JP2018536484A - 形状変化する薬物送達デバイス及び方法 - Google Patents

形状変化する薬物送達デバイス及び方法 Download PDF

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Publication number
JP2018536484A
JP2018536484A JP2018526903A JP2018526903A JP2018536484A JP 2018536484 A JP2018536484 A JP 2018536484A JP 2018526903 A JP2018526903 A JP 2018526903A JP 2018526903 A JP2018526903 A JP 2018526903A JP 2018536484 A JP2018536484 A JP 2018536484A
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fiber
syringe
vehicle
hydrogel
precursor
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Japanese (ja)
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JP2018536484A5 (enExample
Inventor
ピーター・ジャレット
マイケル・ジェイ・マクグラス
ティモシー・エス・ジャレット
ラミ・エル−ハイエク
アンドリュー・シー・バンスレット
コートニー・エイ・ロザレス
チャールズ・ディ・ブリザード
アマルプリート・エス・ソーニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018526903A 2015-11-25 2016-11-23 形状変化する薬物送達デバイス及び方法 Pending JP2018536484A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562260068P 2015-11-25 2015-11-25
US62/260,068 2015-11-25
US201662319033P 2016-04-06 2016-04-06
US62/319,033 2016-04-06
PCT/US2016/063633 WO2017091749A1 (en) 2015-11-25 2016-11-23 Shape changing drug delivery devices and methods

Publications (2)

Publication Number Publication Date
JP2018536484A true JP2018536484A (ja) 2018-12-13
JP2018536484A5 JP2018536484A5 (enExample) 2020-01-09

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JP2018526903A Pending JP2018536484A (ja) 2015-11-25 2016-11-23 形状変化する薬物送達デバイス及び方法

Country Status (10)

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US (4) US10420724B2 (enExample)
EP (1) EP3380077A1 (enExample)
JP (1) JP2018536484A (enExample)
KR (1) KR20180086468A (enExample)
CN (1) CN108601725B (enExample)
AU (1) AU2016361579B2 (enExample)
BR (1) BR112018010671A8 (enExample)
CA (1) CA3006303C (enExample)
IL (1) IL259530A (enExample)
WO (1) WO2017091749A1 (enExample)

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US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
BR112018009644A2 (pt) 2015-11-12 2018-11-06 Graybug Vision Inc micropartículas agregantes sólidas modificadas na superfície, material injetável, processo para preparação de micropartículas agregantes sólidas modificadas na superfície, método para tratamento de um distúrbio ocular, e, uso de micropartículas agregantes sólidas modificadas na superfície
CN108601725B (zh) 2015-11-25 2024-03-08 因赛普特有限责任公司 形状改变的药物递送装置和方法
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
WO2018005848A1 (en) 2016-06-29 2018-01-04 Bright, Corinne Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
KR102814241B1 (ko) 2016-09-23 2025-05-29 인셉트, 엘엘씨 전안방내 약물 전달 데포
CA3057875A1 (en) 2017-05-10 2018-11-15 Graybug Vision, Inc. Extended release microparticles and suspensions thereof for medical therapy
CN108744048B (zh) * 2018-06-29 2020-11-13 重庆科技学院 一种可实现自卷曲的双层水凝胶及其制备方法
US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
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SG11202103505YA (en) * 2018-11-09 2021-05-28 Taris Biomedical Llc Drug delivery devices and systems for local drug delivery to the upper urinary tract
CN109350355B (zh) * 2018-11-30 2023-09-12 西安市第四医院 一种smile手术来源角膜基质透镜泪道栓及其制备方法
US11523896B2 (en) 2019-05-02 2022-12-13 Kevin L. Waltz Ocular protection ring
CN111150545A (zh) * 2020-01-02 2020-05-15 首都医科大学附属北京同仁医院 一种相变降温支架及其制备方法和相变降温组合支架
EP4252776A3 (en) 2020-02-06 2023-11-22 Ocular Therapeutix, Inc. Compositions and methods for treating ocular diseases
WO2021195163A1 (en) 2020-03-25 2021-09-30 Ocular Therapeutix, Inc. Ocular implant containing a tyrosine kinase inhibitor
WO2021222117A1 (en) 2020-04-27 2021-11-04 Ocular Therapeutix, Inc. Methods of treating allergic conjunctivitis
WO2022066884A1 (en) 2020-09-24 2022-03-31 Ocular Therapeutix, Inc. Sustained release biodegradalbe intracanalicular inserts comprising a hydrogel and cyclosporine
US12161753B2 (en) 2020-09-24 2024-12-10 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent
EP4590593A2 (en) * 2022-09-25 2025-07-30 Albert-Ludwigs-Universität Freiburg Marine polysaccharide networks
EP4583930A1 (en) 2023-04-11 2025-07-16 Ocular Therapeutix, Inc. Ocular implant comprising axitinib polymorph iv

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Also Published As

Publication number Publication date
EP3380077A1 (en) 2018-10-03
AU2016361579A1 (en) 2018-06-21
WO2017091749A8 (en) 2017-07-06
US20210128478A1 (en) 2021-05-06
US20220339108A1 (en) 2022-10-27
CA3006303C (en) 2023-11-14
US11413250B2 (en) 2022-08-16
BR112018010671A8 (pt) 2019-02-26
AU2016361579B2 (en) 2022-08-04
CN108601725A (zh) 2018-09-28
IL259530A (en) 2018-07-31
KR20180086468A (ko) 2018-07-31
CN108601725B (zh) 2024-03-08
US10786462B2 (en) 2020-09-29
US20200030241A1 (en) 2020-01-30
WO2017091749A1 (en) 2017-06-01
CA3006303A1 (en) 2017-06-01
US20170143636A1 (en) 2017-05-25
US10420724B2 (en) 2019-09-24
BR112018010671A2 (pt) 2018-11-13
US11938223B2 (en) 2024-03-26

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