JP2018530591A5 - - Google Patents

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JP2018530591A5
JP2018530591A5 JP2018519425A JP2018519425A JP2018530591A5 JP 2018530591 A5 JP2018530591 A5 JP 2018530591A5 JP 2018519425 A JP2018519425 A JP 2018519425A JP 2018519425 A JP2018519425 A JP 2018519425A JP 2018530591 A5 JP2018530591 A5 JP 2018530591A5
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JP
Japan
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carbonyl
dimethoxyphenyl
pyridine
diol
butyl
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JP2018519425A
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English (en)
Japanese (ja)
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JP2018530591A (ja
JP6837482B2 (ja
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Priority claimed from PCT/US2016/056769 external-priority patent/WO2017066402A1/en
Publication of JP2018530591A publication Critical patent/JP2018530591A/ja
Publication of JP2018530591A5 publication Critical patent/JP2018530591A5/ja
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JP2018519425A 2015-10-14 2016-10-13 Apjアゴニストとしての2,4−ジヒドロキシ−ニコチンアミド Active JP6837482B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562241367P 2015-10-14 2015-10-14
US62/241,367 2015-10-14
US201562270659P 2015-12-22 2015-12-22
US62/270,659 2015-12-22
PCT/US2016/056769 WO2017066402A1 (en) 2015-10-14 2016-10-13 2,4-dihydroxy-nicotinamides as apj agonists

Publications (3)

Publication Number Publication Date
JP2018530591A JP2018530591A (ja) 2018-10-18
JP2018530591A5 true JP2018530591A5 (enExample) 2019-11-21
JP6837482B2 JP6837482B2 (ja) 2021-03-03

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JP2018519425A Active JP6837482B2 (ja) 2015-10-14 2016-10-13 Apjアゴニストとしての2,4−ジヒドロキシ−ニコチンアミド

Country Status (20)

Country Link
US (1) US10392347B2 (enExample)
EP (1) EP3362442B1 (enExample)
JP (1) JP6837482B2 (enExample)
KR (1) KR102707502B1 (enExample)
CN (1) CN108368087B (enExample)
AU (1) AU2016340264B2 (enExample)
BR (1) BR112018007395A2 (enExample)
CA (1) CA3001974A1 (enExample)
CL (1) CL2018000953A1 (enExample)
CO (1) CO2018004968A2 (enExample)
EA (1) EA034857B1 (enExample)
ES (1) ES2774945T3 (enExample)
IL (1) IL258577B (enExample)
MX (1) MX376824B (enExample)
PE (1) PE20181197A1 (enExample)
SG (1) SG10201908839QA (enExample)
TW (1) TW201720796A (enExample)
UY (1) UY36949A (enExample)
WO (1) WO2017066402A1 (enExample)
ZA (1) ZA201802451B (enExample)

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WO2018097944A1 (en) 2016-11-16 2018-05-31 Amgen Inc. Triazole furan compounds as agonists of the apj receptor
MA50509A (fr) 2017-11-03 2021-06-02 Amgen Inc Agonistes de triazole fusionnés du récepteur apj
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RS59220B1 (sr) 2015-06-03 2019-10-31 Bristol Myers Squibb Co 4-hidroksi-3-(heteroaril)piridin-2-on apj agonisti za primenu u lečenju kardiovaskularnih poremećaja
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JP6948322B2 (ja) 2015-12-16 2021-10-13 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Apj受容体のapjアゴニストとしてのヘテロアリールヒドロキシピリミジノン
JP6716711B2 (ja) 2016-03-24 2020-07-01 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Apjアゴニストとしての6−ヒドロキシ−4−オキソ−1,4−ジヒドロピリミジン−5−カルボキシアミド
EP3468952B1 (en) 2016-06-14 2020-11-25 Bristol-Myers Squibb Company 4-hydroxy-3-sulfonylpyridin-2(1h)-ones as apj receptor agonists
KR102384668B1 (ko) 2016-06-14 2022-04-07 브리스톨-마이어스 스큅 컴퍼니 Apj 효능제로서의 6-히드록시-5-(페닐/헤테로아릴술포닐)피리미딘-4(1h)-온
CN110072850B (zh) 2016-10-14 2023-07-21 百时美施贵宝公司 3-磺酰基-5-氨基吡啶-2,4-二醇apj激动剂

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