CA3000950C - Extended use zirconium silicate compositions and methods of use thereof - Google Patents

Extended use zirconium silicate compositions and methods of use thereof Download PDF

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Publication number
CA3000950C
CA3000950C CA3000950A CA3000950A CA3000950C CA 3000950 C CA3000950 C CA 3000950C CA 3000950 A CA3000950 A CA 3000950A CA 3000950 A CA3000950 A CA 3000950A CA 3000950 C CA3000950 C CA 3000950C
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CA
Canada
Prior art keywords
zirconium silicate
ppm
zirconium
ion
silicate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3000950A
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English (en)
French (fr)
Other versions
CA3000950A1 (en
Inventor
Donald Jeffrey Keyser
Alvaro F. Guillem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZS Pharma Inc
Original Assignee
ZS Pharma Inc
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58227650&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3000950(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ZS Pharma Inc filed Critical ZS Pharma Inc
Publication of CA3000950A1 publication Critical patent/CA3000950A1/en
Application granted granted Critical
Publication of CA3000950C publication Critical patent/CA3000950C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/02—Processes using inorganic exchangers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/14—Base exchange silicates, e.g. zeolites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C01B39/06—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis
    • C01B39/08—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis the aluminium atoms being wholly replaced
    • C01B39/085—Group IVB- metallosilicates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA3000950A 2015-10-14 2016-10-10 Extended use zirconium silicate compositions and methods of use thereof Active CA3000950C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/883,428 2015-10-14
US14/883,428 US9592253B1 (en) 2015-10-14 2015-10-14 Extended use zirconium silicate compositions and methods of use thereof
PCT/US2016/056286 WO2017066128A1 (en) 2015-10-14 2016-10-10 Extended use zirconium silicate compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
CA3000950A1 CA3000950A1 (en) 2017-04-20
CA3000950C true CA3000950C (en) 2023-10-31

Family

ID=58227650

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3000950A Active CA3000950C (en) 2015-10-14 2016-10-10 Extended use zirconium silicate compositions and methods of use thereof

Country Status (19)

Country Link
US (4) US9592253B1 (enExample)
EP (1) EP3362456A4 (enExample)
JP (1) JP6546700B2 (enExample)
KR (1) KR102667566B1 (enExample)
CN (2) CN113143958A (enExample)
AR (1) AR106369A1 (enExample)
AU (1) AU2016338753C1 (enExample)
CA (1) CA3000950C (enExample)
CL (1) CL2018000916A1 (enExample)
CR (1) CR20180276A (enExample)
EA (2) EA202091273A1 (enExample)
HK (1) HK1254808A1 (enExample)
IL (1) IL258478B (enExample)
MX (1) MX2018004440A (enExample)
MY (1) MY187088A (enExample)
PH (1) PH12018500786B1 (enExample)
TW (1) TWI742004B (enExample)
WO (1) WO2017066128A1 (enExample)
ZA (1) ZA201803095B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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FI2673237T4 (fi) 2011-02-11 2025-12-12 Zs Pharma Inc Zirkoniumsilikaatin käyttö hyperkalemian hoitamiseen
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
WO2019092179A1 (en) * 2017-11-10 2019-05-16 Sandoz Ag Pharmaceutical compositions comprising zs-9
JP2022524454A (ja) 2019-03-13 2022-05-02 アストラゼネカ・アクチエボラーグ 血液透析患者に使用するカリウム結合剤
CN117342570B (zh) * 2023-09-04 2026-02-10 杭州国瑞生物科技有限公司 一种环硅酸锆钠的a晶型及其制备方法
CN117735564B (zh) * 2023-12-19 2025-12-19 杭州国瑞生物科技有限公司 一种环硅酸锆钠的b晶型及其制备方法与应用
CN120172420B (zh) * 2025-03-21 2025-12-23 时森海(杭州)医药科技有限公司 控制粒径分布的环硅酸锆钠及其制备方法
CN120984211A (zh) * 2025-06-13 2025-11-21 时森海(杭州)医药科技有限公司 生产环硅酸锆钠的反应器和方法

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Also Published As

Publication number Publication date
KR102667566B1 (ko) 2024-05-22
EA202091273A1 (ru) 2021-02-03
EP3362456A4 (en) 2019-05-15
CN108137620B (zh) 2021-05-18
EA035890B1 (ru) 2020-08-27
AR106369A1 (es) 2018-01-10
EA201890875A1 (ru) 2018-11-30
EP3362456A1 (en) 2018-08-22
AU2016338753A1 (en) 2018-04-12
KR20180067614A (ko) 2018-06-20
ZA201803095B (en) 2019-11-27
AU2016338753C1 (en) 2019-08-08
PH12018500786B1 (en) 2022-09-07
WO2017066128A1 (en) 2017-04-20
US9592253B1 (en) 2017-03-14
HK1254808A1 (zh) 2019-07-26
CA3000950A1 (en) 2017-04-20
US20240009229A1 (en) 2024-01-11
US10300087B2 (en) 2019-05-28
CL2018000916A1 (es) 2018-08-17
MX2018004440A (es) 2018-07-06
TW201717972A (zh) 2017-06-01
PH12018500786A1 (en) 2018-10-29
TWI742004B (zh) 2021-10-11
IL258478B (en) 2020-09-30
US12582673B2 (en) 2026-03-24
JP2018530596A (ja) 2018-10-18
AU2016338753B2 (en) 2019-04-18
US11738044B2 (en) 2023-08-29
US20170151279A1 (en) 2017-06-01
BR112018007189A2 (en) 2018-10-16
CN113143958A (zh) 2021-07-23
MY187088A (en) 2021-08-30
JP6546700B2 (ja) 2019-07-17
CN108137620A (zh) 2018-06-08
NZ740931A (en) 2024-12-20
US20190365800A1 (en) 2019-12-05
CR20180276A (es) 2018-09-19
IL258478A (en) 2018-05-31

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