CA3006303C - Shape changing drug delivery devices and methods - Google Patents
Shape changing drug delivery devices and methods Download PDFInfo
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- CA3006303C CA3006303C CA3006303A CA3006303A CA3006303C CA 3006303 C CA3006303 C CA 3006303C CA 3006303 A CA3006303 A CA 3006303A CA 3006303 A CA3006303 A CA 3006303A CA 3006303 C CA3006303 C CA 3006303C
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- hydrogel
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- TYFQFVWCELRYAO-UHFFFAOYSA-L suberate(2-) Chemical compound [O-]C(=O)CCCCCCC([O-])=O TYFQFVWCELRYAO-UHFFFAOYSA-L 0.000 description 1
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US62/319,033 | 2016-04-06 | ||
| PCT/US2016/063633 WO2017091749A1 (en) | 2015-11-25 | 2016-11-23 | Shape changing drug delivery devices and methods |
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| CA3006303C true CA3006303C (en) | 2023-11-14 |
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| EP4445952A3 (en) | 2014-12-15 | 2025-01-15 | The Johns Hopkins University | Sunitinib formulations and methods for use thereof in treatment of glaucoma |
| EP3288626B8 (en) | 2015-04-27 | 2025-12-10 | Tulavi Therapeutics, Inc. | Substances and compositions for use in blocking nerve regeneration |
| US11458041B2 (en) | 2015-10-08 | 2022-10-04 | Ocular Therapeutix, Inc. | Punctal plug and bioadhesives |
| SG11201803663XA (en) | 2015-11-12 | 2018-05-30 | Graybug Vision Inc | Aggregating microparticles for therapy |
| BR112018010671A8 (pt) * | 2015-11-25 | 2019-02-26 | Incept Llc | dispositivos e métodos de distribuição de fármaco com mudança de forma |
| WO2017139487A1 (en) | 2016-02-09 | 2017-08-17 | Northwind Medical, Inc. | Methods, agents, and devices for local neuromodulation of autonomic nerves |
| EP3478287A4 (en) | 2016-06-29 | 2020-04-08 | Tulavi Therapeutics, Inc. | TREATMENT OF SEPTICEMIA AND ASSOCIATED INFLAMMATORY CONDITIONS BY LOCAL NEUROMODULATION OF THE AUTONOMOUS NERVOUS SYSTEM |
| EP4197527A1 (en) | 2016-09-23 | 2023-06-21 | Incept, LLC | Intracameral drug delivery depots |
| EP3621654A4 (en) | 2017-05-10 | 2021-02-17 | Graybug Vision, Inc. | PROLONGED-RELEASE MICROPARTICLES AND SUSPENSIONS OF THESE INTENDED FOR MEDICAL THERAPY |
| CN108744048B (zh) * | 2018-06-29 | 2020-11-13 | 重庆科技学院 | 一种可实现自卷曲的双层水凝胶及其制备方法 |
| CN117598837A (zh) | 2018-07-02 | 2024-02-27 | 图拉维治疗股份有限公司 | 原位形成神经帽的方法和装置 |
| US20210315587A1 (en) | 2018-07-02 | 2021-10-14 | Tulavi Therapeutics, Inc. | Methods and devices for in situ formed nerve cap with rapid release |
| MA54171A (fr) * | 2018-11-09 | 2021-09-15 | Taris Biomedical Llc | Dispositifs et systèmes d'administration de médicament pour l'administration locale de médicament au tractus urinaire supérieur |
| CN109350355B (zh) * | 2018-11-30 | 2023-09-12 | 西安市第四医院 | 一种smile手术来源角膜基质透镜泪道栓及其制备方法 |
| US11523896B2 (en) | 2019-05-02 | 2022-12-13 | Kevin L. Waltz | Ocular protection ring |
| CN111150545A (zh) * | 2020-01-02 | 2020-05-15 | 首都医科大学附属北京同仁医院 | 一种相变降温支架及其制备方法和相变降温组合支架 |
| PT3861985T (pt) | 2020-02-06 | 2023-08-03 | Ocular Therapeutix Inc | Composições e métodos para tratar doenças oculares |
| ES2952677T3 (es) | 2020-03-25 | 2023-11-03 | Ocular Therapeutix Inc | Implante ocular que contiene un inhibidor de tirosina cinasa |
| WO2021222117A1 (en) | 2020-04-27 | 2021-11-04 | Ocular Therapeutix, Inc. | Methods of treating allergic conjunctivitis |
| DK3973952T3 (da) | 2020-09-24 | 2024-03-18 | Ocular Therapeutix Inc | Bionedbrydelige intrakanalikulære indsatser med vedvarende frigivelse omfattende en hydrogel og cyclosporin |
| JP2023542939A (ja) | 2020-09-24 | 2023-10-12 | オキュラ セラピューティクス，インコーポレイテッド | ヒドロゲル及び活性薬剤を含む徐放性生分解性小管内挿入物 |
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| CN120897764A (zh) | 2023-04-11 | 2025-11-04 | 视尔普斯眼科公司 | 包含阿西替尼多晶型物iv的眼部植入物 |
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| AU2016297642A1 (en) | 2015-07-22 | 2018-02-15 | Incept, Llc | Coated punctal plug |
| BR112018010671A8 (pt) * | 2015-11-25 | 2019-02-26 | Incept Llc | dispositivos e métodos de distribuição de fármaco com mudança de forma |
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2016
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- 2016-11-23 JP JP2018526903A patent/JP2018536484A/ja active Pending
- 2016-11-23 KR KR1020187017686A patent/KR20180086468A/ko not_active Abandoned
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- 2016-11-23 EP EP16816493.7A patent/EP3380077A1/en active Pending
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2020
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Also Published As
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| AU2016361579A1 (en) | 2018-06-21 |
| WO2017091749A1 (en) | 2017-06-01 |
| EP3380077A1 (en) | 2018-10-03 |
| IL259530A (en) | 2018-07-31 |
| US20220339108A1 (en) | 2022-10-27 |
| US20200030241A1 (en) | 2020-01-30 |
| US20210128478A1 (en) | 2021-05-06 |
| CN108601725B (zh) | 2024-03-08 |
| AU2016361579B2 (en) | 2022-08-04 |
| US11938223B2 (en) | 2024-03-26 |
| KR20180086468A (ko) | 2018-07-31 |
| CA3006303A1 (en) | 2017-06-01 |
| US10786462B2 (en) | 2020-09-29 |
| US11413250B2 (en) | 2022-08-16 |
| BR112018010671A2 (pt) | 2018-11-13 |
| WO2017091749A8 (en) | 2017-07-06 |
| BR112018010671A8 (pt) | 2019-02-26 |
| JP2018536484A (ja) | 2018-12-13 |
| US20170143636A1 (en) | 2017-05-25 |
| CN108601725A (zh) | 2018-09-28 |
| US10420724B2 (en) | 2019-09-24 |
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| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |
|
| EEER | Examination request |
Effective date: 20211122 |