JP2018523703A5 - - Google Patents
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- JP2018523703A5 JP2018523703A5 JP2018521713A JP2018521713A JP2018523703A5 JP 2018523703 A5 JP2018523703 A5 JP 2018523703A5 JP 2018521713 A JP2018521713 A JP 2018521713A JP 2018521713 A JP2018521713 A JP 2018521713A JP 2018523703 A5 JP2018523703 A5 JP 2018523703A5
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- JP
- Japan
- Prior art keywords
- peptide
- inflammatory
- composition
- amino acid
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000003110 anti-inflammatory Effects 0.000 claims 8
- 200000000018 inflammatory disease Diseases 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 150000001413 amino acids Chemical class 0.000 claims 6
- 108091005593 modified peptides Proteins 0.000 claims 3
- 238000010348 incorporation Methods 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- 210000004072 Lung Anatomy 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 210000003491 Skin Anatomy 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 102000004965 antibodies Human genes 0.000 claims 1
- 108090001123 antibodies Proteins 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 230000000271 cardiovascular Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000000968 intestinal Effects 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000006011 modification reaction Methods 0.000 claims 1
- 238000010647 peptide synthesis reaction Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Claims (13)
- 配列番号３４３または３４４から選択されるペプチド。
- 請求項1に記載のペプチドと比較して１〜３個のアミノ酸の変更を有し、そのアミノ酸の変更または各々のアミノ酸の変更が、アミノ酸の挿入、付加、欠失および置換から選択される請求項１に記載のペプチドの抗炎症性変異体。
- 請求項1に記載のペプチドと比較して１〜２個のアミノ酸の変更を有する請求項２に記載のペプチドの抗炎症性変異体。
- 請求項1に記載のペプチドと比較して１個のアミノ酸の変更を有する請求項１に記載のペプチドの抗炎症性変異体。
- 側鎖への修飾、保護基の組込み、ペプチド合成の間の非天然アミノ酸および／またはそれらの誘導体の組込み、並びに、架橋剤及び、ペプチドにコンホーメーションの制約を課す他の方法の使用によって化学的に修飾される、請求項１に記載のペプチド、または請求項２〜４のいずれか１項に記載の抗炎症性変異体。
- 結合パートナーと、コンジュゲートされた、連結された、または融合された、請求項１に記載のペプチドまたは請求項２〜４のいずれか１項に記載の抗炎症性変異体を含むコンジュゲート。
- 前記結合パートナーが、ポリエチレングリコールポリマー、分子量を増大する化合物、親油性基、または抗体分子から選択される、請求項６に記載のコンジュゲート。
- 請求項１に記載の１または複数のペプチド、請求項２〜４のいずれか１項に記載の抗炎症性変異体、または請求項５または６に記載の化学的に修飾されたペプチドを含む組成物。
- 配列番号３４３および配列番号３４４を含む、請求項８に記載の組成物。
- 粉末である、請求項８または９のいずれかに記載の組成物。
- 請求項８から１０のいずれか１項に記載の組成物を含む、食物または飲料、栄養補助食品、パーソナルケア組成物、または医薬組成物。
- 哺乳動物における炎症または炎症性障害の治療または予防のための方法における使用のための、請求項１に記載のペプチド、請求項２〜４のいずれか１項に記載の抗炎症性変異体、請求項５または６に記載の化学的に修飾されたペプチド、または、請求項８から１１のいずれか１項に記載の組成物。
- 炎症性障害は、皮膚の炎症性障害、関節の炎症性障害、心血管系の炎症性障害、肺または気道の炎症性障害および腸の炎症性障害から選択される、請求項１に記載のペプチド、請求項２〜４のいずれか１項に記載の抗炎症性変異体、請求項５または６に記載の化学的に修飾されたペプチド、または、請求項８から１１のいずれか１項に記載の組成物もしくは請求項１２に記載の使用のための組成物。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021173218A JP7288026B2 (ja) | 2015-07-16 | 2021-10-22 | 抗炎症性ペプチドおよびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15177013.8 | 2015-07-16 | ||
| EP15177017.9A EP3118216A1 (en) | 2015-07-16 | 2015-07-16 | Cellular growth and proliferation promoting peptides, and uses thereof |
| EP15177017.9 | 2015-07-16 | ||
| EP15177013.8A EP3118215A1 (en) | 2015-07-16 | 2015-07-16 | Anti-inflammatory peptides, and uses thereof |
| PCT/EP2016/067090 WO2017009484A1 (en) | 2015-07-16 | 2016-07-18 | Anti-inflammatory peptides, and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021173218A Division JP7288026B2 (ja) | 2015-07-16 | 2021-10-22 | 抗炎症性ペプチドおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018523703A JP2018523703A (ja) | 2018-08-23 |
| JP2018523703A5 true JP2018523703A5 (ja) | 2019-08-22 |
Family
ID=56686757
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018521713A Pending JP2018523703A (ja) | 2015-07-16 | 2016-07-18 | 抗炎症性ペプチドおよびその使用 |
| JP2021173218A Active JP7288026B2 (ja) | 2015-07-16 | 2021-10-22 | 抗炎症性ペプチドおよびその使用 |
| JP2023086030A Pending JP2023109950A (ja) | 2015-07-16 | 2023-05-25 | 抗炎症性ペプチドおよびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021173218A Active JP7288026B2 (ja) | 2015-07-16 | 2021-10-22 | 抗炎症性ペプチドおよびその使用 |
| JP2023086030A Pending JP2023109950A (ja) | 2015-07-16 | 2023-05-25 | 抗炎症性ペプチドおよびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10463591B2 (ja) |
| EP (3) | EP3322430B1 (ja) |
| JP (3) | JP2018523703A (ja) |
| KR (3) | KR102576571B1 (ja) |
| CN (2) | CN114835784A (ja) |
| AU (2) | AU2016293129B2 (ja) |
| BR (1) | BR112018000660A2 (ja) |
| CA (1) | CA2992378A1 (ja) |
| DK (1) | DK3322430T3 (ja) |
| ES (1) | ES2806989T3 (ja) |
| MX (2) | MX2018000697A (ja) |
| WO (1) | WO2017009484A1 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3548058B1 (en) * | 2016-12-05 | 2022-06-22 | Nuritas Limited | Compositions comprising peptide wkdeagkplvk |
| KR102354916B1 (ko) * | 2020-02-11 | 2022-01-26 | 주식회사 쓰리빅스 | 신규 펩타이드 3ps_i014 및 이의 용도 |
| FR3114744B1 (fr) | 2020-10-02 | 2024-01-05 | Basf Beauty Care Solutions France Sas | Nouvelle utilisation d’un peptide pour améliorer le confort de la peau et/ou des muqueuses et/ou l’apparence des phanères |
| US20240043474A1 (en) * | 2020-12-16 | 2024-02-08 | Ajou University Industry-Academic Cooperation Foundation | Anti-inflammatory peptide for preventing or treating atopic dermatitis |
| CN114478702B (zh) * | 2022-04-06 | 2023-12-12 | 中南林业科技大学 | 一种米糠来源短肽及其在治疗皮肤损伤中的应用 |
| CN116253782B (zh) * | 2022-09-08 | 2024-06-04 | 浙江大学 | 一种广谱抗菌肽ktr及其应用 |
| CN116375828B (zh) * | 2022-09-08 | 2024-06-04 | 浙江大学 | 一种具有抗菌活性的抗菌肽kta及其应用 |
| FR3141066A1 (fr) | 2022-10-24 | 2024-04-26 | Basf Beauty Care Solutions France Sas | Nouvelle utilisation d’un peptide pour améliorer la matrice extracellulaire du derme de la peau et/ou des muqueuses |
| CN116491631B (zh) * | 2023-05-26 | 2024-06-25 | 青岛农业大学 | 一种预制菜红烧肉及其制备方法 |
| CN117736271A (zh) * | 2023-06-29 | 2024-03-22 | 长沙理工大学 | 一种米渣蛋白源免疫活性肽及其应用 |
| CN117986337A (zh) * | 2024-02-02 | 2024-05-07 | 北京川晋生物科技有限公司 | 一种提高免疫力的益生菌组合物以及在治疗疾病中的应用 |
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| US4261975A (en) | 1979-09-19 | 1981-04-14 | Merck & Co., Inc. | Viral liposome particle |
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-
2016
- 2016-07-18 BR BR112018000660-2A patent/BR112018000660A2/pt active Search and Examination
- 2016-07-18 AU AU2016293129A patent/AU2016293129B2/en active Active
- 2016-07-18 KR KR1020217030710A patent/KR102576571B1/ko active IP Right Grant
- 2016-07-18 US US15/744,304 patent/US10463591B2/en active Active
- 2016-07-18 CN CN202111590603.8A patent/CN114835784A/zh active Pending
- 2016-07-18 JP JP2018521713A patent/JP2018523703A/ja active Pending
- 2016-07-18 ES ES16751491T patent/ES2806989T3/es active Active
- 2016-07-18 CA CA2992378A patent/CA2992378A1/en active Pending
- 2016-07-18 KR KR1020237030244A patent/KR20230132623A/ko active Application Filing
- 2016-07-18 WO PCT/EP2016/067090 patent/WO2017009484A1/en active Application Filing
- 2016-07-18 CN CN201680051932.6A patent/CN108348568B/zh active Active
- 2016-07-18 KR KR1020187004160A patent/KR102307260B1/ko active IP Right Grant
- 2016-07-18 DK DK16751491.8T patent/DK3322430T3/da active
- 2016-07-18 MX MX2018000697A patent/MX2018000697A/es active IP Right Grant
- 2016-07-18 EP EP16751491.8A patent/EP3322430B1/en active Active
- 2016-07-18 EP EP20165063.7A patent/EP3747425A1/en not_active Withdrawn
- 2016-07-18 EP EP21178569.6A patent/EP3954700A1/en active Pending
-
2018
- 2018-01-16 MX MX2020010806A patent/MX2020010806A/es unknown
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2019
- 2019-09-12 US US16/569,159 patent/US11253456B2/en active Active
-
2021
- 2021-04-21 AU AU2021202423A patent/AU2021202423A1/en active Pending
- 2021-10-22 JP JP2021173218A patent/JP7288026B2/ja active Active
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2022
- 2022-01-13 US US17/574,865 patent/US11779531B2/en active Active
-
2023
- 2023-05-25 JP JP2023086030A patent/JP2023109950A/ja active Pending
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