JP2018524336A5 - - Google Patents
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- JP2018524336A5 JP2018524336A5 JP2017567321A JP2017567321A JP2018524336A5 JP 2018524336 A5 JP2018524336 A5 JP 2018524336A5 JP 2017567321 A JP2017567321 A JP 2017567321A JP 2017567321 A JP2017567321 A JP 2017567321A JP 2018524336 A5 JP2018524336 A5 JP 2018524336A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- haloalkyl
- group
- halogen
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 229910052736 halogen Inorganic materials 0.000 claims description 48
- 150000002367 halogens Chemical class 0.000 claims description 48
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 44
- 125000000217 alkyl group Chemical group 0.000 claims description 35
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims description 31
- 125000001424 substituent group Chemical group 0.000 claims description 31
- 150000001875 compounds Chemical class 0.000 claims description 25
- 229910052739 hydrogen Inorganic materials 0.000 claims description 24
- 239000001257 hydrogen Substances 0.000 claims description 24
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims description 21
- -1 C 1 -C 6 alkyl Chemical group 0.000 claims description 21
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 18
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 18
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 16
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 16
- 125000003545 alkoxy group Chemical group 0.000 claims description 16
- 125000004122 cyclic group Chemical group 0.000 claims description 16
- 125000004770 (C1-C4) haloalkylsulfanyl group Chemical group 0.000 claims description 14
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 14
- 229910052717 sulfur Inorganic materials 0.000 claims description 14
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 13
- 125000004740 (C1-C6) haloalkylsulfanyl group Chemical group 0.000 claims description 12
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims description 12
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims description 12
- 229910052760 oxygen Inorganic materials 0.000 claims description 12
- 125000004771 (C1-C4) haloalkylsulfinyl group Chemical group 0.000 claims description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 10
- 125000001188 haloalkyl group Chemical group 0.000 claims description 10
- 239000001301 oxygen Substances 0.000 claims description 10
- 239000011593 sulfur Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 229910052757 nitrogen Inorganic materials 0.000 claims description 9
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 9
- 125000004768 (C1-C4) alkylsulfinyl group Chemical group 0.000 claims description 8
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 claims description 8
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims description 8
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 8
- 241000607479 Yersinia pestis Species 0.000 claims description 8
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 8
- 150000002431 hydrogen Chemical class 0.000 claims description 8
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims description 7
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims description 6
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims description 6
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims description 6
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims description 6
- 229920006395 saturated elastomer Polymers 0.000 claims description 6
- 125000003118 aryl group Chemical group 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 5
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims description 4
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 claims description 4
- 150000001204 N-oxides Chemical class 0.000 claims description 4
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical group C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims description 4
- 125000000304 alkynyl group Chemical group 0.000 claims description 4
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims description 4
- 125000005842 heteroatom Chemical group 0.000 claims description 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 4
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims description 4
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 125000004434 sulfur atom Chemical group 0.000 claims description 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims description 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 150000001412 amines Chemical group 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims description 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 2
- 239000012752 auxiliary agent Substances 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 description 7
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 description 7
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 description 6
- 125000006310 cycloalkyl amino group Chemical group 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 description 2
- 125000000232 haloalkynyl group Chemical group 0.000 description 2
- 241000256186 Anopheles <genus> Species 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 description 1
- 230000001548 androgenic effect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15174760.7 | 2015-07-01 | ||
| EP15174760 | 2015-07-01 | ||
| EP15184065 | 2015-09-07 | ||
| EP15184065.9 | 2015-09-07 | ||
| PCT/EP2016/064784 WO2017001314A1 (en) | 2015-07-01 | 2016-06-27 | Pesticidally active polycyclic derivatives with sulfur containing substituents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018524336A JP2018524336A (ja) | 2018-08-30 |
| JP2018524336A5 true JP2018524336A5 (cg-RX-API-DMAC10.html) | 2019-08-08 |
Family
ID=56203412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017567321A Ceased JP2018524336A (ja) | 2015-07-01 | 2016-06-27 | 硫黄含有置換基を有する有害生物防除に活性な多環式誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10745396B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3317276B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2018524336A (cg-RX-API-DMAC10.html) |
| CN (1) | CN107735396B (cg-RX-API-DMAC10.html) |
| BR (1) | BR112017028600A2 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2017001314A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018537460A (ja) * | 2015-11-23 | 2018-12-20 | シンジェンタ パーティシペーションズ アーゲー | 硫黄およびシクロプロピル含有置換基を有する有害生物防除的に活性な複素環式誘導体 |
| BR112019008492B1 (pt) | 2016-10-27 | 2024-01-30 | Syngenta Participations Ag | Compostos derivados heterocíclicos ativos em termos pesticidas com substituintes contendo enxofre e hidroxilamina, composição pesticida, método para controle de pragas e método para a proteção de material de propagação de plantas do ataque por pragas |
| JPWO2018163818A1 (ja) * | 2017-03-06 | 2020-01-09 | 住友化学株式会社 | トリアゾール化合物の製造方法 |
| UA125047C2 (uk) | 2017-05-10 | 2021-12-29 | Басф Се | Біциклічні пестицидні сполуки |
| EP3453706A1 (en) | 2017-09-08 | 2019-03-13 | Basf Se | Pesticidal imidazole compounds |
| EP3684768B1 (en) * | 2017-09-18 | 2024-01-24 | Syngenta Participations AG | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| CN111741958A (zh) | 2018-02-21 | 2020-10-02 | 拜耳公司 | 作为害虫防治剂的稠合双环杂环衍生物 |
| EP3765466B1 (de) | 2018-03-12 | 2022-05-25 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3906239A1 (en) | 2018-12-31 | 2021-11-10 | Syngenta Crop Protection AG | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| WO2020141135A1 (en) * | 2018-12-31 | 2020-07-09 | Syngenta Crop Protection Ag | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| TW202045011A (zh) * | 2019-02-28 | 2020-12-16 | 瑞士商先正達農作物保護公司 | 具有含硫取代基之殺有害生物活性雜環衍生物 |
| CN112062759B (zh) * | 2020-09-08 | 2021-11-23 | 浙江工业大学 | 含乙砜基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用 |
| CN111943944B (zh) * | 2020-09-08 | 2021-11-23 | 浙江工业大学 | 含乙硫基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用 |
| CN120882309A (zh) | 2023-03-14 | 2025-10-31 | 先正达农作物保护股份公司 | 对杀昆虫剂具有抗性的有害生物的控制 |
| WO2025010291A2 (en) * | 2023-07-03 | 2025-01-09 | The General Hospital Corporation | Targeted epigenetic therapies for disorders of progranulin deficiency |
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| US10005775B2 (en) * | 2014-08-12 | 2018-06-26 | Syngenta Participations, Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
| ES2924890T3 (es) * | 2015-01-19 | 2022-10-11 | Syngenta Participations Ag | Derivados policíclicos activos como plaguicidas con sustituyentes que contienen azufre |
| US10323031B2 (en) * | 2015-03-12 | 2019-06-18 | Syngenta Participations Ag | Pesticidally active tetracyclic derivatives with sulfur containing substituents |
| WO2016169882A1 (en) * | 2015-04-24 | 2016-10-27 | Syngenta Participations Ag | Pesticidally active polycyclic derivatives with sulfur substituted five membered ring heterocyles |
-
2016
- 2016-06-27 CN CN201680038595.7A patent/CN107735396B/zh not_active Expired - Fee Related
- 2016-06-27 JP JP2017567321A patent/JP2018524336A/ja not_active Ceased
- 2016-06-27 US US15/732,803 patent/US10745396B2/en not_active Expired - Fee Related
- 2016-06-27 EP EP16731936.7A patent/EP3317276B1/en not_active Not-in-force
- 2016-06-27 BR BR112017028600A patent/BR112017028600A2/pt not_active Application Discontinuation
- 2016-06-27 WO PCT/EP2016/064784 patent/WO2017001314A1/en not_active Ceased