RU2018121234A - Схема лечения плазминогеном для заживления раны - Google Patents
Схема лечения плазминогеном для заживления раны Download PDFInfo
- Publication number
- RU2018121234A RU2018121234A RU2018121234A RU2018121234A RU2018121234A RU 2018121234 A RU2018121234 A RU 2018121234A RU 2018121234 A RU2018121234 A RU 2018121234A RU 2018121234 A RU2018121234 A RU 2018121234A RU 2018121234 A RU2018121234 A RU 2018121234A
- Authority
- RU
- Russia
- Prior art keywords
- wound
- approximately
- dose
- plasminogen
- biologically active
- Prior art date
Links
- 102000013566 Plasminogen Human genes 0.000 title claims 23
- 108010051456 Plasminogen Proteins 0.000 title claims 23
- 230000029663 wound healing Effects 0.000 title claims 4
- 206010052428 Wound Diseases 0.000 claims 52
- 208000027418 Wounds and injury Diseases 0.000 claims 50
- 239000003814 drug Substances 0.000 claims 32
- 229940079593 drug Drugs 0.000 claims 28
- 238000002347 injection Methods 0.000 claims 12
- 239000007924 injection Substances 0.000 claims 12
- 208000025865 Ulcer Diseases 0.000 claims 6
- 231100000397 ulcer Toxicity 0.000 claims 6
- 239000000243 solution Substances 0.000 claims 5
- 206010011985 Decubitus ulcer Diseases 0.000 claims 4
- 208000004210 Pressure Ulcer Diseases 0.000 claims 4
- 230000001684 chronic effect Effects 0.000 claims 4
- 210000003141 lower extremity Anatomy 0.000 claims 4
- 230000001228 trophic effect Effects 0.000 claims 4
- 208000008960 Diabetic foot Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000001154 acute effect Effects 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 229940126601 medicinal product Drugs 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 238000011084 recovery Methods 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 206010045210 Tympanic Membrane Perforation Diseases 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000003454 tympanic membrane Anatomy 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562253352P | 2015-11-10 | 2015-11-10 | |
| US62/253,352 | 2015-11-10 | ||
| PCT/IB2016/001606 WO2017081529A1 (en) | 2015-11-10 | 2016-11-10 | Plasminogen dosage regimen for wound healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2018121234A true RU2018121234A (ru) | 2019-12-13 |
| RU2018121234A3 RU2018121234A3 (https=) | 2020-03-12 |
Family
ID=57485826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018121234A RU2018121234A (ru) | 2015-11-10 | 2016-11-10 | Схема лечения плазминогеном для заживления раны |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20180326023A1 (https=) |
| EP (1) | EP3373957A1 (https=) |
| JP (1) | JP2018534306A (https=) |
| KR (1) | KR20180070708A (https=) |
| CN (1) | CN108289934A (https=) |
| AU (1) | AU2016352183A1 (https=) |
| BR (1) | BR112018009476A8 (https=) |
| CA (1) | CA3004509A1 (https=) |
| IL (1) | IL259172A (https=) |
| MX (1) | MX2018005876A (https=) |
| RU (1) | RU2018121234A (https=) |
| TW (1) | TW201722464A (https=) |
| WO (1) | WO2017081529A1 (https=) |
| ZA (1) | ZA201803010B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI868051B (zh) * | 2017-06-23 | 2025-01-01 | 美商波麥堤克生物治療股份有限公司 | 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療 |
| CN111050763B (zh) * | 2017-12-26 | 2024-10-11 | 福冈大太朗 | 用于増毛、头皮或皮肤的改质、创伤治愈、骨形成促进或毛发的改质的药物组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067492B2 (en) * | 2001-09-06 | 2006-06-27 | Omnio Ab | Method of promoting healing of a tympanic membrane perforation |
| GB0509438D0 (en) | 2005-05-09 | 2005-06-15 | Prometic Biosciences Ltd | Affinity adsorbets for fibrinogen |
| WO2009093970A1 (en) * | 2008-01-22 | 2009-07-30 | Omnio Healer Ab | Method of improving wound healing |
| JP6085568B2 (ja) | 2011-01-05 | 2017-02-22 | スロンボジェニックス・ナムローゼ・フェンノートシャップＴｈｒｏｍｂｏＧｅｎｉｃｓ ＮＶ | プラスミノーゲンおよびプラスミンの変異体 |
| US9644196B2 (en) | 2011-08-12 | 2017-05-09 | Thrombogenics Nv | Plasminogen and plasmin variants |
| PY1577621A (es) * | 2014-12-19 | 2017-10-02 | Prometic Biotherapeutics Inc | Composicion farmaceutica que comprende plasminogeno y uso para el mismo |
| TWI801331B (zh) * | 2015-11-03 | 2023-05-11 | 美商波麥堤克生物治療股份有限公司 | 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法 |
-
2016
- 2016-11-09 TW TW105136489A patent/TW201722464A/zh unknown
- 2016-11-10 US US15/774,155 patent/US20180326023A1/en not_active Abandoned
- 2016-11-10 WO PCT/IB2016/001606 patent/WO2017081529A1/en not_active Ceased
- 2016-11-10 JP JP2018524824A patent/JP2018534306A/ja active Pending
- 2016-11-10 RU RU2018121234A patent/RU2018121234A/ru not_active Application Discontinuation
- 2016-11-10 MX MX2018005876A patent/MX2018005876A/es unknown
- 2016-11-10 KR KR1020187016082A patent/KR20180070708A/ko not_active Withdrawn
- 2016-11-10 CA CA3004509A patent/CA3004509A1/en not_active Abandoned
- 2016-11-10 EP EP16806278.4A patent/EP3373957A1/en not_active Withdrawn
- 2016-11-10 BR BR112018009476A patent/BR112018009476A8/pt not_active Application Discontinuation
- 2016-11-10 CN CN201680065255.3A patent/CN108289934A/zh active Pending
- 2016-11-10 AU AU2016352183A patent/AU2016352183A1/en not_active Abandoned
-
2018
- 2018-05-06 IL IL259172A patent/IL259172A/en unknown
- 2018-05-08 ZA ZA2018/03010A patent/ZA201803010B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017081529A1 (en) | 2017-05-18 |
| ZA201803010B (en) | 2019-07-31 |
| JP2018534306A (ja) | 2018-11-22 |
| BR112018009476A2 (pt) | 2018-11-13 |
| US20180326023A1 (en) | 2018-11-15 |
| CA3004509A1 (en) | 2017-05-18 |
| AU2016352183A1 (en) | 2018-06-28 |
| IL259172A (en) | 2018-06-28 |
| KR20180070708A (ko) | 2018-06-26 |
| MX2018005876A (es) | 2018-11-09 |
| EP3373957A1 (en) | 2018-09-19 |
| RU2018121234A3 (https=) | 2020-03-12 |
| BR112018009476A8 (pt) | 2019-02-26 |
| TW201722464A (zh) | 2017-07-01 |
| CN108289934A (zh) | 2018-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20200922 |