JP2018526352A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018526352A5 JP2018526352A5 JP2018506301A JP2018506301A JP2018526352A5 JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5 JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- substituted
- optionally
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SMXLVZARNMVEKM-FJFCPSMQSA-N Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F Chemical compound Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F SMXLVZARNMVEKM-FJFCPSMQSA-N 0.000 description 1
- WUEFBSDYTXRVSZ-VJQNXJLFSA-N Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F Chemical compound Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F WUEFBSDYTXRVSZ-VJQNXJLFSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15180175 | 2015-08-07 | ||
| EP15180175.0 | 2015-08-07 | ||
| EP15199739 | 2015-12-14 | ||
| EP15199739.2 | 2015-12-14 | ||
| PCT/EP2016/068291 WO2017025368A1 (en) | 2015-08-07 | 2016-08-01 | Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018526352A JP2018526352A (ja) | 2018-09-13 |
| JP2018526352A5 true JP2018526352A5 (enExample) | 2020-11-05 |
| JP6816107B2 JP6816107B2 (ja) | 2021-01-20 |
Family
ID=56618142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506301A Expired - Fee Related JP6816107B2 (ja) | 2015-08-07 | 2016-08-01 | インダニルアミノピリジルシクロプロパンカルボン酸、医薬組成物及びこれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9617251B2 (enExample) |
| EP (1) | EP3331860B1 (enExample) |
| JP (1) | JP6816107B2 (enExample) |
| WO (1) | WO2017025368A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110312706B (zh) * | 2016-11-28 | 2023-08-18 | 勃林格殷格翰国际有限公司 | 茚满基氨基吡啶基环丙烷甲酸、其药物组合物及用途 |
| JP6968181B2 (ja) * | 2017-01-26 | 2021-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インダニルアミノピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用 |
| JOP20180040A1 (ar) * | 2017-04-20 | 2019-01-30 | Gilead Sciences Inc | مثبطات pd-1/pd-l1 |
| UA126458C2 (uk) | 2018-02-13 | 2022-10-05 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| WO2019165043A2 (en) | 2018-02-22 | 2019-08-29 | Chemocentryx, Inc. | Indane-amines as pd-l1 antagonists |
| US12083118B2 (en) | 2018-03-29 | 2024-09-10 | Arbutus Biopharma Corporation | Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same |
| US10899735B2 (en) | 2018-04-19 | 2021-01-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| EP3820572B1 (en) | 2018-07-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| EP3865477B1 (en) * | 2018-10-10 | 2023-07-12 | Korea Research Institute of Bioscience and Biotechnology | Carbene compound, carbene-metal nanoparticle complex and preparation method thereof |
| AU2019366355B2 (en) | 2018-10-24 | 2022-10-13 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| WO2021071837A1 (en) | 2019-10-07 | 2021-04-15 | Kallyope, Inc. | Gpr119 agonists |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| UY39222A (es) | 2020-05-19 | 2021-11-30 | Kallyope Inc | Activadores de la ampk |
| AU2021297323A1 (en) | 2020-06-26 | 2023-02-16 | Kallyope, Inc. | AMPK activators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1559422B1 (en) | 2002-11-08 | 2014-04-30 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| WO2005087710A1 (ja) * | 2004-03-15 | 2005-09-22 | Takeda Pharmaceutical Company Limited | アミノフェニルプロパン酸誘導体 |
| WO2007033002A1 (en) * | 2005-09-14 | 2007-03-22 | Amgen Inc. | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| US8633182B2 (en) * | 2012-05-30 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Indanyloxyphenylcyclopropanecarboxylic acids |
| WO2015024526A1 (en) * | 2013-08-23 | 2015-02-26 | Fujian Haixi Pharmaceuticals Co., Ltd | Carboxylic acid compounds in treatment of diabetes mellitus |
-
2016
- 2016-08-01 EP EP16750134.5A patent/EP3331860B1/en active Active
- 2016-08-01 US US15/225,038 patent/US9617251B2/en active Active
- 2016-08-01 JP JP2018506301A patent/JP6816107B2/ja not_active Expired - Fee Related
- 2016-08-01 WO PCT/EP2016/068291 patent/WO2017025368A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018526352A5 (enExample) | ||
| JP2018526405A5 (enExample) | ||
| JP2020505393A5 (enExample) | ||
| JP2020505400A5 (enExample) | ||
| JP2019535792A5 (enExample) | ||
| JP2020505394A5 (enExample) | ||
| JP2020514315A5 (enExample) | ||
| JP2020506205A5 (enExample) | ||
| RU2403258C2 (ru) | Тиазолилдигидроиндазолы | |
| JP2019532110A5 (enExample) | ||
| JP2015531366A5 (enExample) | ||
| CL2020000363A1 (es) | Inhibidores macrocíclicos de mcl-1 y métodos de uso. | |
| IL274229B2 (en) | Antibacterial compounds | |
| JP2019504050A5 (enExample) | ||
| EP4458348A3 (en) | Pharmaceutical compositions containing substituted polycyclic pyridone derivatives and prodrug thereof | |
| JP2015504081A5 (enExample) | ||
| JP2021504317A5 (enExample) | ||
| MX2020014116A (es) | Agente profilactico o terapeutico para atrofia muscular espinal. | |
| RU2014135401A (ru) | Производные пиридона | |
| JP2017511360A5 (enExample) | ||
| HRP20120696T1 (hr) | Spiro-prstenasti spoj i njegova medicinska upotreba | |
| JP2015516427A5 (enExample) | ||
| RU2019130519A (ru) | 4-пиридоновое соединение или его соль, фармацевтическая композиция и содержащий их состав | |
| JP2016534084A5 (enExample) | ||
| RU2016134749A (ru) | Гетероциклическое сульфонамидное производное и лекарственное средство, содержащее такое производное |