JP2018536484A5 - - Google Patents
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- Publication number
- JP2018536484A5 JP2018536484A5 JP2018526903A JP2018526903A JP2018536484A5 JP 2018536484 A5 JP2018536484 A5 JP 2018536484A5 JP 2018526903 A JP2018526903 A JP 2018526903A JP 2018526903 A JP2018526903 A JP 2018526903A JP 2018536484 A5 JP2018536484 A5 JP 2018536484A5
- Authority
- JP
- Japan
- Prior art keywords
- xerogel
- hydrogel
- composition
- precursor
- rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000017 hydrogel Substances 0.000 claims 23
- 239000000203 mixture Substances 0.000 claims 22
- 239000002243 precursor Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 10
- 239000007864 aqueous solution Substances 0.000 claims 9
- 239000000243 solution Substances 0.000 claims 9
- 230000008961 swelling Effects 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 8
- 229940124597 therapeutic agent Drugs 0.000 claims 7
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 238000004132 cross linking Methods 0.000 claims 3
- 238000012377 drug delivery Methods 0.000 claims 3
- 125000003827 glycol group Chemical group 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 210000001525 retina Anatomy 0.000 claims 3
- 210000003161 choroid Anatomy 0.000 claims 2
- 229920006037 cross link polymer Polymers 0.000 claims 2
- 230000007423 decrease Effects 0.000 claims 2
- 210000003786 sclera Anatomy 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 210000004127 vitreous body Anatomy 0.000 claims 2
- 239000004037 angiogenesis inhibitor Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 210000001742 aqueous humor Anatomy 0.000 claims 1
- RITAVMQDGBJQJZ-FMIVXFBMSA-N axitinib Chemical compound CNC(=O)C1=CC=CC=C1SC1=CC=C(C(\C=C\C=2N=CC=CC=2)=NN2)C2=C1 RITAVMQDGBJQJZ-FMIVXFBMSA-N 0.000 claims 1
- 229960003005 axitinib Drugs 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 230000001851 biosynthetic effect Effects 0.000 claims 1
- 210000005252 bulbus oculi Anatomy 0.000 claims 1
- 210000000795 conjunctiva Anatomy 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 210000004087 cornea Anatomy 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 claims 1
- 239000005483 tyrosine kinase inhibitor Substances 0.000 claims 1
- 150000004917 tyrosine kinase inhibitor derivatives Chemical class 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562260068P | 2015-11-25 | 2015-11-25 | |
| US62/260,068 | 2015-11-25 | ||
| US201662319033P | 2016-04-06 | 2016-04-06 | |
| US62/319,033 | 2016-04-06 | ||
| PCT/US2016/063633 WO2017091749A1 (en) | 2015-11-25 | 2016-11-23 | Shape changing drug delivery devices and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018536484A JP2018536484A (ja) | 2018-12-13 |
| JP2018536484A5 true JP2018536484A5 (enExample) | 2020-01-09 |
Family
ID=57590829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018526903A Pending JP2018536484A (ja) | 2015-11-25 | 2016-11-23 | 形状変化する薬物送達デバイス及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10420724B2 (enExample) |
| EP (1) | EP3380077B1 (enExample) |
| JP (1) | JP2018536484A (enExample) |
| KR (1) | KR20180086468A (enExample) |
| CN (1) | CN108601725B (enExample) |
| AU (1) | AU2016361579B2 (enExample) |
| BR (1) | BR112018010671A8 (enExample) |
| CA (1) | CA3006303C (enExample) |
| IL (1) | IL259530A (enExample) |
| WO (1) | WO2017091749A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107205940A (zh) | 2014-12-15 | 2017-09-26 | 约翰霍普金斯大学 | 舒尼替尼制剂及其在治疗眼部疾病中的使用方法 |
| US9855317B2 (en) | 2015-04-27 | 2018-01-02 | Reflex Medical, Inc. | Systems and methods for sympathetic cardiopulmonary neuromodulation |
| WO2017062770A1 (en) | 2015-10-08 | 2017-04-13 | Silverberg Noah | Punctal plug and bioadhesives |
| HK1257499A1 (zh) | 2015-11-12 | 2019-10-25 | Graybug Vision, Inc. | 用於治疗的聚集性微粒 |
| CA3006303C (en) | 2015-11-25 | 2023-11-14 | Incept, Llc | Shape changing drug delivery devices and methods |
| US11246879B2 (en) | 2016-02-09 | 2022-02-15 | Tulai Therapeutics, Inc. | Methods, agents, and devices for local neuromodulation of autonomic nerves |
| CA3031761A1 (en) | 2016-06-29 | 2018-01-04 | Tulavi Therapeutics, Inc. | Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system |
| AU2017331444B2 (en) | 2016-09-23 | 2023-08-17 | Incept, Llc | Intracameral drug delivery depots |
| CN111201040A (zh) | 2017-05-10 | 2020-05-26 | 灰色视觉公司 | 用于医学疗法的缓释微粒及其悬浮液 |
| CN108744048B (zh) * | 2018-06-29 | 2020-11-13 | 重庆科技学院 | 一种可实现自卷曲的双层水凝胶及其制备方法 |
| AU2019299519B2 (en) | 2018-07-02 | 2025-03-06 | Incept Llc | Methods and devices for in situ formed nerve cap |
| US20210315587A1 (en) | 2018-07-02 | 2021-10-14 | Tulavi Therapeutics, Inc. | Methods and devices for in situ formed nerve cap with rapid release |
| EA202191310A1 (ru) * | 2018-11-09 | 2021-09-16 | ТЭРИС БАЙОМЕДИКАЛ ЭлЭлСи | Устройства доставки лекарственного средства и системы для местной доставки лекарственных средств в верхние мочевыводящие пути |
| CN109350355B (zh) * | 2018-11-30 | 2023-09-12 | 西安市第四医院 | 一种smile手术来源角膜基质透镜泪道栓及其制备方法 |
| US11523896B2 (en) | 2019-05-02 | 2022-12-13 | Kevin L. Waltz | Ocular protection ring |
| MA54325A (fr) | 2019-06-05 | 2022-05-11 | Regeneron Pharma | Dispositifs et procédés pour l'administration précise de doses |
| CN111150545A (zh) * | 2020-01-02 | 2020-05-15 | 首都医科大学附属北京同仁医院 | 一种相变降温支架及其制备方法和相变降温组合支架 |
| WO2021158968A1 (en) | 2020-02-06 | 2021-08-12 | Ocular Therapeutix, Inc. | Compositions and methods for treating ocular diseases |
| PT3884929T (pt) | 2020-03-25 | 2023-08-09 | Ocular Therapeutix Inc | Implante ocular contendo um inibidor da tirosina cinase |
| CA3177005A1 (en) | 2020-04-27 | 2021-11-04 | Michael Goldstein | Methods of treating allergic conjunctivitis |
| EP4210682B1 (en) | 2020-09-14 | 2026-03-25 | EyePoint, Inc. | Bioerodible ocular drug delivery insert and therapeutic method |
| KR102893953B1 (ko) | 2020-09-24 | 2025-12-02 | 오큘라 테라퓨틱스, 인코포레이티드 | 하이드로겔 및 사이클로스포린을 포함하는 지속 방출 생분해성 소관내 삽입체 |
| JP2023542939A (ja) | 2020-09-24 | 2023-10-12 | オキュラ セラピューティクス，インコーポレイテッド | ヒドロゲル及び活性薬剤を含む徐放性生分解性小管内挿入物 |
| TWI911436B (zh) * | 2021-04-19 | 2026-01-11 | 美商視點製藥有限公司 | 生物可侵蝕之眼用藥物遞送插入物及治療方法 |
| WO2024064359A2 (en) * | 2022-09-25 | 2024-03-28 | Albert Ludwig University Of Freiburg | Marine polysaccharide networks |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
| AU2024251447A1 (en) | 2023-04-11 | 2025-08-21 | Ocular Therapeutix, Inc. | Ocular implant comprising axitinib polymorph iv |
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| IL90193A (en) | 1989-05-04 | 1993-02-21 | Biomedical Polymers Int | Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same |
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| JP6135870B2 (ja) | 2011-05-02 | 2017-05-31 | ディーエスエム アイピー アセッツ ビー．ブイ． | 生分解性ポリマーを含む繊維 |
| RU2740680C2 (ru) | 2011-09-14 | 2021-01-19 | Форсайт Вижн5, Инк. | Глазное вкладочное устройство и способы |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| US9205150B2 (en) | 2011-12-05 | 2015-12-08 | Incept, Llc | Medical organogel processes and compositions |
| EP2911623B1 (en) | 2012-10-26 | 2019-08-14 | Forsight Vision5, Inc. | Ophthalmic system for sustained release of drug to eye |
| CN107205922A (zh) | 2014-12-10 | 2017-09-26 | 因赛普特有限责任公司 | 水凝胶药物递送植入物 |
| EP4279064A3 (en) | 2015-05-12 | 2024-02-28 | Incept, LLC | Drug delivery from hydrogels |
| AU2016297642A1 (en) | 2015-07-22 | 2018-02-15 | Incept, Llc | Coated punctal plug |
| CA3006303C (en) * | 2015-11-25 | 2023-11-14 | Incept, Llc | Shape changing drug delivery devices and methods |
-
2016
- 2016-11-23 CA CA3006303A patent/CA3006303C/en active Active
- 2016-11-23 JP JP2018526903A patent/JP2018536484A/ja active Pending
- 2016-11-23 CN CN201680078805.5A patent/CN108601725B/zh active Active
- 2016-11-23 KR KR1020187017686A patent/KR20180086468A/ko not_active Abandoned
- 2016-11-23 AU AU2016361579A patent/AU2016361579B2/en active Active
- 2016-11-23 US US15/360,430 patent/US10420724B2/en active Active
- 2016-11-23 EP EP16816493.7A patent/EP3380077B1/en active Active
- 2016-11-23 WO PCT/US2016/063633 patent/WO2017091749A1/en not_active Ceased
- 2016-11-23 BR BR112018010671A patent/BR112018010671A8/pt not_active Application Discontinuation
-
2018
- 2018-05-22 IL IL259530A patent/IL259530A/en unknown
-
2019
- 2019-08-06 US US16/533,331 patent/US10786462B2/en active Active
-
2020
- 2020-08-21 US US16/999,504 patent/US11413250B2/en active Active
-
2022
- 2022-07-07 US US17/859,820 patent/US11938223B2/en active Active
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