251832E (pt) | 2000-02-04 | 2007-01-31 | Depomed Inc | Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero |
| US6488962B1 (en) | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
| US6451808B1 (en) | 2000-10-17 | 2002-09-17 | Depomed, Inc. | Inhibition of emetic effect of metformin with 5-HT3 receptor antagonists |
| US7888372B2 (en) | 2001-03-23 | 2011-02-15 | National Institutes Of Health (Nih) | Compositions and methods for modulating bone mineral deposition |
| US20030191073A1 (en) * | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
| US20030031711A1 (en) | 2001-05-29 | 2003-02-13 | Fara John W. | Method of treating gastroesophageal reflux disease and nocturnal acid breakthrough |
| EP1478772A2 (en) | 2001-08-14 | 2004-11-24 | The General Hospital Corporation | Nucleic acid and amino acid sequences involved in pain |
| JP2005508358A (ja) | 2001-10-25 | 2005-03-31 | デポメド・インコーポレイテッド | 胃滞留型ロサルタン投与量を用いる治療方法 |
| CA2409552A1 (en) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
| US20030091630A1 (en) | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
| TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
| US6682759B2 (en) | 2002-02-01 | 2004-01-27 | Depomed, Inc. | Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs |
| AU2003213246A1 (en) | 2002-02-21 | 2003-09-09 | University Of Virginia Patent Foundation | Bone targeting peptides |
| EP1928551B1 (en) | 2005-06-10 | 2012-05-30 | Althea Technologies, Inc. | Methods to reduce oxalate concentration by administration of oxalate oxidase crystals |
| CA2659081C (en) | 2006-08-02 | 2018-01-16 | Altus Pharmaceuticals Inc. | Crystallized oxalate decarboxylase and use thereof |
| US20080273206A1 (en) * | 2007-04-23 | 2008-11-06 | University Of South Carolina | Biomimetic Mineralization Method and System |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| GB0803352D0 (en) | 2008-02-22 | 2008-04-02 | Ntnu Technology Transfer As | Oligopeptidic compounds and uses thereof |
| EP2545080B1 (en) * | 2010-03-12 | 2017-05-10 | Alexion Pharmaceuticals, Inc. | Npp1 fusion proteins |
| KR101772366B1 (ko) | 2011-03-11 | 2017-08-28 | 알렉시온 파마슈티칼스, 인코포레이티드 | Ｎｐｐ１ 융합 단백질 |
| US9744219B2 (en) | 2013-02-13 | 2017-08-29 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| US9587235B2 (en) | 2013-03-15 | 2017-03-07 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
| CN107109381A (zh) | 2014-12-19 | 2017-08-29 | 阿雷克森制药公司 | 治疗组织钙化的方法 |
| ES2983910T3 (es) | 2015-05-19 | 2024-10-28 | Univ Yale | Composiciones para tratar afecciones patológicas de calcificación y métodos que usan las mismas |
| US20180371434A1 (en) | 2015-11-20 | 2018-12-27 | Yale University | Compositions for Treating Ectopic Calcification Disorders, and Methods Using Same |
-
2016
- 2016-11-21 US US15/777,446 patent/US20180371434A1/en not_active Abandoned
- 2016-11-21 WO PCT/US2016/063034 patent/WO2017087936A1/en not_active Ceased
- 2016-11-21 AU AU2016355715A patent/AU2016355715A1/en not_active Abandoned
- 2016-11-21 EP EP22160246.9A patent/EP4079322A1/en active Pending
- 2016-11-21 CA CA3005142A patent/CA3005142A1/en active Pending
- 2016-11-21 EP EP16867323.4A patent/EP3377105A4/en not_active Withdrawn
- 2016-11-21 JP JP2018526182A patent/JP2018537093A/ja active Pending
-
2020
- 2020-10-20 US US17/075,398 patent/US20210032610A1/en not_active Abandoned
-
2021
- 2021-12-23 JP JP2021208914A patent/JP2022046619A/ja active Pending
-
2022
- 2022-12-19 US US18/068,256 patent/US12234489B2/en active Active
-
2023
- 2023-09-07 AU AU2023226739A patent/AU2023226739A1/en active Pending
-
2024
- 2024-02-02 JP JP2024014533A patent/JP2024032952A/ja active Pending
-
2025
- 2025-01-22 US US19/033,863 patent/US20250388882A1/en active Pending
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