JP2018535972A5 - - Google Patents
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- Publication number
- JP2018535972A5 JP2018535972A5 JP2018522651A JP2018522651A JP2018535972A5 JP 2018535972 A5 JP2018535972 A5 JP 2018535972A5 JP 2018522651 A JP2018522651 A JP 2018522651A JP 2018522651 A JP2018522651 A JP 2018522651A JP 2018535972 A5 JP2018535972 A5 JP 2018535972A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- naturally encoded
- encoded amino
- antibody
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021132397A JP7220755B2 (ja) | 2015-11-03 | 2021-08-16 | 新規な抗ｃｄ３抗体およびその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250451P | 2015-11-03 | 2015-11-03 | |
| US62/250,451 | 2015-11-03 | ||
| US201562267086P | 2015-12-14 | 2015-12-14 | |
| US62/267,086 | 2015-12-14 | ||
| US201662374693P | 2016-08-12 | 2016-08-12 | |
| US62/374,693 | 2016-08-12 | ||
| PCT/US2016/060087 WO2017079272A2 (en) | 2015-11-03 | 2016-11-02 | Anti-cd3-folate conjugates and their uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021132397A Division JP7220755B2 (ja) | 2015-11-03 | 2021-08-16 | 新規な抗ｃｄ３抗体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535972A JP2018535972A (ja) | 2018-12-06 |
| JP2018535972A5 true JP2018535972A5 (enExample) | 2019-12-12 |
| JP6931649B2 JP6931649B2 (ja) | 2021-09-08 |
Family
ID=58662682
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018522651A Active JP6931649B2 (ja) | 2015-11-03 | 2016-11-02 | 新規な抗ｃｄ３抗体およびその使用 |
| JP2021132397A Active JP7220755B2 (ja) | 2015-11-03 | 2021-08-16 | 新規な抗ｃｄ３抗体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021132397A Active JP7220755B2 (ja) | 2015-11-03 | 2021-08-16 | 新規な抗ｃｄ３抗体およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11851488B2 (enExample) |
| EP (1) | EP3370771A4 (enExample) |
| JP (2) | JP6931649B2 (enExample) |
| KR (1) | KR20180077271A (enExample) |
| CN (1) | CN108348603B (enExample) |
| AU (1) | AU2016349786C1 (enExample) |
| BR (1) | BR112018009004A8 (enExample) |
| CA (1) | CA3002573A1 (enExample) |
| IL (1) | IL258759B2 (enExample) |
| MX (1) | MX2018005232A (enExample) |
| NZ (1) | NZ743049A (enExample) |
| SG (2) | SG10201913746RA (enExample) |
| WO (1) | WO2017079272A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL274761B2 (en) * | 2017-11-22 | 2024-07-01 | Geltor Inc | Methods and systems for engineering collagen |
| US12377294B2 (en) * | 2018-08-28 | 2025-08-05 | Ambrx, Inc. | Anti-CD3 antibody folate bioconjugates and their uses |
| KR102239781B1 (ko) | 2019-04-08 | 2021-04-13 | 주식회사 녹십자 | Gpnmb 및 cd3에 특이적으로 결합하는 이중특이적 항체 및 이의 용도 |
| WO2020232165A1 (en) * | 2019-05-14 | 2020-11-19 | Qlb Biotherapeutics | Bispecific anti-cd3 x cd20 antibodies and uses thereof |
| TWI905099B (zh) | 2019-05-21 | 2025-11-21 | 瑞士商諾華公司 | Cd19 結合分子及其用途 |
| TWI888487B (zh) * | 2020-02-14 | 2025-07-01 | 日商協和麒麟股份有限公司 | 與ｃｄ３結合之雙特異性抗體 |
| TWI827807B (zh) * | 2020-02-26 | 2024-01-01 | 香港商潤俊（中國）有限公司 | 抗cd3抗體葉酸生物共軛物及其用途 |
| WO2021173889A1 (en) | 2020-02-26 | 2021-09-02 | Ambrx, Inc. | Uses of anti-cd3 antibody folate bioconjugates |
| MX2023002194A (es) | 2020-08-25 | 2023-03-03 | Gilead Sciences Inc | Moleculas multiespecificas de union a antigenos dirigidas al vih y metodos de uso. |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| FR2504010B1 (fr) | 1981-04-15 | 1985-10-25 | Sanofi Sa | Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4671958A (en) | 1982-03-09 | 1987-06-09 | Cytogen Corporation | Antibody conjugates for the delivery of compounds to target sites |
| EP0092227B1 (en) | 1982-04-19 | 1988-07-27 | Nissan Motor Co., Ltd. | Method for controlling reduction ratio of continuously variable transmission with acceleration compensation |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| DE3474511D1 (en) | 1983-11-01 | 1988-11-17 | Terumo Corp | Pharmaceutical composition containing urokinase |
| US4625014A (en) | 1984-07-10 | 1986-11-25 | Dana-Farber Cancer Institute, Inc. | Cell-delivery agent |
| US4542225A (en) | 1984-08-29 | 1985-09-17 | Dana-Farber Cancer Institute, Inc. | Acid-cleavable compound |
| US4659839A (en) | 1984-10-10 | 1987-04-21 | Mallinckrodt, Inc. | Coupling agents for radiolabeled antibody fragments |
| EP0188256B1 (en) | 1985-01-14 | 1991-08-21 | NeoRx | Metal radionuclide labeled proteins for diagnosis and therapy |
| US4680338A (en) | 1985-10-17 | 1987-07-14 | Immunomedics, Inc. | Bifunctional linker |
| US4699784A (en) | 1986-02-25 | 1987-10-13 | Center For Molecular Medicine & Immunology | Tumoricidal methotrexate-antibody conjugate |
| US4904584A (en) | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| CA2131003A1 (en) | 1992-05-26 | 1993-12-09 | Raymond G. Goodwin | Novel cytokine that binds cd30 |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| AU728657B2 (en) | 1996-03-18 | 2001-01-18 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| IL133974A0 (en) | 1997-07-14 | 2001-04-30 | Bolder Biotechnology Inc | Derivatives of growth hormone and related proteins |
| US6451986B1 (en) | 1998-06-22 | 2002-09-17 | Immunex Corporation | Site specific protein modification |
| WO2000026354A1 (en) | 1998-10-30 | 2000-05-11 | Novozymes A/S | Glycosylated proteins having reduced allergenicity |
| ES2566761T3 (es) | 2002-05-30 | 2016-04-15 | The Scripps Research Institute | Ligación de azidas y acetilenos catalizada por cobre |
| KR101171397B1 (ko) | 2003-04-17 | 2012-08-07 | 더 스크립스 리서치 인스티튜트 | 진핵 유전자 코드의 확장 |
| CA2527877A1 (en) * | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| GB0716160D0 (en) | 2007-08-17 | 2007-09-26 | Biotransformations Ltd | Materials and methods for treating cancers which express folate receptors |
| JP2012034668A (ja) | 2010-08-12 | 2012-02-23 | Tohoku Univ | ヒト型化抗ｅｇｆｒ抗体リジン置換可変領域断片及びその利用 |
| WO2012158818A2 (en) | 2011-05-16 | 2012-11-22 | Fabion Pharmaceuticals, Inc. | Multi-specific fab fusion proteins and methods of use |
| CN107827985A (zh) * | 2011-05-21 | 2018-03-23 | 宏观基因有限公司 | 能够与人和非人cd3结合的cd3结合分子 |
| EP2794658B1 (en) | 2011-12-19 | 2017-03-15 | Synimmune GmbH | Bispecific antibody molecule |
| US10968276B2 (en) | 2013-03-12 | 2021-04-06 | Xencor, Inc. | Optimized anti-CD3 variable regions |
| US20160355588A1 (en) | 2013-07-12 | 2016-12-08 | Zymeworks Inc. | Bispecific CD3 and CD19 Antigen Binding Constructs |
| EP2840091A1 (en) * | 2013-08-23 | 2015-02-25 | MacroGenics, Inc. | Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof |
| AU2015292406B2 (en) * | 2014-07-25 | 2021-03-11 | Cytomx Therapeutics, Inc | Anti-CD3 antibodies, activatable anti-CD3 antibodies, multispecific anti-CD3 antibodies, multispecific activatable anti-CD3 antibodies, and methods of using the same |
| MA43164A (fr) * | 2015-11-02 | 2018-09-12 | Janssen Pharmaceutica Nv | Anticorps anti-il1rap, molécules bispécifiques de liaison à un antigène liant il1rap et cd3 et leurs utilisations |
| BR112020021279A2 (pt) * | 2018-04-17 | 2021-04-13 | Invenra Inc. | Constructos de anticorpos trispecíficos trivalentes |
| US12377294B2 (en) * | 2018-08-28 | 2025-08-05 | Ambrx, Inc. | Anti-CD3 antibody folate bioconjugates and their uses |
| AU2020223031B2 (en) * | 2019-02-12 | 2024-08-29 | Ambrx, Inc. | Compositions containing, methods and uses of antibody-TLR agonist conjugates |
| WO2020168555A1 (zh) * | 2019-02-22 | 2020-08-27 | 武汉友芝友生物制药有限公司 | Cd3抗原结合片段及其应用 |
-
2016
- 2016-11-02 WO PCT/US2016/060087 patent/WO2017079272A2/en not_active Ceased
- 2016-11-02 CN CN201680064414.8A patent/CN108348603B/zh active Active
- 2016-11-02 AU AU2016349786A patent/AU2016349786C1/en active Active
- 2016-11-02 SG SG10201913746RA patent/SG10201913746RA/en unknown
- 2016-11-02 CA CA3002573A patent/CA3002573A1/en active Pending
- 2016-11-02 IL IL258759A patent/IL258759B2/en unknown
- 2016-11-02 NZ NZ743049A patent/NZ743049A/en unknown
- 2016-11-02 EP EP16862859.2A patent/EP3370771A4/en not_active Withdrawn
- 2016-11-02 KR KR1020187015756A patent/KR20180077271A/ko not_active Ceased
- 2016-11-02 US US15/773,167 patent/US11851488B2/en active Active
- 2016-11-02 MX MX2018005232A patent/MX2018005232A/es unknown
- 2016-11-02 BR BR112018009004A patent/BR112018009004A8/pt not_active Application Discontinuation
- 2016-11-02 JP JP2018522651A patent/JP6931649B2/ja active Active
- 2016-11-02 SG SG11201803211TA patent/SG11201803211TA/en unknown
-
2021
- 2021-08-16 JP JP2021132397A patent/JP7220755B2/ja active Active
-
2023
- 2023-11-06 US US18/503,113 patent/US20240239889A1/en active Pending
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