EP3813687A4 - Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices - Google Patents
Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices Download PDFInfo
- Publication number
- EP3813687A4 EP3813687A4 EP19824845.2A EP19824845A EP3813687A4 EP 3813687 A4 EP3813687 A4 EP 3813687A4 EP 19824845 A EP19824845 A EP 19824845A EP 3813687 A4 EP3813687 A4 EP 3813687A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- thrombosis
- delivery
- treatment
- methods
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000007536 Thrombosis Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4806—Hydrolases (3) acting on peptide bonds (3.4) from animals other than mammals, e.g. snakes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21001—Chymotrypsin (3.4.21.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21004—Trypsin (3.4.21.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12036—Type of occlusion partial occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/1204—Type of occlusion temporary occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862691319P | 2018-06-28 | 2018-06-28 | |
PCT/US2019/039878 WO2020006444A1 (en) | 2018-06-28 | 2019-06-28 | Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3813687A1 EP3813687A1 (en) | 2021-05-05 |
EP3813687A4 true EP3813687A4 (en) | 2022-03-23 |
Family
ID=68985200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19824845.2A Pending EP3813687A4 (en) | 2018-06-28 | 2019-06-28 | Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP3813687A4 (en) |
JP (1) | JP2022525713A (en) |
CN (1) | CN112638289A (en) |
AU (1) | AU2019292557A1 (en) |
BR (1) | BR112021004809A2 (en) |
CA (1) | CA3110779A1 (en) |
CR (1) | CR20210059A (en) |
EA (1) | EA202190494A1 (en) |
WO (1) | WO2020006444A1 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0170115A1 (en) * | 1984-07-20 | 1986-02-05 | Kao Corporation | Thrombus dissolvent |
WO2007080515A1 (en) * | 2006-01-13 | 2007-07-19 | Aker Biomarine Asa | Thrombosis preventing krill extract |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7278094A (en) * | 1994-06-07 | 1996-01-04 | M D Serv Europe S.A. | Intravasal thrombolysis |
FR2797768B1 (en) * | 1999-09-01 | 2003-06-13 | Ifremer | USE OF A LOW MOLECULAR WEIGHT SULPHATE POLYSACCHARIDE FOR THE PRODUCTION OF A MEDICAMENT ACTIVE AGAINST VASCULAR THROMBOSIS |
EP1406641B1 (en) * | 2001-06-18 | 2009-01-07 | Neptune Technologies & Bioressources Inc. | Krill extracts for prevention and/or treatment of cardiovascular diseases |
JP2005503820A (en) * | 2001-10-01 | 2005-02-10 | ブラッドリー・エイチ・ストラウス | Use of collagenase to facilitate passage of guidewire in complete arterial occlusion |
CN1210036C (en) * | 2002-06-18 | 2005-07-13 | 蚌埠丰原医药科技发展有限公司 | Novel usage of Aspirin-DL-Lysine |
SE0303588D0 (en) * | 2003-12-30 | 2003-12-30 | Bioactive Polymers Ab C O Lund | Surface protection of exposed biological tissues |
EP1726301A1 (en) * | 2005-05-24 | 2006-11-29 | Flamel Technologies | Oral pharmaceutical composition for treating a COX-2 mediated condition |
DE102005042338B4 (en) * | 2005-09-06 | 2007-07-05 | Siemens Ag | catheter device |
EP2663335A1 (en) * | 2011-01-13 | 2013-11-20 | Medestea Internazionale S.p.A. | A composition for the regeneration of atrophic tissues |
DE202015002060U1 (en) * | 2015-03-17 | 2015-11-25 | Gerhard-Friedrich Horak | Infusion and aspiration catheter (IAC) (catheter for removal of thrombi and application of drugs) |
IL305537A (en) * | 2016-08-12 | 2023-10-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
WO2018112068A1 (en) * | 2016-12-13 | 2018-06-21 | Boston Scientific Scimed, Inc. | Thrombolysis catheter system |
-
2019
- 2019-06-28 EA EA202190494A patent/EA202190494A1/en unknown
- 2019-06-28 CN CN201980057015.2A patent/CN112638289A/en active Pending
- 2019-06-28 CR CR20210059A patent/CR20210059A/en unknown
- 2019-06-28 AU AU2019292557A patent/AU2019292557A1/en active Pending
- 2019-06-28 WO PCT/US2019/039878 patent/WO2020006444A1/en unknown
- 2019-06-28 BR BR112021004809-0A patent/BR112021004809A2/en not_active Application Discontinuation
- 2019-06-28 CA CA3110779A patent/CA3110779A1/en active Pending
- 2019-06-28 JP JP2021517700A patent/JP2022525713A/en active Pending
- 2019-06-28 EP EP19824845.2A patent/EP3813687A4/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0170115A1 (en) * | 1984-07-20 | 1986-02-05 | Kao Corporation | Thrombus dissolvent |
WO2007080515A1 (en) * | 2006-01-13 | 2007-07-19 | Aker Biomarine Asa | Thrombosis preventing krill extract |
Non-Patent Citations (1)
Title |
---|
SJODAHL JOHAN ET AL: "Characterization of proteinases from Antarctic krill (Euphausia superba)", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 26, no. 1, 1 October 2002 (2002-10-01), pages 153 - 161, XP002359070, ISSN: 1046-5928, DOI: 10.1016/S1046-5928(02)00519-3 * |
Also Published As
Publication number | Publication date |
---|---|
CA3110779A1 (en) | 2020-01-02 |
CN112638289A (en) | 2021-04-09 |
BR112021004809A2 (en) | 2021-06-22 |
AU2019292557A1 (en) | 2021-04-01 |
EA202190494A1 (en) | 2021-12-09 |
EP3813687A1 (en) | 2021-05-05 |
CR20210059A (en) | 2021-12-23 |
WO2020006444A1 (en) | 2020-01-02 |
JP2022525713A (en) | 2022-05-19 |
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STAA | Information on the status of an ep patent application or granted ep patent |
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Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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Free format text: ORIGINAL CODE: 0009012 |
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Effective date: 20210128 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20220223 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/48 20060101ALI20220217BHEP Ipc: A61K 38/26 20060101ALI20220217BHEP Ipc: A61K 31/616 20060101ALI20220217BHEP Ipc: A61M 25/10 20130101ALI20220217BHEP Ipc: A61K 38/43 20060101ALI20220217BHEP Ipc: A61B 17/12 20060101AFI20220217BHEP |
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RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MARIZYME, INC. |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
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17Q | First examination report despatched |
Effective date: 20230822 |
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P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230907 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |