JP2018534306A - 創傷治癒のためのプラスミノーゲン投与計画 - Google Patents

創傷治癒のためのプラスミノーゲン投与計画 Download PDF

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Publication number
JP2018534306A
JP2018534306A JP2018524824A JP2018524824A JP2018534306A JP 2018534306 A JP2018534306 A JP 2018534306A JP 2018524824 A JP2018524824 A JP 2018524824A JP 2018524824 A JP2018524824 A JP 2018524824A JP 2018534306 A JP2018534306 A JP 2018534306A
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JP
Japan
Prior art keywords
wound
medicament
plasminogen
dose
biologically active
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JP2018524824A
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English (en)
Japanese (ja)
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JP2018534306A5 (https=
Inventor
ウルフ・ベルトヘイム
トール・ニー
ピエール・ローラン
マルタン・ロビタイユ
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Prometic Biotherapeutics Ltd
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Prometic Biotherapeutics Ltd
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Publication date
Application filed by Prometic Biotherapeutics Ltd filed Critical Prometic Biotherapeutics Ltd
Publication of JP2018534306A publication Critical patent/JP2018534306A/ja
Publication of JP2018534306A5 publication Critical patent/JP2018534306A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2018524824A 2015-11-10 2016-11-10 創傷治癒のためのプラスミノーゲン投与計画 Pending JP2018534306A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562253352P 2015-11-10 2015-11-10
US62/253,352 2015-11-10
PCT/IB2016/001606 WO2017081529A1 (en) 2015-11-10 2016-11-10 Plasminogen dosage regimen for wound healing

Publications (2)

Publication Number Publication Date
JP2018534306A true JP2018534306A (ja) 2018-11-22
JP2018534306A5 JP2018534306A5 (https=) 2019-12-19

Family

ID=57485826

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018524824A Pending JP2018534306A (ja) 2015-11-10 2016-11-10 創傷治癒のためのプラスミノーゲン投与計画

Country Status (14)

Country Link
US (1) US20180326023A1 (https=)
EP (1) EP3373957A1 (https=)
JP (1) JP2018534306A (https=)
KR (1) KR20180070708A (https=)
CN (1) CN108289934A (https=)
AU (1) AU2016352183A1 (https=)
BR (1) BR112018009476A8 (https=)
CA (1) CA3004509A1 (https=)
IL (1) IL259172A (https=)
MX (1) MX2018005876A (https=)
RU (1) RU2018121234A (https=)
TW (1) TW201722464A (https=)
WO (1) WO2017081529A1 (https=)
ZA (1) ZA201803010B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI868051B (zh) * 2017-06-23 2025-01-01 美商波麥堤克生物治療股份有限公司 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療
JP6628946B2 (ja) * 2017-12-26 2020-01-15 大太朗 福岡 増毛、頭皮若しくは皮膚の改質、創傷治癒、骨形成促進、または毛髪の改質に用いるための医薬組成物
CN116490200A (zh) * 2020-11-17 2023-07-25 泰伦基国际有限公司 一种提高ngf水平的方法和药物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020297A2 (en) * 2001-09-06 2003-03-13 Omnio Ab Method of improving wound healing
WO2009093970A1 (en) * 2008-01-22 2009-07-30 Omnio Healer Ab Method of improving wound healing
JP2018505209A (ja) * 2014-12-19 2018-02-22 プロメティック・バイオセラピューティクス・インコーポレイテッドＰｒｏＭｅｔｉｃ ＢｉｏＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラミノーゲンを含む医薬組成物及びその使用
JP2018533589A (ja) * 2015-11-03 2018-11-15 プロメティック・バイオセラピューティクス・インコーポレイテッドＰｒｏＭｅｔｉｃ ＢｉｏＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラスミノーゲン欠損症のためのプラスミノーゲン補充療法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0509438D0 (en) 2005-05-09 2005-06-15 Prometic Biosciences Ltd Affinity adsorbets for fibrinogen
EP2661493B1 (en) 2011-01-05 2016-03-30 ThromboGenics N.V. Plasminogen and plasmin variants
JP6000353B2 (ja) 2011-08-12 2016-09-28 スロンボジェニックス・ナムローゼ・フェンノートシャップＴｈｒｏｍｂｏＧｅｎｉｃｓ ＮＶ プラスミノーゲンおよびプラスミンの変異体

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020297A2 (en) * 2001-09-06 2003-03-13 Omnio Ab Method of improving wound healing
WO2009093970A1 (en) * 2008-01-22 2009-07-30 Omnio Healer Ab Method of improving wound healing
JP2018505209A (ja) * 2014-12-19 2018-02-22 プロメティック・バイオセラピューティクス・インコーポレイテッドＰｒｏＭｅｔｉｃ ＢｉｏＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラミノーゲンを含む医薬組成物及びその使用
JP2018533589A (ja) * 2015-11-03 2018-11-15 プロメティック・バイオセラピューティクス・インコーポレイテッドＰｒｏＭｅｔｉｃ ＢｉｏＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラスミノーゲン欠損症のためのプラスミノーゲン補充療法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BLOOD, 2012, VOL.119, NO.24, PP.5879-5887, JPN6020039778, ISSN: 0004517678 *

Also Published As

Publication number Publication date
MX2018005876A (es) 2018-11-09
TW201722464A (zh) 2017-07-01
CA3004509A1 (en) 2017-05-18
AU2016352183A1 (en) 2018-06-28
RU2018121234A3 (https=) 2020-03-12
EP3373957A1 (en) 2018-09-19
BR112018009476A8 (pt) 2019-02-26
BR112018009476A2 (pt) 2018-11-13
CN108289934A (zh) 2018-07-17
IL259172A (en) 2018-06-28
US20180326023A1 (en) 2018-11-15
KR20180070708A (ko) 2018-06-26
WO2017081529A1 (en) 2017-05-18
RU2018121234A (ru) 2019-12-13
ZA201803010B (en) 2019-07-31

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