JP2018527903A5 - - Google Patents

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Publication number
JP2018527903A5
JP2018527903A5 JP2018502692A JP2018502692A JP2018527903A5 JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5 JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5
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JP
Japan
Prior art keywords
seq
antibody
antigen
binding fragment
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018502692A
Other languages
English (en)
Japanese (ja)
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JP2018527903A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/043712 external-priority patent/WO2017015622A2/en
Publication of JP2018527903A publication Critical patent/JP2018527903A/ja
Publication of JP2018527903A5 publication Critical patent/JP2018527903A5/ja
Pending legal-status Critical Current

Links

JP2018502692A 2015-07-22 2016-07-22 Gdf11結合タンパク質およびその使用 Pending JP2018527903A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562195504P 2015-07-22 2015-07-22
US62/195,504 2015-07-22
US201662275068P 2016-01-05 2016-01-05
US62/275,068 2016-01-05
PCT/US2016/043712 WO2017015622A2 (en) 2015-07-22 2016-07-22 Gdf11 binding proteins and uses thereof

Publications (2)

Publication Number Publication Date
JP2018527903A JP2018527903A (ja) 2018-09-27
JP2018527903A5 true JP2018527903A5 (https=) 2019-10-17

Family

ID=57834686

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018502692A Pending JP2018527903A (ja) 2015-07-22 2016-07-22 Gdf11結合タンパク質およびその使用

Country Status (6)

Country Link
US (1) US20180208648A1 (https=)
EP (1) EP3324996A4 (https=)
JP (1) JP2018527903A (https=)
AU (1) AU2016297248A1 (https=)
CA (1) CA3031430A1 (https=)
WO (1) WO2017015622A2 (https=)

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Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
DK3496739T3 (da) 2016-07-15 2021-05-10 Acceleron Pharma Inc Sammensætninger omfattende actriia-polypeptider til brug i behandlingen af pulmonal hypertension
US20200031895A1 (en) * 2016-12-16 2020-01-30 Biogen Ma Inc. Stabilized proteolytically activated growth differentiation factor 11
US20200155481A1 (en) * 2017-05-03 2020-05-21 The Johns Hopkins University Intramuscular atovaquone for malaria prophylaxis
KR102439221B1 (ko) 2017-12-14 2022-09-01 프로디자인 소닉스, 인크. 음향 트랜스듀서 구동기 및 제어기
KR102646145B1 (ko) 2018-05-31 2024-03-11 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물
SI3677278T1 (sl) 2018-07-11 2022-01-31 Scholar Rock, Inc. Izoformno selektivni zaviralci TGFBETA1 in uporaba le-teh
MA53125A (fr) 2018-07-11 2021-05-19 Scholar Rock Inc Inhibiteurs de tgf?1 sélectifs selon l'isoforme à affinité élevée
WO2020023310A1 (en) * 2018-07-20 2020-01-30 Williams Eva Compositions of fcrn antibodies and methods of use thereof
CN113518783A (zh) 2018-07-20 2021-10-19 动量制药公司 FcRn抗体组合物
KR102058961B1 (ko) 2018-07-28 2019-12-24 주식회사 엑소코바이오 엑소좀의 동결건조 방법
KR102163806B1 (ko) * 2018-07-30 2020-10-07 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물
CN116199780A (zh) * 2019-12-24 2023-06-02 美勒斯公司 TGF-β-RII结合蛋白质
RU2750267C1 (ru) * 2020-02-07 2021-06-25 Общество с ограниченной ответственностью «НАУЧНО-ПРОИЗВОДСТВЕННОЕ ОБЪЕДИНЕНИЕ ИН-ВЕТ» Рекомбинантный ростовой дифференцировочный фактор роста 11 (GDF11), способ его получения, инъекционный препарат для повышения мышечной массы млекопитающих животных и птицы, а также способ использования препарата
US20230174620A1 (en) 2020-04-28 2023-06-08 Acceleron Pharma Inc. Actrii proteins and use in treating post-capillary pulmonary hypertension

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US20030167492A1 (en) * 1994-07-08 2003-09-04 Johns Hopkins University School Of Medicine Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same
EP1574577A3 (en) * 1994-07-08 2006-06-14 The Johns Hopkins University School Of Medicine Growth differentiation factor-11
CA2336536A1 (en) * 1998-07-28 2000-02-10 The Johns Hopkins University School Of Medicine Growth differentiation factor-11
WO2004009776A2 (en) * 2002-07-19 2004-01-29 Abbott Biotechnology Ltd. TREATMENT OF TNFα RELATED DISORDERS
US7850962B2 (en) * 2004-04-20 2010-12-14 Genmab A/S Human monoclonal antibodies against CD20
TW200918553A (en) * 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
JP5841845B2 (ja) * 2009-02-24 2016-01-13 ソーク・インステチュート・フォー・バイオロジカル・スタディーズSalk Institute For Biological Studies TGF−βスーパーファミリーのデザイナーリガンド
PT3904391T (pt) * 2010-03-10 2024-10-14 Genmab As Anticorpos monoclonais contra c-met
WO2013071056A2 (en) * 2011-11-11 2013-05-16 Duke University Combination drug therapy for the treatment of solid tumors
WO2013148284A1 (en) * 2012-03-29 2013-10-03 Genentech, Inc. Antibodies that bind to a pcsk9 cleavage site and methods of use
WO2013165972A2 (en) * 2012-04-30 2013-11-07 Cell Signaling Technology, Inc. Anti-hepatitis b virus antibodies and use thereof
JP2016500704A (ja) * 2012-11-06 2016-01-14 スカラー ロック インコーポレイテッドScholar Rock,Inc. 細胞シグナル伝達を変調するための組成物及び方法
RS61778B1 (sr) * 2013-05-06 2021-06-30 Scholar Rock Inc Kompozicije i postupci za modulaciju faktora rasta
WO2016073906A2 (en) * 2014-11-06 2016-05-12 Scholar Rock, Inc. Transforming growth factor-related immunoassays

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