JP2018535952A5 - - Google Patents
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- Publication number
- JP2018535952A5 JP2018535952A5 JP2018519423A JP2018519423A JP2018535952A5 JP 2018535952 A5 JP2018535952 A5 JP 2018535952A5 JP 2018519423 A JP2018519423 A JP 2018519423A JP 2018519423 A JP2018519423 A JP 2018519423A JP 2018535952 A5 JP2018535952 A5 JP 2018535952A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- lipid
- popc
- distearoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 29
- 150000002632 lipids Chemical class 0.000 claims 10
- 239000002245 particle Substances 0.000 claims 9
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 6
- 229920001223 polyethylene glycol Polymers 0.000 claims 6
- 239000000084 colloidal system Substances 0.000 claims 4
- 229920001477 hydrophilic polymer Polymers 0.000 claims 4
- LVNGJLRDBYCPGB-LDLOPFEMSA-N (R)-1,2-distearoylphosphatidylethanolamine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[NH3+])OC(=O)CCCCCCCCCCCCCCCCC LVNGJLRDBYCPGB-LDLOPFEMSA-N 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 150000008104 phosphatidylethanolamines Chemical class 0.000 claims 2
- -1 polyhydroxyethylene stearate Polymers 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- ZGCHLAJIRWDGFE-UHFFFAOYSA-N 1-aminopropane-1,1-diol Chemical compound CCC(N)(O)O ZGCHLAJIRWDGFE-UHFFFAOYSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 1
- 208000017701 Endocrine disease Diseases 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- 229920001214 Polysorbate 60 Polymers 0.000 claims 1
- 239000013011 aqueous formulation Substances 0.000 claims 1
- 229960000182 blood factors Drugs 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 208000030172 endocrine system disease Diseases 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- 230000003054 hormonal effect Effects 0.000 claims 1
- 229940102223 injectable solution Drugs 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518172.0A GB201518172D0 (en) | 2015-10-14 | 2015-10-14 | Colloidal particles for use in medicine |
| GB1518172.0 | 2015-10-14 | ||
| PCT/EP2016/074759 WO2017064276A1 (en) | 2015-10-14 | 2016-10-14 | Colloidal particles for use in medicine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535952A JP2018535952A (ja) | 2018-12-06 |
| JP2018535952A5 true JP2018535952A5 (https=) | 2019-12-26 |
| JP7160678B2 JP7160678B2 (ja) | 2022-10-25 |
Family
ID=55131025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519423A Active JP7160678B2 (ja) | 2015-10-14 | 2016-10-14 | 医薬用コロイド粒子 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20190192664A1 (https=) |
| EP (1) | EP3362039A1 (https=) |
| JP (1) | JP7160678B2 (https=) |
| KR (1) | KR20180067616A (https=) |
| CN (1) | CN108472246A (https=) |
| AU (1) | AU2016336929B2 (https=) |
| BR (1) | BR112018007399A2 (https=) |
| CA (1) | CA3036111C (https=) |
| EA (1) | EA201890703A1 (https=) |
| GB (1) | GB201518172D0 (https=) |
| HK (1) | HK1256814A1 (https=) |
| IL (1) | IL258567B2 (https=) |
| MX (1) | MX391574B (https=) |
| SG (2) | SG11201802956RA (https=) |
| WO (1) | WO2017064276A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4055032A1 (en) * | 2019-11-07 | 2022-09-14 | The Board Of Trustees Of The University Of Illinois | Peptides and methods of treating sepsis, atherosclerosis, thrombosis, stroke, heart attack and inflammation |
| GB202111759D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles |
| GB202111758D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
| GB202111757D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| JPH09501169A (ja) | 1993-08-06 | 1997-02-04 | オパーバス ホールディング ビー ヴィ | 小胞に生体高分子物質を高度に充填する方法 |
| JP4545928B2 (ja) | 1998-04-27 | 2010-09-15 | ジリップ・ファーマ・ビー．ブイ． | 第ｖｉｉｉ因子及び中性リポソームを含有する薬学的組成物 |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| KR100758158B1 (ko) | 1999-07-14 | 2007-09-12 | 알자 코포레이션 | 중성 지질중합체 및 그를 함유하는 리포솜 조성물 |
| US20030232075A1 (en) * | 2002-05-06 | 2003-12-18 | University Of Minnesota, A Minnesota Corporation | Compositions for producing factor Xa |
| EP1633440B1 (en) * | 2003-04-15 | 2008-05-14 | Opperbas Holding B.V. | Pharmaceutical composition comprising proteins and/or polypeptides and colloidal particles |
| CN101304757A (zh) * | 2005-06-29 | 2008-11-12 | 纽约州立大学研究基金会 | 免疫原性较低的蛋白质-脂质复合物的组合物和方法 |
| MX349417B (es) | 2009-06-03 | 2017-07-28 | Charles Mayo John | Formulaciones para el tratamiento de dolor de tejido profundo. |
| BR112012003834A2 (pt) | 2009-08-21 | 2017-08-08 | Targeted Delivery Tech Limited | métodos para tratamento de distúrbios e para tratamentos de deficiências em ácidos graxos, hipertrigliceridemia ou hipercolesterolemia e pacote |
| GB201007357D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIII |
| GB201007356D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIIa |
| MY190257A (en) | 2012-04-16 | 2022-04-11 | Cantab Biopharmaceuticals Patents Ltd | Optimised subcutaneous therapeutic agents |
| EP3608308B1 (en) * | 2013-03-08 | 2021-07-21 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
-
2015
- 2015-10-14 GB GBGB1518172.0A patent/GB201518172D0/en not_active Ceased
-
2016
- 2016-10-14 EA EA201890703A patent/EA201890703A1/ru unknown
- 2016-10-14 KR KR1020187013254A patent/KR20180067616A/ko not_active Ceased
- 2016-10-14 MX MX2018004445A patent/MX391574B/es unknown
- 2016-10-14 BR BR112018007399A patent/BR112018007399A2/pt not_active Application Discontinuation
- 2016-10-14 EP EP16781807.9A patent/EP3362039A1/en active Pending
- 2016-10-14 SG SG11201802956RA patent/SG11201802956RA/en unknown
- 2016-10-14 HK HK18115899.0A patent/HK1256814A1/zh unknown
- 2016-10-14 AU AU2016336929A patent/AU2016336929B2/en not_active Ceased
- 2016-10-14 JP JP2018519423A patent/JP7160678B2/ja active Active
- 2016-10-14 US US15/768,381 patent/US20190192664A1/en not_active Abandoned
- 2016-10-14 IL IL258567A patent/IL258567B2/en unknown
- 2016-10-14 WO PCT/EP2016/074759 patent/WO2017064276A1/en not_active Ceased
- 2016-10-14 CN CN201680073237.XA patent/CN108472246A/zh active Pending
- 2016-10-14 SG SG10202010711UA patent/SG10202010711UA/en unknown
- 2016-10-14 CA CA3036111A patent/CA3036111C/en active Active
-
2020
- 2020-05-26 US US16/883,338 patent/US20210093721A1/en not_active Abandoned
-
2024
- 2024-06-24 US US18/752,365 patent/US20250170244A1/en active Pending
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