MX2018005876A - Regimen de dosificacion de plasminogeno para la cicatrizacion de heridas. - Google Patents

Regimen de dosificacion de plasminogeno para la cicatrizacion de heridas.

Info

Publication number
MX2018005876A
MX2018005876A MX2018005876A MX2018005876A MX2018005876A MX 2018005876 A MX2018005876 A MX 2018005876A MX 2018005876 A MX2018005876 A MX 2018005876A MX 2018005876 A MX2018005876 A MX 2018005876A MX 2018005876 A MX2018005876 A MX 2018005876A
Authority
MX
Mexico
Prior art keywords
plasminogen
wound healing
dosage regimen
dose
once
Prior art date
Application number
MX2018005876A
Other languages
English (en)
Inventor
Bertheim Ulf
Ny Tor
Laurin Pierre
Robitaille Martin
Original Assignee
Prometic Biotherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biotherapeutics Ltd filed Critical Prometic Biotherapeutics Ltd
Publication of MX2018005876A publication Critical patent/MX2018005876A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La invención se refiere al uso de plasminógeno o una variante biológicamente activa de este para la preparación de un medicamento para la administración local de al menos una dosis de plasminógeno o una variante biológicamente activa de este para promover la cicatrización de una herida en un sujeto. La dosis varía entre aproximadamente 2 mg y aproximadamente 30 mg. La frecuencia de la administración puede variar entre una vez al día y una vez a la semana. La invención además se refiere a medicamentos relacionados y métodos de tratamiento.
MX2018005876A 2015-11-10 2016-11-10 Regimen de dosificacion de plasminogeno para la cicatrizacion de heridas. MX2018005876A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562253352P 2015-11-10 2015-11-10
PCT/IB2016/001606 WO2017081529A1 (en) 2015-11-10 2016-11-10 Plasminogen dosage regimen for wound healing

Publications (1)

Publication Number Publication Date
MX2018005876A true MX2018005876A (es) 2018-11-09

Family

ID=57485826

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018005876A MX2018005876A (es) 2015-11-10 2016-11-10 Regimen de dosificacion de plasminogeno para la cicatrizacion de heridas.

Country Status (14)

Country Link
US (1) US20180326023A1 (es)
EP (1) EP3373957A1 (es)
JP (1) JP2018534306A (es)
KR (1) KR20180070708A (es)
CN (1) CN108289934A (es)
AU (1) AU2016352183A1 (es)
BR (1) BR112018009476A8 (es)
CA (1) CA3004509A1 (es)
IL (1) IL259172A (es)
MX (1) MX2018005876A (es)
RU (1) RU2018121234A (es)
TW (1) TW201722464A (es)
WO (1) WO2017081529A1 (es)
ZA (1) ZA201803010B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201904990A (zh) 2017-06-23 2019-02-01 美商波麥堤克生物治療股份有限公司 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療
TWI787423B (zh) 2017-12-26 2022-12-21 福岡大太朗 使用於增加毛髮、頭皮或皮膚之改質、創傷治癒、骨形成促進，或毛髮之改質的醫藥組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
GB0509438D0 (en) 2005-05-09 2005-06-15 Prometic Biosciences Ltd Affinity adsorbets for fibrinogen
WO2009093970A1 (en) * 2008-01-22 2009-07-30 Omnio Healer Ab Method of improving wound healing
WO2012093132A1 (en) 2011-01-05 2012-07-12 Thrombogenics Nv Plasminogen and plasmin variants
CN103764163A (zh) 2011-08-12 2014-04-30 斯路姆基因公司 纤溶酶原和纤溶酶变体
US10441639B2 (en) * 2014-12-19 2019-10-15 Prometic Biotherapeutics, Inc. Pharmaceutical composition comprising plasminogen and uses thereof
TWI801331B (zh) * 2015-11-03 2023-05-11 美商波麥堤克生物治療股份有限公司 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法

Also Published As

Publication number Publication date
BR112018009476A8 (pt) 2019-02-26
RU2018121234A (ru) 2019-12-13
CN108289934A (zh) 2018-07-17
AU2016352183A1 (en) 2018-06-28
CA3004509A1 (en) 2017-05-18
ZA201803010B (en) 2019-07-31
BR112018009476A2 (pt) 2018-11-13
US20180326023A1 (en) 2018-11-15
JP2018534306A (ja) 2018-11-22
WO2017081529A1 (en) 2017-05-18
IL259172A (en) 2018-06-28
RU2018121234A3 (es) 2020-03-12
TW201722464A (zh) 2017-07-01
EP3373957A1 (en) 2018-09-19
KR20180070708A (ko) 2018-06-26

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