JP2018530596A5 - - Google Patents
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- JP2018530596A5 JP2018530596A5 JP2018519853A JP2018519853A JP2018530596A5 JP 2018530596 A5 JP2018530596 A5 JP 2018530596A5 JP 2018519853 A JP2018519853 A JP 2018519853A JP 2018519853 A JP2018519853 A JP 2018519853A JP 2018530596 A5 JP2018530596 A5 JP 2018530596A5
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- Prior art keywords
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- Prior art date
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- 239000000203 mixture Substances 0.000 claims description 41
- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 3
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims description 3
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims description 3
- 229910052777 Praseodymium Inorganic materials 0.000 claims description 3
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims description 3
- LCKIEQZJEYYRIY-UHFFFAOYSA-N Titanium ion Chemical compound [Ti+4] LCKIEQZJEYYRIY-UHFFFAOYSA-N 0.000 claims description 3
- 229910001424 calcium ion Inorganic materials 0.000 claims description 3
- 238000005341 cation exchange Methods 0.000 claims description 3
- BUAKPNXRPHOMCG-UHFFFAOYSA-N cerium(4+) Chemical compound [Ce+4][Ce+4] BUAKPNXRPHOMCG-UHFFFAOYSA-N 0.000 claims description 3
- CULSIAXQVSZNSV-UHFFFAOYSA-N germanium(4+) Chemical compound [Ge+4] CULSIAXQVSZNSV-UHFFFAOYSA-N 0.000 claims description 3
- GVOLZAKHRKGRRM-UHFFFAOYSA-N hafnium(4+) Chemical compound [Hf+4] GVOLZAKHRKGRRM-UHFFFAOYSA-N 0.000 claims description 3
- 229910001425 magnesium ion Inorganic materials 0.000 claims description 3
- QUWPZPLTANKXAM-UHFFFAOYSA-N niobium(5+) Chemical compound [Nb+5] QUWPZPLTANKXAM-UHFFFAOYSA-N 0.000 claims description 3
- 229910001414 potassium ion Inorganic materials 0.000 claims description 3
- PUDIUYLPXJFUGB-UHFFFAOYSA-N praseodymium atom Chemical compound [Pr] PUDIUYLPXJFUGB-UHFFFAOYSA-N 0.000 claims description 3
- 229910001415 sodium ion Inorganic materials 0.000 claims description 3
- NTRPDBRJGBMHQP-UHFFFAOYSA-N terbium(4+) Chemical compound [Tb+4] NTRPDBRJGBMHQP-UHFFFAOYSA-N 0.000 claims description 3
- SYRHIZPPCHMRIT-UHFFFAOYSA-N tin(4+) Chemical compound [Sn+4] SYRHIZPPCHMRIT-UHFFFAOYSA-N 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 4
- 229910052700 potassium Inorganic materials 0.000 claims 4
- 239000011591 potassium Substances 0.000 claims 4
- 229910052708 sodium Inorganic materials 0.000 claims 4
- 239000011734 sodium Substances 0.000 claims 4
- NCMHKCKGHRPLCM-UHFFFAOYSA-N caesium(1+) Chemical compound [Cs+] NCMHKCKGHRPLCM-UHFFFAOYSA-N 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-O oxonium Chemical compound [OH3+] XLYOFNOQVPJJNP-UHFFFAOYSA-O 0.000 claims 2
- 229910001419 rubidium ion Inorganic materials 0.000 claims 2
- 208000002682 Hyperkalemia Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- -1 cesium ions Chemical class 0.000 description 2
- 229910052792 caesium Inorganic materials 0.000 description 1
- 229910001449 indium ion Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910001750 ruby Inorganic materials 0.000 description 1
- 239000010979 ruby Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/883,428 | 2015-10-14 | ||
| US14/883,428 US9592253B1 (en) | 2015-10-14 | 2015-10-14 | Extended use zirconium silicate compositions and methods of use thereof |
| PCT/US2016/056286 WO2017066128A1 (en) | 2015-10-14 | 2016-10-10 | Extended use zirconium silicate compositions and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018530596A JP2018530596A (ja) | 2018-10-18 |
| JP2018530596A5 true JP2018530596A5 (enExample) | 2019-04-04 |
| JP6546700B2 JP6546700B2 (ja) | 2019-07-17 |
Family
ID=58227650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519853A Active JP6546700B2 (ja) | 2015-10-14 | 2016-10-10 | ケイ酸ジルコニウム組成物の長期間の使用及びその使用方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9592253B1 (enExample) |
| EP (1) | EP3362456A4 (enExample) |
| JP (1) | JP6546700B2 (enExample) |
| KR (1) | KR102667566B1 (enExample) |
| CN (2) | CN113143958A (enExample) |
| AR (1) | AR106369A1 (enExample) |
| AU (1) | AU2016338753C1 (enExample) |
| CA (1) | CA3000950C (enExample) |
| CL (1) | CL2018000916A1 (enExample) |
| CR (1) | CR20180276A (enExample) |
| EA (2) | EA202091273A1 (enExample) |
| HK (1) | HK1254808A1 (enExample) |
| IL (1) | IL258478B (enExample) |
| MX (1) | MX2018004440A (enExample) |
| MY (1) | MY187088A (enExample) |
| PH (1) | PH12018500786B1 (enExample) |
| TW (1) | TWI742004B (enExample) |
| WO (1) | WO2017066128A1 (enExample) |
| ZA (1) | ZA201803095B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI2673237T4 (fi) | 2011-02-11 | 2025-12-12 | Zs Pharma Inc | Zirkoniumsilikaatin käyttö hyperkalemian hoitamiseen |
| US9592253B1 (en) * | 2015-10-14 | 2017-03-14 | ZS Pharma, Inc. | Extended use zirconium silicate compositions and methods of use thereof |
| WO2019092179A1 (en) * | 2017-11-10 | 2019-05-16 | Sandoz Ag | Pharmaceutical compositions comprising zs-9 |
| JP2022524454A (ja) | 2019-03-13 | 2022-05-02 | アストラゼネカ・アクチエボラーグ | 血液透析患者に使用するカリウム結合剤 |
| CN117342570B (zh) * | 2023-09-04 | 2026-02-10 | 杭州国瑞生物科技有限公司 | 一种环硅酸锆钠的a晶型及其制备方法 |
| CN117735564B (zh) * | 2023-12-19 | 2025-12-19 | 杭州国瑞生物科技有限公司 | 一种环硅酸锆钠的b晶型及其制备方法与应用 |
| CN120172420B (zh) * | 2025-03-21 | 2025-12-23 | 时森海(杭州)医药科技有限公司 | 控制粒径分布的环硅酸锆钠及其制备方法 |
| CN120984211A (zh) * | 2025-06-13 | 2025-11-21 | 时森海(杭州)医药科技有限公司 | 生产环硅酸锆钠的反应器和方法 |
Family Cites Families (58)
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|---|---|---|---|---|
| USRE21224E (en) | 1939-10-03 | Coherent zirconium silicates | ||
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| US3492092A (en) * | 1966-04-04 | 1970-01-27 | Chem Separations Corp | Ion exchange process for treating crude mineral solutions |
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| US4581141A (en) | 1978-02-27 | 1986-04-08 | Purdue Research Foundation | Dialysis material and method for removing uremic substances |
| FR2444005A1 (fr) | 1978-12-15 | 1980-07-11 | Ugine Kuhlmann | Procede industriel de fabrication en semi-continu de zeolithe a |
| US4943545A (en) | 1987-06-08 | 1990-07-24 | Mobil Oil Corporation | Activation of zeolites |
| US5015453A (en) | 1989-04-28 | 1991-05-14 | W. R. Grace & Co.-Conn. | Crystalline group IVA metal-containing molecular sieve compositions |
| US5099737A (en) | 1991-02-22 | 1992-03-31 | Curletto Giorgio F | Double chambered bassboard housing for electronic M.I.D.I. accordion with retractable keyboard |
| US5338527A (en) | 1992-08-20 | 1994-08-16 | Uop | Zirconium silicate composition, method of preparation and uses thereof |
| KR0169542B1 (ko) | 1992-10-28 | 1999-01-15 | 알. 브이. 타테 | 실리카 |
| US5518707A (en) | 1994-10-24 | 1996-05-21 | Uop | Metallo germanates |
| IT1283284B1 (it) | 1996-03-21 | 1998-04-16 | Eniricerche Spa | Zeolite ers-10 e procedimento per la sua preparazione |
| FR2750893B1 (fr) | 1996-07-12 | 1998-10-30 | Elf Aquitaine | Procede de synthese de zeolithe avec agitation homogene du milieu, dispositif et application |
| US5891417A (en) | 1997-04-08 | 1999-04-06 | Uop Llc | Zirconium silicate and zirconium germanate molecular sieves and process using the same |
| US5888472A (en) | 1997-04-08 | 1999-03-30 | Uop Llc | Zirconium silicate molecular sieves and process using the same |
| EP0982785A4 (en) | 1997-05-12 | 2001-04-18 | Japan Represented By Director | SEPARATOR FOR ACCUMULATOR AND ALKALI ELECTRIC ACCUMULATOR USING THE SAME |
| US6007790A (en) | 1998-08-13 | 1999-12-28 | Uop Llc | Family of microporous indium silicate compositions |
| US6099737A (en) | 1999-03-29 | 2000-08-08 | Uop Llc | Process for removing toxins from blood using zirconium metallate or titanium metallate compositions |
| US6332985B1 (en) | 1999-03-29 | 2001-12-25 | Uop Llc | Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions |
| US7041274B2 (en) | 1999-10-22 | 2006-05-09 | Intevep, S.A. | Aluminosilicate compositions, preparation and use |
| US20020061521A1 (en) | 2000-01-31 | 2002-05-23 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US6379641B1 (en) | 2000-05-01 | 2002-04-30 | Uop Llc | Microporous rare earth silicates and method of producing same |
| US6596254B1 (en) | 2000-06-12 | 2003-07-22 | Sandia Corporation | Niobate-based octahedral molecular sieves |
| WO2002062356A2 (en) | 2001-02-06 | 2002-08-15 | Ash Medical Systems, Inc. | Monovalent-selective cation exchangers as oral sorbent therapy |
| US6579460B1 (en) | 2001-03-13 | 2003-06-17 | Uop Llc | Process and composition for removing toxins from bodily fluids |
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| US6689335B1 (en) | 2002-12-19 | 2004-02-10 | Eastman Kodak Company | Silver ion sequester and release agent |
| KR100804360B1 (ko) | 2003-12-15 | 2008-02-15 | 아사히 가세이 케미칼즈 가부시키가이샤 | 다공성 성형체 및 그의 제조 방법 |
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| FI2673237T4 (fi) * | 2011-02-11 | 2025-12-12 | Zs Pharma Inc | Zirkoniumsilikaatin käyttö hyperkalemian hoitamiseen |
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| KR20150036555A (ko) * | 2012-07-11 | 2015-04-07 | 제트에스 파마, 인코포레이티드 | 고칼슘혈증 환자에서 고칼륨혈증의 치료를 위한 미세다공성 지르코늄 실리케이트 및 고칼륨혈증의 치료를 위한 개선된 칼슘-함유 조성물 |
| KR102184602B1 (ko) * | 2012-10-22 | 2020-11-30 | 제트에스 파마, 인코포레이티드 | 고칼륨혈증의 치료를 위한 미세다공성 지르코늄 실리케이트 |
| CA2908641C (en) * | 2013-04-05 | 2022-10-18 | ZS Pharma, Inc. | Microporous zirconium silicate and diuretics for the reduction of potassium and treatment of chronic kidney and/or chronic heart disease |
| MX392710B (es) * | 2013-11-08 | 2025-03-24 | Zs Pharma Inc | Silicato de zirconio microporoso para el tratamiento de la hiperpotasemia. |
| CA2933048A1 (en) * | 2013-12-10 | 2015-06-18 | ZS Pharma, Inc. | Zirconium silicate for treating hyperkalemia without co-administering lithium |
| US9592253B1 (en) * | 2015-10-14 | 2017-03-14 | ZS Pharma, Inc. | Extended use zirconium silicate compositions and methods of use thereof |
-
2015
- 2015-10-14 US US14/883,428 patent/US9592253B1/en active Active
-
2016
- 2016-10-07 TW TW105132645A patent/TWI742004B/zh active
- 2016-10-10 AU AU2016338753A patent/AU2016338753C1/en active Active
- 2016-10-10 EA EA202091273A patent/EA202091273A1/ru unknown
- 2016-10-10 WO PCT/US2016/056286 patent/WO2017066128A1/en not_active Ceased
- 2016-10-10 CR CR20180276A patent/CR20180276A/es unknown
- 2016-10-10 PH PH1/2018/500786A patent/PH12018500786B1/en unknown
- 2016-10-10 CA CA3000950A patent/CA3000950C/en active Active
- 2016-10-10 EA EA201890875A patent/EA035890B1/ru not_active IP Right Cessation
- 2016-10-10 MX MX2018004440A patent/MX2018004440A/es active IP Right Grant
- 2016-10-10 EP EP16856007.6A patent/EP3362456A4/en active Pending
- 2016-10-10 JP JP2018519853A patent/JP6546700B2/ja active Active
- 2016-10-10 MY MYPI2018701456A patent/MY187088A/en unknown
- 2016-10-10 HK HK18113894.0A patent/HK1254808A1/zh unknown
- 2016-10-10 CN CN202110531403.9A patent/CN113143958A/zh active Pending
- 2016-10-10 CN CN201680059460.9A patent/CN108137620B/zh active Active
- 2016-10-10 KR KR1020187013243A patent/KR102667566B1/ko active Active
- 2016-10-14 AR ARP160103150A patent/AR106369A1/es active IP Right Grant
-
2017
- 2017-01-31 US US15/421,132 patent/US10300087B2/en active Active
-
2018
- 2018-04-01 IL IL258478A patent/IL258478B/en active IP Right Grant
- 2018-04-10 CL CL2018000916A patent/CL2018000916A1/es unknown
- 2018-05-11 ZA ZA201803095A patent/ZA201803095B/en unknown
-
2019
- 2019-05-17 US US16/415,550 patent/US11738044B2/en active Active
-
2023
- 2023-07-07 US US18/348,799 patent/US12582673B2/en active Active
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