JP2020505394A5 - - Google Patents
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- JP2020505394A5 JP2020505394A5 JP2019540033A JP2019540033A JP2020505394A5 JP 2020505394 A5 JP2020505394 A5 JP 2020505394A5 JP 2019540033 A JP2019540033 A JP 2019540033A JP 2019540033 A JP2019540033 A JP 2019540033A JP 2020505394 A5 JP2020505394 A5 JP 2020505394A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- cycloalkyl
- optionally
- replaced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17153381 | 2017-01-26 | ||
| EP17153381.3 | 2017-01-26 | ||
| PCT/EP2018/051383 WO2018138026A1 (en) | 2017-01-26 | 2018-01-22 | Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020505394A JP2020505394A (ja) | 2020-02-20 |
| JP2020505394A5 true JP2020505394A5 (enExample) | 2021-01-21 |
| JP6968181B2 JP6968181B2 (ja) | 2021-11-17 |
Family
ID=57906574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019540033A Active JP6968181B2 (ja) | 2017-01-26 | 2018-01-22 | インダニルアミノピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10253004B2 (enExample) |
| EP (1) | EP3573965B1 (enExample) |
| JP (1) | JP6968181B2 (enExample) |
| CN (1) | CN110214135B (enExample) |
| AR (1) | AR110777A1 (enExample) |
| TW (1) | TW201840541A (enExample) |
| WO (1) | WO2018138026A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10793530B2 (en) * | 2017-01-26 | 2020-10-06 | Boehringer Ingelheim International Gmbh | Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| CN110198928B (zh) * | 2017-01-26 | 2023-08-29 | 勃林格殷格翰国际有限公司 | 苄氧基吡啶基环丙烷甲酸、其药物组合物和用途 |
| WO2018138030A1 (en) * | 2017-01-26 | 2018-08-02 | Boehringer Ingelheim International Gmbh | Benzyloxypyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CR20200347A (es) | 2018-02-13 | 2020-09-23 | Gilead Sciences Inc | Inhibidores pd-1/pd-l1 |
| TWI712412B (zh) | 2018-04-19 | 2020-12-11 | 美商基利科學股份有限公司 | Pd‐1/pd‐l1抑制劑 |
| SG11202012425QA (en) | 2018-07-13 | 2021-01-28 | Gilead Sciences Inc | Pd-1/pd-l1 inhibitors |
| WO2020086556A1 (en) | 2018-10-24 | 2020-04-30 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR20220150270A (ko) | 2019-10-07 | 2022-11-10 | 칼리오페, 인크. | Gpr119 효능제 |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| CN116390925A (zh) | 2020-06-26 | 2023-07-04 | 卡尔优普公司 | Ampk活化剂 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US628476A (en) | 1898-03-18 | 1899-07-11 | Joseph Howard Kirk | Junction of cycle, motor-car, or other frames, &c. |
| US7704995B2 (en) * | 2002-05-03 | 2010-04-27 | Exelixis, Inc. | Protein kinase modulators and methods of use |
| CA2505322A1 (en) | 2002-11-08 | 2004-05-21 | Takeda Pharmaceutical Company Limited | Receptor function regulator |
| DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| CN101111486A (zh) * | 2005-01-31 | 2008-01-23 | 默克公司 | 抗糖尿病二环化合物 |
| PE20061127A1 (es) | 2005-02-15 | 2006-10-21 | Glaxo Group Ltd | Derivados de propanosulfonamida que potencian el receptor de glutamato |
| EP1866278A1 (en) | 2005-03-28 | 2007-12-19 | Pfizer, Inc. | Substituted aryloxoethyl cyclopropanecarboxamide compounds as vr1 receptor antagonists |
| EP1924546A1 (en) | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| WO2007104717A1 (en) | 2006-03-15 | 2007-09-20 | Neurosearch A/S | Quinazolinones and their use as potassium channels activators |
| KR20110027657A (ko) | 2008-06-25 | 2011-03-16 | 다이이찌 산쿄 가부시키가이샤 | 카르복실산 화합물 |
| WO2010051819A1 (en) | 2008-11-10 | 2010-05-14 | Neurosearch A/S | Novel 2,3-diamino-quinazolinone derivatives and their medical use |
| WO2011094890A1 (en) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators |
| US20120077814A1 (en) * | 2010-09-10 | 2012-03-29 | Zhong Wang | Sulfonamide, sulfamate, and sulfamothioate derivatives |
| US8642585B2 (en) | 2012-03-26 | 2014-02-04 | Boehringer Ingelheim International Gmbh | Indanyloxydihydrobenzofuranylacetic acids |
| US8633182B2 (en) * | 2012-05-30 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Indanyloxyphenylcyclopropanecarboxylic acids |
| EP3049396B1 (en) | 2013-09-26 | 2017-11-15 | Boehringer Ingelheim International GmbH | Process and intermediates for preparing indanyloxydihydrobenzofuranyl acetic acid derivatives as gpr40 agonists |
| EP3074375B1 (en) * | 2013-11-28 | 2018-04-04 | Boehringer Ingelheim International GmbH | New indanyloxyphenylcyclopropanecarboxylic acids |
| JP6816107B2 (ja) * | 2015-08-07 | 2021-01-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インダニルアミノピリジルシクロプロパンカルボン酸、医薬組成物及びこれらの使用 |
| EP3347358B1 (en) * | 2015-09-09 | 2019-11-27 | Boehringer Ingelheim International GmbH | [{[2,3-dihydro-1h-inden-1-yl]amino}-2h,3h-furo[3,2-b]pyridin-3-yl]acetic acids, pharmaceutical compositions and uses thereof |
| US10919859B2 (en) * | 2017-01-26 | 2021-02-16 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| WO2018138030A1 (en) * | 2017-01-26 | 2018-08-02 | Boehringer Ingelheim International Gmbh | Benzyloxypyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| CN110198928B (zh) * | 2017-01-26 | 2023-08-29 | 勃林格殷格翰国际有限公司 | 苄氧基吡啶基环丙烷甲酸、其药物组合物和用途 |
| US10793530B2 (en) * | 2017-01-26 | 2020-10-06 | Boehringer Ingelheim International Gmbh | Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
-
2018
- 2018-01-22 JP JP2019540033A patent/JP6968181B2/ja active Active
- 2018-01-22 EP EP18703219.8A patent/EP3573965B1/en active Active
- 2018-01-22 US US15/876,237 patent/US10253004B2/en active Active
- 2018-01-22 WO PCT/EP2018/051383 patent/WO2018138026A1/en not_active Ceased
- 2018-01-22 CN CN201880007924.0A patent/CN110214135B/zh active Active
- 2018-01-25 AR ARP180100172A patent/AR110777A1/es unknown
- 2018-01-25 TW TW107102700A patent/TW201840541A/zh unknown
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