JP2018535696A5 - - Google Patents

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Publication number
JP2018535696A5
JP2018535696A5 JP2018540229A JP2018540229A JP2018535696A5 JP 2018535696 A5 JP2018535696 A5 JP 2018535696A5 JP 2018540229 A JP2018540229 A JP 2018540229A JP 2018540229 A JP2018540229 A JP 2018540229A JP 2018535696 A5 JP2018535696 A5 JP 2018535696A5
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JP
Japan
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seq
sequence
represented
fragment
optionally
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JP2018540229A
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English (en)
Japanese (ja)
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JP7073264B2 (ja
JP2018535696A (ja
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Priority claimed from GB1518911.1A external-priority patent/GB2547179A/en
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Priority to JP2022078299A priority Critical patent/JP7503590B2/ja
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JP2018540229A 2015-10-26 2016-10-25 遺伝子構築物 Active JP7073264B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022078299A JP7503590B2 (ja) 2015-10-26 2022-05-11 遺伝子構築物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1518911.1 2015-10-26
GB1518911.1A GB2547179A (en) 2015-10-26 2015-10-26 Genetic construct
PCT/GB2016/053319 WO2017072498A1 (en) 2015-10-26 2016-10-25 Genetic construct

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022078299A Division JP7503590B2 (ja) 2015-10-26 2022-05-11 遺伝子構築物

Publications (3)

Publication Number Publication Date
JP2018535696A JP2018535696A (ja) 2018-12-06
JP2018535696A5 true JP2018535696A5 (enExample) 2019-11-21
JP7073264B2 JP7073264B2 (ja) 2022-05-23

Family

ID=55130230

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018540229A Active JP7073264B2 (ja) 2015-10-26 2016-10-25 遺伝子構築物
JP2022078299A Active JP7503590B2 (ja) 2015-10-26 2022-05-11 遺伝子構築物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022078299A Active JP7503590B2 (ja) 2015-10-26 2022-05-11 遺伝子構築物

Country Status (21)

Country Link
US (2) US10342880B2 (enExample)
EP (2) EP3985119A1 (enExample)
JP (2) JP7073264B2 (enExample)
KR (1) KR102819739B1 (enExample)
CN (1) CN108350467B (enExample)
AU (1) AU2016344508B2 (enExample)
CY (1) CY1124588T1 (enExample)
DK (1) DK3368678T3 (enExample)
ES (1) ES2886009T3 (enExample)
GB (1) GB2547179A (enExample)
HR (1) HRP20211407T1 (enExample)
HU (1) HUE056911T2 (enExample)
LT (1) LT3368678T (enExample)
MX (1) MX2018005286A (enExample)
PL (1) PL3368678T3 (enExample)
PT (1) PT3368678T (enExample)
RS (1) RS62460B1 (enExample)
RU (1) RU2734678C2 (enExample)
SI (1) SI3368678T1 (enExample)
SM (1) SMT202100520T1 (enExample)
WO (1) WO2017072498A1 (enExample)

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CA2999279A1 (en) 2015-10-01 2017-04-06 Goleini Inc. Targeted expression of chloride channels and methods of use thereof
GB201705484D0 (en) * 2017-04-05 2017-05-17 Quethera Ltd Genetic construct
KR20200057051A (ko) * 2017-09-27 2020-05-25 시질론 테라퓨틱스, 인크. 활성 세포를 포함하는 방법, 조성물 및 이식 가능한 요소
MX2020004035A (es) 2017-10-20 2020-11-09 Res Inst Nationwide Childrens Hospital Métodos y materiales para terapia génica con nt-3.
JP2021507723A (ja) * 2017-12-05 2021-02-25 ユニバーシティ オブ ワシントンUniversity of Washington 視細胞における治療遺伝子の機能的発現を増強するための組成物および方法
CN108250288A (zh) * 2018-01-17 2018-07-06 吉林省农业科学院 一种叶绿体表达的脑源性神经营养因子hBDNFb蛋白及其制备方法
CN109022487A (zh) * 2018-08-15 2018-12-18 上海市第人民医院 一种表达p65的基因载体及其用于治疗视网膜神经节细胞变性的基因治疗药物
US12534739B2 (en) 2018-10-11 2026-01-27 Decibel Therapeutics, Inc. AAV1 vectors and uses thereof for treatment of otic indications
JP2022514863A (ja) * 2018-12-19 2022-02-16 ヴェルサメブ アーゲー タンパク質をコードするrna
WO2020179844A1 (ja) * 2019-03-04 2020-09-10 公益財団法人東京都医学総合研究所 Trk断片をコードする核酸構築物、及びその利用
SG11202108864UA (en) * 2019-03-06 2021-09-29 Generation Bio Co Closed-ended dna (cedna) and immune modulating compounds
US12649930B2 (en) 2019-03-27 2026-06-09 Sigilon Therapeutics, Inc. Compositions, devices, and methods for treating Fabry disease
CA3133357A1 (en) * 2019-03-27 2020-10-01 Sigilon Therapeutics, Inc. Compositions, devices and methods for factor vii therapy
US20230038502A1 (en) 2019-06-11 2023-02-09 Shire Human Genetic Therapies, Inc. Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein
WO2021011841A1 (en) * 2019-07-18 2021-01-21 Lysogene Compositions and methods for the treatment of sanfilippo disease and other disorders
RU2719013C1 (ru) * 2019-09-25 2020-04-16 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Генно-инженерная конструкция для стимуляции посттравматической регенерации периферических нервов
JP7713130B2 (ja) 2019-09-30 2025-07-25 イーライ リリー アンド カンパニー 遺伝性難聴の処置のためのアデノ随伴ウイルス(aav)システム
WO2021081280A1 (en) 2019-10-23 2021-04-29 Shire Human Genetic Therapies, Inc. Adeno-associated virus vectors based gene therapy for hereditary angioedema
EP4263614A1 (en) 2020-12-16 2023-10-25 Takeda Pharmaceutical Company Limited Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein
EP4297800A1 (en) * 2021-02-26 2024-01-03 Icahn School of Medicine at Mount Sinai Method for decreasing degeneration of retinal ganglion cells
CN116179495B (zh) * 2022-11-28 2025-06-06 上海恩凯细胞技术有限公司 转基因免疫细胞及其应用
CN118256562A (zh) * 2022-12-26 2024-06-28 科辉智药(深圳)新药研究中心有限公司 一种用于中枢神经系统疾病治疗的基因序列构建体及其应用
KR20250142340A (ko) 2023-02-02 2025-09-30 퀘세라 리미티드 재조합 아데노-부속 바이러스 벡터
CN118534135A (zh) * 2024-06-07 2024-08-23 中国人民解放军联勤保障部队第九二四医院 一种中枢性肥胖抵抗标志物及其检测方法和应用

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US5229500A (en) 1989-08-30 1993-07-20 Regeneron Pharmaceuticals, Inc. Brain derived neurotrophic factor
US6225282B1 (en) * 1996-01-05 2001-05-01 Genentech, Inc. Treatment of hearing impairments
WO1998016242A1 (en) * 1996-10-16 1998-04-23 Regeneron Pharmaceuticals, Inc. Method of enhancing the delivery of growth factors
AU3418199A (en) * 1998-04-20 1999-11-08 Koninklijke Nederlandse Akademie Van Wetenschappen Use of viral vectors for treatment of the injured peripheral and central nervoussystem
DK1343532T3 (da) * 2000-12-19 2013-07-29 Res Dev Foundation Lentivirusvektormedieret genoverførsel og anvendelser deraf
US7060429B2 (en) * 2001-02-22 2006-06-13 University Of Maryland, Baltimore Treatment of neurodegenerative diseases by altering levels of TrkB isoforms and/or TrkC isoforms
FR2906533B1 (fr) * 2006-09-28 2013-02-22 Pf Medicament Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations
CA2701189C (en) * 2007-10-11 2017-05-16 Biogen Idec Ma Inc. Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists
US9265843B2 (en) * 2008-03-27 2016-02-23 The Ohio State University Treatment of metabolic-related disorders using hypothalamic gene transfer of BDNF and compositions therefor
CN103614416B (zh) * 2013-09-30 2016-09-07 中国人民解放军第二军医大学东方肝胆外科医院 一种携带人穿膜肽p53与GM-CSF基因的重组溶瘤腺病毒及其用途

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