KR102667566B1 - 연장된 용도의 지르코늄 실리케이트 조성물 및 이의 사용 방법 - Google Patents

연장된 용도의 지르코늄 실리케이트 조성물 및 이의 사용 방법 Download PDF

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KR102667566B1
KR102667566B1 KR1020187013243A KR20187013243A KR102667566B1 KR 102667566 B1 KR102667566 B1 KR 102667566B1 KR 1020187013243 A KR1020187013243 A KR 1020187013243A KR 20187013243 A KR20187013243 A KR 20187013243A KR 102667566 B1 KR102667566 B1 KR 102667566B1
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zirconium silicate
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KR20180067614A (ko
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도널드 제프리 카이저
알바로 에프. 길렘
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제트에스 파마, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/02—Processes using inorganic exchangers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/14—Base exchange silicates, e.g. zeolites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C01B39/06—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis
    • C01B39/08—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis the aluminium atoms being wholly replaced
    • C01B39/085—Group IVB- metallosilicates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020187013243A 2015-10-14 2016-10-10 연장된 용도의 지르코늄 실리케이트 조성물 및 이의 사용 방법 Active KR102667566B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/883,428 US9592253B1 (en) 2015-10-14 2015-10-14 Extended use zirconium silicate compositions and methods of use thereof
US14/883,428 2015-10-14
PCT/US2016/056286 WO2017066128A1 (en) 2015-10-14 2016-10-10 Extended use zirconium silicate compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
KR20180067614A KR20180067614A (ko) 2018-06-20
KR102667566B1 true KR102667566B1 (ko) 2024-05-22

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Country Status (19)

Country Link
US (4) US9592253B1 (enExample)
EP (1) EP3362456A4 (enExample)
JP (1) JP6546700B2 (enExample)
KR (1) KR102667566B1 (enExample)
CN (2) CN108137620B (enExample)
AR (1) AR106369A1 (enExample)
AU (1) AU2016338753C1 (enExample)
CA (1) CA3000950C (enExample)
CL (1) CL2018000916A1 (enExample)
CR (1) CR20180276A (enExample)
EA (2) EA035890B1 (enExample)
HK (1) HK1254808A1 (enExample)
IL (1) IL258478B (enExample)
MX (1) MX2018004440A (enExample)
MY (1) MY187088A (enExample)
PH (1) PH12018500786B1 (enExample)
TW (1) TWI742004B (enExample)
WO (1) WO2017066128A1 (enExample)
ZA (1) ZA201803095B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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SMT201900037T1 (it) 2011-02-11 2019-02-28 Zs Pharma Inc Uso di un silicato di zirconio per il trattamento di iperkaliemia
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
WO2019092179A1 (en) * 2017-11-10 2019-05-16 Sandoz Ag Pharmaceutical compositions comprising zs-9
CN113557024A (zh) 2019-03-13 2021-10-26 阿斯利康(瑞典)有限公司 用于血液透析患者中使用的钾结合剂
CN117342570A (zh) * 2023-09-04 2024-01-05 杭州国瑞生物科技有限公司 一种环硅酸锆钠的a晶型及其制备方法
WO2024061387A2 (zh) * 2023-12-19 2024-03-28 杭州国瑞生物科技有限公司 一种环硅酸锆钠的b晶型及其制备方法与应用

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AU2016338753B2 (en) 2019-04-18
CL2018000916A1 (es) 2018-08-17
CA3000950A1 (en) 2017-04-20
CR20180276A (es) 2018-09-19
US9592253B1 (en) 2017-03-14
KR20180067614A (ko) 2018-06-20
AU2016338753A1 (en) 2018-04-12
CN113143958A (zh) 2021-07-23
US20170151279A1 (en) 2017-06-01
HK1254808A1 (zh) 2019-07-26
AR106369A1 (es) 2018-01-10
JP6546700B2 (ja) 2019-07-17
MY187088A (en) 2021-08-30
EA202091273A1 (ru) 2021-02-03
CN108137620B (zh) 2021-05-18
JP2018530596A (ja) 2018-10-18
PH12018500786B1 (en) 2022-09-07
AU2016338753C1 (en) 2019-08-08
IL258478B (en) 2020-09-30
CN108137620A (zh) 2018-06-08
BR112018007189A2 (pt) 2018-10-16
EA201890875A1 (ru) 2018-11-30
TWI742004B (zh) 2021-10-11
PH12018500786A1 (en) 2018-10-29
WO2017066128A1 (en) 2017-04-20
CA3000950C (en) 2023-10-31
US20190365800A1 (en) 2019-12-05
TW201717972A (zh) 2017-06-01
EP3362456A4 (en) 2019-05-15
US11738044B2 (en) 2023-08-29
IL258478A (en) 2018-05-31
NZ740931A (en) 2024-12-20
MX2018004440A (es) 2018-07-06
US20240009229A1 (en) 2024-01-11
ZA201803095B (en) 2019-11-27
US10300087B2 (en) 2019-05-28
EP3362456A1 (en) 2018-08-22
EA035890B1 (ru) 2020-08-27

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