JP2018528776A5 - - Google Patents
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- JP2018528776A5 JP2018528776A5 JP2018513633A JP2018513633A JP2018528776A5 JP 2018528776 A5 JP2018528776 A5 JP 2018528776A5 JP 2018513633 A JP2018513633 A JP 2018513633A JP 2018513633 A JP2018513633 A JP 2018513633A JP 2018528776 A5 JP2018528776 A5 JP 2018528776A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antibody
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562218990P | 2015-09-15 | 2015-09-15 | |
| US62/218,990 | 2015-09-15 | ||
| PCT/US2016/051847 WO2017048902A1 (en) | 2015-09-15 | 2016-09-15 | T-cell receptor (tcr)-binding antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528776A JP2018528776A (ja) | 2018-10-04 |
| JP2018528776A5 true JP2018528776A5 (cg-RX-API-DMAC10.html) | 2019-10-17 |
| JP7020687B2 JP7020687B2 (ja) | 2022-02-16 |
Family
ID=56990993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513633A Expired - Fee Related JP7020687B2 (ja) | 2015-09-15 | 2016-09-15 | Ｔ細胞受容体（ｔｃｒ）結合抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10633445B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3349791A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7020687B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20180042449A (cg-RX-API-DMAC10.html) |
| CN (1) | CN108430506A (cg-RX-API-DMAC10.html) |
| AU (2) | AU2016323153B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2997673A1 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1258218A1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL258009B2 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2017048902A1 (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA202002966B (cg-RX-API-DMAC10.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2997134B1 (en) | 2013-05-14 | 2020-06-24 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| DK3105335T3 (da) | 2014-02-14 | 2020-01-13 | Univ Texas | Kimære antigenreceptorer og fremgangsmåder til fremstilling heraf |
| CA2964783C (en) | 2014-11-05 | 2024-01-23 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| US10808230B2 (en) | 2015-02-24 | 2020-10-20 | Board Of Regents, The University Of Texas System | Selection methods for genetically-modified T cells |
| JP6775515B2 (ja) | 2015-03-11 | 2020-10-28 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | トランスポザーゼポリペプチド及びその使用 |
| EP3349791A1 (en) | 2015-09-15 | 2018-07-25 | Board of Regents, The University of Texas System | T-cell receptor (tcr)-binding antibodies and uses thereof |
| WO2017075147A1 (en) | 2015-10-27 | 2017-05-04 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor molecules and uses thereof |
| JP2020517259A (ja) * | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| EP3700932A1 (en) * | 2017-10-27 | 2020-09-02 | Kite Pharma, Inc. | T cell receptor antigen binding molecules and methods of use thereof |
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| WO2020010229A1 (en) * | 2018-07-06 | 2020-01-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Car t cell therapy to target t cell specific cancers |
| CN109136282A (zh) * | 2018-09-30 | 2019-01-04 | 北京鼎成肽源生物技术有限公司 | 一种hafft1细胞的构建方法 |
| CN114360644B (zh) * | 2021-12-30 | 2024-12-17 | 山东师范大学 | T细胞受体与抗原表位的结合预测方法及系统 |
| CN117624340B (zh) * | 2024-01-23 | 2024-04-30 | 北京臻知医学科技有限责任公司 | 识别人乙型肝炎病毒（hbv）抗原的t细胞受体（tcr）及其用途 |
| WO2025247325A1 (en) * | 2024-05-30 | 2025-12-04 | Hanx Biopharmaceuticals, (Wuhan) Ltd. | Antibody-drug conjugates targeting trbv12 and uses thereof |
| WO2026019819A1 (en) * | 2024-07-15 | 2026-01-22 | The Research Foundation For The State University Of New York | Development and optimization of an mrna-vectored single-chain iga1 isotype monoclonal antibody to treat or prevent dengue virus infection |
| WO2026026858A1 (en) * | 2024-07-30 | 2026-02-05 | Biomap (Suzhou) Intelligent Technology Limited | Dsg2 antibody and uses thereof |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982002533A1 (en) | 1981-01-14 | 1982-08-05 | Michael G Knickerbocker | Valve assembly with integral plastic spring |
| US4714681A (en) | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| GB2183662B (en) | 1985-04-01 | 1989-01-25 | Celltech Ltd | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| JPS63212525A (ja) | 1987-02-28 | 1988-09-05 | Nissei Plastics Ind Co | 型締装置 |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| WO1989012624A2 (en) | 1988-06-14 | 1989-12-28 | Cetus Corporation | Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom |
| US5601819A (en) | 1988-08-11 | 1997-02-11 | The General Hospital Corporation | Bispecific antibodies for selective immune regulation and for selective immune cell binding |
| US5223426A (en) * | 1988-12-15 | 1993-06-29 | T Cell Sciences, Inc. | Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| IE63847B1 (en) | 1989-05-05 | 1995-06-14 | Res Dev Foundation | A novel antibody delivery system for biological response modifiers |
| EP0739904A1 (en) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispecific reagents for aids therapy |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5314995A (en) | 1990-01-22 | 1994-05-24 | Oncogen | Therapeutic interleukin-2-antibody based fusion proteins |
| DE69127749T2 (de) | 1990-03-20 | 1998-04-16 | The Trustees Of Columbia University In The City Of New York, New York, N.Y. | Chimäre antikörper mit rezeptor-bindenden liganden anstelle ihrer konstanten region |
| DK0553244T4 (da) | 1990-10-05 | 2005-08-01 | Celldex Therapeutics Inc | Målrettet immunostimulering med bispecifikke reagenser |
| AU8727291A (en) | 1990-10-29 | 1992-06-11 | Cetus Oncology Corporation | Bispecific antibodies, method of production, and uses thereof |
| ATE218889T1 (de) | 1990-11-09 | 2002-06-15 | Stephen D Gillies | Cytokine immunokonjugate |
| EP0582595A1 (en) | 1991-04-26 | 1994-02-16 | Surface Active Limited | Novel antibodies, and methods for their use |
| EP1306095A3 (en) | 1992-03-05 | 2003-06-25 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US20020064528A1 (en) | 2000-01-28 | 2002-05-30 | Zhenping Zhu | Antibodies specific to KDR and uses thereof |
| US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
| US6849425B1 (en) | 1999-10-14 | 2005-02-01 | Ixsys, Inc. | Methods of optimizing antibody variable region binding affinity |
| CN1306272C (zh) | 2000-11-17 | 2007-03-21 | 罗切斯特大学 | 筛选编码抗原特异性免疫球蛋白分子或其抗原特异性片段的方法 |
| AU2002327164A1 (en) | 2001-01-29 | 2002-12-09 | Idec Pharmaceuticals Corporation | Engineered tetravalent antibodies and methods of use |
| AU2002368077B2 (en) | 2001-07-12 | 2010-03-04 | Jefferson Foote | Super humanized antibodies |
| US20030020733A1 (en) | 2001-07-24 | 2003-01-30 | Yin Memphis Zhihong | Computer display having selective area magnification |
| WO2003068819A1 (en) * | 2001-12-22 | 2003-08-21 | 4-Antibody Ag | Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins |
| US9169329B2 (en) * | 2010-06-01 | 2015-10-27 | Ludwig Institute For Cancer Research | Antibodies directed to the receptor tyrosine kinase c-Met |
| EP2611832B1 (en) | 2010-09-02 | 2017-11-29 | Vaccinex, Inc. | Anti-cxcl13 antibodies and methods of using the same |
| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| TWI864338B (zh) * | 2012-11-14 | 2024-12-01 | 美商再生元醫藥公司 | 重組細胞表面捕捉蛋白質 |
| US9505849B2 (en) * | 2013-03-15 | 2016-11-29 | Amgen Research (Munich) Gmbh | Antibody constructs for influenza M2 and CD3 |
| EP2997134B1 (en) | 2013-05-14 | 2020-06-24 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| CA2913052A1 (en) | 2013-05-24 | 2014-11-27 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| US9907820B2 (en) | 2013-10-25 | 2018-03-06 | Board Of Regents, The University Of Texas System | Polyclonal gamma delta T cells for immunotherapy |
| DK3105335T3 (da) | 2014-02-14 | 2020-01-13 | Univ Texas | Kimære antigenreceptorer og fremgangsmåder til fremstilling heraf |
| US20170158749A1 (en) | 2014-04-23 | 2017-06-08 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) and methods for making and using the same |
| KR20160145186A (ko) | 2014-04-24 | 2016-12-19 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 입양 세포 요법 생성물을 생성하기 위한 유도 만능 줄기 세포의 응용 |
| CA2964785A1 (en) | 2014-11-05 | 2016-05-12 | Board Of Regents, The University Of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| CA2964783C (en) | 2014-11-05 | 2024-01-23 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| US10808230B2 (en) | 2015-02-24 | 2020-10-20 | Board Of Regents, The University Of Texas System | Selection methods for genetically-modified T cells |
| JP6775515B2 (ja) | 2015-03-11 | 2020-10-28 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | トランスポザーゼポリペプチド及びその使用 |
| EP3349791A1 (en) | 2015-09-15 | 2018-07-25 | Board of Regents, The University of Texas System | T-cell receptor (tcr)-binding antibodies and uses thereof |
| WO2017075147A1 (en) | 2015-10-27 | 2017-05-04 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor molecules and uses thereof |
-
2016
- 2016-09-15 EP EP16770634.0A patent/EP3349791A1/en not_active Withdrawn
- 2016-09-15 HK HK19100576.1A patent/HK1258218A1/zh unknown
- 2016-09-15 IL IL258009A patent/IL258009B2/en unknown
- 2016-09-15 WO PCT/US2016/051847 patent/WO2017048902A1/en not_active Ceased
- 2016-09-15 AU AU2016323153A patent/AU2016323153B2/en not_active Ceased
- 2016-09-15 CA CA2997673A patent/CA2997673A1/en active Pending
- 2016-09-15 US US15/759,148 patent/US10633445B2/en active Active
- 2016-09-15 CN CN201680066388.2A patent/CN108430506A/zh active Pending
- 2016-09-15 KR KR1020187010458A patent/KR20180042449A/ko not_active Withdrawn
- 2016-09-15 JP JP2018513633A patent/JP7020687B2/ja not_active Expired - Fee Related
-
2020
- 2020-03-30 US US16/834,562 patent/US11548945B2/en active Active
- 2020-05-14 ZA ZA2020/02966A patent/ZA202002966B/en unknown
-
2021
- 2021-06-30 AU AU2021204534A patent/AU2021204534A1/en not_active Abandoned
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