JP2018531961A5 - - Google Patents
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- Publication number
- JP2018531961A5 JP2018531961A5 JP2018521382A JP2018521382A JP2018531961A5 JP 2018531961 A5 JP2018531961 A5 JP 2018531961A5 JP 2018521382 A JP2018521382 A JP 2018521382A JP 2018521382 A JP2018521382 A JP 2018521382A JP 2018531961 A5 JP2018531961 A5 JP 2018531961A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- stroke
- hours
- onset
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 57
- 208000006011 Stroke Diseases 0.000 claims description 30
- 238000000034 method Methods 0.000 claims description 20
- 208000024891 symptom Diseases 0.000 claims description 19
- 208000028389 Nerve injury Diseases 0.000 claims description 15
- 230000008764 nerve damage Effects 0.000 claims description 15
- 238000011084 recovery Methods 0.000 claims description 12
- 230000001737 promoting effect Effects 0.000 claims description 9
- 239000003814 drug Substances 0.000 claims description 6
- 206010014498 Embolic stroke Diseases 0.000 claims description 4
- 206010043647 Thrombotic Stroke Diseases 0.000 claims description 4
- 230000001154 acute effect Effects 0.000 claims description 4
- 208000037906 ischaemic injury Diseases 0.000 claims description 4
- 230000000302 ischemic effect Effects 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000000926 neurological effect Effects 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 239000003112 inhibitor Substances 0.000 description 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562246574P | 2015-10-26 | 2015-10-26 | |
| US62/246,574 | 2015-10-26 | ||
| PCT/US2016/058804 WO2017075013A1 (en) | 2015-10-26 | 2016-10-26 | Methods and compositions for recovery from stroke |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531961A JP2018531961A (ja) | 2018-11-01 |
| JP2018531961A5 true JP2018531961A5 (enExample) | 2019-12-05 |
| JP6889493B2 JP6889493B2 (ja) | 2021-06-18 |
Family
ID=58631977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018521382A Active JP6889493B2 (ja) | 2015-10-26 | 2016-10-26 | 脳卒中からの回復のための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3368040B1 (enExample) |
| JP (1) | JP6889493B2 (enExample) |
| KR (1) | KR102891465B1 (enExample) |
| CN (1) | CN108348524A (enExample) |
| WO (1) | WO2017075013A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| EP3889156A4 (en) * | 2018-11-30 | 2022-07-20 | Shanghai Pharmaceuticals Holding Co., Ltd. | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ITS COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE |
| JP7384341B1 (ja) | 2023-07-07 | 2023-11-21 | 学校法人冬木学園 | 脳卒中患者の身体の痛みの改善を目的とするリハビリテーションの効果を予測するための方法、及び、システム |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6608060B1 (en) | 1996-12-18 | 2003-08-19 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US20040082509A1 (en) * | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| US7998507B2 (en) * | 2000-09-21 | 2011-08-16 | Elan Pharma International Ltd. | Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors |
| DE60319073T2 (de) * | 2002-03-20 | 2009-02-05 | Elan Pharma International Ltd. | Nanopartikelzusammensetzungen von mitogen-aktivierten protein (map) kinase inhibitoren |
| JP2005530719A (ja) * | 2002-03-29 | 2005-10-13 | ニューロジェン コーポレーション | 病原性炎症要素を有する状態の治療のための組み合わせ療法 |
| JP5627574B2 (ja) * | 2008-06-03 | 2014-11-19 | インターミューン， インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| DK179584B1 (en) | 2014-07-08 | 2019-02-20 | Halliburton Energy Services | REAL TIME CONFORMITY |
| CN106659723A (zh) * | 2014-07-09 | 2017-05-10 | 爱普制药有限责任公司 | 用于治疗神经病症的方法 |
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2016
- 2016-10-26 CN CN201680062719.5A patent/CN108348524A/zh active Pending
- 2016-10-26 WO PCT/US2016/058804 patent/WO2017075013A1/en not_active Ceased
- 2016-10-26 JP JP2018521382A patent/JP6889493B2/ja active Active
- 2016-10-26 EP EP16860660.6A patent/EP3368040B1/en active Active
- 2016-10-26 KR KR1020187012006A patent/KR102891465B1/ko active Active