|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
FR2504010B1
(fr)
|
1981-04-15 |
1985-10-25 |
Sanofi Sa |
Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4671958A
(en)
|
1982-03-09 |
1987-06-09 |
Cytogen Corporation |
Antibody conjugates for the delivery of compounds to target sites
|
|
DE3377484D1
(en)
|
1982-04-19 |
1988-09-01 |
Nissan Motor |
Method for controlling reduction ratio of continuously variable transmission with acceleration compensation
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
EP0143949B1
(en)
|
1983-11-01 |
1988-10-12 |
TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION |
Pharmaceutical composition containing urokinase
|
|
US4625014A
(en)
|
1984-07-10 |
1986-11-25 |
Dana-Farber Cancer Institute, Inc. |
Cell-delivery agent
|
|
US4542225A
(en)
|
1984-08-29 |
1985-09-17 |
Dana-Farber Cancer Institute, Inc. |
Acid-cleavable compound
|
|
US4659839A
(en)
|
1984-10-10 |
1987-04-21 |
Mallinckrodt, Inc. |
Coupling agents for radiolabeled antibody fragments
|
|
ATE66469T1
(de)
|
1985-01-14 |
1991-09-15 |
Neorx Corp |
Metall-radionuklid markiertes protein fuer diagnose und therapie.
|
|
US4680338A
(en)
|
1985-10-17 |
1987-07-14 |
Immunomedics, Inc. |
Bifunctional linker
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
US4904584A
(en)
|
1987-12-23 |
1990-02-27 |
Genetics Institute, Inc. |
Site-specific homogeneous modification of polypeptides
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
ATE311895T1
(de)
|
1992-05-26 |
2005-12-15 |
Immunex Corp |
Neue zytokine die cd30 binden
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
CA2249195A1
(en)
|
1996-03-18 |
1997-09-25 |
Board Of Regents, The University Of Texas System |
Immunoglobin-like domains with increased half lives
|
|
ATE375363T1
(de)
|
1997-07-14 |
2007-10-15 |
Bolder Biotechnology Inc |
Derivate des wachstumshormons und verwandte proteine
|
|
US6451986B1
(en)
|
1998-06-22 |
2002-09-17 |
Immunex Corporation |
Site specific protein modification
|
|
CA2348822A1
(en)
|
1998-10-30 |
2000-05-11 |
Novozymes A/S |
Glycosylated proteins having reduced allergenicity
|
|
US7375234B2
(en)
|
2002-05-30 |
2008-05-20 |
The Scripps Research Institute |
Copper-catalysed ligation of azides and acetylenes
|
|
JP5642916B2
(ja)
|
2003-04-17 |
2014-12-17 |
ザ スクリプス リサーチ インスティテュート |
真核遺伝コードの拡張
|
|
JP5275566B2
(ja)
|
2003-06-18 |
2013-08-28 |
ザ スクリプス リサーチ インスティチュート |
反応性非天然アミノ酸遺伝コード付加
|
|
GB0716160D0
(en)
*
|
2007-08-17 |
2007-09-26 |
Biotransformations Ltd |
Materials and methods for treating cancers which express folate receptors
|
|
JP2012034668A
(ja)
|
2010-08-12 |
2012-02-23 |
Tohoku Univ |
ヒト型化抗ｅｇｆｒ抗体リジン置換可変領域断片及びその利用
|
|
JP6400470B2
(ja)
*
|
2011-05-16 |
2018-10-03 |
ジェネロン（シャンハイ）コーポレイション リミテッド |
多重特異性Ｆａｂ融合タンパク質および使用法
|
|
WO2012162067A2
(en)
*
|
2011-05-21 |
2012-11-29 |
Macrogenics, Inc. |
Cd3-binding molecules capable of binding to human and non-human cd3
|
|
CN104203981A
(zh)
*
|
2011-12-19 |
2014-12-10 |
合成免疫股份有限公司 |
双特异性抗体分子
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
BR112016000666A2
(pt)
*
|
2013-07-12 |
2017-10-03 |
Zymeworks Inc |
Constructos de ligação de antígeno cd3 e cd19 biespecíficos
|
|
EP2840091A1
(en)
*
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
|
CA2955947A1
(en)
*
|
2014-07-25 |
2016-01-28 |
Cytomx Therapeutics, Inc. |
Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
|
|
BR112018008908A2
(pt)
*
|
2015-11-02 |
2018-11-27 |
Janssen Pharmaceutica Nv |
anticorpos anti-il1rap, moléculas de ligação ao antígeno biespecíficas que se ligam il1rap e cd3, e seus usos
|
|
CN112384243A
(zh)
*
|
2018-04-17 |
2021-02-19 |
英温拉公司 |
三价三特异性抗体构建体
|
|
EP3844188A1
(en)
*
|
2018-08-28 |
2021-07-07 |
Ambrx, Inc. |
Anti-cd3 antibody folate bioconjugates and their uses
|
|
CN119455003A
(zh)
*
|
2019-02-12 |
2025-02-18 |
Ambrx公司 |
包含抗体-tlr激动剂缀合物的组合物、方法和用途
|
|
CA3131036A1
(en)
*
|
2019-02-22 |
2020-08-27 |
Wuhan Yzy Biopharma Co., Ltd. |
Cd3 antigen-binding fragment and application thereof
|