JP2018535207A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018535207A5 JP2018535207A5 JP2018520162A JP2018520162A JP2018535207A5 JP 2018535207 A5 JP2018535207 A5 JP 2018535207A5 JP 2018520162 A JP2018520162 A JP 2018520162A JP 2018520162 A JP2018520162 A JP 2018520162A JP 2018535207 A5 JP2018535207 A5 JP 2018535207A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- sequence
- seq
- pcrv
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518668.7A GB201518668D0 (en) | 2015-10-21 | 2015-10-21 | Immunogenic Comosition |
| GB1518668.7 | 2015-10-21 | ||
| PCT/EP2016/075048 WO2017067964A1 (en) | 2015-10-21 | 2016-10-19 | P. aeruginosa pcrv-linked antigen vaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535207A JP2018535207A (ja) | 2018-11-29 |
| JP2018535207A5 true JP2018535207A5 (enExample) | 2019-09-26 |
| JP6998866B2 JP6998866B2 (ja) | 2022-02-04 |
Family
ID=55131414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520162A Expired - Fee Related JP6998866B2 (ja) | 2015-10-21 | 2016-10-19 | 緑膿菌ＰｃｒＶ連結型抗原ワクチン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11406696B2 (enExample) |
| EP (1) | EP3365004A1 (enExample) |
| JP (1) | JP6998866B2 (enExample) |
| CN (1) | CN108778322B (enExample) |
| BE (1) | BE1024361B1 (enExample) |
| BR (1) | BR112018007960A2 (enExample) |
| CA (1) | CA3002117A1 (enExample) |
| GB (1) | GB201518668D0 (enExample) |
| MX (1) | MX2018004938A (enExample) |
| WO (1) | WO2017067964A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7551618B2 (ja) | 2018-12-12 | 2024-09-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Ｏ－結合型グリコシル化のための修飾キャリアタンパク質 |
| CA3128027A1 (en) * | 2019-01-29 | 2020-08-06 | Shire-Nps Pharmaceuticals, Inc. | Parathyroid hormone variants |
| IL286467B1 (en) | 2019-03-18 | 2025-10-01 | Janssen Pharmaceuticals Inc | Methods for producing bioconjugates of E. COLI O-antigen polysaccharides, preparations thereof and methods for using them |
| UY38616A (es) | 2019-03-18 | 2020-09-30 | Janssen Pharmaceuticals Inc | Bioconjugados de polisacáridos del antígeno-o de e. coli y métodos de producción y de uso de los mismos. |
| EP3770269A1 (en) * | 2019-07-23 | 2021-01-27 | GlaxoSmithKline Biologicals S.A. | Quantification of bioconjugate glycosylation |
| US11167019B2 (en) * | 2019-12-13 | 2021-11-09 | Albany Medical College | Self-adjuvanting yersinia outer membrane vesicle as a vaccine against plague, anthrax and pseudomonas infection |
| CN111019000B (zh) * | 2019-12-28 | 2023-03-28 | 重庆艾力彼生物科技有限公司 | 铜绿假单胞菌疫苗重组蛋白reFPO及制备方法和应用 |
| US20230241197A1 (en) * | 2020-05-27 | 2023-08-03 | Kyoto Prefectural Public University Corporation | Protein molecule useful for anti-pseudomonas aeruginosa vaccine |
| EP4168040A1 (en) | 2020-06-18 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Shigella-tetravalent (shigella4v) bioconjugate |
| IL301248B2 (en) | 2020-09-17 | 2024-04-01 | Janssen Pharmaceuticals Inc | Multivalent vaccine compositions and uses thereof |
| WO2022214620A1 (en) | 2021-04-08 | 2022-10-13 | Janssen Pharmaceuticals, Inc. | Process for bioconjugate production |
| WO2023236041A1 (zh) * | 2022-06-07 | 2023-12-14 | 南方科技大学 | 编码PcrV和/或OprF-I蛋白的mRNA疫苗 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| SK279188B6 (sk) | 1992-06-25 | 1998-07-08 | Smithkline Beecham Biologicals S.A. | Vakcínová kompozícia spôsob jej prípravy a použiti |
| ES2162139T5 (es) | 1993-03-23 | 2008-05-16 | Smithkline Beecham Biologicals S.A. | Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado. |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| CA2560114A1 (en) | 1994-07-15 | 1996-02-01 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| EP0717106B1 (en) | 1994-12-16 | 2000-03-15 | Chiron Behring Gmbh & Co. | Immunogenic hybrid protein OprF-Oprl derived from Pseudomonas aeruginosa membrane proteins |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| WO1999011241A1 (en) | 1997-09-05 | 1999-03-11 | Smithkline Beecham Biologicals S.A. | Oil in water emulsions containing saponins |
| KR100947757B1 (ko) | 2001-01-23 | 2010-03-18 | 아벤티스 파스퇴르 | 다가 수막구균 폴리사카라이드―단백질 접합체 백신 |
| CN101360831B (zh) * | 2005-05-11 | 2013-07-10 | Eth苏黎世公司 | 来自原核细胞的重组n-糖基化蛋白 |
| US8063063B2 (en) | 2006-03-23 | 2011-11-22 | Novartis Ag | Immunopotentiating compounds |
| ES2536426T3 (es) | 2006-03-23 | 2015-05-25 | Novartis Ag | Compuestos de imidazoquinoxalina como inmunomoduladores |
| JP2008133206A (ja) * | 2006-11-28 | 2008-06-12 | Yokohama City Univ | 緑膿菌に対して感染防御能を誘導できる医薬組成物 |
| EP2248826B1 (en) * | 2008-01-10 | 2013-06-12 | Shionogi&Co., Ltd. | Antibody directed against pcrv |
| SG10201400320TA (en) | 2008-02-20 | 2014-05-29 | Glycovaxyn Ag | Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells |
| KR20110009158A (ko) | 2008-04-16 | 2011-01-27 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
| CA2720961A1 (en) | 2008-04-16 | 2009-10-22 | William Ripley Ballou, Jr. | Streptococcus pneumonia vaccine |
| CN102341496B (zh) * | 2009-03-11 | 2014-07-02 | 盐野义制药株式会社 | 具有抗绿脓杆菌作用的人源化PcrV抗体 |
| CN101559222A (zh) * | 2009-05-31 | 2009-10-21 | 北京绿竹生物制药有限公司 | 人用细菌多糖-蛋白结合联合疫苗 |
| WO2011062615A1 (en) | 2009-11-19 | 2011-05-26 | Glycovaxyn Ag | Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells |
| JP6339366B2 (ja) | 2010-05-06 | 2018-06-06 | グリコヴァキシン アーゲー | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
| LT2718320T (lt) * | 2011-06-10 | 2018-04-10 | Medimmune Limited | Anti-pseodomonas psl surišančios molekulės ir jų panaudojimas |
| US8932586B2 (en) | 2011-09-06 | 2015-01-13 | Intrexon Corporation | Modified forms of Pseudomonas exotoxin A |
| SG11201404532XA (en) * | 2012-03-02 | 2014-08-28 | Ablynx Nv | Pseudomonas aeruginosa pcrv binding single variable domain antibodies |
| EP2906681B1 (en) | 2012-10-12 | 2019-01-09 | GlaxoSmithKline Biologicals S.A. | Methods of host cell modification |
| ES2713166T3 (es) * | 2012-11-07 | 2019-05-20 | Glaxosmithkline Biologicals Sa | Producción de vacuna recombinante en E. coli mediante conjugación enzimática |
| LT3131577T (lt) * | 2014-04-17 | 2020-07-27 | Glaxosmithkline Biologicals S.A. | Modifikuotos ląstelės-šeimininkės ir jų naudojimas |
| CA2956188A1 (en) * | 2014-08-08 | 2016-02-11 | Glycovaxyn Ag | Modified host cells for use in bioconjugate production |
-
2015
- 2015-10-21 GB GBGB1518668.7A patent/GB201518668D0/en not_active Ceased
-
2016
- 2016-10-19 WO PCT/EP2016/075048 patent/WO2017067964A1/en not_active Ceased
- 2016-10-19 BR BR112018007960A patent/BR112018007960A2/pt not_active IP Right Cessation
- 2016-10-19 US US15/769,646 patent/US11406696B2/en active Active
- 2016-10-19 EP EP16784182.4A patent/EP3365004A1/en not_active Withdrawn
- 2016-10-19 MX MX2018004938A patent/MX2018004938A/es unknown
- 2016-10-19 JP JP2018520162A patent/JP6998866B2/ja not_active Expired - Fee Related
- 2016-10-19 BE BE2016/5783A patent/BE1024361B1/fr not_active IP Right Cessation
- 2016-10-19 CN CN201680075151.0A patent/CN108778322B/zh not_active Expired - Fee Related
- 2016-10-19 CA CA3002117A patent/CA3002117A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018535207A5 (enExample) | ||
| KR102713707B1 (ko) | 신규 다가 나노입자 기반 백신 | |
| US20240066096A1 (en) | pHLIP® peptide mediated epitope tethering at cell surfaces | |
| AU784345B2 (en) | Hepatitis B core antigen fusion proteins | |
| CN105693865B (zh) | 包含白喉毒素无毒突变体crm197或其片段的融合蛋白 | |
| US11406696B2 (en) | P aeruginosa PcrV-linked antigen vaccines | |
| CN106794237B (zh) | 经修饰的宿主细胞及其用途 | |
| JP2010512792A5 (enExample) | ||
| KR20150054800A (ko) | 변형된 항원을 포함하는 생체접합체 및 이의 용도 | |
| JP6916524B2 (ja) | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 | |
| JP7189124B2 (ja) | Ｈ．ピロリ感染の予防又は治療に関する作用物質及び方法 | |
| KR101919002B1 (ko) | 구제역 바이러스의 가용성 다가 항원단백질 및 이의 용도 | |
| Knoot et al. | A minimal sequon sufficient for O-linked glycosylation by the versatile oligosaccharyltransferase PglS | |
| JP5864556B2 (ja) | インスリン様成長因子１受容体結合ペプチド | |
| CN112501096A (zh) | 一组肠道外致病大肠杆菌糖蛋白结合疫苗的基因工程大肠杆菌的构建及应用 | |
| JP6454008B2 (ja) | 変異型シャペロニン複合体を利用した細胞内への局所的薬物送達システム用ナノカプセル | |
| JP2000505642A (ja) | 非病原性微生物の新規接着因子および特定の共生的性質について微生物をスクリーニングするためのその適用；そのような微生物と接着因子とを含む新規薬剤学的組成物および食品添加物 | |
| CN109306003B (zh) | 骨保护素的突变体蛋白及其相关产品与应用 | |
| US20240139304A1 (en) | P aeruginosa pcrv-linked antigen vaccines | |
| RU2619050C1 (ru) | Рекомбинантная плазмидная ДНК pET-15b_T1_RL, обеспечивающая синтез рекомбинантного слитого белка, состоящего из опухоль-специфического пептида и противоопухолевого пептида RL2, и рекомбинантный слитый белок, обладающий цитотоксической активностью по отношению к раковым клеткам и таргетными свойствами к опухолевой ткани | |
| CN112480262B (zh) | 一种融合蛋白及其制备与应用 | |
| CN118063571A (zh) | 一种高产肺炎克雷伯菌o2血清型纳米多糖结合疫苗的方法 | |
| TW200848426A (en) | SHIGELLA IpaB803 protein, producing method and coding nucleic acid thereof | |
| Brown | Bacteriophage Qβ: a versatile platform for Nanoengineering | |
| TW202311281A (zh) | 一種自組裝蛋白質奈米粒子及其應用 |