CA3001316A1 - Neural precursor cell populations and uses thereof - Google Patents
Neural precursor cell populations and uses thereof Download PDFInfo
- Publication number
- CA3001316A1 CA3001316A1 CA3001316A CA3001316A CA3001316A1 CA 3001316 A1 CA3001316 A1 CA 3001316A1 CA 3001316 A CA3001316 A CA 3001316A CA 3001316 A CA3001316 A CA 3001316A CA 3001316 A1 CA3001316 A1 CA 3001316A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- cell
- neural precursor
- population
- enriched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562239042P | 2015-10-08 | 2015-10-08 | |
| US62/239,042 | 2015-10-08 | ||
| PCT/US2016/056316 WO2017062971A1 (en) | 2015-10-08 | 2016-10-10 | Neural precursor cell populations and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3001316A1 true CA3001316A1 (en) | 2017-04-13 |
Family
ID=57200130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3001316A Pending CA3001316A1 (en) | 2015-10-08 | 2016-10-10 | Neural precursor cell populations and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180369287A1 (https=) |
| EP (1) | EP3359647A1 (https=) |
| JP (4) | JP2018529389A (https=) |
| CN (1) | CN108291207A (https=) |
| AU (3) | AU2016335563B2 (https=) |
| CA (1) | CA3001316A1 (https=) |
| HK (1) | HK1258172A1 (https=) |
| WO (1) | WO2017062971A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015069736A1 (en) | 2013-11-08 | 2015-05-14 | The Mclean Hospital Corporation | METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS |
| JP2022043373A (ja) * | 2018-12-28 | 2022-03-16 | 国立大学法人京都大学 | 大脳皮質細胞からのl1cam陽性細胞の取得およびその細胞製剤としての使用 |
| US12343359B2 (en) | 2019-05-23 | 2025-07-01 | Dignity Health | Inhibitory interneuron treatment methods, uses and compositions for diabetes |
| WO2023004345A1 (en) * | 2021-07-21 | 2023-01-26 | University Of Washington | Compositions and methods for enhancing cardiomyocyte transplant engraftment |
| KR102684884B1 (ko) * | 2021-08-05 | 2024-07-15 | 성균관대학교산학협력단 | 신경줄기세포의 줄기세포능 증진을 위한 gng2의 용도 |
| CN113826564A (zh) * | 2021-08-31 | 2021-12-24 | 南通大学 | 一种检测小鼠运动能力的方法 |
| CN114736957B (zh) * | 2022-04-15 | 2024-03-12 | 中国人民解放军空军军医大学 | 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用 |
| CN118064356A (zh) * | 2022-11-22 | 2024-05-24 | 浙江霍德生物工程有限公司 | 前脑神经前体细胞在治疗与前脑神经细胞的死亡和/或功能不全相关的疾病中的应用 |
| WO2025075929A1 (en) * | 2023-10-02 | 2025-04-10 | Neurona Therapeutics Inc. | Methods of treating seizure activity |
| CN117092354B (zh) * | 2023-10-18 | 2023-12-29 | 亿航(苏州)生物医药有限公司 | 一种用于识别脑源性细胞的细胞外囊泡的蛋白标志物 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| WO2001088104A2 (en) | 2000-05-17 | 2001-11-22 | Geron Corporation | Neural progenitor cell populations |
| EP2298867A3 (en) | 2000-06-20 | 2013-01-16 | ES Cell International Pte Ltd. | Method of controlling differentiation of embryonic stem (ES) cells by culturing ES cells in the presence of bmp-2 pathway antagonists |
| JPWO2004005496A1 (ja) | 2002-07-05 | 2005-11-04 | 麒麟麦酒株式会社 | 臍帯血、骨髄、末梢血等に含まれる新規な未分化幹細胞集団 |
| US20060211111A1 (en) | 2002-12-18 | 2006-09-21 | Maisam Mitalipova | Compositions and methods for neural cell production and stabilization |
| ZA200401646B (en) * | 2003-03-12 | 2004-06-07 | Reliance Life Sciences Pvt Ltd | Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells. |
| US20070020608A1 (en) | 2003-05-08 | 2007-01-25 | Peter Eriksson | Method for the generation of neural progenitor cells |
| US7820439B2 (en) | 2003-09-03 | 2010-10-26 | Reliance Life Sciences Pvt Ltd. | In vitro generation of GABAergic neurons from pluripotent stem cells |
| US7682828B2 (en) | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
| JP2008501320A (ja) | 2004-06-02 | 2008-01-24 | イーエス・セル・インターナショナル・プライヴェート・リミテッド | 細胞保存方法 |
| US20060008451A1 (en) | 2004-07-06 | 2006-01-12 | Michigan State University | In vivo methods for effecting tissue specific differentiation of embryonic stem cells |
| EP1814979B1 (en) * | 2004-11-17 | 2015-04-08 | Neuralstem, Inc. | Transplantation of human neural cells for treatment of neurodegenerative conditions |
| EP1856248A4 (en) | 2005-02-09 | 2010-01-20 | Burnham Inst Medical Research | HOMOGENEOUS NEURALE CURRENT CELLS |
| WO2006091766A2 (en) | 2005-02-24 | 2006-08-31 | Jau-Nan Lee | Human trophoblast stem cells and use thereof |
| US7803364B2 (en) | 2005-11-17 | 2010-09-28 | The Cleveland Clinic Foundation | Multipotent neural stem cells |
| WO2007067280A2 (en) | 2005-12-08 | 2007-06-14 | University Of Louisville Research Foundation, Inc. | Very small embryonic-like (vsel) stem cells and methods of isolating and using the same |
| CA2645186A1 (en) * | 2006-01-20 | 2007-07-26 | The Regents Of The University Of California | Transplantation of neural cells |
| ES2663875T3 (es) | 2006-11-03 | 2018-04-17 | Multiple Sclerosis Research Center Of New York | Células madre mesenquimáticas derivadas de la médula ósea como fuente de progenitores neurales |
| EP2607477B1 (en) | 2007-05-03 | 2020-09-23 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20100287638A1 (en) | 2007-10-01 | 2010-11-11 | The Hospital For Sick Children | Neural tumor stem cells and methods of use thereof |
| US20110165129A1 (en) | 2008-05-06 | 2011-07-07 | Arnold Kriegstein | Ameliorating Nervous Systems Disorders |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| KR20110015739A (ko) | 2009-08-10 | 2011-02-17 | 삼성전자주식회사 | Emi방사 저감을 위한 플라즈마 디스플레이 장치 |
| WO2011079307A2 (en) | 2009-12-23 | 2011-06-30 | The Salk Institute For Biological Studies | Methods and compositions for treating neurological disorders |
| WO2011091048A1 (en) | 2010-01-19 | 2011-07-28 | The Board Of Trustees Of The Leland Stanford Junior University | Direct conversion of cells to cells of other lineages |
| CA2835215C (en) * | 2011-05-18 | 2023-10-10 | The Regents Of The University Of California | Non-immortal human retinal cell compositions, method for preparing them, and their use for treating retinal diseases |
| WO2013076726A1 (en) | 2011-11-21 | 2013-05-30 | Ramot At Tel-Aviv University Ltd. | Stem cell-derived neural cells for cell therapy in neurological disorders |
| KR101429217B1 (ko) | 2012-02-06 | 2014-08-12 | 동국대학교 산학협력단 | 줄기세포를 신경세포로 분화시키는 방법 |
| WO2013139429A1 (en) | 2012-03-21 | 2013-09-26 | Merck Patent Gmbh | Induced neural stem cells |
| WO2013155222A2 (en) | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| JP2014082956A (ja) | 2012-10-19 | 2014-05-12 | Somar Corp | 細胞培養基材、およびそれを用いた細胞培養方法並びに多能性幹細胞の分化誘導方法 |
| CA2899507A1 (en) * | 2013-03-14 | 2014-09-25 | The Regents Of The University Of California | In vitro production of medial ganglionic eminence precursor cells |
| EP3498824A1 (en) | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| CN106164255B (zh) | 2013-09-20 | 2020-02-14 | 隆萨有限公司 | 细胞的核重编程的方法 |
| WO2015069736A1 (en) | 2013-11-08 | 2015-05-14 | The Mclean Hospital Corporation | METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS |
-
2016
- 2016-10-10 US US15/766,792 patent/US20180369287A1/en active Pending
- 2016-10-10 AU AU2016335563A patent/AU2016335563B2/en active Active
- 2016-10-10 WO PCT/US2016/056316 patent/WO2017062971A1/en not_active Ceased
- 2016-10-10 EP EP16785645.9A patent/EP3359647A1/en active Pending
- 2016-10-10 JP JP2018538528A patent/JP2018529389A/ja active Pending
- 2016-10-10 HK HK19100528.0A patent/HK1258172A1/zh unknown
- 2016-10-10 CA CA3001316A patent/CA3001316A1/en active Pending
- 2016-10-10 CN CN201680071312.9A patent/CN108291207A/zh active Pending
-
2020
- 2020-09-07 JP JP2020150010A patent/JP7138959B2/ja active Active
-
2022
- 2022-08-31 JP JP2022137961A patent/JP7598655B2/ja active Active
-
2023
- 2023-01-25 AU AU2023200389A patent/AU2023200389B2/en active Active
-
2024
- 2024-11-25 JP JP2024204447A patent/JP2025022948A/ja active Pending
-
2025
- 2025-12-18 AU AU2025283558A patent/AU2025283558A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025022948A (ja) | 2025-02-14 |
| JP2018529389A (ja) | 2018-10-11 |
| AU2025283558A1 (en) | 2026-01-15 |
| HK1258172A1 (zh) | 2019-11-08 |
| US20180369287A1 (en) | 2018-12-27 |
| EP3359647A1 (en) | 2018-08-15 |
| JP2022169768A (ja) | 2022-11-09 |
| JP7138959B2 (ja) | 2022-09-20 |
| JP7598655B2 (ja) | 2024-12-12 |
| AU2023200389A1 (en) | 2023-02-23 |
| AU2016335563A1 (en) | 2018-05-24 |
| AU2023200389B2 (en) | 2025-09-25 |
| AU2016335563B2 (en) | 2022-10-27 |
| CN108291207A (zh) | 2018-07-17 |
| WO2017062971A1 (en) | 2017-04-13 |
| JP2020202865A (ja) | 2020-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20211008 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 8TH ANNIV.) - STANDARD Year of fee payment: 8 |
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| D15 | Examination report completed |
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| W00 | Other event occurred |
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| D15 | Examination report completed |
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