JP2018533373A - 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用 - Google Patents

非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用 Download PDF

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JP2018533373A
JP2018533373A JP2018541524A JP2018541524A JP2018533373A JP 2018533373 A JP2018533373 A JP 2018533373A JP 2018541524 A JP2018541524 A JP 2018541524A JP 2018541524 A JP2018541524 A JP 2018541524A JP 2018533373 A JP2018533373 A JP 2018533373A
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cells
cell
population
human
hematopoietic
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JP2018533373A5 (enExample
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ハイデイ，エイドリアン
ヌスバウマー，オリバー
ウールフ，リチャード
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Cancer Research Technology Ltd
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Cancer Research Technology Ltd
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Priority claimed from GBGB1519198.4A external-priority patent/GB201519198D0/en
Priority claimed from GBGB1612731.8A external-priority patent/GB201612731D0/en
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Publication of JP2018533373A publication Critical patent/JP2018533373A/ja
Publication of JP2018533373A5 publication Critical patent/JP2018533373A5/ja
Priority to JP2021147372A priority Critical patent/JP7451468B2/ja
Priority to JP2024033438A priority patent/JP2024069306A/ja
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2315—Interleukin-15 (IL-15)

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JP2018541524A 2015-10-30 2016-10-31 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用 Pending JP2018533373A (ja)

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JP2021147372A JP7451468B2 (ja) 2015-10-30 2021-09-10 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用
JP2024033438A JP2024069306A (ja) 2015-10-30 2024-03-06 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1519198.4 2015-10-30
GBGB1519198.4A GB201519198D0 (en) 2015-10-30 2015-10-30 Expansion of gamma delta t cells resident in non-haematopoietic tissue and uses of these cells
GB1612731.8 2016-07-22
GBGB1612731.8A GB201612731D0 (en) 2016-07-22 2016-07-22 Expansion of non-haematopoietic tissue-resident gamma delta t cells and uses of these cells
PCT/EP2016/076264 WO2017072367A1 (en) 2015-10-30 2016-10-31 EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT γδ T CELLS AND USES OF THESE CELLS

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JP2021147372A Active JP7451468B2 (ja) 2015-10-30 2021-09-10 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用
JP2024033438A Pending JP2024069306A (ja) 2015-10-30 2024-03-06 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用

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JP2024033438A Pending JP2024069306A (ja) 2015-10-30 2024-03-06 非造血組織常在性γδ Ｔ細胞の増幅および該細胞の使用

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EP (2) EP3368658B1 (enExample)
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CN (1) CN108473958A (enExample)
AU (2) AU2016344779B2 (enExample)
CA (1) CA3003077A1 (enExample)
DK (1) DK3368658T3 (enExample)
ES (1) ES2925261T3 (enExample)
IL (3) IL295838B2 (enExample)
MX (2) MX2018005207A (enExample)
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JP2023525345A (ja) * 2020-05-12 2023-06-15 ガンマデルタ セラピューティクス リミティッド ガンマデルタｔ細胞を単離する方法
WO2023176896A1 (ja) * 2022-03-18 2023-09-21 国立大学法人長崎大学 糸状菌感染症の治療薬及び糸状菌感染症の治療方法
JP2024515064A (ja) * 2021-04-09 2024-04-04 ガンマデルタ セラピューティクス リミティッド 新規方法

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JP2022545196A (ja) 2019-08-16 2022-10-26 ガンマデルタ セラピューティクス リミテッド 抗ｔｃｒデルタ可変１抗体の治療的使用
JP7764364B2 (ja) 2019-08-16 2025-11-05 ガンマデルタ セラピューティクス リミティッド エクスビボγδ Ｔ細胞集団
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Cited By (6)

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Publication number Priority date Publication date Assignee Title
JP2023525345A (ja) * 2020-05-12 2023-06-15 ガンマデルタ セラピューティクス リミティッド ガンマデルタｔ細胞を単離する方法
JP2024515064A (ja) * 2021-04-09 2024-04-04 ガンマデルタ セラピューティクス リミティッド 新規方法
WO2023053994A1 (ja) * 2021-09-29 2023-04-06 アイ ピース， インコーポレイテッド 幹細胞の製造方法
JPWO2023053994A1 (enExample) * 2021-09-29 2023-04-06
JP7758307B2 (ja) 2021-09-29 2025-10-22 アイ ピース，インコーポレイテッド 幹細胞の製造方法
WO2023176896A1 (ja) * 2022-03-18 2023-09-21 国立大学法人長崎大学 糸状菌感染症の治療薬及び糸状菌感染症の治療方法

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US20180312808A1 (en) 2018-11-01
PH12018500926A1 (en) 2018-11-05
IL295838A (en) 2022-10-01
US20230099491A1 (en) 2023-03-30
EP4148124A1 (en) 2023-03-15
MX2018005207A (es) 2018-09-19
AU2016344779A1 (en) 2018-06-14
HK1253954A1 (en) 2019-07-05
CN108473958A (zh) 2018-08-31
US11618885B2 (en) 2023-04-04
MX2022011003A (es) 2022-10-07
WO2017072367A1 (en) 2017-05-04
IL315329A (en) 2024-10-01
IL295838B2 (en) 2025-02-01
IL258985B2 (en) 2023-02-01
KR20180098235A (ko) 2018-09-03
RU2018119684A3 (enExample) 2020-03-17
KR102821381B1 (ko) 2025-06-13
JP2024069306A (ja) 2024-05-21
JP7451468B2 (ja) 2024-03-18
EP3368658B1 (en) 2022-07-06
KR20250093576A (ko) 2025-06-24
EP3368658A1 (en) 2018-09-05
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