IL259530A - Different devices and methods for drug release - Google Patents

Different devices and methods for drug release

Info

Publication number
IL259530A
IL259530A IL259530A IL25953018A IL259530A IL 259530 A IL259530 A IL 259530A IL 259530 A IL259530 A IL 259530A IL 25953018 A IL25953018 A IL 25953018A IL 259530 A IL259530 A IL 259530A
Authority
IL
Israel
Prior art keywords
methods
drug delivery
delivery devices
shape changing
changing drug
Prior art date
Application number
IL259530A
Other languages
English (en)
Hebrew (he)
Original Assignee
Incept Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incept Llc filed Critical Incept Llc
Publication of IL259530A publication Critical patent/IL259530A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL259530A 2015-11-25 2018-05-22 Different devices and methods for drug release IL259530A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562260068P 2015-11-25 2015-11-25
US201662319033P 2016-04-06 2016-04-06
PCT/US2016/063633 WO2017091749A1 (en) 2015-11-25 2016-11-23 Shape changing drug delivery devices and methods

Publications (1)

Publication Number Publication Date
IL259530A true IL259530A (en) 2018-07-31

Family

ID=57590829

Family Applications (1)

Application Number Title Priority Date Filing Date
IL259530A IL259530A (en) 2015-11-25 2018-05-22 Different devices and methods for drug release

Country Status (10)

Country Link
US (4) US10420724B2 (enExample)
EP (1) EP3380077A1 (enExample)
JP (1) JP2018536484A (enExample)
KR (1) KR20180086468A (enExample)
CN (1) CN108601725B (enExample)
AU (1) AU2016361579B2 (enExample)
BR (1) BR112018010671A8 (enExample)
CA (1) CA3006303C (enExample)
IL (1) IL259530A (enExample)
WO (1) WO2017091749A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107278151A (zh) 2014-12-15 2017-10-20 约翰霍普金斯大学 舒尼替尼制剂及其在治疗青光眼中的使用方法
US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
BR112018009644A2 (pt) 2015-11-12 2018-11-06 Graybug Vision Inc micropartículas agregantes sólidas modificadas na superfície, material injetável, processo para preparação de micropartículas agregantes sólidas modificadas na superfície, método para tratamento de um distúrbio ocular, e, uso de micropartículas agregantes sólidas modificadas na superfície
CN108601725B (zh) 2015-11-25 2024-03-08 因赛普特有限责任公司 形状改变的药物递送装置和方法
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
WO2018005848A1 (en) 2016-06-29 2018-01-04 Bright, Corinne Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
KR102814241B1 (ko) 2016-09-23 2025-05-29 인셉트, 엘엘씨 전안방내 약물 전달 데포
CA3057875A1 (en) 2017-05-10 2018-11-15 Graybug Vision, Inc. Extended release microparticles and suspensions thereof for medical therapy
CN108744048B (zh) * 2018-06-29 2020-11-13 重庆科技学院 一种可实现自卷曲的双层水凝胶及其制备方法
US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
CA3105343A1 (en) 2018-07-02 2020-01-09 Corinne Bright Methods and devices for in situ formed nerve cap
SG11202103505YA (en) * 2018-11-09 2021-05-28 Taris Biomedical Llc Drug delivery devices and systems for local drug delivery to the upper urinary tract
CN109350355B (zh) * 2018-11-30 2023-09-12 西安市第四医院 一种smile手术来源角膜基质透镜泪道栓及其制备方法
US11523896B2 (en) 2019-05-02 2022-12-13 Kevin L. Waltz Ocular protection ring
CN111150545A (zh) * 2020-01-02 2020-05-15 首都医科大学附属北京同仁医院 一种相变降温支架及其制备方法和相变降温组合支架
EP4252776A3 (en) 2020-02-06 2023-11-22 Ocular Therapeutix, Inc. Compositions and methods for treating ocular diseases
WO2021195163A1 (en) 2020-03-25 2021-09-30 Ocular Therapeutix, Inc. Ocular implant containing a tyrosine kinase inhibitor
WO2021222117A1 (en) 2020-04-27 2021-11-04 Ocular Therapeutix, Inc. Methods of treating allergic conjunctivitis
WO2022066884A1 (en) 2020-09-24 2022-03-31 Ocular Therapeutix, Inc. Sustained release biodegradalbe intracanalicular inserts comprising a hydrogel and cyclosporine
US12161753B2 (en) 2020-09-24 2024-12-10 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent
EP4590593A2 (en) * 2022-09-25 2025-07-30 Albert-Ludwigs-Universität Freiburg Marine polysaccharide networks
EP4583930A1 (en) 2023-04-11 2025-07-16 Ocular Therapeutix, Inc. Ocular implant comprising axitinib polymorph iv

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1014335A (en) 1910-11-10 1912-01-09 Union Typewriter Co Type-writing machine.
US3640741A (en) 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
US3865108A (en) 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
DE2437629C3 (de) 1974-08-05 1978-09-21 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4207893A (en) 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4484922A (en) 1981-06-25 1984-11-27 Rosenwald Peter L Occular device
US4741872A (en) 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US5160745A (en) 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5304595A (en) 1988-11-21 1994-04-19 Collagen Corporation Collagen-polymer conjugates
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
JP3165734B2 (ja) 1992-05-19 2001-05-14 テルモ株式会社 新規な高吸水形状記憶材料
US5304959A (en) 1992-10-16 1994-04-19 Spectrian, Inc. Planar microstrip balun
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
WO1999021512A1 (en) 1997-10-27 1999-05-06 The Regents Of The University Of California Methods and pharmaceutical compositions for the closure of retinal breaks
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6152943A (en) 1998-08-14 2000-11-28 Incept Llc Methods and apparatus for intraluminal deposition of hydrogels
WO2000033764A1 (en) 1998-12-04 2000-06-15 Pathak Chandrashekhar P Biocompatible crosslinked polymers
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
DE60135352D1 (de) 2000-08-30 2008-09-25 Univ Johns Hopkins Vorrichtung zur intraokularen wirkstoffverabreichung
CA2438193A1 (en) 2001-02-26 2002-09-06 Duke University Novel dendritic polymers and their biomedical uses
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
US7129210B2 (en) 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
CN1882338A (zh) * 2003-09-18 2006-12-20 马库赛特公司 经巩膜递送
WO2006031358A2 (en) 2004-08-13 2006-03-23 Hyperbranch Medical Technology, Inc. Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses
WO2006031388A2 (en) 2004-08-20 2006-03-23 Hyperbranch Medical Technology, Inc. Dentritic polymers, crosslinked gels, and their uses in orthopedic applications
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair
WO2007005249A2 (en) 2005-06-29 2007-01-11 Hyperbranch Medical Technology, Inc. Nanoparticles and dendritic-polymer-based hydrogels comprising them
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US20080220047A1 (en) * 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels
US20080287633A1 (en) 2007-05-18 2008-11-20 Drumheller Paul D Hydrogel Materials
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
EP2396070B1 (en) * 2009-02-12 2024-12-04 Incept Llc Drug delivery through hydrogel plugs
CN102844054B (zh) 2009-12-15 2016-04-20 因赛普特有限责任公司 植入物和能生物降解的基准标记物
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
EP2699317B1 (en) 2011-04-21 2016-08-10 Mapi Pharma Limited Random pentapolymer for treatment of autoimmune diseases
WO2012150265A1 (en) * 2011-05-02 2012-11-08 Dsm Ip Assets B.V. Fiber comprising a biodegradable polymer
EP4094734A1 (en) 2011-09-14 2022-11-30 Forsight Vision5, Inc. Ocular insert apparatus
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
KR102039468B1 (ko) 2011-12-05 2019-11-01 인셉트, 엘엘씨 의료용 유기젤 방법 및 조성물
SI2911623T1 (sl) 2012-10-26 2019-12-31 Forsight Vision5, Inc. Oftalmični sistem za podaljšano sproščanje zdravila v oko
CN120501693A (zh) 2014-12-10 2025-08-19 因赛普特有限责任公司 水凝胶药物递送植入物
WO2016183296A1 (en) 2015-05-12 2016-11-17 Incept, Llc Drug delivery from hydrogels
CA2993182A1 (en) 2015-07-22 2017-01-26 Incept, Llc Coated punctal plug
CN108601725B (zh) * 2015-11-25 2024-03-08 因赛普特有限责任公司 形状改变的药物递送装置和方法

Also Published As

Publication number Publication date
EP3380077A1 (en) 2018-10-03
AU2016361579A1 (en) 2018-06-21
WO2017091749A8 (en) 2017-07-06
US20210128478A1 (en) 2021-05-06
US20220339108A1 (en) 2022-10-27
CA3006303C (en) 2023-11-14
US11413250B2 (en) 2022-08-16
BR112018010671A8 (pt) 2019-02-26
AU2016361579B2 (en) 2022-08-04
CN108601725A (zh) 2018-09-28
JP2018536484A (ja) 2018-12-13
KR20180086468A (ko) 2018-07-31
CN108601725B (zh) 2024-03-08
US10786462B2 (en) 2020-09-29
US20200030241A1 (en) 2020-01-30
WO2017091749A1 (en) 2017-06-01
CA3006303A1 (en) 2017-06-01
US20170143636A1 (en) 2017-05-25
US10420724B2 (en) 2019-09-24
BR112018010671A2 (pt) 2018-11-13
US11938223B2 (en) 2024-03-26

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