JP2018529389A - 神経前駆細胞集団およびそれらの使用 - Google Patents

神経前駆細胞集団およびそれらの使用 Download PDF

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Publication number
JP2018529389A
JP2018529389A JP2018538528A JP2018538528A JP2018529389A JP 2018529389 A JP2018529389 A JP 2018529389A JP 2018538528 A JP2018538528 A JP 2018538528A JP 2018538528 A JP2018538528 A JP 2018538528A JP 2018529389 A JP2018529389 A JP 2018529389A
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Prior art keywords
cells
neural progenitor
cell
enriched
cell population
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JP2018538528A
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Japanese (ja)
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JP2018529389A5 (https=
Inventor
ニコラス、コリー
フエンテアルバ、ルイス
カー トン、チュク
カー トン、チュク
ベルシュテイン、マリーナ
クリクス、ソーニャ
チェンバーズ、スチュアート
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Neurona Therapeutics Inc
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Neurona Therapeutics Inc
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Publication of JP2018529389A publication Critical patent/JP2018529389A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2018538528A 2015-10-08 2016-10-10 神経前駆細胞集団およびそれらの使用 Pending JP2018529389A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562239042P 2015-10-08 2015-10-08
US62/239,042 2015-10-08
PCT/US2016/056316 WO2017062971A1 (en) 2015-10-08 2016-10-10 Neural precursor cell populations and uses thereof

Related Child Applications (1)

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JP2020150010A Division JP7138959B2 (ja) 2015-10-08 2020-09-07 神経前駆細胞集団を作出する方法

Publications (2)

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JP2018529389A true JP2018529389A (ja) 2018-10-11
JP2018529389A5 JP2018529389A5 (https=) 2019-04-25

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JP2018538528A Pending JP2018529389A (ja) 2015-10-08 2016-10-10 神経前駆細胞集団およびそれらの使用
JP2020150010A Active JP7138959B2 (ja) 2015-10-08 2020-09-07 神経前駆細胞集団を作出する方法
JP2022137961A Active JP7598655B2 (ja) 2015-10-08 2022-08-31 神経前駆細胞集団を含むインビトロ組成物およびその使用
JP2024204447A Pending JP2025022948A (ja) 2015-10-08 2024-11-25 神経前駆細胞集団を含むインビトロ組成物およびその使用

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JP2020150010A Active JP7138959B2 (ja) 2015-10-08 2020-09-07 神経前駆細胞集団を作出する方法
JP2022137961A Active JP7598655B2 (ja) 2015-10-08 2022-08-31 神経前駆細胞集団を含むインビトロ組成物およびその使用
JP2024204447A Pending JP2025022948A (ja) 2015-10-08 2024-11-25 神経前駆細胞集団を含むインビトロ組成物およびその使用

Country Status (8)

Country Link
US (1) US20180369287A1 (https=)
EP (1) EP3359647A1 (https=)
JP (4) JP2018529389A (https=)
CN (1) CN108291207A (https=)
AU (3) AU2016335563B2 (https=)
CA (1) CA3001316A1 (https=)
HK (1) HK1258172A1 (https=)
WO (1) WO2017062971A1 (https=)

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WO2015069736A1 (en) 2013-11-08 2015-05-14 The Mclean Hospital Corporation METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS
US12343359B2 (en) 2019-05-23 2025-07-01 Dignity Health Inhibitory interneuron treatment methods, uses and compositions for diabetes
WO2023004345A1 (en) * 2021-07-21 2023-01-26 University Of Washington Compositions and methods for enhancing cardiomyocyte transplant engraftment
KR102684884B1 (ko) * 2021-08-05 2024-07-15 성균관대학교산학협력단 신경줄기세포의 줄기세포능 증진을 위한 gng2의 용도
CN113826564A (zh) * 2021-08-31 2021-12-24 南通大学 一种检测小鼠运动能力的方法
CN114736957B (zh) * 2022-04-15 2024-03-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
CN118064356A (zh) * 2022-11-22 2024-05-24 浙江霍德生物工程有限公司 前脑神经前体细胞在治疗与前脑神经细胞的死亡和/或功能不全相关的疾病中的应用
WO2025075929A1 (en) * 2023-10-02 2025-04-10 Neurona Therapeutics Inc. Methods of treating seizure activity
CN117092354B (zh) * 2023-10-18 2023-12-29 亿航(苏州)生物医药有限公司 一种用于识别脑源性细胞的细胞外囊泡的蛋白标志物

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Also Published As

Publication number Publication date
JP2025022948A (ja) 2025-02-14
AU2025283558A1 (en) 2026-01-15
HK1258172A1 (zh) 2019-11-08
US20180369287A1 (en) 2018-12-27
EP3359647A1 (en) 2018-08-15
JP2022169768A (ja) 2022-11-09
JP7138959B2 (ja) 2022-09-20
CA3001316A1 (en) 2017-04-13
JP7598655B2 (ja) 2024-12-12
AU2023200389A1 (en) 2023-02-23
AU2016335563A1 (en) 2018-05-24
AU2023200389B2 (en) 2025-09-25
AU2016335563B2 (en) 2022-10-27
CN108291207A (zh) 2018-07-17
WO2017062971A1 (en) 2017-04-13
JP2020202865A (ja) 2020-12-24

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