MX2018004440A - Composiciones de silicato de zirconio de uso prolongado y metodos de uso de las mismas. - Google Patents

Composiciones de silicato de zirconio de uso prolongado y metodos de uso de las mismas.

Info

Publication number
MX2018004440A
MX2018004440A MX2018004440A MX2018004440A MX2018004440A MX 2018004440 A MX2018004440 A MX 2018004440A MX 2018004440 A MX2018004440 A MX 2018004440A MX 2018004440 A MX2018004440 A MX 2018004440A MX 2018004440 A MX2018004440 A MX 2018004440A
Authority
MX
Mexico
Prior art keywords
zirconium silicate
methods
silicate compositions
extended
lead content
Prior art date
Application number
MX2018004440A
Other languages
English (en)
Inventor
Jeffrey Keyser Donald
F Guillem Alvaro
Original Assignee
Zs Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58227650&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2018004440(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zs Pharma Inc filed Critical Zs Pharma Inc
Publication of MX2018004440A publication Critical patent/MX2018004440A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/02—Processes using inorganic exchangers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/14—Base exchange silicates, e.g. zeolites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C01B39/06—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis
    • C01B39/08—Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements, i.e. by direct or secondary synthesis the aluminium atoms being wholly replaced
    • C01B39/085—Group IVB- metallosilicates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Geology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a composiciones de silicato de zirconio que tienen un contenido de plomo que está por debajo de 0.6 ppm y a métodos de fabricación de silicato de zirconio a volúmenes de reactor superiores a 200 1 con un contenido de plomo de por debajo de 1.1 ppm. El contenido de plomo del silicato de zirconio de la presente invención se encuentra dentro de los niveles que se consideran aceptables para su uso prolongado, dados los requisitos de dosis para el silicato de zirconio.
MX2018004440A 2015-10-14 2016-10-10 Composiciones de silicato de zirconio de uso prolongado y metodos de uso de las mismas. MX2018004440A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/883,428 US9592253B1 (en) 2015-10-14 2015-10-14 Extended use zirconium silicate compositions and methods of use thereof
PCT/US2016/056286 WO2017066128A1 (en) 2015-10-14 2016-10-10 Extended use zirconium silicate compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2018004440A true MX2018004440A (es) 2018-07-06

Family

ID=58227650

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018004440A MX2018004440A (es) 2015-10-14 2016-10-10 Composiciones de silicato de zirconio de uso prolongado y metodos de uso de las mismas.

Country Status (19)

Country Link
US (4) US9592253B1 (es)
EP (1) EP3362456A4 (es)
JP (1) JP6546700B2 (es)
KR (1) KR102667566B1 (es)
CN (2) CN113143958A (es)
AR (1) AR106369A1 (es)
AU (1) AU2016338753C1 (es)
CA (1) CA3000950C (es)
CL (1) CL2018000916A1 (es)
CR (1) CR20180276A (es)
EA (2) EA202091273A1 (es)
HK (1) HK1254808A1 (es)
IL (1) IL258478B (es)
MX (1) MX2018004440A (es)
MY (1) MY187088A (es)
PH (1) PH12018500786A1 (es)
TW (1) TWI742004B (es)
WO (1) WO2017066128A1 (es)
ZA (1) ZA201803095B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2673237T3 (pl) 2011-02-11 2019-04-30 Zs Pharma Inc Zastosowanie krzemianu cyrkonu do leczenia hiperkaliemii
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
WO2019092179A1 (en) * 2017-11-10 2019-05-16 Sandoz Ag Pharmaceutical compositions comprising zs-9
JP2022524454A (ja) 2019-03-13 2022-05-02 アストラゼネカ・アクチエボラーグ 血液透析患者に使用するカリウム結合剤
CN117342570A (zh) * 2023-09-04 2024-01-05 杭州国瑞生物科技有限公司 一种环硅酸锆钠的a晶型及其制备方法

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE21224E (en) 1939-10-03 Coherent zirconium silicates
US3947279A (en) 1971-12-23 1976-03-30 Owens-Illinois, Inc. Thermally crystallizable glasses possessing precision controlled crystallization and flow properties and process of producing same
US4581141A (en) 1978-02-27 1986-04-08 Purdue Research Foundation Dialysis material and method for removing uremic substances
FR2444005A1 (fr) 1978-12-15 1980-07-11 Ugine Kuhlmann Procede industriel de fabrication en semi-continu de zeolithe a
US4943545A (en) 1987-06-08 1990-07-24 Mobil Oil Corporation Activation of zeolites
US5015453A (en) 1989-04-28 1991-05-14 W. R. Grace & Co.-Conn. Crystalline group IVA metal-containing molecular sieve compositions
US5338527A (en) 1992-08-20 1994-08-16 Uop Zirconium silicate composition, method of preparation and uses thereof
KR0169542B1 (ko) 1992-10-28 1999-01-15 알. 브이. 타테 실리카
US5518707A (en) 1994-10-24 1996-05-21 Uop Metallo germanates
IT1283284B1 (it) 1996-03-21 1998-04-16 Eniricerche Spa Zeolite ers-10 e procedimento per la sua preparazione
FR2750893B1 (fr) 1996-07-12 1998-10-30 Elf Aquitaine Procede de synthese de zeolithe avec agitation homogene du milieu, dispositif et application
US5891417A (en) 1997-04-08 1999-04-06 Uop Llc Zirconium silicate and zirconium germanate molecular sieves and process using the same
US5888472A (en) 1997-04-08 1999-03-30 Uop Llc Zirconium silicate molecular sieves and process using the same
CA2268888A1 (en) 1997-05-12 1998-11-19 Itsuki Uehara Separator for battery and alkali secondary battery using the same
US6007790A (en) 1998-08-13 1999-12-28 Uop Llc Family of microporous indium silicate compositions
US6099737A (en) 1999-03-29 2000-08-08 Uop Llc Process for removing toxins from blood using zirconium metallate or titanium metallate compositions
US6332985B1 (en) 1999-03-29 2001-12-25 Uop Llc Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions
US7041274B2 (en) 1999-10-22 2006-05-09 Intevep, S.A. Aluminosilicate compositions, preparation and use
US20020061521A1 (en) 2000-01-31 2002-05-23 Rosen Craig A. Nucleic acids, proteins, and antibodies
US6379641B1 (en) 2000-05-01 2002-04-30 Uop Llc Microporous rare earth silicates and method of producing same
US6596254B1 (en) 2000-06-12 2003-07-22 Sandia Corporation Niobate-based octahedral molecular sieves
AU2002242103A1 (en) 2001-02-06 2002-08-19 Ash Medical Systems, Inc. Monovalent-selective cation exchangers as oral sorbent therapy
US6579460B1 (en) 2001-03-13 2003-06-17 Uop Llc Process and composition for removing toxins from bodily fluids
US6814871B1 (en) 2001-07-13 2004-11-09 Uop Llc Process for removing pollutants from aqueous streams
US6689335B1 (en) 2002-12-19 2004-02-10 Eastman Kodak Company Silver ion sequester and release agent
US8597778B2 (en) 2003-12-15 2013-12-03 Asahi Kasei Chemicals Corporation Porous formed article and method for production thereof
KR101228233B1 (ko) 2004-03-30 2013-01-31 리립사, 인크. 이온 결합 중합체 및 이의 용도
MX2007007881A (es) 2004-12-28 2007-09-12 Renal Solutions Inc Metodo para sintetizar particulas de fosfato de zirconio.
EP1900691B1 (en) 2005-06-14 2020-01-08 Asahi Kasei Kabushiki Kaisha Apparatus for water treatment and method of treating water
KR20080057319A (ko) 2005-09-30 2008-06-24 일립사, 인코포레이티드 가교 쉘을 갖는 코어-쉘 복합체의 제조 방법, 및 이로부터수득되는 코어-쉘 복합체
WO2007041569A1 (en) 2005-09-30 2007-04-12 Ilypsa, Inc. Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
US7297318B2 (en) * 2005-11-17 2007-11-20 J.M. Huber Corporation Method of removing heavy metals from silicate sources during silicate manufacturing
US7201885B1 (en) * 2005-11-17 2007-04-10 J.M. Huber Corporation Method of removing heavy metals from silicate sources during silicate manufacturing
US8367112B2 (en) 2006-02-28 2013-02-05 Alkermes Pharma Ireland Limited Nanoparticulate carverdilol formulations
WO2007127390A2 (en) 2006-04-28 2007-11-08 Biolife, L.L.C. Materials and methods for wound treatment
US8093350B2 (en) 2007-01-03 2012-01-10 Insilicotech Co., Ltd Coordination polymer crystal with porous metal-organic frameworks and preparation method thereof
ES2304890B1 (es) 2007-04-03 2009-10-30 Universidad De Zaragoza Procedimiento de obtencion de esferas de titanosilicato.
DE202009018723U1 (de) 2008-02-26 2012-11-20 Corning Inc. Läutermittel für Silikatgläser
KR102150184B1 (ko) 2008-08-22 2020-08-31 리립사, 인크. 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도
US20100104527A1 (en) 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US8865121B2 (en) 2009-06-18 2014-10-21 Basf Se Organotemplate-free synthetic process for the production of a zeolitic material
GB0913525D0 (en) * 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
US20120070468A1 (en) 2010-09-16 2012-03-22 Uop Llc Removal of toxins from gastrointestinal fluids
PL2673237T3 (pl) * 2011-02-11 2019-04-30 Zs Pharma Inc Zastosowanie krzemianu cyrkonu do leczenia hiperkaliemii
US8710271B2 (en) 2011-04-08 2014-04-29 Basf Se Process for the production of an acylation catalyst
US9527751B2 (en) 2011-11-11 2016-12-27 Basf Se Organotemplate-free synthetic process for the production of a zeolitic material of the CHA-type structure
EP2812281B1 (en) 2012-02-06 2020-07-29 Basf Se Iron- and copper-containing zeolite beta from organotemplate-free synthesis and use thereof in the selective catalytic reduction of nox
US9475041B2 (en) 2012-04-24 2016-10-25 Basf Se Zeolitic materials and methods for their preparation using alkenyltrialkylammonium compounds
KR20150036555A (ko) * 2012-07-11 2015-04-07 제트에스 파마, 인코포레이티드 고칼슘혈증 환자에서 고칼륨혈증의 치료를 위한 미세다공성 지르코늄 실리케이트 및 고칼륨혈증의 치료를 위한 개선된 칼슘-함유 조성물
EP2882444A4 (en) * 2012-10-22 2016-03-02 Zs Pharma Inc MICROPOROUS ZIRCONESILICATE FOR THE TREATMENT OF HYPERKALIEMIA
HUE061862T2 (hu) * 2013-04-05 2023-08-28 Zs Pharma Inc Mikropórusos cirkónium-szilikát és vízhajtók a káliumszint csökkentésére és krónikus vese- és/vagy krónikus szívbetegség kezelésére
EP4378577A2 (en) * 2013-11-08 2024-06-05 ZS Pharma, Inc Microporous zirconium silicate for the treatment of hyperkalemia
US20150313938A1 (en) * 2013-12-10 2015-11-05 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia without co-administration of lithium
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof

Also Published As

Publication number Publication date
US20190365800A1 (en) 2019-12-05
ZA201803095B (en) 2019-11-27
CN113143958A (zh) 2021-07-23
JP6546700B2 (ja) 2019-07-17
CL2018000916A1 (es) 2018-08-17
HK1254808A1 (zh) 2019-07-26
CR20180276A (es) 2018-09-19
MY187088A (en) 2021-08-30
US10300087B2 (en) 2019-05-28
US9592253B1 (en) 2017-03-14
AR106369A1 (es) 2018-01-10
PH12018500786A1 (en) 2018-10-29
IL258478A (en) 2018-05-31
CN108137620B (zh) 2021-05-18
KR102667566B1 (ko) 2024-05-22
EP3362456A4 (en) 2019-05-15
AU2016338753A1 (en) 2018-04-12
US20240009229A1 (en) 2024-01-11
TW201717972A (zh) 2017-06-01
JP2018530596A (ja) 2018-10-18
CA3000950C (en) 2023-10-31
EA202091273A1 (ru) 2021-02-03
US20170151279A1 (en) 2017-06-01
EA035890B1 (ru) 2020-08-27
US11738044B2 (en) 2023-08-29
IL258478B (en) 2020-09-30
CA3000950A1 (en) 2017-04-20
AU2016338753B2 (en) 2019-04-18
TWI742004B (zh) 2021-10-11
CN108137620A (zh) 2018-06-08
EA201890875A1 (ru) 2018-11-30
WO2017066128A1 (en) 2017-04-20
KR20180067614A (ko) 2018-06-20
EP3362456A1 (en) 2018-08-22
BR112018007189A2 (pt) 2018-10-16
AU2016338753C1 (en) 2019-08-08

Similar Documents

Publication Publication Date Title
PH12018500786A1 (en) Extended use zirconium compositions and methods of use thereof
MX2022009148A (es) Composiciones y metodos para el tratamiento de hemoglobinopatias.
PL3468972T3 (pl) Związki i kompozycje do hamowania aktywności shp2
PH12016501151A1 (en) Nrf2 regulators
MX2017013556A (es) Compuestos novedosos.
PH12016501578A1 (en) Pharmaceutical compounds
GEP20186921B (en) Pyrazolopyridines and pyrazolopyrimidines
PH12017500745A1 (en) Bromodomain inhibitors
TW201614041A (en) Compositions for electronic devices
PL3082831T3 (pl) Kompozycje oparte na metylocyklodekstrynach do leczenia i/lub zapobiegania chorobom poprzez podwyższenie poziomu cholesterolu HDL
MX2015008766A (es) Compuestos cbd fluorados, composiciones y usos de los mismos.
NZ702930A (en) Racecadotril liquid compositions
MX370412B (es) Compuesto antimicotico.
IN2013MU03641A (es)
MX2017012596A (es) Una composicion farmaceutica y el uso de la misma.
MX2015000179A (es) Composiciones y formas de dosificacion de itraconazol y metodos de uso de las mismas.
IN2013CH06132A (es)
MA40027A (fr) Composition pharmaceutique comprenant un bêta-2 agoniste et un agent anticholinergique
MX2017004716A (es) Composiciones a base de 1,1,1,3,3-pentacloropropano.
PH12017501897A1 (en) 2-thiopyrimidinones
MX2020005231A (es) Metodos de uso y composiciones que contienen dulaglutida.
MX368216B (es) Estabilidad del peróxido.
MX366144B (es) Composiciones para el cuidado oral que comprenden compuestos de zinc y compuestos de peroxido.
MX2016013108A (es) Nueva composicion para el tratamiento de la tricomoniasis.
MX2018008220A (es) Composiciones cosmeticas que comprenden combinacion sinergica de particulas absorbentes y adsorbentes de sudor y usos de las mismas.

Legal Events

Date Code Title Description
GD Licence granted
FG Grant or registration