JP2018535952A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018535952A5 JP2018535952A5 JP2018519423A JP2018519423A JP2018535952A5 JP 2018535952 A5 JP2018535952 A5 JP 2018535952A5 JP 2018519423 A JP2018519423 A JP 2018519423A JP 2018519423 A JP2018519423 A JP 2018519423A JP 2018535952 A5 JP2018535952 A5 JP 2018535952A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- lipid
- popc
- distearoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 29
- 150000002632 lipids Chemical class 0.000 claims 10
- 239000002245 particle Substances 0.000 claims 9
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 6
- 229920001223 polyethylene glycol Polymers 0.000 claims 6
- 239000000084 colloidal system Substances 0.000 claims 4
- 229920001477 hydrophilic polymer Polymers 0.000 claims 4
- LVNGJLRDBYCPGB-LDLOPFEMSA-N (R)-1,2-distearoylphosphatidylethanolamine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[NH3+])OC(=O)CCCCCCCCCCCCCCCCC LVNGJLRDBYCPGB-LDLOPFEMSA-N 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 150000008104 phosphatidylethanolamines Chemical class 0.000 claims 2
- -1 polyhydroxyethylene stearate Polymers 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- ZGCHLAJIRWDGFE-UHFFFAOYSA-N 1-aminopropane-1,1-diol Chemical compound CCC(N)(O)O ZGCHLAJIRWDGFE-UHFFFAOYSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 1
- 208000017701 Endocrine disease Diseases 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- 229920001214 Polysorbate 60 Polymers 0.000 claims 1
- 239000013011 aqueous formulation Substances 0.000 claims 1
- 229960000182 blood factors Drugs 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 208000030172 endocrine system disease Diseases 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- 230000003054 hormonal effect Effects 0.000 claims 1
- 229940102223 injectable solution Drugs 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518172.0A GB201518172D0 (en) | 2015-10-14 | 2015-10-14 | Colloidal particles for use in medicine |
| GB1518172.0 | 2015-10-14 | ||
| PCT/EP2016/074759 WO2017064276A1 (en) | 2015-10-14 | 2016-10-14 | Colloidal particles for use in medicine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535952A JP2018535952A (ja) | 2018-12-06 |
| JP2018535952A5 true JP2018535952A5 (cg-RX-API-DMAC7.html) | 2019-12-26 |
| JP7160678B2 JP7160678B2 (ja) | 2022-10-25 |
Family
ID=55131025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519423A Active JP7160678B2 (ja) | 2015-10-14 | 2016-10-14 | 医薬用コロイド粒子 |
Country Status (15)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115190883A (zh) * | 2019-11-07 | 2022-10-14 | 伊利诺伊大学评议会 | 治疗脓毒症、动脉粥样硬化、血栓形成、中风、心脏病发作和炎症的肽和方法 |
| GB202111757D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
| GB202111759D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles |
| GB202111758D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| ATE179599T1 (de) | 1993-08-06 | 1999-05-15 | Opperbas Holding Bv | Verfahren zur hohen beladung von vesikeln mit biopolymeren substanzen |
| ES2233036T3 (es) | 1998-04-27 | 2005-06-01 | Opperbas Holding B.V. | Composicion farmaceutica que comprende factor viii y liposomas neutros. |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| RU2250911C2 (ru) | 1999-07-14 | 2005-04-27 | Элзэ Копэрейшн | Липосомальная композиция, нейтральный липополимер и способ увеличения времени циркуляции липосомы |
| US20070141135A1 (en) * | 2005-06-29 | 2007-06-21 | Balu-Lyer Sathy V | Compositions and methods for less immunogenic protein-lipid complexes |
| US20030232075A1 (en) * | 2002-05-06 | 2003-12-18 | University Of Minnesota, A Minnesota Corporation | Compositions for producing factor Xa |
| ATE395101T1 (de) | 2003-04-15 | 2008-05-15 | Opperbas Holding Bv | Pharmazeutische zusammensetzung, enthaltend proteine und/oder polypeptide sowie kolloidpartikel |
| EP2437726B1 (en) | 2009-06-03 | 2018-05-16 | Sequessome Technology Holdings Limited | Formulations for the treatment of deep tissue pain |
| AU2010283998B2 (en) | 2009-08-21 | 2015-01-29 | Targeted Delivery Technologies Limited | Vesicular formulations |
| GB201007356D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIIa |
| GB201007357D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIII |
| GB2516388A (en) | 2012-04-16 | 2015-01-21 | Cantab Biopharmaceuticals Patents Ltd | Optimised subcutaneous therapeutic agents |
| JP6352950B2 (ja) * | 2013-03-08 | 2018-07-04 | ノバルティス アーゲー | 活性薬物の送達のための脂質と脂質組成物 |
-
2015
- 2015-10-14 GB GBGB1518172.0A patent/GB201518172D0/en not_active Ceased
-
2016
- 2016-10-14 EP EP16781807.9A patent/EP3362039A1/en active Pending
- 2016-10-14 SG SG11201802956RA patent/SG11201802956RA/en unknown
- 2016-10-14 WO PCT/EP2016/074759 patent/WO2017064276A1/en not_active Ceased
- 2016-10-14 KR KR1020187013254A patent/KR20180067616A/ko not_active Ceased
- 2016-10-14 IL IL258567A patent/IL258567B2/en unknown
- 2016-10-14 JP JP2018519423A patent/JP7160678B2/ja active Active
- 2016-10-14 BR BR112018007399A patent/BR112018007399A2/pt not_active Application Discontinuation
- 2016-10-14 AU AU2016336929A patent/AU2016336929B2/en not_active Ceased
- 2016-10-14 US US15/768,381 patent/US20190192664A1/en not_active Abandoned
- 2016-10-14 MX MX2018004445A patent/MX391574B/es unknown
- 2016-10-14 SG SG10202010711UA patent/SG10202010711UA/en unknown
- 2016-10-14 CN CN201680073237.XA patent/CN108472246A/zh active Pending
- 2016-10-14 HK HK18115899.0A patent/HK1256814A1/zh unknown
- 2016-10-14 CA CA3036111A patent/CA3036111C/en active Active
- 2016-10-14 EA EA201890703A patent/EA201890703A1/ru unknown
-
2020
- 2020-05-26 US US16/883,338 patent/US20210093721A1/en not_active Abandoned
-
2024
- 2024-06-24 US US18/752,365 patent/US20250170244A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6408469B2 (ja) | ヒアルロン酸をベースとする薬物送達システム | |
| Yu et al. | Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly (lactic-co-glycolic acid) | |
| JP5702734B2 (ja) | 局所投与に好適なイミダゾキノリン（アミン）及びその誘導体を含む医薬組成物 | |
| JP2020073617A (ja) | 免疫療法のための調節粒子 | |
| CN103054794B (zh) | 难溶性药物凝胶组合物及其制备方法 | |
| TWI556838B (zh) | 治療關節炎之方法 | |
| Salzano et al. | Self-assembly nanoparticles for the delivery of bisphosphonates into tumors | |
| JP2018535952A5 (cg-RX-API-DMAC7.html) | ||
| Stillman et al. | Aluminum-based metal–organic framework nanoparticles as pulmonary vaccine adjuvants | |
| BE1022346B1 (fr) | Compositions liposomales pour une administration mucosale | |
| Karami et al. | Synthesis and characterization of a novel hydrogel based on carboxymethyl chitosan/sodium alginate with the ability to release simvastatin for chronic wound healing | |
| Zhao et al. | Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review | |
| JP2008517878A5 (cg-RX-API-DMAC7.html) | ||
| Ong et al. | Nanoparticular and other carriers to deliver lactoferrin for antimicrobial, antibiofilm and bone-regenerating effects: a review | |
| US10206886B2 (en) | Lipid nanoparticles for wound healing | |
| TW201642850A (zh) | 透明質酸奈米顆粒在製備治療於一個體中之淋巴系統中之腫瘤之藥物的用途 | |
| Vijayan et al. | Dual growth factor entrapped nanoparticle enriched alginate wafer-based delivery system for suppurating wounds | |
| Tao et al. | Liposomal stabilization using a sugar-based, PEGylated amphiphilic macromolecule | |
| Gao et al. | A rod bacterium-like magnetic polymer micelle for strongly enhancing selective accumulation and internalization of nanocarriers | |
| JP2018534244A5 (cg-RX-API-DMAC7.html) | ||
| JP2017531659A5 (cg-RX-API-DMAC7.html) | ||
| HRP20230985T1 (hr) | Farmaceutske formulacije pegiliranih liposoma i faktora koagulacije krvi | |
| JP2009161460A (ja) | 乳化性製剤 | |
| US11191853B2 (en) | Post-surgical imaging marker | |
| JP2010503689A5 (cg-RX-API-DMAC7.html) |