CA3006303C - Shape changing drug delivery devices and methods - Google Patents

Shape changing drug delivery devices and methods Download PDF

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Publication number
CA3006303C
CA3006303C CA3006303A CA3006303A CA3006303C CA 3006303 C CA3006303 C CA 3006303C CA 3006303 A CA3006303 A CA 3006303A CA 3006303 A CA3006303 A CA 3006303A CA 3006303 C CA3006303 C CA 3006303C
Authority
CA
Canada
Prior art keywords
hydrogel
fiber
vehicle
syringe
xerogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3006303A
Other languages
English (en)
French (fr)
Other versions
CA3006303A1 (en
Inventor
Peter Jarrett
Michael J. Mcgrath
Timothy S. Jarrett
Rami EL-HAYEK
Andrew C. Vanslette
Courtney A. Rosales
Charles D. Blizzard
Amarpreet S. Sawhney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incept LLC
Original Assignee
Incept LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incept LLC filed Critical Incept LLC
Publication of CA3006303A1 publication Critical patent/CA3006303A1/en
Application granted granted Critical
Publication of CA3006303C publication Critical patent/CA3006303C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3006303A 2015-11-25 2016-11-23 Shape changing drug delivery devices and methods Active CA3006303C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562260068P 2015-11-25 2015-11-25
US62/260,068 2015-11-25
US201662319033P 2016-04-06 2016-04-06
US62/319,033 2016-04-06
PCT/US2016/063633 WO2017091749A1 (en) 2015-11-25 2016-11-23 Shape changing drug delivery devices and methods

Publications (2)

Publication Number Publication Date
CA3006303A1 CA3006303A1 (en) 2017-06-01
CA3006303C true CA3006303C (en) 2023-11-14

Family

ID=57590829

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3006303A Active CA3006303C (en) 2015-11-25 2016-11-23 Shape changing drug delivery devices and methods

Country Status (10)

Country Link
US (4) US10420724B2 (enExample)
EP (1) EP3380077B1 (enExample)
JP (1) JP2018536484A (enExample)
KR (1) KR20180086468A (enExample)
CN (1) CN108601725B (enExample)
AU (1) AU2016361579B2 (enExample)
BR (1) BR112018010671A8 (enExample)
CA (1) CA3006303C (enExample)
IL (1) IL259530A (enExample)
WO (1) WO2017091749A1 (enExample)

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US11246879B2 (en) 2016-02-09 2022-02-15 Tulai Therapeutics, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
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TWI911436B (zh) * 2021-04-19 2026-01-11 美商視點製藥有限公司 生物可侵蝕之眼用藥物遞送插入物及治療方法
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Also Published As

Publication number Publication date
KR20180086468A (ko) 2018-07-31
WO2017091749A1 (en) 2017-06-01
WO2017091749A8 (en) 2017-07-06
US11938223B2 (en) 2024-03-26
AU2016361579A1 (en) 2018-06-21
EP3380077B1 (en) 2026-02-11
US10420724B2 (en) 2019-09-24
CA3006303A1 (en) 2017-06-01
US20220339108A1 (en) 2022-10-27
CN108601725A (zh) 2018-09-28
EP3380077C0 (en) 2026-02-11
US11413250B2 (en) 2022-08-16
US10786462B2 (en) 2020-09-29
IL259530A (en) 2018-07-31
AU2016361579B2 (en) 2022-08-04
BR112018010671A8 (pt) 2019-02-26
EP3380077A1 (en) 2018-10-03
US20210128478A1 (en) 2021-05-06
BR112018010671A2 (en) 2018-11-13
JP2018536484A (ja) 2018-12-13
CN108601725B (zh) 2024-03-08
US20200030241A1 (en) 2020-01-30
US20170143636A1 (en) 2017-05-25

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Effective date: 20211122